David Michael Markovitz, M.D.
Professor, Internal Medicine/Infectious Diseases
**** *. ******* ****** *****, 5220 MSRB III
Ann Arbor, MI 48109-5640
abqbgt@r.postjobfree.com
Education and Training
June 1972 St. Louis Park High School, St. Louis Park, Minnesota
August 1976 University of Minnesota, Minneapolis, Minnesota, B.A.
June 1981 University of Minnesota, Minneapolis, Minnesota, M.D.
June 1981-June 1984 Residency, University of Rochester Associated Hospitals Program in Internal Medicine, Rochester, New York
June 1984-June 1986 Fellowship, Infectious Diseases Unit, Department of Internal Medicine, University of Rochester School of Medicine, Rochester, New York
July 1986-June 1988 Research Fellowship, Lineberger Cancer Center, Laboratory of Dr. Joseph S. Pagano, Division of Infectious Diseases, University of North Carolina, Chapel Hill, North Carolina
Certification and Licensure
1988-present Michigan
1986-1988 North Carolina
1982-1988 New York
1986-present American Board of Internal Medicine/Infectious Diseases Subspecialty
1984-present American Board of Internal Medicine
Academic, Administrative, and Clinical Appointments
June 1988-August 1994 Assistant Professor, Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan
September 1994-Aug. 2002 Associate Professor (with tenure), Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan
September 2002-present Professor (with tenure), Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Michigan
Research Interests
Human Immunodeficiency Viruses Types 1 and 2Role of the DEK oncoprotein in cancer and inflammationRole of vimentin in microbial pathogenesis
Grants
Present and Active
Sponsor: Office of the Director, NIH/NCI (Transformative R01 Program)
Title: Replication of Endogenous Retroviruses in Modern Humans
PI: David M. Markovitz
Dates: 9/28/09-8/31/14
Funding Amount (total direct costs): $4,473,469
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID)
Title: DEK and TNF Inhibitors in Juvenile Arthritis
PI: David M. Markovitz
Dates: 9/1/09-8/31/13
Funding Amount (total direct costs): $1,000,000
Sponsor: Michigan Institute for Clinical and Health Research
Title: The DEK Oncoprotein as a Therapeutic Target in Melanoma
PI: David M. Markovitz
Dates: 9/1/09-8/31/10
Funding Amount (total direct costs): $50,000
Sponsor: Novartis Diagnostics
Title: The Endogenous Retrovirus HERV-K as a Cancer Biomarker
PI: David M. Markovitz
Dates: 6/1/09-6/30/11
Funding Amount (total direct costs): $55,000
Sponsor: Arthritis Foundation
Title: Posttranslational modifications of DEK and their role in autoimmunity
PI: Ferdinand Kappes
Dates: 7/1/06-6/30/10
Role: Mentor
Funding Amount (total direct costs): $150,000
Sponsor: National Institutes of Health
Title: Curcumin: A Multimechanism HIV Microbicide
PI: Raju C. Reddy
Dates: 9/25/08-8/31/10
Role: Co-investigator
Funding Amount (Markovitz): $25,000 in total direct costs to the Markovitz laboratory
Sponsor: National Institutes of Health
Title: Targeting HIV-1 Regulatory RNA Elements
PI: Hashim Al-Hashimi
Dates: 04/01/10-03/31/15
Role: Co-Investigator
Funding Amount: $79,710 in total direct costs to the Markovitz Laboratory
Sponsor: Michigan Institute for Clinical and Health Research
Title: The Role of DEK in the Development of Arthritis
PI: Nirit Mor-Vaknin, Ph.D.
