Title:Joseph P Hornak

abp1m5@r.postjobfree.com

Document

Source below

CURRICULUM VITAE

Name: Joseph P. Hornak

Ph.D.

Work Address: Rochester Institute of Technology (RIT)

Center for Imaging Science

54 Lomb Memorial Drive

Rochester, NY 14623-5604 USA

Telephone: Office: 585-***-****

Mobile: 585-***-****

FAX: 585-***-****

E-mail: abp1m5@r.postjobfree.com

Web Address: http://www.cis.rit.edu/people/faculty/hornak/

AREAS OF SPECIALIZATION

Magnetic Resonance (NMR & ESR) - imaging, spectroscopy, spin relaxation, and hardware

Imaging Science - classification, segmentation, and imaging system analysis

Physical Chemistry - quantum mechanics and kinetics

Analytical Chemistry - spectroscopy and scientific instrumentation

Scientific Publishing - web and hardcopy

EDUCATION

B.S

. (Honors) Chemistry Utica College of Syracuse University, Utica, NY

M.S

. Physical Chemistry Purdue University, W. Lafayette, IN

Ph.D

. Chemistry University of Notre Dame, Notre Dame, IN

Post Doc. ESR Spectroscopy Cornell University,

Ithaca, NY

WORK EXPERIENCE

Current Appointments:

1993

-Present Professor with Tenure, Departments of Chemistry, Materials Science &

Engineering,

and Imaging Science, RIT, Rochester, NY

1992

-PresentAdjunct Associate Professor, Radiology Department, University of Rochester

(UR

)

Medical School, Rochester, NY

2000

-PresentPrincipal Investigator, New York State Center for Electronic Imaging

Systems,

Rochester, NY

Previous Appointments:

2009

Guest Professor, Henan Univeristy, Kaifend, Henan, China

2005

Guest Researcher, Leibniz Institut fur Polymerforschung, Dresden, Germany

2001

Visiting Professor, Consiglo Nazionale delle Ricerche (CNR) - Centro per la Medicina

Nucleare, Universita degli Studi di Napoli - Federico II, Naples, Italy

1999

-2003Advisory Board, Imaging Science Initiative, Pacific NW National Laboratory,

Pasco, WA

1997

-2002Editor-in-Chief, Encyclopedia of Imaging Science and Technology, John Wiley &

Sons,

Hoboken, NJ

1991

-1993Associate Professor of Imaging Science and Materials Science, RIT

1990, 1992Visiting Professor, Radiology Department, University of Birmingham,

Birmingham, AL

1989

-1991Wiedman Professor of Imaging Science, RIT, Rochester, NY

1988

-1993Associate Professor, Chemistry Department, RIT, Rochester, NY

1985

-1982Visiting/Adjunct Assistant Professor, Biophysics Department, UR, Rochester, NY

1985

Visiting Scientist, Department of Chemistry, Cornell University, Ithaca, NY

1984

-1988Assistant Professor, Chemistry Department, RIT, Rochester, NY

1982

-1984Post Doctoral Associate, Chemistry Department, Cornell University, Ithaca, NY

CV of Joseph P. Hornak, Ph.D. Page 1 of 20

1978

-1982Graduate Research Assistant, Chemistry Department, University of Notre Dame,

South

Bend, IN

Honors, Awards, and Recognitions

1.

Dean's Summer Research Fellow, 1985, 1987, and 1988, RIT College of Science

.

2.

Wiedman Professor of Medical Imaging, 1989-1991, RIT Center

for Imaging Science.

3. Member of Rochester Chapter of Sigma Xi,

1985

-Present.

4. Honor Society of Phi Kappa Phi, 1990-Present.

5. Invited Keynote Speaker, Annual Meeting of The American Association for Clinical

Chemistry,

Anaheim, CA, July 1995.

6.

Editor-in-Chief

of the John Wiley & Sons, Inc. Encyclopedia of Imaging Science and

Technology,

New York, NY, 1997-2002.

7. Royal Society of Chemistry's Choice Award for The Basics of NMR, 1999.

8. Advanced Chemistry Development Labs Star Pick Educators Award for the hypertext book

The

Basics of NMR, July 2000.

