Resume of Professor Dr. Zhang-Jie Shi

Curriculum vitae

Zhang-Jie Shi, Ph.D.

Associate Professor Tel: +86-10-627*-****

Department of Chemistry & Fax: +86-10-627*-****

Chemical Engineering

Peking University Email: abqaqe@r.postjobfree.com

202 Chengfu Road Web: http://www.chem.pku.edu.cn/zshi/

Beijing 100871, China

EDUCATION

SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF

SCIENCES: Shanghai, China

Doctor of Philosophy: Organometallic Chemistry

June, 2001

EAST CHINA NORMAL UNIVERSITY: Shanghai, China

Bachelor of Science: Chemistry

July, 1996

RESEARCH EXPERIENCE

ASSOCIATE PROFESSOR: December 2004 to present

Department of Chemistry & Chemical Engineering, Peking University: Beijing, China

RESEARCH FELLOW: March 2003 to September 2004

Department of Chemsitry, The University of Chicago: Chicago, IL 60037, USA

Advisor: Dr. Chuan He

POSTDOCTORAL FELLOW: September 2001 to March 2003

Harvard University: Cambridge, MA 02138, USA

Advisor: Dr. Gregory L. Verdine

GRADUATE RESEARCH ASSISTANT: September 1996 to June 2001

Shanghai institute of Chemistry, Chinese Academy of Sciences: Shanghai, China

Advisor: Dr. Shengming Ma

AWARDS AND FELLOWSHIPS

2008 The First Rank Fok Ying Tung Education Foundation Award

2008 CCS-John Wiley Excellent Chemistry Award

2007 The Second Rank Award of National Natural Sciences

2007 Distinguished Young Chemist Award of Chinese Chemical Society

2006 Synlett/Synthesis Journal Award

2005 The First Rank Award of Science and Technology of Shanghai

2001 President Excellent Award, Chinese Academy of Sciences

1999 Liu Yongling Award, Chinese Academy of Sciences

OTHER SCIENTIFIC ACTIVITIES

Co-founder of, and scientific director for, OKEANOS TECH CO. LTD. (Beijing, China)

Scientific advisor for AVIVA Biosciences Corp. (CA, USA)

Scientific advisor for Air Liquid Laboratory K. K. (ALL) (Wadai, Tsukuba-shi, Ibaraki-Pref.

300-4247, Japan)

PUBLICATIONS

Publications as a PI

1. Direct Benzylic Alkylation via Ni-Catalyzed Selective sp3 C-O Activation. Bing-Tao Guan,

Shi-Kai Xiang, Bi-Qin Wang, Zuo-Peng Sun, Yang Wang, Ke-Qing Zhao, and Zhang-Jie Shi. J.

Am. Chem. Soc. 2008, in press.

2. Methylation of arenes via Ni-catalyzed aryl C O/F activation Bing-Tao Guan, Shi-Kai

Xiang, Tao Wu, Zuo-Peng Sun, Bi-Qin Wang, Ke-Qing Zhao and Zhang-Jie Shi. Chem. Comm.

2008, online. (2008, DOI: 10.1039/b718998b)

3. Recent Advances on Direct Arylation via Palladium Catalyzed Aryl C-H Activation. Bi-Jie

Li, Shang-Dong Yang, Zhang-Jie Shi. Synlett. 2008, in press. (Invited Account).

4. Palladium Catalyzed Direct Arylation of (Hetero)Arenes with Aryl Boronic Acids.

Shang-Dong Yang, Chang-Liang Sun, Zhao Fang, Bi-Jie Li, Yi-Zhou, Li, and Zhang-Jie Shi.

Angew. Chem. Int. Ed. 2008, 47, 1473-1476.

5. Multiple C-H Activations To Construct Biologically Active Molecules in a Process

Completely Free of Organohalogen and Organometallic Components. Bi-Jie Li, Shi-Liang Tian,

Zhao Fang, Zhang-Jie Shi. Angew. Chem. Int. Ed. 2008, 47, 1115-1119. (Hightlighted by

Science, NatureChina, Hot paper of Angew. Chem., Inside Cover of Angew. Chem.)

6. Suzuki-Miyaura Coupling Reaction by PdII-Catalyzed Aromatic C-H Bond Activation

Directed by an N-Alkyl Acetamino Group. Zhangjie Shi, Bijie Li, Xiaobing Wan, Jiang Cheng,

Zhao Fang, Bin Cao, Changming Qin, Yang Wang. Angew. Chem. Int. Ed. 2007, 46(29),

5554-5558. (Hightlighted by NatureChina).

7. Aerobic Oxidation of Alcohol in Aqueous Solution Catalyzed by Gold. Huanrong Li,

Bingtao Guan, Wenjin Wang, Dong Xing, Zhao Fang, Xiaobing Wan, Liping Yang and Zhangjie

Shi, Tetrahedron. 2007, 63(35), 8430-8434. (Invited article).

