Engineering Medical
Resume:
Curriculum Vitae Thomas P. Hedman
Ph.D.
Page * of 32
CURRICULUM VITAE
A. Personal Information
Name in full Thomas Paul Hedman, Ph.D.
Mailing Address 337 Zachry Engineering Center, 3120 TAMU College Station, TX 77843
Cell Phone 512-***-****
Work Phone 866-***-****
Fax 859-***-****
Place of Birth Minneapolis, Minnesota
Citizenship U.S.A.
E-mail Addresses aboxfe@r.postjobfree.com, aboxfe@r.postjobfree.com, aboxfe@r.postjobfree.com
Web Pages www.orthopeutics.com, http://biomed.tamu.edu/faculty_detail.asp?lname='Hedman',
www.intralink-spine.com, www.orthopeutics.com
B. Education
High School Fridley High School, Fridley, MN, 1979
College or University University of Minnesota, Institute of Technology, Minneapolis,
B.S.M.E., With
Distinction, 1983
Graduate School Massachusetts Institute of Technology, Cambridge, S.M.M.E., 1985
University of Strathclyde, Glasgow, Scotland, Ph.D., 1995
Honors and Awards B.S. in Mechanical Engineering awarded with distinction,
J. Palmer Hermundslie Memorial Scholarship (Medtronics, Inc.) recipient.
Dean's list: University of Minnesota, Institute of Technology
C. Professional Background
Academic Appointments
2009 to presentJoint Associate Professor, Department of Surgery, Texas A&M Health
Science Center
College of Medicine
2007 to presentResearch Associate Professor, Biomedical Engineering Department, Texas
A&M University
2007 to presentResearch Associate Professor, Texas Engineering Experiment Station, Texas
A&M System
2007Senior Research Scientist, Mechanical Engineering Department, Cockrell School of
Engineering, University of Texas
2006 to 2007Adjunct Associate Professor, Division of Biokinesiology and Physical
Therapy, University
of Southern California
2003 to 2005Associate Professor of Research, Department of Orthopaedic Surgery, Keck
School of
Medicine of the University of Southern California
2003 to 2007Research Associate Professor, Department of Biomedical Engineering, School
of
Engineering, University of Southern California
2003Research Assistant Professor, Department of Biomedical Engineering,
School of
Curriculum VitaeThomas P. Hedman
Ph.D.
Page 2 of 32
Engineering,
University of Southern California19942003Assistant Professor of Research, Department of Orthopaedic Surgery, Keck
School of
Medicine of the University of Southern California
Teaching Responsibilities
Seminars: Entrepreneurial Issues in Biomedical Engineering, Texas A&M, 2008
Lectures to USC Orthopaedic Residents (1-3 per year), 1995 2004, Covering Various
Topics in Orthopaedic
Biomechanics, Soft-Tissue and Spinal Biomechanics, Orthopaedic Biomaterials, Statistics
Co-Instructor: Introduction to Biomaterials (USC Biomed. Eng. Dept.) BME410, Spring 2000-
2002, Fall
2002-2005, Ave. Student Evaluation 3.95/5.0 (Above Average)
Lecturer to First Year Medical Students-Musculoskeletal Section, USC, 202
Other Responsibilities
2007 present Founder, Chief Scientific Officer, Chairman, Intralink Spine, Inc.
20052006Director of Biomechanics and Spinal Research, Institute for Spinal Disorders,
Cedars-Sinai
Medical Center
2004 present
Founder, Chief Scientific Officer, and General Partner, Orthopeutics, L.P
.
2001presentFounder and President, Ampac Biotechnology, Inc
.
19942004Founder and Owner of New Life Publications
20012004 Member, USC Anatomical Gift Program Oversight Committee
1995 2005 Department Representative (or alternate): USC Medical Faculty Assembly
2004 2005 Alternate Department Representative: Faculty Appointments, Promotions and
Tenure
Committee
1995 2004 Member, Orthopaedic Resident Research Committee
19942004Director, USC Orthopaedic Research Laboratory, University of Southern
California
19911994Interim Director, Arthritis Centre, Biomechanics Laboratory, The Toronto
Hospital
Other Employment or Activity
1995 2007 Judge-Applied Mechanics, California State Science Fair
1995 2003 Volunteer, HOPE Worldwide, Immunization awareness and other community
projects
19851994Research Associate, The Toronto Hospital
19831985Research Assistant, Massachusetts Institute of Technology
19811983Engineering Assistant Trainee, University of Minnesota,
Physical Plant
1980
Engineering Intern, Metropolitan Council,
Division of Solid Waste Management, St.