9. Association of American Publishers Professional and Scholarly Award for Multivolume

Science

Reference work: The Encyclopedia of Imaging Science and Technology, 2002.

10. Invited Plenary lecture at the GIDRM XXXVI Italian National Congress on NMR, Vietri

sul Mare,

Salerno, Italy, September 2006.

nd

11. Google Rating of 2 in 21,000,000 for Magnetic Resonance Imaging, The Basics of MRI,

2007.

nd

12. Google Rating of 2 in 25,100,100 for Nuclear Magnetic Resonance, The Basics of NMR,

2007.

13. Invited Keynote Speaker at the meeting of the CT/MRI Society of the American College

of

Veterinary Medicine, Chicago, IL, November 2007.

14. RIT Trustees Faculty Scholarship Award, 2010.

TEACHING EXPERIENCE

Courses Developed at

RIT:

1. Basics of Pulsed NMR (1014-740) - A one credit hour graduate course designed to

introduce the

basics of pulsed or Fourier Transform NMR spectroscopy, including basic pulse sequences,

experimental techniques, and physical and spectral measurements. The course provides

students

with an understanding of the workings and theory of a modern day NMR spectrometer when a

spectrum is acquired. The course also serves as an introduction to other advanced

magnetic

resonance courses such as Magnetic Resonance Imaging (1014-730) and Principles of

Magnetic

Resonance (1014-747).

2. Magnetic Resonance Imaging (1014-730) - An introduction to the principles of magnetic

resonance imaging (MRI). The course covers spin physics, Fourier transforms, basic

imaging

principles, Fourier imaging, imaging hardware, imaging techniques, image processing,

image

artifacts, safety and advanced imaging techniques.

3. Building Scientific Apparatus Lecture (1008-620) - Basic skills associated with the

construction of

scientific laboratory apparatus, some of which is not commercially available are covered:

machine

shop skills, working with glass, vacuum technology, optics and electronics. Special

emphasis on

function-structure relationship between an instrument and its intended use. Several

references on

construction techniques are provided, and information about current manufacturers and

suppliers

of necessary components is given.

4. Building Scientific Apparatus Laboratory (1018-621) - Basic skills associated with the

construction

of scientific laboratory apparatus, some of which is not commercially available, are

covered:

machine shop skills, working with glass, vacuum line technology, optical spectrometer

design and

instrument electronics.

Undergraduate Courses Taught at

RIT:

1. General Chemistry Lecture and Laboratory, Department of Chemistry

2. Scientific Glassblowing, Department of Chemistry

CV of Joseph P. Hornak, Ph.D. Page 2 of 20

3. Undergraduate Chemical Research, Department of Chemistry

4. Instrumental Methods of Analysis Lecture and Laboratory, Department of Chemistry

5. Spectroscopy, Department of Chemistry

6. Quantum Mechanics Laboratory, Department of Chemistry

7. Kinetics Lecture and Laboratory, Department of Chemistry

8. Chemical Separations Laboratory, Department of Chemistry

9. Technical Communication & Research Practices,

Imaging Science Department

10. Senior Research, Imaging Science Department

11. Magnetic Resonance Imaging, Medical Science Department

Graduate Courses Taught at

RIT:

1. Instrumental Methods of Analysis Lecture and Laboratory, Department of Chemistry

2. Magnetic Resonance Imaging, Department of Chemistry and Imaging Science

3. The Basics of Pulsed NMR, Department of Chemistry

4. Principals of Magnetic Resonance, Departments of Chemistry and Imaging Science

5. Graduate Research, Department of Chemistry

6. Graduate Research, Imaging Science Department

Other Teaching Experience:

1. General Chemistry Laboratory, Mohawk Valley Community College, Utica, NY.

2.

General Chemistry Laboratory and Recitation, Purdue University, West Lafayette, IN.

CONSULTING

1.

VirtuaScopics, Inc

. Pittsford, NY, MRI Quality Control.

2.

INVIVO Corp

., Gainesville, FL, Phantom Filler Material.

3. Biophan Technologies, Inc

., Henrietta, NY, MRI Compatible Devices.

