Control Medical

CURRICULUM VITAE

NAME: John R. Dietz

CAMPUS ADDRESS: Department of Molecular Pharmacology

& Physiology

University of South Florida

College of Medicine, Box 8

Tampa, FL 33612

Phone: 813-***-****

FAX: 813-***-****

Email: abow8b@r.postjobfree.com

EDUCATION:

Degree Year Institution Major

B.S. 1973 University of Nebraska, Zoology Lincoln, Nebraska

Ph.D. 1979 University of Nebraska, Physiology

College of Medicine,

Omaha, Nebraska

Advisor: Dr. Irving H. Zucker

Post Doc 1979 82 University of Missouri, Physiology Columbia, Missouri

Advisor: Dr. James O. Davis

HONORS & AWARDS: NIH Hypertension training fellowship - 1979-82.

Citation Classic" - Current Contents 36: 9, 1993.

Fellow of the APS Circulation Section, 1992.

Distinguished Teacher Award - USF Medical Class of 1996.

Florida Teaching Incentive Program (TIP) Award, 1998.

Outstanding Contrib. to USF Coll. of Med. Teaching Award, 2000. USF President s Award for

Faculty Excellence, 2003.

Dean s Academic Performance Bonus, 2009, 2010.

College of Medicine Outstanding Teaching Award, 2011.

PROFESSIONAL SOCIETIES AND INSTITUTES:

American Physiological Society, 1978

USF Institute on Aging, 1996.

USF Cardiac Hormone Center, 1999.

International Society for Heart Research, 2003.

PROFESSIONAL EXPERIENCE:

Date Position and Duties

2006--present Professor, Department of Molecular Pharmacology & PhysiologyUniversity of South Florida, College of Medicine

.

1993--2006 Professor, Department of Physiology and BiophysicsUniversity of South Florida, College of Medicine

.

19871993Associate Professor, Department of Physiology,

University of South Florida, College of Medicine

.

19821987Assistant Professor, Department of Physiology,

University of South Florida, College of Medicine

.

19791982Postdoctoral fellow with Drs. James O. Davis and

Ronald H. Freeman: Department of Physiology,

University of Missouri, School of Medicine.

RESEARCH INTERESTS:

TEACHING EXPERIENCE:

Dates Subjects Student Population

University of Nebraska

1977 Cardiovascular Physiology Nursing

University of Missouri

1980 81 Fluids, acid base, Renal Undergraduate

19801981Physiology Laboratory Med I

University of South Florida

1982-presentRenal Physiology Med. I & Grad. Stud

.

1982-1995Renal Physiology Nursing

1989-1990Medical Physiology Course Director

1992-1995Acid-Base & Body Fluid Physiol. Med. I, Grad. &

Nursing

1996-presentAcid-Base & Body Fluid Physiol. Med. I, Grad

.

1993-present Small groups (All Physiology areas) Med. I

GRANTS

Duration Agency Title Total

Grants as

Principal Investigator:

7/836/85 American Heart, "Renin release from unclipped kidneys of $ 32,275

Florida Affiliate renal hypertensive rats.

7/85 9/86 American Heart, "Release of natriuretic factor $ 14,117

Florida Affiliate from a heart lung circuit"

12/86 11/89 NIH "Regulation of ANF release from a $145,000

heart lung preparation"

7/89 6/91 American Heart, "Modulation of Atrial Natriuretic Factor $ 56,500

Florida Affiliate by the Pituitary"

7/91-6/92American Heart, "The Role of ANF prohormone in the $ 40,000

Florida Affiliate Control of Blood Volume"

5/91-4/95NIH "Cardiac Peptides in the Control of Blood $334,000

Volume"

7/95-6/97American Heart, "Cardiac Hormones in Aging" $ 80,000

Florida Affiliate

7/97-6/99American Heart, "Cardiac Peptides in the Control $100,000

Florida Affiliate of Blood Volume"

7/97-6/99American Heart, "Cardiac Peptides in the Control $29,000

Florida Affiliate of Blood Volume" Pre-doctoral Fellow.

4/99-3/03 NIH "Secretion and Renal Effects $ 410,926

of Cardiac Peptides

7/07-6/08 CV Sig. Prog. Contribution of Cardiac Hormones $14,825

to Reduced Gastrointestinal Function

following Myocardial Infarction (MI)

GRANTS:

Grant Reviewer:

Peer Review Committee, American Heart Association, Florida Aff., 1991-1992, 1996-1998.