Dates: 7/1/08-6/30/10
Role: Mentor
Funding Amount (total direct costs): $100,000
Sponsor: University of Michigan GI Peptide Research Center
Title: The Function of Vimentin in the Development of Chronic Gut Inflammation
PI: Nirit Mor-Vaknin
Dates: 9/1/09-8/31/10
Role: Mentor
Funding Amount (total direct costs): $25,000
Sponsor: National Institutes of Health (K01 award)
Title: The Role of DEK in the Development of Arthritis
PI: Nirit Mor-Vaknin
Dates: 7/1/09-5/31/14
Role: Co-Mentor
Funding Amount (total direct costs): $490,000
Previous (since 2001)
Sponsor: National Heart, Lung, and Blood Institute
Title: Chemokines and HIV replication in alveolar macrophages
PI: Michael Coffey
Dates: 10/1/96-7/30/01
Role: Co-PI
Funding Amount: $460,000
Sponsor: National Cancer Institute
Title: Great Lakes Regional Center for AIDS Research
PI: Steven Wolinsky
Dates: 9/1/98-8/31/01
Role: Co-investigator
Funding Amount: $183,000
Sponsor: American Cancer Society
Title: Mechanism of action and biological effect of the DEK oncoprotein
PI: David M. Markovitz
Dates: 7/1/98-6/30/01
Funding Amount: $255,000
Sponsor: National Heart, Lung, and Blood Institute
Title: C-X-C Chemokines and Kaposi’s Sarcoma
PI: David M. Markovitz
Dates: 7/1/01-5/31/07
Funding Amount: $1,000,000
Sponsor: Arthritis Foundation
Title: Expression of DEK in macrophages: implications for JRA
PI: Nirit Mor-Vaknin
Dates: 7/1/00-6/30/02
Role: Mentor to Dr. Nirit Mor-Vaknin, Postdoctoral Fellow
Funding Amount: $70,000
Sponsor: National Institute of Allergy and Infectious Diseases
Title: Regulation of HIV-2 transcription and replication
PI: David M. Markovitz
Dates: 7/15/98-6/30/2003
Funding Amount: $986,679
Sponsor: Arthritis Foundation
Title: Role of DEK in JRA
PI: David M. Markovitz
Dates: 1/1/01-12/31/03
Funding Amount: $250,000
Sponsor: National Institute of Allergy and Infectious Diseases
Title: C-X-C Chemokines and HIV Pathogenesis
PI: David M. Markovitz
Dates: 9/30/04-4/14/05
Funding Amount: $135,000
Sponsor: University of Michigan Comprehensive Cancer Center Prostate Spore Pilot Project
Title: Role of secreted vimentin in the pathogenesis of prostate cancer
PI: David M. Markovitz
Dates: 6/1/04-5/31/05
Funding Amount: $50,000
Sponsor: MI Institute for Clinical and Health Research
Title: Use of HERV-K (HML-2) as a biomarker for lymphoma and breast cancer
PI: Scott D. Gitlin
Dates: 10/1/07-9/30/08
Role: Co-investigator
Funding Amount (Markovitz): $35,000
Sponsor: Burroughs Wellcome Fund
Title: Clinical Scientist Award in Translational Research
PI: David M. Markovitz
Dates: 1/1/04-12/31/08
Funding Amount: $750,000
Sponsor: UMHS Faculty Group Practice Board of Directors
Title: DEK as a Biomarker in JRA/JIA
PI: Barbara S. Adams
Dates: 9/1/08-8/31/09
Role: Co-investigator
Funding Amount (Markovitz): $11,500
Sponsor: National Institute of Allergy and Infectious Diseases
Title: C-X-C Chemokines and HIV Pathogenesis
PI: David M. Markovitz
Dates: 4/15/05-12/31/09
Funding Amount: $1,115,000
Honors and Awards
1976 University of Minnesota, B.A., Magna Cum Laude
1990 National Cancer Institute - Clinical Investigator Award
1991 Life and Health Insurance Medical Research Fund Scholar
1997 American Society for Clinical Investigation
2003 Burroughs Wellcome Fund Clinical Scientist Award in Translational Research
2004 Association of American Physicians
Memberships in Professional Societies
American Society for Microbiology
American Association for the Advancement of Science
Infectious Diseases Society of America
American Federation for Clinical Research
Central Society for Clinical Research
American Society for Clinical Investigation
Association of American Physicians
Editorial Positions, Boards, and Peer-Review Service
Editorial Board
Journal of Virology
2002-2007
Ad Hoc Reviewer (Journals)
AIDS Research and Human Retroviruses
1992-present
Blood
1993-present
Journal of Clinical Investigation
1994-present
Journal of Biological Chemistry
1995-present
Clinical Infectious Diseases
1994-present
Journal of Virology
1995-present
Journal of Infectious Diseases
1995-present
Proceedings of the National Academy of Sciences, USA
1999-present
Molecular Endocrinology
1999-present
Virology
2002-present
Nature Immunology
2004-present
Molecular and Cellular Biology
2006-present
Cancer Research
2008-present
Journal of Molecular Evolution
2008-present
PLoS Genetics
2009-present
Cancer Research
2009-present
Ad Hoc Reviewer (Grants)
Veterans' Administration Medical Centers
1991-present
National Science Foundation
1994-present
National Institutes of Health
1996-present
Food and Drug Administration
2003-present
Teaching
Clinical Teaching
Instruction of medical students and Infectious Diseases fellows in the outpatient clinic
Instruction of medical students, residents, and Infectious Diseases fellows on Infectious Diseases Consult Service (two months/year)
Undergraduate Students
Laboratory research mentor for Ms. Amruta Mundade, Ms. Anna Tavakkoli, Mr. Nilesh Shah, and Ms. Kim Guo (Dr. Shah is now an Internal Medicine faculty member at UCSD, Ms. Guo is attending the University of Michigan Medical School, Ms. Tavakkoli is attending the University of Florida Medical School, and the late Ms. Mundade was accepted into the University of Michigan Medical School). The current undergraduate students in the laboratory are Anjan Saha, Yue (Anna) Yu, Angie Contreras and Miguel Rivas.
