Development Medical
Resume:
Shubha Tole
Department of Biological Sciences
Tata Institute of Fundamental Research
Mumbai-400,005, India
email: **********@*****.***
Current Appointment:
Associate Professor Department of Biological Sciences 2007
Tata Institute of Fundamental Research, India -present
Visiting Associate Professor Stanford University 2008-2009
Previous Appointments:
Tata Institute of Fundamental Research, India 2002-2007
Reader
Tata Institute of Fundamental Research, India 1999-2002
Fellow
Post Doctoral Fellow University of Chicago 1994-1999
Education:
Ph D California Institute of Technology 1994
MS California Institute of Technology 1991
BSc St. Xavier's College, University of Bombay 1987
Awards and Grants:
1. The S. S. Bhatnagar Award in Biological Sciences 2010
This award is given by the CSIR and is considered to be India s highest scientific honor
2. Research Award for Innovation in Neuroscience (RAIN award) 2008
Society for Neuroscience
3. Wellcome Trust Flexible Travel Award 2008-2009
For a Sabbatical year at Stanford University, USA
4. National Woman Bioscientist award 2008
Dept. Biotechnology, Govt. of India
5. Rapid Grant for Young Investigators 2008-2011
Dept. Biotechnology, Govt. of India
6. The Swarnajayanti Fellowship (Govt. of India) 2005-2010
India s Golden Jubilee award for young scientists
7. Research Grant (Dept. Biotechnology, Govt. of India) 2006-2009
8. Research Grant (Dept. Science and Technology, Govt. of India) 2006-2009
9. The Wellcome Trust Senior Research Fellowship 1999-2006
10. AMBO International Training Fellowship 2000
11. Scholarship Award 1995, '97, '99
Women's Council of the Brain Research Foundation, Chicago
12. Postdoctoral Fellowship 1996, 1997
Committee on Cancer Biology, University of Chicago
1
13. International Fellowship 1996
American Association of University Women
Memberships:
Member, International Affairs Committee, American Society for Cell Biology 2009- present
Board Member, Indian Society of Developmental Biologists 2000-present
Society for Neuroscience, USA 1991-present
Current Lab members:
Post Doctoral Fellows: Dr. Ramya Ghai
Dr. M. Bhavana
PhD students:
Anindita Sarkar
Achira Roy
Integrated PhD students:
Dhananjay Huilgol
Ashwin Shetty
Post Doctoral researchers supervised in previous years (came from; current position)
Dr. Nandini Gokulchandran (MD-Nagpur Medical College;
Research Scientist, SRL Ranbaxy, Mumbai)
Dr. Vishakha Mangale (PhD- NIRR, Mumbai; Research Scientist, GE Healthcare, Banglore)
Dr. Alfredo Socorro (PhD- ULL, Spain; Post doc with Gundela Meyer, ULL, Spain)
Dr. Ben Martynoga (PhD- U. Edinburgh, UK;
Post doc with Francois Guillemot, MRC, UK)
Students Graduated from the Tole lab (current position)
PhD: Bhaskar Saha (PhD 2006; postdoc with Alain Chedotal, CNRS, France)
PhD: Padmanabhan Hari (PhD 2008; postdoc with Jeff Macklis, Harvard Medical School)
PhD: Lakshmi Subramanian (PhD 2008; postdoc with Arnold Kreigstein, UCSF)
MSc:
Dhananjay Chaturvedi (MSc 2008; PhD student at U. Texas, Dallas)
R.V. Satyaki (MSc 2007; PhD student in Cornell University)
Aditi Falnikar (MSc 2006; PhD student in Drexel University)
Mugdha Deshpande (MSc 2006; PhD student in U. Texas, Austin)
Ryan Remedios (MSc 2005; PhD student in MPI, Tuebingen)
Vanisha Lakhina (MSc 2004; PhD student in University of Pennsylvania)
Lakshmi Subramanian (MSc 2004; PhD 2008, TIFR; currently post doc at UCSF)
Aditee Vyas (MSc 2002; PhD 2006, IGBMC, France
Currently Research Scientist at Nicholas Piramal, Mumbai)
Sarada Bulchand (MSc 2002; PhD student in TLL, Singapore)
2
Publications
1) Tole S. and Vale, R. (2010). Young leaders for Biology in India. Science 329: 1441. (Editorial)
2) Subramanian L, and Tole S. (2009) Mechanisms underlying the specification, positional regulation and function of the
cortical hem. Cerebral Cortex 19 (Suppl 1):i90-5.
