CUNLAN GUO Curriculum Vitae

Address: *** ******* ** *** **, West Lafayette, IN, 47906

Cell phone: 765-***-****; E-Mail Address: abpa0u@r.postjobfree.com or abpa0u@r.postjobfree.com

EDUCATION:

Ph.D. in Chemistry 2009

Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, China

Advisor: Dr. Zhuang Li,

B. S. in Chemistry 2004

Department of Chemistry, Zhengzhou University, China

RESEARCH INTERESTS:

(1) AFM studies of biomacromolecules behaviors on the interface, including the adsorption and self-assembly of

biomacromolecules on liquid/solid interface;

(2) Raman spectrum, including mechanism and application in biomacromolecules detection;

(3) Synthesis of metal fluorescence clusters and their application in detection;

(4) Functionalization of metal nanoparticles, and their applications in biological detection;

(5) DNA methylation detection and DNA methylation related proteins.

RESEARCH EXPERIENCE:

Postdoctoral Research Fellow, Department of Agricultural & Biological Engineering, Purdue University, West

Lafayette, IN, USA 2010.02-

Collaborator: Dr. Joseph Irudayaraj

(1) Synthesized a novel fluorescent silver cluster via protein-directed approach and its applications in mercury (II)

ion detection.

(2) Improved the properties of graphene oxide through modification with different molecules; studied their effects on

mammalian cell.

(3) Functionalized gold nanoparticles with Raman tag and protein for DNA methylation detection.

Research Assistant, State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied

Chemistry, Chinese Academy of Sciences, China 2004-2009

Advisor: Dr. Zhuang Li

(1) Prepared the surface relevant regulable DNA toroids; studied the behavior of DNA-dopamine complex in solution

and on the liquid-solid interface.

(2) Researched the low temperature induced disassembly of the filaments consisting of DNA and RecA recombinase

on the mica surface.

(3) Investigated the influence of cationic polyelectrolyte (i.e., poly-L-lysine) on the filaments formation of RecA

1

recombinase on the DNA to understand the reaction mechanism.

(4) Constructed a hydrogen peroxide biosensor by immobilizing HRP in room temperature ionic liquid doped DNA

network.

INSTRUMENTS AND TECHNIQUES:

Instruments: Atomic force microscopy (imaging under air or in liquid; Veeco Nanoscope IIIa and Bio-Scope AFM,

Asylum Research 3-D AFM), Confocal Raman microscopy (Renishaw 2000, Bruker), Fluorescence spectroscopy,

UV-vis spectroscopy, circular dichroism spectroscopy, Various electrochemistry methods, Gel electrophoresis, SEM,

TEM;

Techniques: Cell culture (mammalian), Gold Nanoparticles synthesis and modification, synthesis of Au and Ag

clusters, graphene oxide fabrication by chemical method.

PUBLICATIONS

1. Cunlan Guo, Joseph Irudayaraj*, Synthesis of fluorescent Ag clusters and their application in Hg(II) ion

detection, Anal. Chem., submission.

2. Cunlan Guo, Gaiping Li, Zhelin Liu, Lanlan Sun, Yujing Sun, Fugang Xu, Yue Zhang, Tao Yang, and Zhuang Li*,

Influence of Polyelectrolyte on DNA-RecA Nucleoprotein Filaments: Poly-L-Lysine Used as a Model,

ChemPhysChem, 2009, 10, 1624-1629.

3. Cunlan Guo, Zhelin Liu, Fugang Xu, Lanlan Sun, Yujing Sun, Tao Yang, and Zhuang Li*, Surface Relevant

Regulable DNA Toroids Induced by Dopamine, J. Phys. Chem. B, 2009, 113, 6068-6073.

4. Cunlan Guo, Yonghai Song, Li Wang, Lanlan Sun, Yujing Sun, Chongyang Peng, Zhelin Liu, Tao Yang, and

Zhuang Li*, Atomic force microscopic study of low temperature induced disassembly of RecA-dsDNA filaments,

J. Phys. Chem. B, 2008, 112, 1022-1027.

5. Cunlan Guo, Yonghai Song, Hui Wei, Peicai Li, Li Wang, Lanlan Sun, Yujing Sun, and Zhuang Li*, Room

temperature ionic liquid doped DNA network immobilized horseradish peroxidase biosensor for amperometric

determination of hydrogen peroxide, Anal. Bioanal. Chem., 2007, 389, 527-532.

