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Curriculum Vitae
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Contents
1 Personal
2 Education
3 Postdoctoral Training
4 Academic Appointments
5 Awards
6 Professional Affiliations
7 Areas of Research Interest
8 Currently Active Projects
9 Teaching Activities
9.1 Classroom, Seminar or Teaching Laboratory
9.2 Major Invited Lectureships
10 Other Professional Activities
11 University, State and National Committees
11.1 University
11.2 State
11.3 National
12 Financial Resources (Grants and Contracts)
12.1 Currently Active
Personal
Citizenship: United States
Birthplace: Angola, Indiana
Contact Information: Department of Biology
115 Thomas Hunt Morgan Building
University of Kentucky
Lexington, KY 40506
*******.******@***.***
Education
Precollege: Sturgis High School, Sturgis, Michigan, 1970
College: Amherst College, Amherst, Massachusetts
B.A. Biology, 1974
Graduate: Michigan State University, East Lansing, MI.
M.S. Physiology, 1976
Thesis Title: Control of Renin Secretion: Effect of d-Propranolol and Renal Denervation
on Furosemide Induced Renin Secretion in the Dog.
Michigan State University, East Lansing, MI.
Ph.D. Physiology, 1979.
Dissertation Title: Immaturity of Renal Function in Newborn Pigs: Factors Affecting Renal
Hemodynamics, Sodium Excretion and Plasma Renin Activity. Michael D. Bailie, M.D., Ph.D.,
Advisor.
Postdoctoral Training
Postdoctoral Research Fellow, 1979-1981. Department of Internal Medicine and
Cardiovascular Research Center, University of Iowa.
Gerald F. DiBona, M.D., Advisor.
Academic Appointments
2010 Present Professor and Associate-Chair Education
Department of Biology
University of Kentucky
2003 2010 Professor
Department of Biology
University of Kentucky
1999 - 2003 Director
Greater Hartford Academy of Mathematics and Science
The Learning Corridor
Hartford, CT
1999 2003 Adjunct Professor of Biology and Neuroscience Program
Trinity College
Hartford, CT
1988 - 1999 Associate Professor of Physiology
The Medical College of Wisconsin
Milwaukee, Wisconsin
1992 1999 Director
MCW Center for Science Education
The Medical College of Wisconsin
Milwaukee, Wisconsin
1997 Visiting Sr. Scientist
Department of Pediatrics
Karolinska Institute
Stockholm, Sweden
Anita C. Aperia, M.D., Ph.D (Host)
Professor of Pediatrics
1981 1988 Assistant Professor of Physiology
The Medical College of Wisconsin
Milwaukee, Wisconsin
Awards
National Research Service Award. Cardiovascular Training Center, University of Iowa, Iowa
City, 1979.
Kidney Foundation of Iowa, Research Fellowship, 1979.
Established Investigator of the American Heart Association, 1987-1992.
American Society of Hypertension Young Investigator Award, Finalist, 1990.
President's Award for Distinction in Research, American Heart Association/WI Affiliate,
1994.
Great Teacher Award, University of Kentucky Alumni Association 2006-2007
Arthur Guyton Teacher of the Year Award, American Physiological Society 2007
Professional Affiliations
1979-Present American Physiological Society
2003-Present National Association of Biology Teachers
2004-Present Association of Science Teacher Education (ASTE)
1979-1999 American Society of Nephrology
1979-1999 International Society of Nephrology
1979-1989 American Federation for Clinical Research
1981-1995 Society for Experimental Biology and Medicine
1982-1999 American Heart Association - Council on Basic Science
1982-1999 American Heart Association - Council on Kidney in Cardiovascular Disease
1987-1999 American Heart Association - Council on High Blood Pressure
1988-1999 American Heart Association/Wisconsin Affiliate
1991-1996 American Society of Hypertension
Areas of Research Interest
Effective Models of Teaching Mathematics and Science Among Urban, Suburban and Rural K-12
Students; Role of Professional Development in Student Achievement in the Science
Classroom; Regulation of Arterial Pressure: Neural Control of Renal Function; Genetic
Factors in Neurogenic Hypertension
Currently Active Projects
Assessing How Distance Learning for Teachers Can Enable Inquiry Science in Rural
Classrooms; Recruiting, Retaining and Graduating Appalachian and Minority Students in
STEM; Louis Stokes Alliance for Minority Participation: Recruitment and Retention of
Minority Students into STEM Majors
Genetic Determinants of Hypertension in a Congenic Spontaneously Hypertensive Rat Model
Teaching Activities
Classroom, Seminar or Teaching Laboratory
Year Level Course Hours
1978 201 Introductory Physiology(MSU) 4
1981-1999 Grad Medical Physiology (MCW) 81981-1999 Grad Advanced Renal Physiology (MCW) 5
1999-2003 Pre-College Pathophysiology & Pharmacology (GHAMAS) 5
2000-2003 Pre-College Experimental Research (GHAMAS) 5
2001-2003 Collegiate General Endocrinology(Trinity) 4
2002-2003 Collegiate Methods of Neuroscience(Trinity) 4
2003 Grad Inquiry Based Science Teaching for Middle 3
and High School Teachers (UConn)
2003-Present Grad Teaching High School Biology with Inquiry-UK 3
2004, 2010 Collegiate Biology 350 - Animal Physiology (UK) 2/4
2010-Present Collegiate Biology 350 Animal Physiology 4
2004-Present Collegiate Biology 550 Comparative Physiology (UK) 3
2004-2007 Collegiate Discovery Seminar Program (UK) 3
Epithelial and Vascular Control Mechanisms. Saxon River, VT, June 1998.
Visiting Lecturer, Department of Pharmacology, University of Tennessee Health Science
Center, Memphis, TN, December 1998. Aberrations in Renal Sympathetic Outflow Cause
Chronic Hypertension
Visiting Lecturer, Department of Pharmacology, University of Tennessee Health Science
Center, Memphis, TN, December 1998. Hands-On Science with Hands-On Scientists: Preparing
Americas Youth for the 21st Century .