3) Subramanian L, Remedios, R, Shetty, AS, and Tole S. (2009) Signals from the Edges: The Cortical Hem and Antihem
in telencephalic development. Seminars in Cell and Developmental Biology 20(6):712-8
4) Mangale VS*, Hirokawa KE*, Satyaki PRV*, Gokulchandran N*, Chikbire S, Subramanian L, Shetty,AS, Martynoga B,
Paul J, Mai MV, Li Y, Flanagan LA, Tole S#, and Monuki ES # (2008) Lhx2 selector activity specifies cortical identity
and suppresses hippocampal organizer fate Science 319: 304-309
# co- corresponding authors
5) Hari P, Deshpande M, Sharma N, Rajyadhaksha N, Ramkumar N, Kimura, K., Rodrigues V#, Tole S#. (2008) Chip is
required for post-eclosion behaviour in Drosophila. J. Neuroscience 28:9145-50.
# co- corresponding authors
6) Barry G, Piper M, Lindwall C, Moldrich R, Mason S, Little E, Sarkar A, Tole S, Gronostajski RM, Richards LJ. (2008)
Specific glial populations regulate hippocampal morphogenesis. J Neuroscience. (28):12328-40.
7) Remedios, R., Huilgol., D., Saha, B., Hari, P., Bhatnagar, L., Ohshima, T., Stoykova, A., Tole S. (2007) A novel stream
of amygdaloid cells from the caudal telencephalon reveals a developmental link between the amygdala and the
neocortex Nature Neuroscience (10) 1141 1150
8) Lakhina, V., Falnikar, A., Bhatnagar, L., Tole, S. (2007) Early thalamocortical tract guidance and topographic sorting of
thalamic projections requires LIM- homeodomain gene Lhx2 Developmental Biology (306) 703-713
9) Saha, B. Hari P., Huilgol, D. and Tole, S. (2007) Dual role for LIM-HD gene Lhx2 in the formation of the lateral olfactory
tract (LOT) J. Neuroscience (27) 2290-2297
10) Tole S#, Gutin G., Bhatnagar, L., Remedios, R, Hebert, J# (2006) Development of midline cell types and commissural
axon tracts requires Fgfr1 in the cerebrum. Developmental Biology, 289: 141 151
# co- corresponding authors
11) Tole S#, Remedios R, Saha B, Stoykova A # (2005) Differential roles of Pax6 and Emx2 in the development of the
amygdaloid complex. J. Neuroscience, 25(10):2753 2760.
# co- corresponding authors
12) 11) Remedios, R., Subramanian, L., Tole S. (2004) LIM genes parcellate the embryonic amygdala and regulate its
development. J. Neuroscience, 24(31):6986-6990.
13) Vyas, A., Saha, B., Lai, E., Tole, S. (2003) The Paleocortex is specified in mice in which dorsal telencephalic patterning
is severely disrupted. Journal of Comparative Neurology, 466:545-553
14) Bulchand, S., Subramanian, L., and Tole, S. (2003) Dynamic spatio-temporal expression of LIM genes and co-factors in
the embryonic and postnatal cerebral cortex. Developmental Dynamics, 226(3):460-469.
15) Bansal, R#, Lakhina, V., Remedios R., Tole, S# (2003) Expression of FGF Receptors 1, 2, and 3 in the Embryonic And
Postnatal Mouse Brain: Implications for Oligodendrocyte Development. Developmental Neuroscience, 25: 83-95.
# co- corresponding authors
16) Bulchand, S., Grove, E. A., Porter, F. D., and Tole, S. (2001). LIM-homeodomain gene Lhx2 regulates the formation of
the cortical hem. Mechanisms of Development, 100(2) 165-175.
3
Contact this candidate