Project Assistant

Edward Tutu

Email: *********@********.***

Address: 5425B Ponderosa Street

City: Columbia

State: MO

Zip: 65201

Country: USA

Phone: 979-***-****

Skill Level: Experienced

Salary Range: $2,000

Willing to Relocate

Primary Skills/Experience:

See Resume

Educational Background:

See Resume

Job History / Details:

EDWARD TUTU

5425 B Ponderosa St., Columbia, MO 65201

979-***-**** *********@********.***

ANALYTICAL SCIENTIST WITH EMPHASIS IN RESEARCH AND DEVELOPMENT

Analytical Scientist with diverse research experience in separation science, with emphasis on HPLC and CE techniques. Have developed and validated methods for assay of APIs and drug products. Proficient in LC-MS (Ion-trap, SQ, TOF) and GC with FID/MS detection techniques. Highly experienced in use, maintenance and troubleshooting of analytical instrumentation. Adept in protection and deprotection synthetic reaction schemes and preparative-scale synthetic chemistry. Skilled in use of high field 1D and 2D NMR spectroscopy. Member of American Chemical Society and Phi Kappa Phi Honor Society. Recipient of John C. Cothran Memorial Fellowship Award, University of Minnesota, 2002-2003. Received company-wide recognition for completion of a high-priority project within a critical timeline for a client.

CORE COMPETENCIES

Chemical Research and Analysis ~ Project Management ~ Knowledge of cGMP/ICH/FDA guidance ~ Leadership Capabilities ~ Method Development and Validation ~ Analytical Instrumentation ~ Preparative LC ~ IC ~ GC ~ AA ~ ICP ~ FTIR ~ XRF ~ UV-VIS ~ NMR Spectroscopy ~ Capillary Electrophoresis (CE) ~ WinLab32 ~ Mass Lynx ~ Chemstation ~ Empower 2 ~ XCalibur ~ Chemical Inventory Management

PROFESSIONAL EXPERIENCE

Analytical Bio-Chemistry Laboratories, Inc., Columbia, MO

Staff Scientist 2010 - Present

* Design, plan, and implement experimental work in the laboratory for assigned projects.

* Review scientific literature to identify and apply appropriate analytical techniques for a project study.

* Prioritize and complete multiple research and development projects.

* Carry out project studies and document data in a timely manner according to cGMP guidelines.

* Perform method feasibility, development, validation and transfer of CMC biopharmaceutical methods.

* Developed and validated methods for assay and impurities determination of APIs using LC-MS.

* Perform characterization or elucidation of trace level impurities/isolated degraded API samples using NMR and LC-MS.

* Developed methods for analysis of genotoxic impurities using LC-MS and GC-MS.

* Developed and validated method for quantification of trace level metals by ICP-MS and Flame-AA

* Lead projects, train scientists, and collaborate with members of other departments.

* Perform peer review of analytical data for accuracy and completeness.

* Develop and review standard operating procedures, standard test methods, and analytical study protocols.

* Perform raw materials testing according to USP/EP Compendia, cGMPs and regulatory guidelines.

* Receive hands-on experience with SEM/EDAX, DSC/TGA and KF.

Texas A&M University Department of Chemistry, College Station, TX

Research Assistant 2004 - 2010

* Synthesized cyclodextrin-based chiral resolving agents using protection and deprotection synthetic schemes.

* Developed HPLC/ELSD, HPLC/UV, and LC-MS methods for monitoring and evaluating purity of synthetic products.

* Characterized synthetic products using 1D- and 2D-NMR and MALDI-TOF-MS.

* Developed CE methods for determination of pKa of carrier ampholytes and analysis of chiral drugs.

University of Minnesota Department of Chemistry, Duluth, MN

Research Assistant 2001 - 2003

* Synthesized novel compound, 4-(2- methylbutylamino)pyridine-2,6-dicarboxylic acid.

* Characterized the novel compound using 1D NMR and GC-MS.

* Performed Circularly Polarized Luminescence spectroscopic studies of compounds.

EDUCATION

Ph.D., Analytical Chemistry, 2010

Texas A&M University, College Station, TX

Master of Science, Chemistry, 2003

University of Minnesota, Duluth, MN

Bachelor of Science, Chemistry, 1998

University of Cape Coast, Cape Coast, Ghana

SELECT PUBLICATIONS

-Synthesis, analytical characterization and initial capillary electrophoretic use in an acidic background electrolyte of a new, single-isomer chiral resolving agent: Heptakis(2-O-sulfo-3-O-methyl-6-O-acetyl)--cyclodextrin- Edward Tutu, Gyula Vigh, Electrophoresis, Special Issue: Enantioseparations, 32, 2655 (2011)

-Synthesis and characterization of quaternary ammonium dicarboxylic isoelectric buffer and their use in pH-biased isoelectric trapping separations.- Sanjiv Lalwani, Edward Tutu, G. Vigh, Electrophoresis, 26, 2047 (2005)

-Isoelectric buffers, Part 3: Determination of pKa and pI values of diamino sulfates carrier ampholytes by indirect UV-detection capillary electrophoresis.- Sanjiv Lalwani, Edward Tutu, G. Vigh, Electrophoresis, 26, 2503 (2005)

SELECT PRESENTATIONS

35th International Symposium on High Performance Liquid Phase Separations and Related Techniques, June 19-24, 2010, Boston, MA. -Synthesis of Heptakis-2-O-sulfo-cyclomaltoheptataose, A single-isomer chiral resolving agent for enantiomer separations in capillary electrophoresis.-

18th International Symposium on MicroScale Bioseparations, February 12-17, 2005, New Orleans, LA. -MOSES: Materials for Optimized Systems of Electrophoretic Separations.-

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