Symposium Address: Creation of an Urban Based Academy of Science Wisconsin Annual
Conference on Charter Schools; February 22, 1999, Marquette University; Milwaukee, WI
Symposium, Transforming Urban Science Education. Experimental Biology 99, Washington,
D.C., April 1999.
Symposium, Long-Term Aberrations in Arterial Pressure Mediated by Renal Sympathetic
Nerve Activity. 6th Annual Conference on Sleep Disorders, Lake Louise, Alberta, Canada;
March 27-31, 1999.
Keynote Address, Inquiry based education in science and mathematics . PIMMS Leadership
Conference, Wesleyan University, October 2000.
Symposium, Inquiry-Based Teaching of Pathophysiology and Pharmacology to 11th and 12th
Grade Students. Experimental Biology 03, San Diego, CA; April 2003.
Featured Tutorial Lecture, Understanding and Using Molecular Biology to Study
Cardiovascular Function: From DNA to Organ Systems ; American College of Sports Medicine,
51st Annual Meeting, Indianapolis, IN; June 2-5, 2004.
Keynote Address: Wanted: Educational Leaders to Change the Face of Doing Business in
Schools . Kentucky Association for Equal Opportunities in Postsecondary Education,
Lexington, KY, October 19, 2005.
Symposium, Setting the Bar Higher, Michigan Association of Public Schools Academies,
Detroit, MI, October 27, 2006.
Other Professional Activities
American Journal of Physiology (Reviewer)
Renal, Fluid and Electrolyte Physiology
Regulatory, Integrative and Comparative Physiology
Heart and Circulatory Physiology
Hypertension (Reviewer)
Acta Physiologica Scandavica (Reviewer)
American Journal of Physiology: Advances in Physiology Education (Reviewer)
Clinical and Experimental Physiology and Pharmacology (Reviewer)
University, State and National Committees
University
1982-91 Graduate Qualifying Examination Committee, Dept. of Physiology, Medical College
of Wisconsin
1983-89 Research Affairs Committee, Medical College of Wisconsin
Chairman, 1984-88
Secretary 1988-89
1983-84 Graduate Admissions and Welfare Committee, Medical College of Wisconsin
1984-89 Human Research Review Committee, Medical College of Wisconsin
1985 Advisory Council on Development of "Health is Wealth", Discovery World, Milwaukee,
Wisconsin
1988-1992 Director, Science and Education Program, Medical College of Wisconsin
1989-1992 Admissions Committee, Medical College of Wisconsin
1994 -1996 Committee on Academic Standing, Medical College of Wisconsin
1994 -1997 Committee on School-to-work, Milwaukee Public Schools.
1999 Search Committee, Luce Professorship on Health and Human Rights, Trinity College
2000-2003 Center for Health Sciences Advisory Board, Trinity College
2001-2003 Institutional Animal Care and Use Committee, Trinity College
2003-2008 Executive Committee, Appalachian Math Science Partnership
2005-2006 External Review Committee, UK Undergraduate Studies Program
2006-2007 Biology Chair Search Committee, UK Department of Biological Science (member)
2005-2008 Institutional Animal Care and Use Committee, UK
2008-2009 Science Education Search Committee (Chair), Department of Curriculum &
Instruction, College of Education
2010-Present Beckman UG Research Scholars Committee, Chair
2009-Present Louis Stokes Alliance for Minority Participation, UK Campus Coordinator
2010-Present Lecturer Search Committee, Department of Biology, Chair
2011-Present Instructor Search Committee, Department of Biology, Chair
State
1988-1991 Chairman, Milwaukee WABRE Steering Committee, Committee on Education
1990-1992 President, Milwaukee Division, AHA/WI Affiliate
1989-1995 Research Peer Review Committee, American Heart Association/WI Affiliate
1992-1995 Chairman, Research Peer Review Committee, American Heart Association/WI
Affiliate
1990-1998 Board of Governors, AHA/WI Affiliate
1987-1999 Wisconsin Association for Biomedical Research and Education (WABRE), Member
1989-1999 Board of Directors, Wisconsin Association for Biomedical Research and Education
(WABRE)
President, 1993-1996
1995-1999 Sally Ride Academy, Board of Directors-Milwaukee, WI
2000- 2003 Connecticut Biobus (CURE), Advisory Board
2000- 2003 Connecticut State Department of Education Advisory Board on Gifted and
Talented Programs
2000-2003 Board of Directors, Biomedical Engineering Alliance and Consortium (BEACON) of
New England
2005-2010 Science Education Advisory Board, Louisville Science Center, Louisville, KY
2005-Present Board of Advisors, Partnership Institute for Math Science Education Reform
(PIMSER)
National
1989-1992 Water and Electrolyte Section of the American Physiological Society, Program
Committee
1993-1996 Animal Care and Experimentation Committee, American Physiological Society
1995-1996 Chairman, APS Animal Care and Experimentation Committee
995-1996 American Association for Accreditation of Laboratory Animal Care (AAALAC) -
Board of Directors
1997 American Heart Association Representative (WI), National Consensus Conference on
Research Programs for 21st Century
1998-1999 American Heart Association Northland Affiliate Research Committee
Vice-Chairman: 1998-1999
1997-1999 American Heart Association Midwest Consortium Peer Review Committee:
Cardiorenal Section
Co-Chairman: 1998
Chairman: 1999
1996-1999 American Heart Association Great America Peer Review Consortium Steering
Committee
Vice-Chairman: 1998-1999
Chairman: 1999
2000-2003 American Physiological Society Education Committee
1997-2006 American Association for Accreditation of Laboratory Animal Care (AAALAC): Ad
hoc Site Visitor - Special Emphasis
2006-2009 American Association for Accreditation of Laboratory Animal Care (AAALAC):
Regular Site Visitor
2006-Present Advisory Board, National Ambystoma Genetic Stock Center
2008-Present AHA Cardiorenal and Lung Peer Review Committee, Great Rivers Affiliate
Financial Resources (Grants and Contracts)
Currently Active
NSF#0733920 University of Kentucky NOYCE Fellows Program: New Opportunities Yielding
Classroom Excellence.