Paul
Conference Moderation and Organization2001- 2002Co-Chair, Basic Science Committee, SICOT/SIROT
2003 Moderator, Basic Science Forum, Northern Region Congress APOA
Journal Peer Review
1994-presentAd Hoc Reviewer to Editors of Neurosurgery Journal
1999-presentAd Hoc Reviewer to Editors of Journal of Biomechanics
2000-present Ad Hoc Reviewer to Journal of Bone and Joint Surgery
2003-present Ad Hoc Reviewer to Journal of Clinical Biomechanics
Curriculum Vitae
Thomas P. Hedman
Ph.D.
Page 3 of 32
2007-present Reviewer, Spine Arthroplasty Society On-Line Journal
2007-presentEditorial Staff, Spine Arthroplasty Society On-Line Journal
2008-present Reviewer, Spine topic, Orthopaedic Research Society Annual Meeting
2010-present Ad Hoc Reviewer to Biomechanics and Modeling in Mechanobiology
2010-present Ad Hoc Reviewer to Journal of Orthopaedic Research
Federal Grant Review
2009 NIAMS Challenge Grant Ad Hoc Reviewer
2010-present NIAMS Orthopedic and Skeletal Biology Special Emphasis Panel Reviewer
Graduate Theses Supervised
Fleming Chu, M.S., The Biomechanical Effects of Spinal Fusions on the Adjacent Unfused
Segment,
Biomedical Engineering Department, University of Southern California, May 2001.
Dean Gray, M.S., A Preliminary Investigation to Determine the Effects of a Crosslinking
Reagent on the
Fatigue Resistance of the Posterior Annulus of the Intervertebral Disc, Biomedical
Engineering
Department, May 2002.
Brendan S-Y Chuang, M.D., M.S., Viscoelastic Homogeneity, Recovery, and Hydration in Rat
Tail
Intercaudal Discs, Biomedical Engineering Department, May 2004.
Baber Syed, M.S., Destructive and Non-Destructive Approaches for Quantifying the Effects
of a Collagen
Crosslinking Reagent on the Fatigue resistance of Human Intervertebral Disc, Biomedical
Engineering
Department, September 2004.
Brendan S-Y Chuang, M.D., Ph.D., The Effects of Crosslink Augmentation on the Stability
of Spinal Motion
Segments and the Poroelastic Properties of Intervertebral Discs, Biomedical Engineering
Department,
May 2005.
r
Jiang Guangquiang, Ph.D., Development of Ceramic to Metal Package For BION
Microstimulator,
Biomedical Engineering Department, May 2005.
Stephanie Hsu, M.D., M.S., Mechanical Engineering Department, May 2005.
Varun Bhardwaj, MS, Quantification Of Intervertebral Disc Collagen Cross-Links Using An
Enzymatic
Degradation Technique, Biomedical Engineering Department, University of Southern
California,
September 2007.
Judson Welcher, Ph.D. Candidate, Development of a new method to measure the temporal and
spatial loads in
the lumbar facet joint, Biomedical Engineering Department, University of Southern
California, In
Progress.
John Popovich, DPT, Ph.D., Division of Biokinesiology and Physical Therapy, University of
Southern
California, October 2010.
Curriculum Vitae
Thomas P. Hedman
Ph.D.
Page 4 of 32
Jonathan Golightly, MS, Confined compression testing of crosslinked annulus fibrosus,
Biomedical
Engineering Department, Texas A&M University, May 2009.
Bryan Kirking, Ph.D. Candidate, Biomedical Engineering Department, Texas A&M University,
In Progress.