Master’s Students
Ayesha Khan, Department of Epidemiology, School of Public Health, University of Michigan
Amalie Dick, University of Konstanz (Germany)
Medical Students in Laboratory
Pre-clinical advisor and laboratory mentor for Ms. Juliet Mavromatis (Dr. Mavromatis is now an Internal Medicine faculty member at Emory University).
Laboratory research instruction for Ms. Kristin Robinson, medical student, for which she won the AOA Award for Best Research by a Medical Student (Dr. Robinson is now a faculty member at the University of California at Davis).
Laboratory research instruction for Ms. Lisa Bodley (Dr. Sprague [Bodley] is now a pediatrician at IHA Pediatric Healthcare Associates, Canton, MI).
Laboratory research instruction for Mr. Sia Dahi (currently a fourth-year medical student at the University of Michigan)
Laboratory research instruction for Mr. Joseph Wollman (currently a second-year medical student at the University of Michigan)
Ph.D. Preliminary Examination Committees
Sin-Hang Chan, Department of Microbiology and Immunology
Eric Humke, Cellular and Molecular Biology Program
Yifei Wu, Cellular and Molecular Biology Program
Irfan Lodhi, Cellular and Molecular Biology Program
Kelly Seidl, Immunology Program
Vilasack Thammavongsa, Immunology Program
Eric Komuniecki, Immunology Program
Travis Maures, Cellular and Molecular Biology Program
Matthew Pratt-Hyatt, Cellular and Molecular Biology Program
Adam MacNeil, Harvard School of Public Health
Elizabeth Wonderlich, Cellular and Molecular Biology Program
Elisabeth Starnes, Cellular and Molecular Biology Program
Doctoral Thesis Committees
Liqian Zhang, Department of Biological Chemistry
Wei Zhu, Department of Anatomy and Cell Biology
Evelisse Gonzalez, Cellular and Molecular Biology Program
Yifei Wu, Cellular and Molecular Biology Program
Narayani Moorthy, Cellular and Molecular Biology Program
Ping Ye, Department of Microbiology and Immunology
Mojgan Naghavi, Karolinska Institute, Stockholm, Sweden
Jennifer Fuller, Program in Immunology
Jennifer McGregor, Program in Immunology
Tamara Tucker, Cellular and Molecular Biology Program
Ron Merhavi, School of Music
Christoph Carter, Cellular and Molecular Biology Program
Kevin Vannella, Immunology Program
Laboratory Research Instruction for Internal Medicine Residents
Dr. Vivian Lin (now Senior Director of Clinical Affairs at NanoBio)
Dr. William Geisler (now an Assistant Professor of Infectious Diseases at the University of Alabama)
Dr. Emily Wong (now an Infectious Diseases physician)
Dr. Jeffery Anderson (now Clinical Assistant Professor at the University of North Carolina)
Dr. Rajan RaviKumar (now an Assistant Professor of Internal Medicine at the University of Michigan)
Dr. Emily Stoneman (now Infectious Diseases faculty at the University of Michigan)
Post-Doctoral Fellows
Nina Clark, M.D., Infectious Diseases Fellow (now an Assistant Professor of Medicine at the University of Illinois)
John Hilfinger, Ph.D. (now Executive Vice President at TSRL)
Igho Ofotokun, M.D., Infectious Diseases Fellow (now an Assistant Professor of Medicine at Emory University)
Joanne Cleary, Ph.D. (now a scientist in the Department of Obstetrics and Gynecology at the University of Michigan)
Nirit Mor-Vaknin, Ph.D. (now a Research Assistant Professor at the University of Michigan)
Ferdinand Kappes, Ph.D.