Margaret Mohr, Ph.D. University of Kentucky PI
Jeffrey L. Osborn, Ph.D. University of Kentucky Co-PI
Bruce Walcott, Ph.D. University of Kentucky Co-PI
Jana Bouwma-Gearhart University of Kentucky Co-PI
9/15/07-9/14/11 $748,625
Pending
NSF#1045486 New GK-12 UK E3: Connecting Kentucky Rural Appalachian and Suburban
Teachers in a Partnership for Environmental Science, Ecology and Evolution Education.
Jeffrey L. Osborn, Ph.D. University of Kentucky PI
Jana Bouwma-Gearhart, Ph.D University of Kentucky Co-PI
Vincent Cassone, Ph.D. University of Kentucky Co-PI
Peter Mirabito, Ph.D. University of Kentucky Co-PI
Philip Crowley, Ph.D. University of Kentucky Co-PI
1/11/11 12/31/15 $3,097,332
NSF#1044209 Building a New Understanding of Evolution by Transforming Undergraduate
Understanding of Bioscience Using Modeling-Based Inquiry Instruction.
Jeffrey L. Osborn, Ph.D. University of Kentucky PI
Jana Bouwma-Gearhart University of Kentucky Co-PI
Vincent Cassone, Ph.D. University of Kentucky Co-PI
Ruth Beattie, Ph.D. University of Kentucky Co-PI
Albert Corso, Ph.D. University of Kentucky Co-PI
1/1/11 12/31/13 $199,995
NSF#1068270 INQUiry-based Instruction for Retention, Investigation and Education in STEM
INQUIRIES.
Jeffrey L. Osborn, Ph.D. University of Kentucky PI
Ruth Beattie, Ph.D. University of Kentucky Co-PI
Jana Bouwma-Gearhart, DPhil. University of Kentucky Co-PI
Alison Soult, DPhil. University of Kentucky Co-PI
Stephen Testa, PhD University of Kentucky Co-PI
6/1/20115/31/2016 $1,967,114
Previous Grants or Contracts
The Medical College of Wisconsin, "Brain Angiotensin II and the Control of Renal
Function". Biomedical Research Support Grant. 7/1/81 - 6/30/82, $5,000
Wisconsin Heart Association Neural Control of Renal Prostaglandin and Renin Release.
7/1/81 - 6/30/83; $12,740 & 7/1/83 - 6/30/85; $13,997
"Brain Angiotensin II: Effects on Renal Function", Medical College of Wisconsin -
Institutional Research Support Grant. 6/1/82 -12/31/82; $3,800
Neuroadregernic Blood Pressure Control in Genetic Hypertension AHA Grant-in-Aid J.L.
Osborn, Ph.D. (PI) 7/1/97- 6/30/00; $60,000
Mechanisms of Renal Neuroadrenergic Hypertension AHA Grant-in-Aid J.L. Osborn, Ph.D.
(PI). 7/1/00- 6/30/02; $90,000
Brain Angiotensin II: Effects on Renal Function, Principal Investigator NIH HL 28303
7/1/82 - 12/30/85 $107,405
Neural Control of Renal Function in Unanesthetized Animals, J.L. Osborn, Ph.D. NIH PO1 HL-
29587 (PPG) 3/1/83 - 2/28/88; $181,926
Neural Regulation of Renal Function and Arterial Pressure J.L. Osborn, Ph.D. NIH PO1 HL-
29587 (PPG) 3/1/88 - 2/28/93; $348,486
Renal Metabolism of Fenoldopam. Smith Kline Beckman 10/1/86 - 6/30/88; $12,000
Established Investigator Award American Heart Association. 7/1/87 - 6/30/92; $175,000
High School Teacher Summer Fellowship Program. Faye McBeath Foundation. Jeffrey L.
Osborn, Ph.D. (PI). 6/30/88 - 12/30/92; $111,000
Neural Control of Renal Function in Hypertension. AHA Grant-in-Aid 7/1/88 - 6/30/90;
$46,582
Mechanisms of Intrarenal Noradrenergic Hypertension. AHA/WI Predoc. Fellowship to Suzanne
Greenberg. 7/1/88 - 6/30/90; $15,500
Sodium Intake and Neural Control of Arterial Pressure NIH RO1 HL-40137. 12/01/88 -
11/30/92; $223,164
Sodium Intake and Neural Control of Arterial Pressure Biomedical. Research Support Grant
11/1/91 - 10/31/92; $9,500
(PPG) Project 3 3/1/93 - 2/28/98; $518,281
Renal Neurogenic Mediation of Genetic Hypertension J.L. Osborn, Ph.D., Co-Investigator.
NIH R01 HL-354535 4/1/90 - 10/30/98; $877,096
MCW Center for Science Excellence. GE Medical Foundation. J.L. Osborn, Ph.D. 1/1/93-
12/31/98; $75,000
Center for Science Education Enhanced Middle School Science Education J.L. Osborn, Ph.D.
(PI) 4/1/97- 3/31/00; $75,000
Science Education Summer School Program Milwaukee Public School System J.L. Osborn, Ph.D.
(PI) 6/1/98 - 8/15/98; $202,865
The Milwaukee Academy of Science Development of a Charter School Wisconsin Department of
Public Instruction J.L. Osborn, Ph.D. (PI). 1/1/99-12/31/99; $20,000
Dorr Foundation Building Inquiry Based Chemistry Through Laboratory Instruction" Jeffrey
L. Osborn, Ph.D.
(PI) 1999-2002; $120,000
H.A. Vance Foundation A 9-12 Robotics & Electronics Program Jeffrey L. Osborn, Ph.D.
(PI) 1999-2002; $100,000
Hartford Courant Foundation Giants of Science Program Jeffrey L. Osborn, Ph.D. (PI)
1999-2002; $10,000
Arthur-Vining Davis Foundation Youth and learning in the 21st Century: A professional
Development model for Secondary School Educators in Diverse Urban Settings Jeffrey L.