Awards and Honors
Charles S. Neer Award for Basic Science Research, American Shoulder and Elbow Surgeons
Society, 1997.
D. Society Memberships
National
1992 present American Society of Mechanical Engineers
1987 present American Society of Testing and Materials (ASTM)
1987 present American Society of Testing and Materials (ASTM-F04) Medical and Surgical
Materials and Devices
1990 present American Society of Testing and Materials (ASTM-F04.25) Spinal Devices
1990 present American Society of Testing and Materials (ASTM-F04.25.01) Spinal
terminology
subcommittee member
1990 present American Society of Testing and Materials (ASTM-F04.25.04) Construct
testing
subcommittee member
2007 present North American Spine Society
International
1999 present Orthopaedic Research Society
2001 2007 International Society of Biomechanics
2007 present Spine Arthroplasty Society
E. Research Activities
Complete Bibliography Appended
Major Areas of Interest
Biomechanics / Orthopaedic biomechanics / Spinal biomechanics
Injectable Tissue Engineering
Degeneration in the lumbar spine
Development and testing of new technologies
Intervertebral disc matrix modification using injectable collagen crosslinking
Research in Progress
Curriculum VitaeThomas P. Hedman
Ph.D.
Page 5 of 32
Benefits of endogenous crosslinks and non-toxic crosslinking reagents on intervertebral
disc and
other collagenous tissues
Characterization of chemical crosslinking of collagen using biomechanical and biochemical
crosslink
quantification techniques
Research Funding
Federal:
Modification of Intervertebral Disc Fatigue Resistance $100,000
NIAMS NIH, STTR Grant to Ampac Biotechnology, Inc.
1 R41 AR47470-01A1, 2001 - 2002, Principal Investigator
Nonsurgical Exogenous Crosslink Therapy for Intervertebral Disc Disease $ 70,718
NIAMS NIH, SBIR Grant to Ampac Biotechnology/Orthopeutics
1 R43 AR055014-01, 8/20071/2008, Principal Investigator
Nonsurgical Exogenous Crosslink Therapy for Intervertebral Disc Disease $ 767,900
NIAMS NIH, SBIR Grant to Ampac Biotechnology/Orthopeutics
2R44AR055014-02A1, 2/1/2010 1/31/2012, Principal Investigator
State:
Nonsurgical Exogenous Crosslink Therapy for Intervertebral Disc Disease $ 408,000
Kentucky SBIR Matching Grant to Ampac Biotechnology/Orthopeutics
7/1/20106/30/2011, Principal Investigator
Foundation:
Mechanical response of lumbar spines $ 135,000
Arthritis Society of Canada
1991 - 1994, Co-investigator
Fibular Fracture Reconstruction $ 20,000
American Orthopaedic Association
1995 - 1996, Co-investigator
Industry:
Development of an Intervertebral Disc Prosthesis $1,200,000
MDS Health Group, Toronto
1985 - 1991, Co-investigator
Evaluation of absorbable screws in ankle syndesmosis $ 21,000
Johnson & Johnson
1994 - 1995, Co-investigator
Development and testing of various orthopaedic implants $ 145,000
Curriculum Vitae
Thomas P. Hedman
Ph.D.
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ACE Medical Company1995 - 1998, Principal Investigator
Bone anchor comparative testing, interbody fusion device, $ 12,000
disc replacement development and testing
Li Medical Technologies, Inc.
1995 - 2000, Principal Investigator
Cable and cable construct testing $ 100,000
Howmedica
1994 - 1999, Co-investigator
Remodelable bone cement augmentation of calcaneus fractures $ 30,000
Norian Corporation
1996 - 1999, Co-investigator
Intramedulary nailing in sub-trochanteric femur fractures $ 9,000
Biomet
1998 - 1999, Co-investigator
Compression screw for slipped capital femoral epiphysis $ 5,000
A.O. Synthes
1998 - 1999, Co-investigator
Evaluation of novel interbody fusion devices $ 25,000
Sofamor-Danek
1998 - 1999, Co-investigator
Biomechanics of anterior surgical approaches to the shoulder $ 11,000
Kerlan-Jobe Clinic
1998 - 1999, Co-investigator
Investigations into radiofrequency energy shortening of shoulder ligaments $ 2,000
Mitek Corporation
1998 - 1999, Co-investigator
Tension loss in spinal cable systems $ 9,000
Surgical Dynamics, Codman & Spinal Concepts
1998 - 1999, Principal Investigator
Pediatric anterior scoliosis system testing $ 9,000
Medtronic, Sofamor-Danek
1999 - 2000, Co-investigator
New systems testing $ 37,000
Bioplate
1999 - present, Principal Investigator
Fusion Study and New Instrumentation Testing $ 15,000
Curriculum Vitae
Thomas P. Hedman
Ph.D.