Rafael Contreras, Ph.D.
Ph.D. Advisor
Glenn Fu, School of Public Health (Winner of the Third Annual (1994) Prize for Student Research from the Department of Epidemiology); (currently Director of Molecular Biology at Incyte)
Catherine Browning, Department of Microbiology and Immunology (now a medical writer)
Neil Faulkner, Cellular and Molecular Biology Program, Medical Scientist Training Program (currently a Hematologist at Wayne State University)
Brian Lane, Cellular and Molecular Biology Program, Medical Scientist Training Program (won prize for outstanding research by a graduating medical student, 2002); (currently a Urologist with Michigan Medical Professional Corporation (mmpc))
Kajal Sitwala, Cellular and Molecular Biology Program, Medical Scientist Training Program (currently a Hematopathologist at the Marshfield Clinic)
Michael Khodadoust, Immunology Program, Medical Scientist Training Program (currently an Internal Medicine Resident at Stanford University)
Michael Swanson, Immunology Program (currently a Postdoctoral Fellow at the University of North Carolina)
Marta Gonzalez, Immunology Program
Committee, Organizational, and Volunteer Service
Biosafety Level 3 Facility Committee, University of Michigan Medical Center, 1989-presentSearch Committee for Director of Infection Control/Infectious Diseases faculty member, Department of Internal Medicine, 1991Pharmacy and Therapeutics Committee, University of Michigan Hospitals,
1991-1999
Organizing Committee, Advances in Internal Medicine Course, Department of Internal Medicine, Spring of 1989 and 1992Washtenaw County AIDS Task Force, Washtenaw County Michigan, 1993-1994
Virology Search Committee, University of Michigan School of Public Health, 1994-1995Seminar Organizing Committee, Organogenesis Center, 1996-1999
Chair of Seminar Organizing Committee, Organogenesis Center, 1997-1999
Antibiotic Subcommittee, University of Michigan Hospitals, 1996-1999Cellular and Molecular Biology 850 Lecture Series Organizing Committee, 1997-2004Steering Committee, Molecular Mechanisms of Microbial Pathogenesis Training Program, 1998-presentOrganizer, Virology Research Group, 1996-2001
Epidemiology Search Committee, School of Public Health, 2001-2003 Infectious Diseases Faculty Search Committee, 2001-present
University of Michigan Medical School Admissions Committee, 2003-present
Search Committee for Chair, Department of Biological and Material Sciences, University of Michigan Dental School, 2004
Graduate Student Affairs Committee, Program in Immunology, 2007-2010
Consulting Positions
FDA Vaccines and Related Biological Products Advisory Committee
2002-2006
Research Committee, Infectious Diseases Society of America
2009-present
Visiting Professorships, Seminars, and Extramural Invited Presentations
(since 1998)
Regulation of Retroviral Transcription by Cellular Factors Infectious Diseases Seminar SeriesMemorial Sloan-Kettering Cancer Center, New York, New YorkJanuary 1998
Regulation of HIV-2 Transcription Seminar Series, Harvard School of Public HealthFebruary 1998
Regulation of HIV-2 Transcription Co-organizer and SpeakerKeystone Symposium: HIV Pathogenesis and Treatment Park City, UtahMarch 1998
Regulation of HIV-2 Transcription by Intriguing Cellular Factors Molecular Medicine SeriesOregon Health Sciences University, Portland, OregonMay 1998
Regulation of HIV-2 Transcription by Intriguing Cellular Factors Seminar Series, University College, London, EnglandJune 1998
Regulation of HIV-2 Transcription by Intriguing Cellular Factors Molecular and Cellular Biology Seminar, Arizona State UniversityTempe, ArizonaOctober 1998 Regulation of HIV-2 Transcription Department of Virology Seminar SeriesKarolinska Institute, Stockholm, SwedenOctober 1998 HIV-2 Infection University of LisbonLisbon, PortugalOctober 1998