4. Eastman Kodak Company, Rochester, NY, MRI of Materials.

5. ConverTec Corporation, Newtown, PA. Non destructive testing apparatus.

6. ChevronTexaco, TX, NMR Trace Analysis of Organics in Sea Water.

7. Bausch & Lomb, Rochester, NY, Magnetic Resonance Imaging of Materials.

8. Coudert Brothers, New York, NY, Technical Advice on MRI Litigation.

9.

Critical Solutions International, Inc

., Dallas, TX, Nuclear Quadruple Resonance.

10. Teradyne, Inc

., North Reading, MA, MRI Hardware.

RESEARCH INTERESTS

1. Sub-Surface MRI

Millions of dollars are lost annually due to utility strikes during construction related

excavation.

Ground penetrating radar (GPR) is the most widely used geophysical imaging tool to locate

buried

utilities, however, its performance in high water content, high conductivity soils is

limited.

Magnetic resonance imaging (MRI) may hold promise as a near-surface imaging modality in

those

conditions where GPR fails. An MRI based technique would produce images of voids from

buried

anthropogenic objects in a signal rich background from water in the soil. We are

experimenting

with various methods for unilateral MRI. One method, called the rastered projection

method, has

been used to build a 1/30 scale prototype. We are also studying the NMR signal from

various

synthetic and natural sands to predict the magnetic resonance signal from fully hydrated

soils.

[See publications: 34, 35, 37, 38, 39, 41]

2. MRI Phantoms and Quality Control

Phantoms are anthropogenic objects used to test the performance of an MRI system.

Phantoms

are filled with an NMR signal bearing material. In phantoms used to measure the

homogeneity of

the B and RF magnetic fields in imagers, these materials must have a controllable spin-

lattice

o

relaxation rate (R ), spin-spin relaxation rate (R ), dielectric constant (e), and

electrical resistivity

12r . The R and R values must be short to acquire images rapidly. A single chemical shift

r12

component is necessary to be able to distinguish quadrature artifacts from chemical shift

artifacts.

A low e is necessary to minimize the standing wave artifact found on higher field MRI

systems.

r

CV of Joseph P. Hornak, Ph.D. Page 3 of 20

The moderate resistivity is necessary to load the RF coil as would the human body. Many

of these

traits are not often found in one substance. The utility of AOT-water-decane reverse

micelle

solutions as a phantom filler material has been demonstrated. This material has the added

benefit

of having chemical shift components in the spectrum similar to that of fat and water in

the human

body. We have also proposed new polymeric materials with one chemical shift component for

these filler materials. We have also developed a resolution phantoms which can be used to

measure the point spread-function, linearity, and resolution of an MRI system at multiple

locations

in a three-dimensional space without the need to reposition the phantom. [See

publications: 18,

27, 28, 40]

3. Targeted MRI Contrast Agents

Targeted contrast agents are molecules or complexes that change their relaxivity on

exposure to

another substance. A gadodiamide solution was determined to be a targeted contrast agent

for

+2 + -1 -1 +

Cu, changing its relaxivity of 4080 in the absence of Cu to 12030 s M in the presence of

Cu .

We are currently investigating the sensitivity of this contrast agent to other metal

ions.

4. Multispectral tissue classification and segmentation using R, R,, d, and PCA

1 2

Several studies were undertaken to determine if normal tissues and pathology could be

identified

and segmented in magnetic resonance images using calculated spin-lattice relaxation rate

(R ),

1

spin-spin relaxation rate (R ), spin density, and chemical sift (d) images. Normal

tissues of the

2

brain could easily be segmented with calculated R, R, and images. Some breast

pathology

1 2

could be identified with the same images. Muscle, adipose tissue, and bone could be

readily

identified and segmented with chemical shift imaging (d). Principal component analysis

(PCA)

proved to be another viable way for segmenting normal tissues of the brain.

[See publications: 19, 21, 22, 23, 26, 29, 30]

5. High-Efficiency Transmit and Receive RF Coils for MRI of Extremities.

The single-turn solenoid (STS), a class of transmit and receive magnetic resonance

imaging coil

was developed for imaging extremities on clinical and specimens on research MRI systems.