8. Indirect ortho Functionalization of Substituted Toluenes through ortho Olefination of

N,N-Dimethylbenzylamines Tuned by the Acidity of Reaction Conditions. Guixin Cai, Ye Fu,

Yizhou Li, Xiaobing Wan, and Zhangjie Shi. J. Am. Chem. Soc. 2007, 129, 7666-7673.

9. Ortho Arylation of Acetanilides via Pd(II)-Catalyzed C-H Functionalization. Shangdong

Yang, Bijie Li, Xiaobing Wan, and Zhangjie Shi. J. Am. Chem. Soc., 2007, 129, 6066 -6067.

(One of the hot papers).

10. Multiple deprotonations and deaminations of phenethylamines. An Unprecedented Apporach

to Synthesize Pyrroles. Xiaobing Wan, Dong Xing, Zhao Fang, Bijie Li, Fei Zhao, Keyan Zhang,

Liping Yang, and Zhangjie Shi. J. Am. Chem. Soc. 2006, 128, 120**-*****.

11. Highly Selective C-H Functionalization/Halogenation of Acetanilide. Xiaobing Wan,

Zhongxun Ma, Bijie Li, Keya Zhang, Shaokui Cao, Shiwei Zhang and Zhangjie Shi. J. Am. Chem.

Soc. 2006, 128, 7176-7177.

12. Gold(I)-Catalyzed Oxidative Cleavage of a C-C Double Bond in Water. Dong, Xing; Bingtao

Guan, Guixin Cai, Zhao Fang, Liping Yang, Zhangjie Shi. Org. Lett. 2006, 6, 693-696. (One of

the hot papers).

13. Highly Selective Aerobic Oxidation of Alcohol Catalyzed by Gold(I) Complex with Anionic

Ligand. Bingtao Guan, Dong Xing, Guixing Cai, Xiaobin Wan, Nan Yu, Zhao Fang, Liping

Yang and Zhangjie Shi. J. Am. Chem. Soc. 2005, 127, 180**-*****.

Other Publications

14. Intramolecular Additions of Alcohols and Carboxylic Acids to Inert Olefins Catalyzed by

Silver(I) Triflate. Caiguang Yang, Nick W. Reich, Zhangjie Shi, Chuan He. Org. Lett. 2005, 7,

4553-4556.

15. Addition of heterocycles to electron deficient olefins and alkynes catalyzed by gold(III).

Zigang Li, Zhangjie Shi and Chuan He. J. Organomet. Chem. 2005, 690, 5049-5054.

16. Direct Functionalization of Arenes by Primary Alcohol Sulfonate Esters Catalyzed by

Gold(III). Zhangjie Shi and Chuan He. J. Am. Chem. Soc. 2004, 126, 135**-*****.

17. Efficient Functionalization of Aromatic C H Bonds catalyzed by Gold(III) under Mild and

Solvent Free Conditions. Zhangjie Shi and Chuan He. J. Org. Chem. 2004, 69, 3669-3671

18. An Au-catalyzed cycloalkylation of electron-rich arenes with epoxides to prepare

3-chromanols. Zhangjie Shi and Chuan He. J. Am. Chem. Soc. 2004, 126, 5964-5965.

19. An Efficient Synthesis of 4-Halo-5-hydroxyfuran-2(5H)-ones via the Sequential

Halolactonization and -Hydroxylation of 4-Aryl-2,3-alkadienoic Acids. Ma, Shengming*; Wu,

Bin; Shi, Zhangjie. J. Org. Chem. 2004, 69, 1429-1431.

20. Unpredictable stereochemical preferences for mu opioid receptor activity in an exhaustively

stereodiversified library of 1,4-enediols. Zhangjie Shi, Bryce A. Harrison, and Gregory L.

Verdine. Org. Lett., 2002, 5, 633-636.

21. Extensively Stereodiversified Scaffolds for Use in Diversity Oriented Library Synthesis.

Tiffany Malinky Gierasch, Zhangjie Shi, Gregory L. Verdine. Org. Lett.. 2002, 5, 633-636.

22. Mechanistic switch leading to highly efficient chirality transfer in Pd (0)-catalyzed

coupling-cyclization of aryl iodides with 1:1 acid-base salts of 2, 3-allenoic acids and l- -cinchonidine or d- -/l- - -methylbenzylamine. Enantioselective synthesis of highly optically

active 3-aryl polysubstituted butenolides. Ma, Shengming; Shi, Zhangjie. Chem. Comm. 2002,

(5), 540-541.

23. Synthesis of 4-halo-2(5H)-furanones and their Suzuki-coupling reactions with organoboronic

acids. A general route to 4-aryl-2(5H)-furanones. Ma, Shengming; Shi, Zhangjie. Chin. J.

Chem. 2001, 19, 1280-1284.