Osborn, Ph.D. (PI) 2000-2003; $150,396
Toyota USA Foundation The Toyota USA Elementary Physics in Motion Program Jeffrey L.
Osborn, Ph.D. (PI) 2000-2003; $210,000
Connecticut State Department of Education Explorations in Science Jeffrey L. Osborn,
Ph.D. (PI) 2001-2003; $200,000
NSF #0119968 Connecting with the River: Geoscience Research and Education for Hartford,
CT. Jeffrey L. Osborn, Ph.D. (Co-PI) 2001 2004; $333,173
NSF#626955 A Genome Sequence for the Model Hemibiotroph Colletotrichum graminicola
Jeffrey L. Osborn, Ph.D. (Co-PI) 2006 2008; $951,260
NSF#0538465 Track 1, GK12, Algebra Cubed Jeffrey L. Osborn, Ph.D. (Co-PI) 2006 2009;
$1,974,644
DOE Teaching the Logic of the Scientific Method in the 4th grade Jeffrey L. Osborn, Ph.D.
(Co-PI) 2006 2009; $1,140,203
KY Dept. of Education Kentucky Science Alliance Jeffrey L. Osborn, Ph.D. (Co-PI) 2006
2009; $570,000
NSF #0437768 Assessing How Distance Learning for Teachers Can Enable Inquiry Science in
Rural Classrooms Jeffrey L. Osborn, Ph.D. (PI) 2005 2010; $1,998,882
NSF#0431552 Recruiting, Retaining, and Graduating University of Kentucky Appalachian
Science, Technology, Engineering, and Mathematics Majors Jeffrey L. Osborn, Ph.D. (Co-PI)
2005-2010; $1,998,906
Physical Facilities
Office
115 Thomas Hunt Morgan, University of KentuckyLaboratories
Renal Hypertension Lab: Room 205 Medical Research Building 3 (600 ft2)
Bioscience Education: Room 201 (750 ft2)
115B/C (250 ft2) T.H. Morgan
Sabbaticals Hosted
Mahendr Kochar, M.D. (1990)
Dissertation and Thesis Committees/Postdoctoral Fellows
Masters Thesis Directed
Joel N. Swerdel (Physiology) 1985
Samuel P. Carmichael, II (Biology) 2008
Dissertations Directed
Suzanne Greenberg (Physiology) 1990
Lawrence D. Nelson (Physiology) 1992
Amadou K.S. Camara (Physiology) 1995
Craig F. Plato (Physiology) 1997
Timothy Bradshaw (Biology) 2011
Dissertation Committees
Lawrence G. Pan (Physiology-MCW) 1983
Leonard B. Bell (Physiology-MCW) 1984
Michael J. Burke (Physiology-MCW) 1984
David C. Merrill (Physiology-MCW) 1984
Zeljko Dujic (Physiology-MCW) 1986
Jose Eduardo Krieger (Physiology-MCW) 1988
Verne E. Cowles (Physiology-MCW) 1989
David Mattson (Physiology-MCW) 1989
Sharon Lu (Physiology-MCW) 1993
Heather Drummond (Physiology-MCW) 1995
David Weber (Physiology-MCW) 1998Runze Wu (Biomedical Engineering-UK) 2005
Slone, Katrina (Curriculum & Instruction-UK) 2007
Crowe, Cheryl (Curriculum & Instruction-UK) 2008
Cunningham, Jessica (Educational Policy & Evaluation-UK) 2009
Knutson, Nicole (Educational Policy & Evaluation UK) 2011 expected
Craig F. Plato
Ph.D. 1997
Xiao Feng Li, M.D., Ph.D. 1996-1997
David Basile, Ph.D. 1997-1999
Graduate Students (Current)
Jason Collett (Biology) 2006-Present (Ph.D. Expected Aug. 2012)
Brandon Franklin (Biology
)
2011-Present
Undergraduate Research Fellows
University of Kentucky
Aaron D. Fain2005-2007 (Am. Physiol. Soc. Research Fellow 05- 06)
(Am. Physiol. Soc. Research Fellow 05- 06)
Jason Collett2005-2006
Julie Kretzer2006-2009 (Am. Physiol. Soc. Research Fellow 08- 09)
Elaine Patterson2006-2009
Rebecca Crutcher
2007-2009
Michelle O Brien
(Am. Physiol. Soc. Research Fellow 09- 10)
Pre-College Research Fellows
Hersh Patel2006-2007 (Paul Laurence Dunbar HS
MSTC Program)
Leslie Davis
2007-2009 (Paul Laurence Dunbar HS
MSTC Program)
Jiyang Zhang2008-2010 (Paul Laurence Dunbar HS MSTC Program)
Bibliography
Books, Chapters and Invited Reviews
Thames, M.D., and J.L. Osborn. "Role of Renal Nerves in Regulation of Renin Secretion."
In: Yearbook of Science and Technology. New York: McGraw-Hill, Inc., 1981, pp. 336-339.
Osborn, J.L., M.D. Thames and G.F. DiBona. "Neural Control of Renin Secretion: Nature of
Prostaglandin Interactions." In: Prostaglandins and the Kidney: Biochemistry, Pharmacology
and Clinical Application. New York: Plenum Publishing Corp., 1982, pp. 185-188.
Bailie, M.D., J.L. Osborn and J.B. Hook. "The effect of prostaglandin synthesis and
angiotensin II on renal function in the newborn piglet." In: The Kidney During
Development, A. Spitzer, ed. New York: Masson Publishing Inc., 1984.
Mattson, D.L. and J.L. Osborn. Renal Physiology . In: Physiology Secrets, H. Raff, ed.,
Philadelphia, PA, Hanley and Belfus, Inc., 1999. pp. 101-135.
Osborn, J.L. and S.Greenberg. Renal Nerves and Extracellular Fluid Volume Regulation:
Hypertension Primer 2nd ed.; J.L. Izzo, Jr. and H.R. Black, editors; pages 89-91, 1999.