6. Yonghai Song, Cunlan Guo, LanlanSun, Gang Wei, Chongyang Peng, Li Wang, Yujing Sun, and Zhuang Li*,

Effects of bridge ions, DNA species, and developing temperature on flat-lying DNA monolayers, J. Phys. Chem.

B, 2007 111, 461-468.

7. Zhelin Liu, Bo Zhao, Cunlan Guo, Yujing Sun, Fugang Xu, Haibin Yang, Zhuang Li*, Novel Hybrid

Electrocatalyst with Enhanced Performance in Alkaline Media: Hollow Au/Pd Core/Shell Nanostructures with a

Raspberry Surface, J. Phys. Chem. C, 2009, 113, 167**-*****.

8. Li Wang, Gang Wei, Cunlan Guo, Lanlan Sun, Yujing Sun, Yonghai Song, Tao Yang, and Zhuang Li*,

Photochemical synthesis and self-assembly of gold nanoparticles, Colloids Surf., A, 2008, 312, 148-153.

9. Yujing Sun, Lanlan Sun, Fugang Xu, Cunlan Guo, Zhelin Liu, Tao Yang, and Zhuang Li*, Electrodeposition of

Platinum Nanoclusters on Type I Collagen Modified Electrode and its Electrocatalytic Activity for Methanol

2

Oxidation, Appl. Surf. Sci. 2009, 255, 6814-6818.

10. Lanlan Sun, Yonghai Song, Li Wang, Cunlan Guo, Yujing Sun, Zhelin Liu, and Zhuang Li*, Ethanol-induced

formation of silver nanoparticle aggregates for highly active SERS substrates and application in DNA detection,

J. Phys. Chem. C, 2008, 112, 1415-1422.

11. Xiaohua Liu, Lixue Zhang, Yuling Wang, Cunlan Guo, and Erkang Wang, Biomimetic crystallization of unusual

macroporous calcium carbonate spherules in the presence of phosphatidylglycerol vesicles, Cryst. Growth

Des., 2008, 8, 759-762.

12. Yujing Sun, Li Wang, Lanlan Sun, Cunlan Guo, Tao Yang, Zhelin Liu, Fugang Xu, and Zhuang Li*, Fabrication,

characterization, and application in surface-enhanced Raman spectrum of assembled type-I collagen-silver

nanoparticle multilayered films, J. Chem. Phys., 2008, 128, 074704-1-6.

13. Lanlan Sun, Li Wang, Yonghai Song, Cunlan Guo, Yujing Sun, Chongyang Peng, Zhelin Liu, and Zhuang Li*,

Aggregation-based growth of silver nanowires at room temperature, Appl. Surf. Sci., 2008, 254, 2581-2587.

14. Li Wang, Yonghai Song, Lanlan Sun, Cunlan Guo, Yujing Sun, and Zhuang Li*, Controllable synthesis of gold

nanowires, Mater. Lett., 2008, 62, 4124-4126.

15. Tao Yang, Zhuang Li*, Li Wang, Cunlan Guo, and Yujing Sun, Synthesis, characterization, and self-assembly of

protein lysozyme monolayer-stabilized gold nanoparticles, Langmuir, 2007, 23, 105**-*****.

16. Lanlan Sun, Yonghai Song, Li Wang, Yujing Sun, Cunlan Guo, Zhelin Liu, and Zhuang Li*, DNA-Templated

Gold Nanoparticles Formation, J. Nanosci. Nanotechno., 2008, 8, 4415-4423.

17. Li Wang, Bin Qi, Lanlan Sun, Yujing Sun, Cunlan Guo, and Zhuang Li*, Synthesis and assembly of Au-Pt

bimetallic nanoparticles, Mater. Lett., 2008, 62, 1279-1282.

18. Lanlan Sun, Gang Wei, Yonghai Song, Li Wang, Cunlan Guo, Yujing Sun, and Zhuang Li*, Controlled

organization of silver nanoparticles into network assemblies by tuning pH values, Chem. Lett., 2007, 36,

610-611.