14. Enantioselective synthesis of -arylbutenolides via palladium(0) catalyzed asymmetric

coupling cyclization reaction of racemic allenic carboxylic acids with aryl iodides. Ma,

Shengming; Shi, Zhangjie; Wu, Shulin. Tetrahedron: Asymmetry, 2001, 12, 193-195.

25. Palladium(0)-catalyzed cyclization reaction of polymer-supported aryl iodides with

1,2-allenyl carboxylic acids. A facile solid-phase synthesis of butenolides. Ma, Shengming;

Duan, Dehui; Shi, Zhangjie. Org. Lett. 2000, 2, 1419-1422.

26. Synthesis of -halobutenolides and their Pd(0)-catalyzed cross-coupling reactions with

terminal alkynes and organozinc reagents. A general route to -substituted butenolides and

formal synthesis of cis-whisky lactone. Ma, Shengming; Shi, Zhangjie; Yu, Zhanqian.

Tetrahedron 1999, 55, 121**-*****.

27. Synthesis of -halobutenolides and their Pd(0)/CuI-catalyzed cross-coupling reactions with

terminal alkynes. A general route to -(1-alkynyl)butenolides. Ma, Shengming; Shi, Zhangjie;

Yu, Zhanqian. Tetrahedron Lett. 1999, 40, 2393-2396.

28. Pd(0)/Ag+-Cocatalyzed Cyclization Reaction of 1,2-Allenic Carboxylic Acids with

Aryl/Alkenyl Halides. An Efficient Synthesis of Butenolides. Ma, Shengming; Shi, Zhangjie. J.

Org. Chem. 1998, 63, 6387-6389.

29. Efficient Synthesis of 4-Halo-4-penten-2-ones and 3-Halo-3-butenoic Acids/Esters via

Hydrohalogenation Reaction of 3,4-Pentadien-2-one and 2,3-Butadienoic Acid/Methyl Ester.

Ma, Shengming; Shi, Zhangjie; Li, Lintao. J. Org. Chem. 1998, 63, 4522-4523.

INVITED LECTURES

1. The 3nd International Forum on Homogeneous Catalysis and The First China-Spain

Bilateral Symposium on Catalysis, Shanghai, China, Sept. 23-27, 2008. (Accepted).

2. ICOMC23 and France-China workshop, Rennes, France, Jul. 13-18, 2008. (Accepted).

3. Kyushu University-Department of Chemistry, Fukuoka, Japan, Mar. 18-21. (Accepted).

4. Fujian Institute of Research on the Struture of Matter, Chinese Academy of Sciences,

Fuzhou, China, Dec. 28, 2007

5. Beijing Normal University-Department of Chemistry, Beijing, 100875, China, Oct. 25,

2007.

4th Sino-Japanese Symposium on Organic Chemistry for Young Scientists, Narita, Japan,

6.

Sept. 22-26, 2007.

7. The University of Wisconsin, Madison - Chemistry Department (Madison, WI, USA), Sept.

6, 2007.

8. CAOSS Symposium in Purdue University (West Lafayette, IN, USA), Aug. 31, 2007.

9. The University of Chicago - Chemistry Department (Chicago, IL, USA), Aug. 28, 2007.

10. Harvard University - Department of Chemistry and Chemical Biology (Cambridge, MA,

USA), Aug. 17, 2007.

11. Joint Workshop on Chemistry and Material among PKU, ICCAS and NTU (Taiwan) April

25-May 1, 2007;

12. CSIR-NSFC Joint Workshop on Organic Chemistry and Chemical Biology: Bridging Bonds

for 21st Century (Plenary Lecture, Pune, India), April 11-13, 2007;

9th International Symposium for Chinese Organic Chemists (ISCOC-9, Singapore),

13.

December 17-21, 2006;

14th National Conference of Organometallic Chemistry (Suzhou, Jiansu, China), October

14.

19-23, 2006;

1st Sino-German Symposium Frontiers of Chemistry (Kloster Seeon, Germany), July 19-23,

15.

2006;

25th Chinese Chemical Society Meeting (25th CCS, Changchun, Jilin, China); July 10-14,

16.

2006;

17. East China Normal University-Shanghai Key Institute of Green Chemistry (Shanghai,

China); April 24, 2006;

1st Symposium on Green Chemistry by Green Chemistry Centre (Beijing, China), April 26,

18.

2006;

19. Sino-German Symposium on Organocatalysis and Certain Aspects of Green Chemistry

(Hangzhou, China); April 2-6, 2006;

20. Chemistry Today-Peking University, College of Chemistry and Chemical Engineering

(Bejing, China); March 31, 2006;

2nd Symposium of Beijing National Lab (Beijing, China), January 10, 2006;

21.

22. University of Science and Technology of China-College of Chemistry (Hefei, Anhui,

China), December 3, 2005.

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