STS

coils were developed for imaging a finger, hand, wrist, forearm, shoulder, head,

breast(s),

testicles, knee, ankle, and foot. The STS produces images with a very favorable signal-to-

noise

ratio with a fraction of the power necessary for other coils. One design called the

asymmetric STS

is capable of creating a 90 degree RF pulse with only 130 mW compared to hundreds of

Watts

needed from other coils. [See publications: 9, 10, 11, 13, 14, 15, 25]

6. Magnetic Resonance Imaging of Materials.

MRI has been used extensively in medicine but to a lesser extent for the study of

materials. We

are exploring new applications of MRI in Materials Science and Engineering. [See

publication: 36]

FELLOWSHIPS AND GRANTS

Support Received:

1. 1.5T MRI Imaging Time, UR Medical Center and Ide Radiology, 1985-1989, 200 Hours,

Value

$100,000.

2. Teaching MRI Using Computer Animation. RIT Productivity Grant, 1987-1988, $11,690.

3. Modeling of RF Magnetic Fields in MRI Resonators. IBM RSP, 1988-1989, $26,900.

4. Development of Low Field ESR Spectroscopy as an Analytical Technique. RIT College of

Science

Project Initiation Grant, 1989, $5,300.

5. 200 MHz NMR Spectrometer. Eastman Kodak Company, 1989, valued at $200,000.

6. Teaching NMR Using Computer Animation. RIT Productivity Grant, 1989-1990, $17,000.

7.

T- Correlations in MR Breast Images. University of Rochester Magnetic Resonance

Center, GE

1

Signa Magnetic Resonance Imaging Time, 1990-1991,

$5,400.

8.

NMR Imaging of Gelatin. Eastman Kodak Company, 1990,

$500.

9. NMR Computer Instrumentation.

Eastman Kodak Company, 1990-1991, $30,000.

CV of Joseph P. Hornak, Ph.D. Page 4 of 20

10. Volume Rendering Algorithms for the Hippocampus. University of Rochester Radiology

Dept.,

1990-1991, $12,000.

11. ESR Imaging without DC Magnetic Field Gradients. NSF, 1991-1992, $44,419.

12. The Value of MRI and the Use of Gd Contrast in Pre-Operative Evaluation of Patients

with Partial

Epilepsy. (M.J. Berg, P.I.) University of Rochester, 1991-1992, $17,000.

13. Purchase of a Data System Upgrade for an NMR Spectrometer. NSF, 1991-1992, $27,333.

14. NMR and ESR Studies of Diffusion in Gelatin.

Eastman Kodak Company, 1991-1992,

$10,000.

15. Multispectral Tissue Classification of Brain Pathology. RIT COS PI Grant, 1992,

$5000.

16. Computer Based Teaching Package on MRI. RIT Productivity Grant, 1993-1994, $15,000.

17. MRI Phantom Design. General Electric Medical Systems, 1993-1994, $29,000.

18. Physical & Chemical Properties of Macromolecules, (T. Gennett, P.I.) NSF REU, 1995-

1997,

$149,500.

19. Use of FT NMR in the Undergraduate Chemistry Laboratory, NSF, 1995-1997, $100,000;

RIT

match, $200,000.

20. Imaging of Water in Photographic Paper.

Eastman Kodak Company, 1997-1999,

$4,000.

21. 1.5T MRI Imaging Time,

UR Medical Center and University Medical Imaging, 1990-1999,

400

Hours, Value $200,000.

22. Imaging the NMR Signal from Water in Topsoil, Vermeer Mfg. Co., 2000-2001, $190,320.

23. NMR Detection of Low Concentrations of Oil-in-Water, Chevron, 2001, $6,000.

24. Tissue Classification using R, R, and Images, Consiglio Nazionale delle Ricerche

(CNR)

1 2

International Short Term Mobility Program, and Centro di Medicina Nucleare, Universitr

degli

Studi di Napoli Fererico II, May-June 2001, L25,000,000.

25. Subsurface MRI for Locating Utilities, NYSTAR, 2001-2002, $5,000.

26. US ARMY Red Team, Critical Solutions International, 2002, $6,033.

T MRI Imaging Time, UR Medical Center and University Medical

Imaging,

2000-2008, 20 Hours, Value $20,000.