Peer Review Committee, American Heart Association, Southeast Consortium, 1998-2000.

Ad Hoc Reviewer: Veterans Administration, 1987, 1988, 1989, 1990, 1993, 1995.

Ad Hoc Reviewer: NSF, 1989; British Columbia Research Foundation, 1989, 1990.

CVSignature Grants

2007

Departmental Committees: Faculty Evaluations 1987, 1988, 1990, 1994, 1995, 1997, 1998

(Chair:1994 -Present); Faculty Search Committee, Chair - 1996; Faculty Search Committee,

1998; Medical Physiology 1988 1990 (Course Coordinator, 1990); Awards Committee

; Core Physiology Course

Coordinator:1993; Seminars: 1983, 1985, 1989, 1994-1996; APT Committee Chair, 1995-2010,

Faculty Search Committee, Chair 20062009

.

College Committees:

Media Center Oversight, 198485; Academic Status Committee, 1990-1992; Pharmacology Chair

Search Committee, 1990-1991; Graduate Committee, 1993-1994; Academic Computing Committee

Curriculum Evaluation - Computers- 2000-2002

;

Appointment, Promotion & Tenure

Signature Steering Committee

2007-Present ; Chair of CV Symposium Organizing

Committee,

2007-2009. Admissions Committee 2009-2012.

University Committees

:

Laboratory Animal Medicine Ethics Comm

National Committees:

American Physiological Society: Education Committee, 1996-1999: Initiated the APS Archive

of Digital Teaching Resources; APS Water & Electrolyte Homeostasis Committee:

Secretary/Treasurer, 1999-2002.

OTHER PROFESSIONAL EXPERIENCE (continued):

Dissertation Committees:

Dissertation Committee Member for Honors Student James Swoager (Biology), 1991.

Dissertation Committee Member for Kendall Morris Ph.D. (Physiology & Biophysics), 1993.

Dissertation Committee Member for Frank Cabell Ph.D. (Physiology & Biophysics), 1994.

Dissertation Committee Member for Ruby Parveen - M.S. (Physiology & Biophysics), 1994.

Dissertation Committee Member for Zhongzeng Li - Ph.D. (Physiology & Biophysics), 1999.

Major Professor for John P. Skvorak - Ph.D. (Physiology & Biophysics), 1996.

Outstanding Research Presentation, Annual Research Day, USF, HSC 1994.

Procter & Gamble Award from the American Physiology Society for the best abstract on

Water and Electrolyte Homeostasis at Experimental Biology 1995.

Outstanding Graduate Student Award, USF 1995.

Outstanding Dissertation Award, USF, 1997.

Dissertation Committee Member for Alton Thomas Ph.D. (Anatomy), 1999.

Dissertation Committee Member for Xuedong Chi - Ph.D. (Physiology & Biophysics), 1999.

Major Professor for Ping Lai M.S. (Physiology & Biophysics), 1999.

Dissertation Committee Member for Lavanya Balasubramanian (MPP), Ph.D. 2007.

Dissertation Committee Member for Stephanie Wolf (MPP), Ph.D. expected 2008.

Dissertation Committee Member for McKenzie Ott (MPP), Ph.D. 2010.

Major Professor for Anteneh Addisu - (Molecular Pharmacology & Physiology), Ph.D. 2008.

Awarded IGERT SKINS Fellowship: 2005-2007.

Dissertation Committee Member for Drew Ride (MPP), Ph.D. exp 2012.

Postdoctoral Fellow: Sookjeong Lee, Ph.D. 2001-2003.

PUBLICATIONS (* indicates invited submission)

Gilmore, JP, DIETZ, JR, Gilmore, C, and Zucker, IH. evidence for a chloride pump in the

salt gland of the goose. Comp Biochem Physiol 56A: 121 126, 1977.

Gilmore, JP, Gilmore, C, DIETZ, JR, and Zucker, IH. influence of chronic cervical

vagotomy on salt gland secretion in the goose. Comp Biochem Physiol, 57A: 119 121, 1977.

Zucker, IH, Gilmore, C, DIETZ, JR, & Gilmore, JP. Effect of volume expansion and

veratrine on salt gland secretion in the goose. Am J Physiol 232(5): R185 R189, 1977.

DIETZ, JR, Zucker, IH, and Gilmore, JP. hematocrit as an index of changes in plasma

volume in conscious dogs. Experientia 35: 1064 1065, 1979.