Regulation of HIV-2 Transcription by Cellular Factors Second ICGEB Virology SymposiumNew Delhi, IndiaNovember 1998 Infection with HIV-2 Internal Medicine Grand RoundsUniversity of Illinois at ChicagoDecember 1998
"Regulation of HIV-2 Transcription by Intriguing Cellular Factors"Internal Medicine Research ConferenceTulane UniversityNew Orleans, LouisianaApril 1999"GLI-2 Synergizes with Tat to Activate HIV Transcription"International Symposium on HIV, Leukemia, & Opportunistic CancersMarrakesh, MoroccoMay 1999
Regulation of HIV Transcription by Intriguing Cellular Factors City of Hope Medical CenterDuarte, CaliforniaJuly 1999
Regulation of HIV Replication by Intriguing Cellular Factors University of the Virgin IslandsSt. Thomas, Virgin IslandsFebruary 2000
Regulation of HIV Transcription San Marino Conference on Immunology, Oncology, and VirologyRepublic of San MarinoJune 2000 Regulation of HIV Transcription and Replication New Jersey Medical SchoolNewark, New JerseyOctober 2000 Regulation of HIV by Intriguing Cellular Factors University of California at IrvineIrvine, CaliforniaNovember 2000
The Role of IL-8 and GRO-α in HIV Replication GlaxoSmithKlinePhiladelphia, PennsylvaniaJanuary 2001 IL-8, Gro-α, and Kaposi’s Sarcoma University of Minnesota Dental SchoolMinneapolis, MinnesotaFebruary 2001
HIV and Cellular Factors Harvard School of Public HealthBoston, MassachusettsApril 2001 DEK Expression is Regulated by PP2A Indiana University Cancer Center SymposiumIndianapolis, IndianaApril 2001
Regulation of DEK Expression 4th International Conference on Gene Regulation, Oncogenesis, and AIDSAthens, GreeceSeptember 2002 Regulation of DEK Expression Universit Libre de BruxellesBrussels, BelgiumOctober 2002
Adventures with the Exotic DEK Protein Department of Biochemistry, University of MinnesotaMinneapolis, MinnesotaApril 2003
Adventures with the Exotic DEK Protein
Johns Hopkins Medical School, Department of Molecular Pharmacology
Baltimore, Maryland
September 2003
Regulation of HIV Transcription by Intriguing Cellular Factors
Meeting of the Institute of Human Virology
Baltimore, Maryland
October 2003
Adventures with the Exotic DEK Protein University of Konstanz
Konstanz, Germany
October 2003
AIDS
University of Seville
Seville, Spain
October 2003
The Role of IL-8 and GRO-α in HIV Replication
Department of Pathology, Stanford University
Palo Alto, California
January 2004
Adventures with the Exotic DEK Protein
Laboratory of Dr. Robin Reed, Harvard Medical School
Boston, Massachusetts
February 2004
Regulation of HIV Replication by Cellular Factors
Committee on Microbiology, University of Chicago
Chicago, Illinois
May 2004
The Role of IL-8 and GRO-α in HIV Replication
Meeting of the Institute of Human Virology
Baltimore, Maryland
October 2004
Adventures with the Exotic DEK Protein: in the Footsteps of HMGB1
LIJ Institute for Medical Research
Manhasset, New York
January 2005
IL-8, GRO-, and HIV Replication
North Shore University Hospital
Manhasset, New York
January 2005
The Role of DEK in Inflammation
Pontificia Universidad Cat lica De Puerto Rico
Ponce, Puerto Rico
April 2005
Prosthetic Joint Infections
Texas Tech Health Sciences Center
Lubbock, TX
September 2005
Adventures with the Exotic DEK Protein
Chiron Vaccine Research Center
Siena, Italy
October 2005
The DEK Autoantigen is a Secreted Chemotactic Factor
Eli Lilly and Company
Indianapolis, IN
November 2005
Adventures with DEK
Emory University
Atlanta, GA
March 2006
Exploiting HIV to Dissect Cellular Mechanisms
University of Alabama
Birmingham, AL
June 2006
Adventures with the DEK Autoantigen
University of North Carolina
Chapel Hill, NC
October 2006
The Role of Vimentin in Microbial Pathogenesis
Novartis Vaccines
Siena, Italy
November 2006
