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Name: Kumar Vedantham Desired

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E-Mail: Willing

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Looking: Industry

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PHARMACEUTICAL SCIENTIST

Pharmaceutics Engineering Medical / Pharmaceutical Product Design

Scientist I/II Biopharm Development, Formulation Scientist, Preformulation Scientist, Associate Research Scientist, Research associate, Product development Scientist, Staff RD Engineer, Industrial Post Doctoral Fellow

Chemical engineer and soon-to-be degreed Ph.D. in Pharmaceutics with interest in new product formulation. Experience working for pharmaceutical companies, university teaching, and research with publications and conference presentations. Solid talent in applying chemical engineering principles to pharmaceutical environment to develop new methods for product design and development. Strong interest in translational research and technology transfer from diverse fields to pharmaceutical or medical product development in order to optimize development and speed products to market. Fluent English and Tamil; conversational Hindi. Travel and/or relocation acceptable.

* Strong theoretical background in drug delivery and solid state fundamentals and characterization (DSC, TGA).

* Effective liaison between engineers, process chemists and scientists working within production and scale up.

* Self-motivated critical thinker and independent worker using creative application of scientific principles.

* Excellent team playing capability and ability to meet challenges and deadlines.

Atomic Force Microscope - JEOL Scanning Electron Microscope HPLC - Gel Electrophoresis Infrared Spectroscopy - UV-VIS Spectrophotometer - Renishaw Raman Microscope - XRD (Siemens Diffraktometer D5000) - Data Acquisition Software such as CAMILE TG (Process Monitoring And Control System) - LASENTEC (Size Distribution Analysis System) Microtrac S5000 Particle Sizer - Tablet Manufacturing Process/Testing/Characterization - cGMP Documentation including Batch Records - Standard Operating Procedure For Instruments (SOP) - High Shear and Fluid Bed Granulator - Accela Tablet Coating Pan - Stokes Tablet Compression Machine - Data Acquisition Software such as CAMILE TG (Process Monitoring And Control System) - LASENTEC (Size Distribution Analysis System)

Confocal Raman Microscope - Cell Culture Technique

EDUCATION / AFFILIATIONS

PURDUE UNIVERSITY, West Lafayette, Indiana

Ph.D., Industrial and Physical Pharmacy, expected August, 2008

* Ross Research Fellowship, 2004-2005

* Dollen Scholarship, 2006-2007

* Dissertation: Development of an Anti-Thrombogenic Drug Eluting Stent Combinatorial Drug Approach

MISSISSIPPI STATE UNIVERSITY, Starkville, MS

Master of Science in Chemical Engineering, 2004

* Thesis: Effect of Operating Parameters on Particle Shape Distribution in a Crystallizer

UNIVERSITY OF MADRAS, India

BTech, Chemical Engineering, 2001

Controlled Release Society

American Association of Pharmaceutical Scientists

Society of Omega Chi Epsilon, 2003

SIGNIFICANT ACHIEVEMENTS DURING DOCTORAL STUDIES

* Developed electrospraying coating technique for loading drugs and polymer onto cardiovascular implants (stents). Used formulations based on pro-healing strategies (combination of drugs) and biological combination strategies (combining protein and drug).

* Signaling pathway specific drug eluting stent. 1,3-Dipropyl-8-cyclopentyl xanthine (DPCPX) loaded metallic stents were developed with controlled release kinetics. (DPCPX) is known to prevent mitogenesis, thus proliferation and migration of smooth muscle cells in vitro.

* Developed a bioresorbable polymeric urethra stent, currently commercialized at Akina Inc., a small pharmaceutical company that designs drug delivery systems, www.akinainc.com. Poly (L-lactide-co-caprolactone) was synthesized and a novel electrospraying coating technology was used to develop the stent.

* In-situ determination of end point in fluid bed granulation in collaboration with the Center for Advancement of Manufacturing Pharmaceuticals (CAMP); feasibility of using laser probe for monitoring particle size of granules in-situ in fluid bed process was assessed.