Osborn, J.L., Suzette Svoboda-Newman, Jill Crowder, Larietta Jenkins and Marsha Lakes
Matyas. The Kidney Under Pressure in Frontiers in Physiology, Marsha Lakes Matyas, ed.,
1999
Osborn, J.L. and C.F. Plato. Neural Control of Renal Function . In: Clinical and
Experimental Nephrology. S. Massry and R. Glassock ed., 2003.
Osborn, J.L and S.G. Greenberg. Renal Nerves and Extracellular Fluid Volume Regulation.
Hypertension Primer 3rd ed.; J. L. Izzo, Jr. And H.R. Black, editors; pages 108-111, 2003.
Bradshaw, T., Carmichael S., Collett, J., Ferrier, A. and J. L. Osborn. Using vernier
equipment to convert didactically taught human respiration lab to inquiry based human
respiration lab. in Tested Studies for Laboratory Teaching, Volume 29 (K.L. Clase,
Editor); pp 188-204,. Proceedings of the 29th Workshop/Conference of the Association for
Biology Laboratory Education (ABLE), 2008.
Publications
Hook, J.B., R. Cordona, J.L. Osborn, M.D. Bailie and P.J. Gehring. The renal handling of
2,4,5 trichlorophenoxyacetic acid (2,4,5-T) in the dog. Food Cosmet. Toxicol. 14: 19-23,
1976.
Osborn, J.L., J.B. Hook and M.D. Bailie. Control of renin release: effects of D-
propranolol and renal denervation on furosemide induced renin release in the dog. Circ.
Res. 41(4): 481-486, 1977.
Osborn, J.L., B. Noordewier, J.B. Hook and M.D. Bailie. Mechanism of prostaglandin E2
stimulation of renin release. Proc. Soc. Exp. Biol. Med. 159: 249-252, 1978.
Osborn, J.L., J.B. Hook and M.D. Bailie. Effect of saralasin and indomethacin on renal
function in developing pigs. Am. J. Physiol. 235(5): R438-R442, 1980.
Osborn, J.L., J.B. Hook and M.D. Bailie. Regulation of plasma renin in developing pigs.
Dev. Pharmacol. Ther. 1: 217-228, 1980.
Wallace, K.B., J.L. Osborn and M.D. Bailie. Species difference in kinetics of renin
substrate reaction in plasma. J. Pharmacol. Methods 4: 141-154, 1980.
Osborn, J.L., G.F. DiBona and M.D. Thames. Beta-1 adrenoceptor mediation of renin
secretion elicited by low frequency renal nerve stimulation. J. Pharmacol. Exp. Ther. 216:
265-269, 1981.
Osborn, J.L., U.C. Kopp and G.F. DiBona. Ischemic acute renal failure: newer implications
of stopped pipes. J. Clin. Med. 98: 16-20, 1981.
Osborn, J.L., L.L. Francisco and G.F. DiBona. Effect of renal nerve stimulation on renal
blood flow autoregulation and antinatriuresis during reductions in renal perfusion
pressure. Proc. Soc. Exp. Biol. Med. 168: 77-81, 1981.
DiBona, G.F., E.J. Johns and J.L. Osborn. The effect of vagotomy on sodium reabsorption
and renin release in anesthetized dogs subjected to 60 head-up tilt. J. Physiol. 320: 293-
302, 1981.
Osborn, J.L., M.D. Thames and G.F. DiBona. Role of macula densa in renal nerve modulation
of renin secretion. Am. J. Physiol. 242: R367-R371, 1982.
Francisco, L.L., J.L. Osborn and G.F. DiBona. The role of prostaglandins in macula densa
mediated rise in plasma renin activity. Am. J. Physiol. 243 (Renal, Fluid and Electrolyte
Physiol.): F537-F542, 1982.
Osborn, J.L., G.F. DiBona and M.D. Thames. Role of alpha adrenoceptors mediating renin
secretion. Am. J. Physiol. 242 (Renal, Fluid and Electrolyte Physiol.): F620-F626, 1982.
Osborn, J.L., M.D. Thames and G.F. DiBona. Renal nerves modulate renin secretion during
autoregulation. Proc. Soc. Exp. Biol. Med. 169: 432-437, 1982.
Osborn, J.L., H. Holdaas, M.D. Thames and G.F. DiBona. Renal adrenoceptor mediation of
antinatriuretic and renin secretion responses to low frequency renal nerve stimulation in
the dog. Circ. Res. 59(3): 298-305, 1983.
Osborn, J.L., L.G. Hoversten and G.F. DiBona. Impaired blood flow autoregulation in
nonfiltering kidneys: effect of theophylline. Proc. Soc. Exp. Biol. Med. 174: 328-355,
1983.
Osborn, J.L., U.C. Kopp, M.D. Thames and G.F. DiBona. Interactions among renal nerves,
prostaglandins and renal arterial pressure in the regulation of renin release. Am. J.
Physiol. 247 (Renal, Fluid and Electrolyte Physiol.): F706-F713, 1984.
Seagard, J.L., F.A. Hopp, Z.J. Bosnjak, J.L. Osborn and J.P. Kampine. Sympathetic
efferent nerve activity in conscious and isoflurane-anesthetized dogs. Anesthesiology 61:
266-270, 1984.
Osborn, J.L., R.J. Roman and R.W. Harland. Mechanisms of antinatriuresis during low
frequency renal nerve stimulation in anesthetized dogs. Am. J. Physiol. 249 (Regulatory,
Integrative and Comp. Physiol.): R360-367, 1985.
Osborn, J.L., and M.T. Lawton. Neurogenic antinatriuresis during acute cardiac tamponade.
Am. J. Physiol. 250: 195-202, 1986.
Cowley, A.W. Jr., B.J. Barber, J.H. Lombard, J.L. Osborn and J.F. Liard. Relationship
between body fluid volumes and arterial pressure. Fed. Proc. 45: 2864-2870, 1986.