Endogenous Retroviruses
bioMerieux Global Research and Development
Grenoble, France
February 2007
Unexpected Chemokines Emerging from Studies of HIV
Weizmann Institute
Rehovot, Israel
June 2007
Adventures at the Interface Between Virus and Cell
University of Miami, Department of Internal Medicine
Miami, Florida
September 2007
The Exotic DEK Protein Modulates Chromatin Structure
Centre de Regulacio Genomica
Barcelona, Spain
October 2007
The Secret Life of the Human Endogenous Retrovirus HERV-K
Karolinska Institute
Stockholm, Sweden
December 2007
The Secret Life of the Human Endogenous Retrovirus HERV-K
University of Wisconsin
Madison, WI
April 2008
The Secret Life of a Human Endogenous Retrovirus
Instituto Scientifico Universitario San Raffaele
Milan, Italy
October 2008
The Human Endogenous Retrovirus HERV-K
Dartmouth-Hitchcock Medical Center
Lebanon, NH
March 2009
The Secret Life of the Endogenous Retrovirus HERV-K
University of Cincinnati
Cincinnati, OH
May 2009
The Secret Life of an Endogenous Retrovirus
Blood Systems Research Institute/UCSF
San Francisco, CA
July 2009
Human Endogenous Retroviruses as Cancer Biomarkers
Ninth Frye Halloran Symposium on Neuro-Oncology
Massachusetts General Hospital
Boston, MA
November 2009
The Secret Life of a Human Endogenous Retrovirus
University of Toledo
Toledo, OH
March 2010
Human Endogeneous Retroviruses and Cancer
Novartis Vaccines
Siena, Italty
June 2010
PATENTS
Methods for Inhibition of HIV Replication Using a Small Molecule Inhibitor
U.S. #7,052,676
Date of Issue: November 3, 2005
Methods of Secretory Vimentin Detection and Modulation
U.S. #7,691,582
Date of Issue: April 6, 2010
Compositions and Methods for Detecting Cancer for Inhibiting Metastasis
U.S. #7,641,902
Date of Issue: January 5, 2010
DEK Protein Compositions and Methods of Using the Same
Application #12/090,164
Converted September 9, 2008
Approval pendingHERV Group II Viruses in Lymphoma and Cancer
Application #12/090,164
Filed September 7, 2007
Approval pending
Antiviral Treatment of Lymphoma and Cancer
#61/180,321
Filed May 21, 2009
Approval pending
Bibliography
Peer-Reviewed Journals and PublicationsMarkovitz, D.M., Beutner, K.R., Maggio, R.P., and Reichman, R.C. Failure of recommended treatment for secondary syphilis. JAMA 1986; 255(13):1767-1768.Gartner, S., Markovits, P., Markovitz, D.M., Kaplan, M.H., Gallo, R.C., and Popovic, M. The role of mononuclear phagocytes in HTLV-III/LAV infection. Science 1986; 233:215-219.
Gartner, S., Markovits, P., Markovitz, D.M., Betts, R.F., and Popovic, M. Virus isolation from and identification of HTLV-III/LAV-producing cells in brain tissue from a patient with AIDS. JAMA 1986; 256(17):2365-2371.Hall, C.B., Dolin, R., Gala, L.C., Markovitz, D.M., Zhang, Y.C., Madore, P.H., Disney, F.A., Talpey, W.B., Green, J.L., Francis, A.B., and Pichichero, M.E. Children with Influenza A infection: treatment with Rimantadine. Pediatrics 1987; 80(2):275-282.Kenney, S., Kamine, J., Markovitz, D.M., Fenrick, R., and Pagano, J.S. An Epstein-Barr virus immediate-early gene product trans-activates gene expression from the human immunodeficiency virus long terminal repeat. Proc. Natl. Acad. Sci. USA 1988; 85:1652-1656.
Kenney, S., Kamine, J., Holley-Guthrie, E., Mar, E.C., Lin, J.C., Markovitz, D., and Pagano, J. The EBV immediate-early gene product, BMLF1, acts in trans by a posttranscriptional mechanism which is reporter gene dependent. J. Virology 1989; 63(9):3870-3877.
Markovitz, D.M., Kenney, S., Kamine, J., Smith, M.S., Davis, M., Huang, E-S., Rosen, C., and Pagano, J.S. Disparate effects of two Herpesvirus immediate-early gene trans-activators on the HIV-1 LTR. Virology 1989; 173:363-367.Markovitz, D.M., Hannibal, M., Perez, V.L., Gauntt, C., Folks, T.M., and Nabel, G.J. Differentia