PROFESSIONAL EXPERIENCE

PURDUE UNIVERSITY, West Lafayette, Indiana, 2004-Present

Graduate Research Assistant, Industrial and Physical Pharmacy

Instructor, Dissolution Lab, 2006

Perform independent research for NIH-funded and industry-collaborated projects, with full responsibility for monthly progress reporting. Teach laboratory for bachelor level students.

* Commercialized a technique and developed a device currently used at a pharmaceutical company.

* Successfully developed new formulation strategies including prohealing strategies (combining drugs) and biological combinations (proteins and drugs) for improving the current drug eluting stent technology.

* Effectively taught over 200 lab students as demonstrated by increased student performance measured by percent scores as compared to previous years.

* Collaborate successfully with biomedical engineering department and Indianapolis Medical Center.

* Serve as Group Leader for graduate level lab course in Advanced Manufacturing Operations that involved acetaminophen tablet production. Results included passing all regulatory compliance issues, securing a top position in competition with 5 other groups.

* Served as part of the organization team for the 2nd Annual Korean Institute of Science and Technology/Purdue symposium held at Purdue on 2007.

MISSISSIPPI STATE UNIVERSITY, Starkville, Mississippi, 2002-2004

Graduate Research Assistant, Chemical Engineering

* Assisted in setting up the crystallization lab. Designed all protocols for conducting experiments for the National Science Foundation-funded project.

* Achieved critical results/observation in masters thesis that became instrument for an NSF grant renewal.

* Actively demonstrated self-motivation, organizational skills and independent research capability.

BRISTOL MYERS SQUIBB, New Brunswick, New York, Summer 2006

Industrial Intern

* In a team setting, developed an in vitro model for conducting a dissolution study for a compound formulated in a slow release subcutaneous dosage form. Results became the basis for further validation research into the method developed for a compound in clinical trials.

* Was recommended for a full-time job offer by supervisor.

PUBLICATIONS / CONFERENCE PRESENTATIONS / BOOK CHAPTERS

Journal

* Kumar Vedantham+, Eunah Kang+, Xin Long, Maria Dadara, Il-Keun Kwon, Michaele Sturek, and Kinam Park, Signal Pathway Specific Drug Eluting Stent: 1,3-Dipropyl-8-cyclopentyl xanthine (DPCPX), Submitted to Biomaterials (+ contributed equally for the study).

Conferences

* Development of an Anti-thrombogenic Drug Eluting Stent: Combinatorial Drug Approach, Kumar Vedantham, Il-Keun Kwon, Sungwon Kim, Kinam Park, Controlled Release Society, 2008.

* Development of an Anti-thrombogenic Drug Eluting Stent using Polymer based on 2-Methacryloyloxyethyl Phosphorylcholine (MPC), Kumar Vedantham, Sungwon Kim, Tomohiro Konno, Kazuhiko Ishihara, Kinam Park, American Association of Pharmaceutical Scientists (AAPS), 2008.

* Modeling of Coarse Particle Size and Shape Evolution during Attrition in a Stirred Vessel, Kumar Vedantham, Priscilla J. Hill, AIChE annual conference, November 2004.

* Stent for Delivery of 1,3-Dipropyl-8-cyclopentyl xanthine (DPCPX) - A Signaling Pathway Specific Drug, Eunah Kang, Kumar Vedantham, Xin Long, Maria Dadara, Il-Keun Kwon, Michael Sturek, and Kinam Park, Controlled Release Society, 2007.

Book Chapters

* Kumar Vedantham, and Kinam Park: Future outlook for drug eluting stents, in Drug device combination products: Delivery technologies and applications, Woodhead Publishing Limited, Chapter in progress.

* Il Keun Kwon, Sungwon Kim, Somali Chaterji, Kumar Vedantham, and Kinam Park: Smart drug delivery systems, in Smart Materials and Structures, Mel Schwartz, Ed., CRC, submitted.

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©2007 Bright and Professional - Web Resume

©2007 Bright and Professional - Web Resume

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