Roman, R.J., and J.L. Osborn. Renal function and sodium balance in conscious Dahl S and R
rats. Am. J. Physiol. 252 (Regulatory, Integrative and Comp. Physiol. 21): R833-R841,
1987.
O'Hair, D.P., M.B. Adams, J.L. Osborn and E.V. Buchmann. Computerized calculation of
radioimmunoassay determined cyclosporin A levels. Informatics in Pathology 1: 57, 1987.
Osborn, J.L., and D.D. Kinstetter. Neural control of renin release: effects of altered
sodium chloride intake. Am. J. Physiol. 253: F976-F981, 1987.
Osborn, J.L., R.J. Roman and J.D. Ewens. Renal nerves, sodium balance and development of
hypertension in Dahl salt sensitive rats. Hypertension 11(6): 523-528, 1988.
Osborn, J.L., and R.W. Harland. Alpha-1 adrenoceptor mediation of urinary bicarbonate
excretion. Am. J. Physiol. 255 (Renal, Fluid and Electrolyte Physiol. (24): F1116-F1121,
1988.
Osborn, J.L., and E.J. Johns. Renal sympathetic regulation of renin and prostaglandin
release. Min. Electrolyte Metab. 15: 51-58, 1989.
Osborn, J.L., and T.G. Curro. Renal sympathetic nerve activity and arterial pressure
responses to changes in postural position of conscious dogs. Proc. Soc. Exp. Biol. Med.
192: 258-254, 1989.
O'Hair, D.P., T.C. Tunberg, M.B. Adams and J.L. Osborn. Relationships among endotoxemia,
arterial pressure and renal function in dogs. Circ. Shock 27: 199-210, 1989.
Lombard, J.H., H. Eskinder, K. Kauser, J.L. Osborn and D.R. Harder. Enhanced
norepinephrine sensitivity in renal arteries at elevated transmural pressure. Am. J.
Physiol. 259 (Heart Circ. Physiol.): H29-H33, 1990.
Marsh, D.J., J.L. Osborn and A.W. Cowley, Jr. Fluctuations in arterial pressure and the
regulation of renal blood flow in dogs. Am. J. Physiol. 258 (Renal, Fluid and Electrolyte
Physiol.): F1394-F1400, 1990.
Osborn, J.L. Relationships between sodium intake, renal function and arterial pressure.
Hypertension 17: I91-I96, 1991.
Greenberg, S.G., S. Tershner and J.L. Osborn. Neurogenic regulation of the rate of
achieving sodium balance after increasing sodium intake. Am. J. Physiol. 261: F300-F307,
1991.
Dawson, C.A., A.W. Cowley, Jr., G.B. Spurr, J.L. Osborn, H. Raff, H.V. Forster, D.R.
Harder, J.F. Liard, J.H. Lombard and W.J. Stekiel Performance on multiple choice/short
answer tests is not a sufficient criterion for evaluating the educational value of live
animal laboratories in the teaching of physiology. Am. J. Physiol. 261: S34a 35, 1991.
Nelson, L.D., and J.L. Osborn. Neurogenic control of renal function in response to graded
nonhypotensive hemorrhage in conscious dogs. Am. J. Physiol. Reg., Integ. and Comp.
Physiol. 264: R661-R667, 1993.
Nelson, L.D., and J.L. Osborn. Role of intrarenal ANG II in the reflex neural stimulation
of plasma renin activity and renal sodium reabsorption. Am. J. Physiol. Reg., Integ. and
Comp. Physiol. 265: R392-R398, 1993.
Greenberg, S.G., C. Enders and J.L. Osborn. Renal neurogenic influence on the rate of
achieving sodium balance in the adult SHR. Hypertension 22: 1-8, 1993.
Greenberg, S., and J.L. Osborn. Relationship between sodium balance and renal innervation
during hypertension development in SHR. J. Hypertens. 12: 1359-1364, 1994.
Swart, G.L., J.R. Mateer, D.J. De Behnke, S.J. Jameson and J.L. Osborn. The effect of
compression duration on hemodynamics during mechanical high-impulse cardiopulmonary
resuscitation. Acad. Emerg. Med. 1: 430-437, 1994.
Johnson, C.P., S.K. Sarna,, V.E. Cowles, J.L. Osborn, Y.R. Zhu, L. Bonham, E. Buchmann,
R. Baytiyeh, G.L. Telford, and A.M. Roza. Motor activity and transit in the autonomically
denervated jejunum. Am. J. Surg. 167(1): 80-88, 1994.
Plato, C.F. and J.L. Osborn. Chronic renal neuroadrenergic hypertension is associated
with increased renal norepinephrine sensitivity and volume contraction. Hypertension
28:1034-1040, 1996.
Osborn, J.L., C.F. Plato, X.R. He and E. Gordin. Impact of long-term increases in
sympathetic activity on arterial pressure regulation. Clinical and Exp. Pharm. Physiol.
24: 72-76, 1997.
Camara, A.K.S., and J.L. Osborn. Renal neurogenic mediation of intracerebroventricular
AII hypertension in rats raised on high sodium chloride diet. Hypertension 30: 331-336,
1997.
Camara, A.K.S. and J.L. Osborn. AT1 receptors mediate chronic central nervous system AII
hypertension in rats fed high sodium chloride diet from weaning. JANS. 72:16-23, 1998.
Camara, A.K.S. and J.L. Osborn. i*!-Adrenergic systems mediate chronic central AII
hypertension in rats fed high sodium chloride diet from weaning. JANS 73:12-18, 1998
Basile, D.P., D. Donohoe, K. Roethe and J.L. Osborn. Renal ischemic injury results in
permanent damage to peritubular capillaries and influences long-term function. Am. J.
Physiol. (Renal, Fluid and Electrolyte Physiol.) 281: F887-F899, 2001.
Koehler, C., D. Moss and J.L. Osborn. The Learning Corridor: Exploring an Urban Magnet
School Initiative. 2002 Proceedings of the Association for the Education of Teachers in
Science: 1053-1067, 2002.