19. Lanlan Sun, Yonghai Song, Gang Wei, Li Wang, Cunlan Guo, Yujing Sun, and Zhuang Li*, Self-assembled gold

nanoparticle chains in presence of silver ions, Chem. Lett., 2007, 36, 142-143.

20. Yujing Sun, Lanlan Sun, Baohua Zhang, Fugang Xu, Zhelin Liu, Cunlan Guo, Yue Zhang, Zhuang Li*, Type I

collagen-mediated synthesis of noble metallic nanopartilces networks and the applications in surface-enhanced

raman scattering and electrochemistry, Talanta, 2009, 79, 562-569.

21. Lanlan Sun, Yujing Sun, Fugang Xu, Yue Zhang, Tao Yang, Cunlan Guo, Zhelin Liu, and Zhuang Li*, Atomic

force microscopic and surface-enhanced Raman scattering detection of DNA based on DNA-nanoparticle

complexes, Nanotechnology, 2009, 20, 125502.

22. Yujing Sun, Gang Wei, Yonghai Song, Li Wang, Lanlan Sun, Cunlan Guo, Tao Yang, and Zhuang Li*, Type I

collagen-templated assembly of silver nanoparticles and their application in surface-enhanced Raman scattering,

Nanotechnology, 2008, 19, 115604-1-8.

23. Gang Wei, Li Wang, Lanlan Sun, Yonghai Song, Yujing Sun, Cunlan Guo, Tao Yang, and Zhuang Li*, Type I

3

collagen-mediated synthesis and assembly of UV-photoreduced gold nanoparticles and their application in

surface-enhanced Raman scattering, J. Phys. Chem. C, 2007, 111, 1976-1982.

24. Yonghai Song, Zhuang Li*, Zhiguo Liu, Gang Wei, Li Wang, Lanlan Sun, Cunlan Guo, Yujing Sun, and Tao

Yang, A novel strategy to construct a flat-lying DNA monolayer on a mica surface, J. Phys. Chem. B, 2006, 110,

107**-*****.

25. Li Wang, Gang Wei, Lanlan Sun, Zhiguo Liu, Yonghai Song, Tao Yang, Yujing Sun, Cunlan Guo, and Zhuang

Li*, Self-assembly of cinnamic acid-capped gold nanoparticles, Nanotechnology, 2006, 17, 2907-2912.

CONFERENCE PROCEEDINGS:

1. Cunlan Guo, Zhuang Li*, Tao Yang, Yujing Sun, Lanlan Sun, and Li Wang, Atomic force microscopic study of

low temperature induced disassembly of RecA-dsDNA filaments, The 11th International and the 1st Sino-Japan

Bilateral Symposium on Electroanalytical Chemistry, Changchun, China. August, 2007, 46.

2. Cunlan Guo, Yonghai Song, Hui Wei, Peicai Li, Li Wang, Lanlan Sun, Yujing Sun, Tao Yang, Erkang Wang, and

Zhuang Li*, Room temperature ionic liquid doped DNA network immobilized horseradish peroxidase biosensor

for amperometric determination of hydrogen peroxide, The 11th International and the 1st Sino-Japan Bilateral

Symposium on Electroanalytical Chemistry, Changchun, China, August, 2007, 217-218.

4

REFERENCES:

Professor Zhuang Li

Deputy Head of State Key Laboratory of Electroanalytical Chemistry

Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, P.R. China.

Tel: +86-431-********, E-mail: abpa0u@r.postjobfree.com;

Professor Erkang Wang

Academician of the Chinese Academy of Sciences, Academician of the Third World Academy of Sciences

Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, P.R. China.

Tel: +86-431-********, E-mail: abpa0u@r.postjobfree.com;

Professor Hongda Wang

Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, P. R. China.

Tel: +86-431-********, E-mail: abpa0u@r.postjobfree.com.

Professor Joseph Irudayaraj

Agricultural & Biological Engineering, Purdue University

Tel: 765-***-****, E-mail: abpa0u@r.postjobfree.com;

5

Contact this candidate