PUBLICATIONS

of Joseph P. Hornak

Ph.D. Page 6 of 20

4. L.M. Fletcher and J.P. Hornak, "Multispectral Image Segmentation in Magnetic Resonance

Imaging," in Digital Image Processing Methods, E. Dougherty, ed., Marcel Dekker, NY 1994.

5. J.P. Hornak, "Medical Imaging Technology," Kirk-Othmer Encyclopedia of Chemical

Technology,

John Wiley & Sons, Inc. 16:107-134 (1995).

6. J.P. Hornak, "Medical Imaging Technology," Kirk-Othmer Concise Encyclopedia of

Chemical

Technology, Fourth Edition, John Wiley & Sons, Inc., 1263-1265 (1999).

7. J.P. Hornak, "Nuclear Magnetic Resonance Imaging," Methods in Materials Research, ed.

by

Elton N. Kaufmann, John Wiley & Sons, Inc. (2001).

8. J.P. Hornak, Image Formation, Encyclopedia of Imaging Science, John Wiley & Sons,

Inc., 571-

574 (2002).

CV

of Joseph P. Hornak

Ph.D. Page 7 of 20

9. J.P. Hornak, RF Magnetic Field Mapping, Encyclopedia of Imaging Science, John Wiley

& Sons,

Inc., 1223-1227 (2002).

10. A.P. Bak, J.P. Hornak, N.C. Schaller, From Impractical to Practical: Solving an MRI

Problem Using

Parallelism, Advancing Computing and Information Sciences, RIT Cary Graphic Arts Press,

2005.

11. B.J. Antalek, W. Windig, J.P. Hornak; Multivariate Image Analysis of Magnetic

Resonance

Images: component resolution with the Direct Exponential Curve Resolution Algorithm

(DECRA).

Techniques and Applications of Hyperspectral Image Analysis, ed. by H.F. Grahn and P.

Geladi,

Wiley, 2007.

Hardcopy and Hypertext Books:

1. The Basics of NMR Imaging, A Computer Based Educational Package, RIT, 1985.

2. The Basics of NMR Spectroscopy, A Computer Based Educational Package, RIT, 1990.

3. The Basics of MRI, J.P. Hornak, (http://www.cis.rit.edu/htbooks/mri/), Interactive

Learning

Software, 1996

-2009.

4. The Basics of NMR, J.P. Hornak, (http://www.cis.rit.edu/htbooks/nmr/), Interactive

Learning

Software,

1997

-2009.

5. The Encyclopedia of Imaging Science and Technology, J.P. Hornak, Editor-in-Chief, John

Wiley &

Sons, Inc., 2002.

6. The Encyclopedia of Imaging Science and Technology, (Online Version), J.P. Hornak,

Editor-in-

Chief, http://www.mrw.interscience.wiley.com/eist/index.html, John Wiley & Sons, Inc.,

2002.

Applications Notes (not peer-reviewed):

1. J.P. Hornak, R.G. Bryant, Radio Frequency Homogeneity, Texas A. & M. University NMR

Newsletter, 350:40 (Nov. 1987).

2. J.P. Hornak, Advances in technology to focus on targeted care, Rochester Business

Journal, p23,

July 14, 2006.

3. J.P. Hornak, MRI Hardware: A two decade retrospective. Stan s Library, Ed. S.Sykora,

Vol.II. 25

July 2007, (http://www.ebyte.it/library/hist/).

Patents Received:

1. Resonators for Magnetic Resonance Imaging, #5,024,229 and #5,139,024, R.G. Bryant,

J.P.

Hornak, E.A. Marshall, and the University of Rochester, 1991.

2. Resonator for Magnetic Resonance Imaging, #5,542,424, J.P. Hornak, S.D. Szeglowski,

and

Rochester Institute of Technology, 1996.