Stocker, S.D., J.L. Osborn, and S.P. Carmichael. Forebrain Osmotic Regulation of the
Sympathetic Nervous System. Clinical and Experimental Pharmacology and Physiology 35,695-
700, 2008.
Cunningham, J. D., K.D. Bradley, and J. Osborn. Assessing the impact of Newton s
Universe: Preliminary findings associated with rural school students and teachers
outcomes linked to inquiry-based physical science. ERS Spectrum, 62: 39-44, 2008.
McNall Krall, R., J.P. Straley, Jr., S.A. Shafer, and J.L. Osborn. Hands-on at a
Distance: Evaluation of a Distance Learning Temperature and Heat Course. J. Sci. Educ.
Technol. 18 (2); 173-186, 2009.
Bradshaw, T.J., S.P. Carmichael II, A.F. Ferrier, and J.L. Osborn. Supporting Inquiry
Instruction in Weekly Training Increases Teaching Assistants Confidence in Student
Content Knowledge. Adv. Physiol. Educ. (submitted for publication).
Bradshaw, T.J., R. Krall, W.S. Rayens, J.D. Cunningham, J.P. Straley, S.A. Shafer, K.D.
Bradley, and J.L. Osborn. Improving Student Understanding of Temperature and Heat Through
Distance Learning Professional Development for Teachers. Research in Science Education.
(submitted for publication)
Bradshaw, T.J., S.A. Shafer, K.D. Bradley, J.P. Straley and J.L. Osborn. Impact of
Newton s Universe Materials on Middle School Teacher and Student Understanding of Physical
Science. Research in Science Education. (submitted for publication)
Collett, J.A., A. Hart, E. Patterson, J.K. Kretzer and J.L. Osborn. Angiotensin II, Type
1 Receptor Expression and Elevated Arterial Pressure in Spontaneously Hypertensive
Rat/Brown Norway Backcross Rats. Am. J. Physiol. Reg., Integ. and Comp. Physiol.
(Submitted for Publication).
Abstracts
(* presented)
*Bailie, M.D., J.L. Osborn, W.A. Corsini and J.B. Hook. Furosemide induced renin
secretion: effect of propranolol and renal denervation. Kidney Int. 8: 437, 1975.
*Osborn, J.L., B. Noordewier, J.B. Hook and M.D. Bailie. Effect of prostaglandin E2
(PGE2) and other vasodilators on renin secretion (RS). Pharmacologist 19(2): 159, 1977.
*Osborn, J.L., W.A. Corsini, J.B. Hook and M.D. Bailie. Effect of propranolol (P) and
renal denervation on furosemide (F) induced renin secretion (RS). Clin. Res. 23: 507A,
1975.
*Osborn, J.L., J.B. Hook and M.D. Bailie. Effect of saralasin and indomethacin on renal
blood flow in newborn pigs. Fed. Proc. 37: 306, 1978.
*Osborn, J.L., J.B. Hook and M.D. Bailie. The effect of indomethacin on renal blood flow
in developing pig kidneys. Physiologist 21(4): 87, 1978.
*Osborn, J.L., J.B. Hook and M.D. Bailie. Excretion of saline load in newborn piglets:
Effect of BSA. Kidney Int. 14: 772, 1978.
Osborn, J.L., J.B. Hook and M.D. Bailie. Regulation of plasma renin in developing pigs.
Ped. Res. 13: 517, 1979.
*Osborn, J.L., K.P. Swabash, J.B. Hook and M.D. Bailie. Renal vascular patterns in
developing piglets. Fed. Proc. 38(3): 1036, 1979.
*Wallace, K.B., J.L. Osborn, J.B. Hook and M.D. Bailie. Re-evaluation of methods for
measuring plasma renin concentration. Fed. Proc. 38: 892, 1979.
Osborn, J.L., and G.F. DiBona. Effect of low level renal nerve stimulation during aortic
constriction on renin secretion in filtering and nonfiltering kidneys. Physiologist 22(4):
97, 1979.
*Osborn, J.L., M.D. Thames and G.F. DiBona. Modulation of renin secretion by renal nerves
after suprarenal aortic constriction in dogs. Clin. Res. 27(4): 668A, 1979.
*Osborn, J.L., and G.F. DiBona. Renal nerve modulation of renin secretion after aortic
constriction in the range of autoregulation. Kidney Int. 16(6): 795, 1979.
*Osborn, J.L., G.F. DiBona and M.D. Thames. Role of beta receptors in renin secretion:
effect of beta 1 receptor blockade with atenolol. Fed. Proc. 39(3): 826, 1980.
Francisco, L.L., J.L. Osborn and G.F. DiBona. The role of prostaglandins in macula densa
mediated renin release in the rat. Fed. Proc. 39(3): 826, 1980.
*Osborn, J.L., G.F. DiBona and M.D. Thames. Effect of alpha adrenergic blockade on renin
secretion mediated by low level renal nerve stimulation. Clin. Res. 28(2): 335A, 1980.
*Osborn, J.L., L.L. Francisco and G.F. DiBona. Effect of renal nerve stimulation on blood
flow autoregulation. Physiologist 23: 162, 1980.
Thames, M.D., J.L. Osborn and G.F. DiBona. Renin release mediated solely by renal nerves:
inhibition by blockade of prostaglandin synthesis. Circ. 62 (Suppl. III): III-222, 1980.
*Osborn, J.L., M.D. Thames and G.F. DiBona. Role of intrarenal alpha adrenoceptors
mediating renin secretion. Fed. Proc. 40: 553, 1981.
DiBona, G.F., and J.L. Osborn. Nature of renal tubular adrenoceptor mediating neural
regulation of sodium reabsorption. Fed. Proc. 40: 553, 1981.
Osborn, J.L., and G.F. DiBona. Theophylline restores blood flow autoregulation in
nonfiltering kidneys. Clin. Res. 29: 473A, 1981.