Seymour, A.A., Davis, J.O., Freeman, R.H., Echtenkamp, S.F., and DIETZ, J.R.

adrenergically induced renin release in conscious indomethacin treated dogs and rats. Am J

Physiol 240(6): F515 F521, 1981.

Echtenkamp, SF, Davis, JO, DeForrest, JM, Rowe, BP, Freeman, RH, Seymour, AA, & DIETZ,

JR. Effects of indomethacin, renal denervation and propranolol on renin release in dogs

with chronic thoracic caval constriction. Circ Res 49: 492 500, 1981.

DIETZ, JR, Davis, JO DeForrest, JM, Freeman, RH, Echtenkamp, SF, and Seymour, AA. Effects

of indomethacin in dogs with acute and chronic renovascular hypertension. Am J Physiol

240(4): H533 H538, 1981.

* Davis, JO, Freeman, RH, Echtenkamp, SF and DIETZ, JR. An update on the control of renin

release. in: Heterogeneity of renin and renin substrate. Elsevier North Holland, Inc. M.

Sambhi, ed. 1981.

DIETZ, JR, Davis, JO, Freeman, RH, Echtenkamp, SF, and Villarreal, D. failure of

indomethacin to inhibit saralasin stimulated plasma renin activity in conscious dogs with

mild sodium depletion. Proc Soc Exp Biol Med 167: 567 571, 1981.

Villarreal, D, Freeman, RH, Davis, JO, DIETZ, JR, and Echtenkamp, SF. Effects of sodium

chloride on prostacyclin stimulated renin release in dogs with filtering and non filtering

kidneys. Proc Soc Exp Biol Med 171(1):

Physiol 234(4): 584 H589, 1982.

DIETZ, JR, Bie, P, Gilmore, JP, Share, L, and Zucker, IH. The relation between carotid

solute concentration and renal water excretion in conscious dogs. Acta Physiol Scand

114:45 51, 1982.

Freeman, RH, Davis, JO, DIETZ, JR, Villarreal, D, Seymour, AA, Echtenkamp, SF. Renal

prostaglandins and the control of renin release. Hypertension, Sup. II 4(3): II106 II112,

1982.

Villarreal, D, Davis, JO, Freeman, RH, DIETZ, JR, Luger, AM. A denervated non filtering

kidney model preparation in the rat: a model for the study of renin release. Proc Soc BiolMed 173(1): 140 147, 1983.

DIETZ, JR, Davis, JO, Freeman, RH, Villarreal, D, Echtenkamp, SF. Effects of intrarenal

infusion of calcium entry blockers in anesthetized dogs. Hypertension 5(4): 482 488, 1983.

Villarreal, D, Davis, JO, Freeman, RH, DIETZ, JR, Echtenkamp, SF. Effects of indomethacin

in conscious dogs with experimental high output heart failure. Am J Physiol 245(6): H942

H946, 1983.

Echtenkamp, SF, Davis, JO, Freeman, RH, Sweet, WD, DIETZ, JR. Splanchnic and renal

contributions to circulatory homeostasis in the sodium depleted conscious dog. Am J

Physiol 245: H573 H579, 1983.

DIETZ, J.R. Release of natriuretic factor from a rat heart lung preparation by atrial

distention. Am J Physiol 247: R1093 R1096, 1984.

Note: This is a classic paper in the field and has been cited over 500 times.

Villarreal, D, Davis, JO, Freeman, RH, Sweet, WD, DIETZ, JR. Effects of meclofenamate on

the renin response to aortic constriction in the rat. Am J Physiol 247(3): R546 R550,

1984.

DIETZ, JR. Renin release from nonclipped kidneys of 2K 1C hypertensive rats. Proc Soc Exp

Biol Med 179: 147 154, 1985.

Anderson, DE, Gomez Sanchez, C, DIETZ, JR. Suppression of plasma renin and aldosterone in

stress salt hypertension in the dog. Am J Physiol 251: R181 R186, 1986.

DIETZ, JR. Effects of a calcium channel agonist on renin release from perfused rat

kidneys. Renal Physiol. 9: 279 286, 1986.

Anderson, DE, DIETZ, JR, and Murphy, P. Behavioral hypertension in sodium loaded dogs

accompanied by sodium but not water retention. J Hypertension 5: 99 105, 1987.

DIETZ, JR. Control of atrial natriuretic factor release from a rat heart lung

preparation. Am J Physiol 252: R498 R502, 1987.

Rao, P, Cavanagh, D, DIETZ, JR, Marsden, KA, O'Brien, WF, Spaziani E. Dose dependent

effects of prostaglandin D2 on hemodynamics, renal function and blood gas analyses. Am J

Obstet Gynecol 156(4): 843 851, 1987.