Page 7 of 32
Synthes
1999 - 2000, Co-Investigator
Intramedullary nailing in sub-trochanteric femur fractures $ 7,000
Biomet
1998 - 2002, Co-Investigator
New systems testing $ 19,000
Aesculap
2000 - 2001, Principal Investigator
New systems testing $ 10,000
Macropore
2000 - 2001, Principal Investigator
Biomechanical evaluation of the cervicothoracic junction $280,000
Sofamor-Danek, Synthes-Spine, Blackstone, Depuy/Acromed
2000 - 2003, Principal Investigator
Rat shoulder tendon study $ 9,000
James Tibone, M.D.
2001 - 2002, Principal Investigator
Opening/closing wedge osteotomy study $ 10,000
Congress Associates, Inc.
2001 - 2002, Principal Investigator
Biomechanical evaluation of knotless bone anchors $ 27,000
Opus Medical, Inc.
2001, Principal Investigator
Mucosal tissue tensile testing $ 1,250
USC Dept. Head and Neck Surgery, Research Division
2001, Co-investigator
Vascular tissue mechanical testing $ 3,000
Philogenesis
2001 - 2002, Principal Investigator
Biomechanical analysis of new materials for vertebroplasty $ 2,800
Interpore Cross International
20022003, Principal Investigator
Comparative testing of disc replacements $ 42,500
Spine Research Foundation
Curriculum Vitae
Thomas P. Hedman
Ph.D.
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20032004, Principal Investigator
Biomechanical evaluation of the cervicothoracic junction fixation $ 63,000
Blackstone Medical
2004 - 2005, Principal Investigator
Surgical Mesh 510k testing $ 4,000
Pegasus Biologics, Inc.
20042005, Principal Investigator
Rat-tail bending testing $ 17,500
Orthopeutics
20052006, Principal Investigator
Posterior decompression stability study Private Funding $ 1,650
Co-Investigator Funded
2006, Principal Investigator
Intervertebral joint restabilization post-discectomy $ 5,250
Orthopeutics
2006, Principal Investigator
Biomechanical evaluation of the Dynesys system $ 205,000
Zimmer Spine
20062007, Co-Investigator
NEXT In Vitro and In Vivo Preclinical Studies $2,956,000
Orthopeutics
2004Present, Principal Investigator
NEXT Product Development, FIM Studies $ 825,000
Intralink-Spine
2008Present, Principal Investigator
Rough Total: $7,650,000
F. Presentations
Invited Speaker
1. ASME-L.A. Chapter, An Introduction to Orthopaedic Biomechanics, October 28, 1999.
2. Wilson-Bost Interurban Orthopaedic Club Meeting, Biomechanical benefits of crosslink
Curriculum Vitae
Thomas P. Hedman
Ph.D.
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augmentation in spinal discs, April 25, 2003.
3. Tri-Service General Hospital, Biomechanical benefits of crosslinking in spinal discs,
Biomechanics of the thoracic spine, sternum and ribcage, Taipei, Taiwan, December 7,
2003.
Regional
1. Hedman, T.P.
Experimentally Derived Analytical Model of the Seated Lumbar Spine.
Presented at the Fourth Annual Orthopaedic Hospital Research Day, Los Angeles,
California,
May 22, 1995.
Thomas P. Hedman
Ph.D.
Presented at the University of Southern California, Department of Biomedical Engineering,
Los Angeles, California, November 2, 1999.
19. Hedman, T
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