Medical Project
Resume:
Linda MacArthur
Email: *********@********.***
Address: **** ****** *****
City: Fairfax
State: VA
Zip: 22031
Country: USA
Phone: 703-***-****
Skill Level: Experienced
Salary Range: $80,000
Primary Skills/Experience:
See Resume
Educational Background:
See Resume
Job History / Details:
Linda MacArthur
ADDRESS
Georgetown University Medical Center
Department of Neuroscience
3900 Reservoir Road, N.W., NRB Rm. WP-24A
Washington, D.C. 20007
Ph: 202-***-****
********@**********.***
Program development and management with emphasis on multi-disciplinary partnerships to solve complex health problems. Areas of specialization in neuroscience, trauma, and immunology with a focus on biomarker discovery for diagnosis and prognosis of neuroimmune disorders.
COMPETENCIES
* Systems for Biomarker Discovery
* Medical Education and Program Development
* Regulatory Awareness-animal and human
* Team Science-strategic planning and multi-site project management
* Oral and written communication
* Scientific collaboration with government and military
RECENT SKILLS AND ACCOMPLISHMENTS
* Hired to assist with a two year project delay involving collection of blood from subjects with a suspected traumatic brain injury. The goal of the grant is to identify blood based biomarkers useful for diagnosing brain injury. The delay was caused by problems with collaborative agreements and regulatory approvals.
* Within 10 months, material transfer agreements signed, protocols approved, sample collection from research subjects started, and profiling of other samples from related projects started for high throughput data collection. Responsible for regulatory compliance (NIH, DOD), progress reports, Human Subjects Protocols, and coordinating teams at multiple research sites. Responsible for setting up subcontracts for profiling samples, data analysis and preparation of data for publication.
* Interim Director of Biorepository Laboratory-set up procedures for banking materials from new collaborations. Responsible for developing collaborations and coordinating teams for blood profiling, bioinformatics, and statistical analysis.
* Course Co-Director for Special Masters in Physiology Introduction to Neuroscience Course- One of three directors responsible for course development, faculty participation, lectures, and administration.
EDUCATION AND TRAINING
1977-1980 Syracuse University, Syracuse, NY, B.S. Department of Biology
1983-1985 Virginia Commonwealth University, Richmond, VA, M.S. Dept. of Biology
1985-1989 Medical College of Virginia, Richmond, VA, Ph.D. Dept. of Microbiology/ Immunology
RESEARCH EXPERIENCE
Biography
Linda MacArthur earned her Ph.D. in Microbiology and Immunology from the Medical College of Virginia. Following a post-doctoral fellowship at the National institutes of Health where she examined mechanisms regulating the synthesis of analgesis peptides in the adrenal gland, she joined the Department of Neuroscience at Georgetown University as a Research Assistant Professor. She is currently a co-director of the Special Masters in Physiology Introduction to Neuroscience Course, which prepares students to be competitive in Medical School. Her research has focused on the interaction of the nervous and immune systems during homeostasis, in response to injury, and more recently in neurodegeneration. Her previous studies described a mechanism for nervous system feedback on nociceptive neurons to restore homeostasis during chronic inflammation. She has further shown that remodeling of the CNS after injury is improved after a second injury and is associated with changes in immune response that are more favorable to recovery. Ongoing studies are examining a novel mechanism for how the nervous system detects infection, which may have implications for chronic pain. Other studies seek to identify antecedent biomarkers of neuropathic pain in rodents. She currently works as a project coordinator on several multisite studies to discover blood based biomarkers to diagnose and prognose individuals with a suspected traumatic brain injury and to diagnose dementia before the onset of symptoms. These collaborations require strategic planning and multi-site project management, awareness of regulatory requirements, and developing partnerships with other academic institutions, the government, and the military.
1989-1993 Post Doctoral Fellow-Laboratory for Cell Biology, National Institute of Mental Health, Bethesda, MD, 20892.
Responsibilities-research on opioid gene regulation-4 papers and 2 review articles related to subject, 3 papers related to tumor biology.
1993-1997 Staff Fellow, Pain and Neurosensory Mechanisms Branch, National Institute of Dental Research, Bethesda, MD 20892.
Responsibilities-research on regulation of endogenous opioid systems-2 papers related to subject.
1998-2011 Research Assistant Professor,
Dept. of Neuroscience, Georgetown University Medical Center, Washington, D.C. 20007
Responsibilities-research on recovery of function after spinal cord injury. Drug discovery to treat neuropathic pain-5 papers related to spinal cord injury, 2 related to drug discovery for neuropathic pain, 2 others-HIV and peripheral nervous system, nicotinic receptors.
2011-present Project Coordinator, Research Assistant Professor, Dept. of Neuroscience, Georgetown University Medical Center, Washington, D.C. 20007.
Responsibilities-write human subject protocols and obtain IRB approval for studies related to traumatic brain injury and Alzheimer's Disease, coordinate research and data analysis teams at multiple study sites, implement high throughput profiling of research samples, maintain regulatory compliance, write progress reports, maintain budgets, supervise biorepository and laboratory staff (2 full time and 3 part time employees), assist with blood collection and banking, assist with manuscript preparation-first author on 1 book chapter on Systems Medicine.
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