Nazian, J, DIETZ, JR. Reproductive changes during the early stages of chronic renal

insufficiency in the male rat. Biol Reprod 37: 105 111, 1987.

DIETZ, JR. The effects of angiotensin II and ADH on the secretion of atrial natriuretic

factor. Proc Soc Exp Biol Med 187(3): 366 369, 1988.

Ramirez, G, Bittle, P, Hammond, MD, Ayers, CW, DIETZ, JR, Colice, GL. Regulation of

aldosterone secretion during hypoxemia at sea level and moderate high altitude. J Clin

Endocrinol Metab 67: 1162, 1988.

DIETZ, JR, Nazian, SJ. Release of atrial natriuretic factor in hypophysectomized rats. Am

J Physiol 255: R534 R538, 1989.

Nazian, SJ, DIETZ, JR, Rowland, MD. Pituitary responses to LHRH during chronic renal

insufficiency in the male rat. J Androl 10(3): 174 179, 1989.

DIETZ, JR. Nazian, SJ. Studies on the role of the pituitary in the control of atrial

natriuretic factor secretion and sodium excretion. Proc Soc Exp Biol Med 194(3): 231-239,

1990.

Baker, CH, Sutton, ET, Zhou, Z, DIETZ, JR. Micro vascular vasopressin effects during

endotoxic shock in the rat. Circ Shock 30(2): 81-95, 1990.

* DIETZ, JR, Gilmore, JP. The role of renal afferent nerves in circulatory control. In:

Reflex Control of the Circulation. Eds: IH Zucker and JP Gilmore. CRC Press Inc, Boca

Raton, FL 1991.

Colice, G, Yen, S, Ramirez, G, DIETZ, JR, Ou, LC. Acute hypoxia-induced diuresis in rats.

Aviat Space Environ. Med 62(6): 551-554, 1991.

DIETZ, JR, Nazian, SJ, Vesely, DL. Release of ANF, proANF 1-98, and proANF 31-67 from

isolated rat atria by atrial distension. Am J Physiol 260: H1774-H1778, 1991.

Baker, CH, Sutton, ET, DIETZ, JR. Endotoxin alterations of muscle microvascular renin-

angiotensin responses. Circ Shock 36: 224-230, 1992.

Ramirez, G, Saba, SR, DIETZ, JR., Vesely, DL. Immunocytochemical localization of proANF 1-

30, proANF 31-67 and atrial natriuretic factor (ANF) in the kidney. Kidney Intern 41(2):

334-341, 1992.

DIETZ, JR, Vesely, DL, Nazian, SJ. The effect of changes in sodium intake on atrial

natriuretic factor (ANF) and N-terminal ANF prohormones in the rat. Proc Soc Exp Biol Med

200(1): 44-48, 1992.

* DIETZ, JR. The role of atrial natriuretic factor in salt and water homeostasis. J FL

Med Assoc 79(8): 569-571, 1992.

Ramirez, G, Hammond, M, Agosti, SJ, Bittle, PA, DIETZ, JR, Colice, GL. Effects of

hypoxemia at sea level and high altitude on sodium excretion and hormonal levels. Aviat

Space Environ Med 63: 891-898, 1992.

* DIETZ, JR. Release of atrial natriuretic factor by atrial distension. Current Contents

(Citation Classic). 36(38): 9, 1993 (see # 18).

http://garfield.library.upenn.edu/classics1993/A1993LV33700002.pdf

Colice, G L, Lawrason, J, Munsef, A, Bittle, P, DIETZ, JR.,Ramirez, G. Hormonal response

to exercise in high altitude natives and COPD patients. Aviat Space Environ Med 64: 512-

516, 1993.

Ramirez G, Bittle, PA, Agosti, SJ, DIETZ, JR, Colice, GL. Salt loading test in a

population adapted to moderately high altitude living (3,000 m). Aviat Space Enviorn Med

64: 831-838, 1993.

Vesely, DL, Douglass, MA, DIETZ, JR, Giordono, AT, McCormick, MT, Rodriguez-Paz, G.,

Shocken, DD. Negative feedback of atrial natriuretic peptides. J Clin Endocrinol Met.

78(5): 1128-1134, 1994.

Vesely, DL, Douglass, MA, DIETZ, JR, Gower, WR, McCormick, MT, Rodriguez-Paz, G.,

Shocken, DD. Three peptides from the atrial natriuretic factor prohormone amino terminus

lower blood pressure and produce a diuresis, natriuresis and/or kaliuresis in humans.