*Osborn, J.L., and G.F. DiBona. Neural control of renin secretion: Nature of intrarenal
adrenoceptor. Proceedings of the VIII International Congress of Nephrology, Athens,
Greece. p. 163.
*Osborn, J.L., M.D. Thames and G.F. DiBona. Neural control of renin secretion:
contributions of renal prostaglandins, alpha and beta, adrenoceptors. Circ. 64: IV-222,
1981.
Osborn, J.L., M.I. Phillips and M.J. Fregly. Increase in plasma renin activity (PRA) by
centrally administered angiotensin II and serotonin in rats. Endocrinology 108 (Suppl. I):
308, 1981.
*Osborn, J.L., U.C. Kopp, M.D. Thames and G.F. DiBona. Prostaglandin and B1 adrenoceptor
mediation of neural influences on renin secretion. Kidney Int. 21: 263, 1982.
*Osborn, J.L., U.C. Kopp, M.D. Thames and G.F. DiBona. Neural control of renin secretion:
evidence for prostaglandin dependent and independent pathways. Physiologist 25: 318, 1982.
*Osborn, J.L., and R.J. Roman. Influence of low frequency renal nerve stimulation on
renal sodium bicarbonate excretion. Fed. Proc. 42: 737, 1983.
Swerdel, J.N., and J.L. Osborn. Clonidine induced natriuresis: Role of renal innervation.
Fed. Proc. 42: 998, 1983.
*Osborn, J.L. Baroreflex control of renal nerve activity in conscious and anesthetized
dogs. Circ. 68: III-78, 1983.
Hopp, F.A., J.L. Seagard, J.L. Osborn and J.P. Kampine. A comparison of four methods of
analysis of efferent nerve activity. Physiologist 26: A-103, 1983.
Seagard, J.L., F.A. Hopp, J.L. Osborn and J.P. Kampine. Effects of isoflurane on
chronically recorded sympathetic efferent nerve activity. Physiologist 26: A-103, 1983.
*Osborn, J.L., and M.T. Lawton. Neurogenic antinatriuresis during acute cardiac
tamponade. Kidney Int. 25: 312, 1984.
Swerdel, J.N., T.G. Curro and J.L. Osborn. Influence of renal nerve stimulation on
cardiovascular function. Fed. Proc. 43: 1069, 1984.
*Osborn, J.L., and C. Leahy Nicholas. Effects of brain angiotensin II on renal function
of conscious rats. Fed. Proc. 43: 994, 1984.
*Osborn, J.L., and G.E. Huhnke. Effects of angiotensin II on regulation of renal nerve
activity in conscious dogs. Kidney Int. 27: 197, 1985.
Swerdel, J.N., and J.L. Osborn. Transient renal excretory responses to elevated sodium
chloride intake of conscious rats. Fed. Proc. 44: 1011, 1985.
*Osborn, J.L., and D. Kinstetter. Neural control of renin secretion in sodium deplete and
sodium loaded dogs. Fed. Proc. 44: 1363, 1985.
*Osborn, J.L., J.D. Ewens and R.J. Roman. Renal Nerves, sodium balance and development of
hypertension in Dahl S rats. Fed. Proc. 45: 522, 1986.
*Osborn, J.L. Time course of achieving sodium balance after decreasing sodium intake:
role of renal innervation. Kidney Int. 31: 306, 1987.
Nicolosi, A.C., D.P. O'Hair, M.B. Adams and J.L. Osborn. Resuscitation from endotoxic
shock in canines. Fed. Proc. 46: 805, 1987.
O'Hair, D.P., M.B. Adams, T.C. Tunberg and J.L. Osborn. Relationships between
endotoxemia, arterial pressure, and renal function in dogs. Fed. Proc. 46: 805, 1987.
*Osborn, J.L. Functional role of renal nerves in control of sodium balance in conscious
rats. Proceedings of the Xth International Congress of Nephrology (London)., p. 29, 1987.
*Osborn, J.L., and P.J. Drysdale. Pattern of urinary sodium (Na) excretion in conscious
dogs on fixed normal and low sodium intakes. FASEB J. 2(5): 1318, 1988.
Greenberg, S., S.A. Tershner and J.L. Osborn. Rate of increasing urinary sodium excretion
is reduced by renal nerves following a step increase in sodium intake. FASEB J. 2(5):
A1319, 1988.
*Osborn, J.L. Neurogenic mediation of antinatriuresis following reduction of sodium
intake in conscious dogs. Kidney Int. 35: 471, 1989.
Jarenwattananon, M., A. Camara, J. Ciezki and J.L. Osborn. Cardiovascular effects of
milrinone in neonatal swine. Ped. Res. 25: 67A, 1989.
Greenberg, S., and J.L. Osborn. Rate of achieving sodium balance after decreasing sodium
intake in spontaneously hypertensive rats. FASEB J. 3(4): A1304, 1989.
*Osborn, J.L., S. Tershner and C. Hinojosa-Laborde. Sodium and water retention during
development of renal wrap hypertension. Hypertension 14: 338, 1989.
Greenberg, S.G., and J.L Osborn. Restriction of fluid intake reduces the rate of
achieving sodium balance. FASEB J. 4: A412, 1990.
Nelson, L.D., and J.L. Osborn. Neurogenic control of renal function in response to graded
nonhypotensive hemorrhage. FASEB J. 4: A564, 1990.
Greenberg, S.G., and J.L. Osborn. Relationship between sodium balance and renal
innervation during hypertension development in the SHR. FASEB J. 5: A663, 1991.
Nelson, L.D., and J.L. Osborn. High and low sodium intake inhibits neurogenic regulation
of renal function. FASEB J. 5: A736, 1991.
*Osborn, J.L., E. Gordin and P. Drysdale. Low level intrarenal norepinephrine causes
hypertension in dogs. Am. J. Hypertens. 4: 74A, 1991.
Browne, B.J., C.J. Johnson, A.M. Roza, J.L. Osborn and M.B. Adams. A rat model of in vivo
neural isolation: tra
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