Quality Control Assistant

Ramya Chari

Temple University School of Medicine

215-***-**** (O) or 267-***-**** (C)

E-mail: abqawq@r.postjobfree.com

URL:http://astro.temple.edu/ cramya

Research Interests

Vascular Biology and Thrombosis

Protein Kinase C s and their implications to thrombosis

Mechanisms of regulated platelet exocytosis

Thrombosis and Cancer

Education

Ph.D, Physiology August 2005 - Present

Temple University, School of Medicine, Philadelphia PA USA

GPA : 3.70/4.00

Major : Physiology

M.Sc., Animal Sciences August 2003 - May 2005

Hyderabad Central University (HCU), Hyderabad, India

GPA : 77.85% (Distinction)

Major : Animal Biotechnology

B.Sc. Food Science and Quality Control August 2000 - May 2003

Osmania University College for Women, Hyderabad, India

GPA : 88.9% (Distinction)

Major : Zoology, Biological Chemistry

Awards and Honors

Pre-doctoral Fellowship (2007-2009) from American Heart Association, Great Rivers A liate.

The 25th Annual Dr. Erwin Margulies Award for Outstanding Scienti c Achievement in Throm-

bosis Research, Temple University, June 2009.

American Society of Hematology (ASH) Travel award, December 2008.

Frank Baldino Travel Award, Temple University School of Medicine, Fall 2007.

Ranked 8th in the All-India entrance exam for Master s conducted by Hyderabad Central Uni-

versity in the year 2003.

Dr. Vanaja Iyengar Cash prize for the Best Student in Sciences for the academic year, awarded

by Osmania University 2002-2003 and 2003-2004.

Rasheeda Patel Rolling Trophy for obtaining highest score in Science, awarded by Osmania

University 2001-2003.

Ameena Pope Cash Prize for the Best Student in Sciences, awarded by Osmania University

2003-2004.

Shireen Shro Cash Prize for the Best Student in General English, awarded by Osmania Uni-

versity 2002-2003.

Professional Memberships

American Heart Association (AHA).

Association of Scientists of Indian Origin in America, Inc. (ASIOA).

Academic and Professional Experience

Research Assistant May 2006 - Present

Temple University School of Medicine

Investigate the molecular mechanisms underlying di erential regulation of platelet dense

granule secretion.

Master s Research May 2003 - Aug 2005

Hyderabad Central University, India

Studied the activation of caspases and calpains at di erent reperfusion time periods in

Bilateral Carotid Artery Occlusion (BCAO) model in rats.

Quality Control Analyst Intern May 2002 - July 2002

Jitender R.F Mills, Hyderabad

Undergraduate project.

Quality Control Analyst Intern May 2001 - July 2001

Modern Food Industries India Limited, Hyderabad

Undergraduate project.

Peer Reviewed Journal Publications

Ramya Chari, Soochong Kim, Swaminathan Murugappan, Archana Sanjay, James L. Daniel and

Satya P. Kunapuli, Lyn, PKC, SHIP-1 interactions regulate GPVI-mediated platelet dense

granule secretion, Blood 2009 Oct 1;114(14):3056-63.

Ramya Chari, Todd Getz, Bela Nagy Jr., Kamala Bhavaraju, Yingying Mao, Yamini Saraswathy

Bynagari, Swaminathan Murugappan, Keiko Nakayama and Satya P. Kunapuli, PKC di er-

entially regulates platelet functional responses, Arterioscler Thromb Vasc Biol. 2009 May;

29(5):699-705.

Swaminathan Murugappan, Ramya Chari, Vasu M. Palli, Jianguo Jin, Satya P. Kunapuli, Dif-

ferential Regulation of Threonine and Tyrosine Phosphorylations on Protein Kinase C by G

protein-mediated pathways in platelets, Biochem J. 2009 Jan 1;417(1):113-20.

Ramya Chari, Yamini Saraswathy Bynagari, Bela Nagy Jr. and Satya P. Kunapuli, Protein

Kinase Cs - implications to thrombosis, submitted to Current Signal Transduction Therapy.

Conference Papers: Oral Presentations

Ramya Chari, Soochong Kim, Swaminathan Murugappan, Archana Sanjay, James L Daniel and

Satya P. Kunapuli (2009). Molecular mechanisms underlying di erential regulation of platelet

dense granule secretion by Protein Kinase C - delta . Arteriosclerosis, Thrombosis and Vascular

Biology (ATVB conference) Abstract # 353.

Ramya Chari, Swaminathan Murugappan, Soochong Kim and Satya P. Kunapuli (2007). Pro-

tein Kinase C-delta di erentially regulates platelet dense granule secretion through the associa-

tion with SHIP-1 . American Society of Hematology in the special session on Basic Science of

Thrombosis and Hemostasis -Platelet Receptors and Signaling. Abstract # 3630.

Conference Papers: Poster Presentations

Ramya Chari, Soochong Kim, Swaminathan Murugappan, Archana Sanjay, James L. Daniel

and Satya P. Kunapuli (2009). Lyn, Protein Kinase C and SHIP-1 negatively regulate GPVI-

mediated dense granule secretion in platelets, International Society on Thrombosis and Hemosta-

sis (ISTH conference), Abstract # 809.

Ramya Chari, Todd Getz, Bela Nagy Jr., Kamala Bhavaraju, Yingying Mao, Yamini Saraswathy

Bynagari, Keiko Nakayama, James L. Daniel and Satya P. Kunapuli (2008). Di erential regula-

tion of platelet functional responses by Protein Kinase C delta . American Society of Hematology

(ASH), Abstract # 1841.

Ramya Chari, Swaminathan Murugappan, Soochong Kim and Satya P. Kunapuli (2007). Pro-

tein Kinase C-delta di erentially regulates platelet dense granule secretion through the associa-

tion with SHIP-1, American Society of Hematology, Abstract # 3630.

Ramya Chari, Sudhakar Reddy K and Prakash Babu P (2004). Apoptosis in degenerative dis-

eases (motor neurons) . International Neuroscience Conference, organized by Indian Academy

of Neurosciences (IAN) and Society for Neurochemistry, India (SNCI).

Teaching Experience

Fall 2009 Advanced Platelet Physiology Course 9821 (0550) Teaching Assistant.

Laboratory Skills

Basic: Platelet isolation, measuring aggregation, secretion, calcium mobilization measurement,

thromboxane A2 ELISA assay, immunoblotting, co-immunoprecipitations, blood draw from mice,

isolation of murine platelets.

Molecular Biology: PCR, primer designing, generating site-directed mutants, isolation of

DNA and plasmid preparation.

Cell culture: Transient and stable transfections.

Histology: Tissue sectioning, para n embedding and Hematoxylin-Eosin staining.

Relevant Coursework

Cell Biology Cellular Pharmacology

Fundamentals of Biochemistry Principles of Physiology

Advanced Platelet Physiology Physiology Seminar

Concepts in Molecular Physiology Physiology of Immune Responses

Physiology Introduction to Biostatistics

Perceptives in Physiology Molecular Signaling

Experimental Physiology

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