Continuing Medical Education Articles:

1. Fundamentals of MRI, Part I: Introduction, CE Source, Enterprises for Continuing

Education,

4(2):1-8, Spring 2004. (1 CEU)

2. Fundamentals of MRI, Part II: Spin Physics, CE Source, Enterprises for Continuing

Education,

4(3): 23-31, Summer 2004. (1 CEU)

3. Fundamentals of MRI, Part

III:

NMR Spectroscopy and Fourier Transform, CE Source,

Enterprises

for Continuing Education, 5(1): 15-23, Spring 2005. (1 CEU)

4. Fundamentals of MRI, Part IV: Imaging Principles, CE Source, Enterprises for

Continuing

Education, 5(2): 9-18, Summer 2005. (1 CEU)

5. Fundamentals of MRI, Part V: Basic Imaging Techniques, CE Source, Enterprises for

Continuing

Education, 5(4):11-20, Winter 2005. (1 CEU)

6. Fundamentals of MRI, Part VI: Imaging Hardware, CE Source, Enterprises for Continuing

Education, 6(1): 1-9, Spring 2006. (1 CEU)

7. Fundamentals of MRI, Part

VII:

Image Artifacts, CE Source, Enterprises for Continuing

Education,

6(2): 29-38, Summer 2006. (1 CEU)

8. Fundamentals of MRI, Part

VIII:

Advanced Imaging Techniques, CE Source, Enterprises

for

Continuing Education, 7(1): 8-19, Spring 2007. (1 CEU)

9. Fundamentals of MRI, Part IX: Advanced Imaging Techniques, CE Source, Enterprises for

Continuing Education, 7(2): 1-9, Fall 2007. (1 CEU)

of Joseph P. Hornak

Ph.D. Page 8 of 20

of Joseph P. Hornak

Ph.D. Page 9 of 20

of Joseph P. Hornak

Ph.D. Page 10 of 20

of Joseph P. Hornak

Ph.D. Page 11 of 20

of Joseph P. Hornak

Ph.D. Page 12 of 20

90. K. Baum, M. Helguera, J. Hornak, J. Kerekes, E. Montag, M. Unlu, D. Feiglin, A. Krol,

Techniques

for Fusion of Multimodal Images: Application to Breast Imaging, International Conference

on

Image Processing, Atlanta, GA, October 2006.

th

91. C.L. Bray, J.P. Hornak, Surface Variations in B : Implications for Near Surface MRI,

20

Earth

SAGEEP, Denver, CO, April 2007.

th

92. C.L. Bray, J.P. Hornak, Underground Variations in B : Implications for Near Surface

MRI, 48

Earth

Experimental NMR Conference, Daytona Beach, FL, April 2007.

+2

93. J.P. Hornak, B.C. Lipchick, The relaxivity of Gd-(DTPA-BMA) / Cu mixtures and

evidence for a

Gd-(DTPA-BMA)-Cu complex, Upstate NMR Symposium, Syracuse, NY, October 2007.

94. J.P. Hornak, MRI: Where we are at and where we are going, Invited Talk, American

College of

Veterinary Radiology Annual Scientific Meeting, Chicago, IL, November 2007.

95. C.L. Bray, M.J. Cox, J.P. Hornak, G. Ferrante, R.G. Bryant, Y. Goddard, and S. Sur, R

of

1

th

Hydrated Sands as a Function of Magnetic Field, 49 Experimental NMR Conference, Asilomar,

CA March 2008.

+2

96. B.C. Lipchick, M. Monahan, J.P. Hornak, An Interaction of Gadodiamide with Cu,

Rochester

ACS Harrison Howe Poster Session, Rochester, NY, March 2008.

97. J.P. Hornak, C.L. Bray, R.G. Bryant, M.J. Cox, G. Ferrante, Y. Goddard, S. Sur, The

NMR Spin

Lattice Relaxation Rate of Hydrated Sands as a Function of Magnetic Field, SAGEEP,

Philadelphia, PA, April, 2008.

+2

98. B.C. Lipchick, M. Monahan, J.P. Hornak, An Interaction of Gadodiamide with Cu,

Rochester

ACS Undergraduate Research Symposium, Geneseo, NY, April, 2008.

+2 +2 th

99. J.P. Hornak, B.C. Lipchick, M. Monahan, An Interaction of Gadodiamide with Cu and Zn, 16

ISMRM, Toronto

Contact this candidate