Circulation 90(3): 1129-1140, 1994.

DIETZ, JR, Vesely, DL, Nazian, SJ. Possible mechanisms involved in the natriuretic

response to ANF and proANF 31-67 in the rat. Clin Exp Pharmacol Physiol 21(8): 599-606,

1994.

Gower, WR, DIETZ, JR, Vesely, DL, Finley, CL, Skolnick, KA, Fabri, PJ, Cooper, DR,

Chalfant, CE. Atrial natriuretic peptide gene expression in the rat gastrointestinal

tract. Biochem Biophys Res Commun 202(1): 562-570, 1994.

Rao, PS, Cavanagh, D, DIETZ, JR. Renal effects of intermittent versus continuous infusion

of ibuprofen in the primate. Prostagland Leukotr & Essent Fatty Acids 51: 249-256, 1994.

Rabb, H, Mendiola, C, DIETZ, JR, Saba, SR, Issekutz, TB, Abanilla, F, Bonventre, JV,

Ramirez, G. Role of CD11a and CD11b in ischemic acute renal failure in rats. AJP 267:

F1052-F1058, 1994.

DIETZ, JR, Vesely, DL, Gower WR, Nazian, S. Secretion and renal effects of atrial

natriuretic factor and ANF prohormone peptides in the rat. Clin Exp Pharmacol Physiol 22:

115-120, 1995.

*Habibullah, AA, Villarreal, D, Freeman, RH, DIETZ, JR, Vesely, DL, Simmons, JC. Atrial

natriuretic peptide fragments in dogs with experimental heart failure. Clin Exp Pharmacol

Physiol 22: 130-135, 1995.

*DIETZ, JR, Villarreal, D. Symposium Introduction: Physiological functions of atrial

natriuretic factor prohormone peptides. Clin Exp Pharmacol Physiol 22: 107, 1995.

Rabb, H, Mendiola, CC, Saba, SR, DIETZ, JR, Smith, CW, Bonventre, JV, Ramirez, G.

Antibodies to ICAM-1 protect kidneys in severe ischemic reperfusion injury. Biochem

Biophys Res Comm 211(1): 67-73, 1995.

Skvorak, JP, Nazian, SJ, DIETZ, JR. Endothelin acts as a paracrine regulator of stretch

induced atrial natriuretic peptide release. Am J Physiol 269: R1093-R1098, 1995.

Ramirez, G, Pineda, DO, Bittle, PA, Agosti, SJ, Rabb, HA, DIETZ, JR. Salt excretory

capacity in natives adapted to moderate high altitude living after acute mobilization to

sea level. Aviat Space Enviorn Med 66: 1063-1070, 1995.

Colice, GL, Lee, YJ, Chen, J, Du, HK, Ramirez, G, DIETZ, JR, Ou, LC Susceptibility to

high-altitude pulmonary edema in Madison and Hilltop Rats. I. Ventilation and Fluid

Balance. J Appl Physiol 78 (6): 2279-2285, 1995.

Skvorak, JP, Sutton, ET, Rao, PS, DIETZ, JR. Mechanism of anoxia-induced atrial

natriuretic peptide release in the isolated perfused rat atria. Am J Physiol 271: R237-

R243, 1996.

* DIETZ, JR. The Role of Atrial Natriuretic Peptides in Cardiovascular Homeostasis.

Chonnam Journal of Medical Sciences: Proceedings of the International Symposium on

Ischemic Cardiovascular Diseases 9(1): 83-87, 1996.

Pollack, JA, Skvorak, JP, Landon, CS, Nazian, SJ, DIETZ, JR. alterations in atrial

natriuretic peptide (ANP) secretion and renal effects in aging. Journal of Gerontology:

Biomedical Sciences 52A(4): B196-B202, 1997.

Skvorak, JP, DIETZ, JR. endothelin and nitric oxide (no) interact to regulate stretch-

induced ANP secretion. Am J Physiol 273: R301-R306, 1997.

Rao, PS, Cavanagh, D, Graham, LB, DIETZ, JR, Florica, JV, Hoffman, MS. Endotoxin induced

atrial natriuretic factor release: in vivo and in vitro studies. A J Obs Gyn 179(1): 21-

27, 1998.

Nazian, SJ, Landon, CS, DIETZ, JR. Alterations in the opioid control of LHRH release from

hypothalami isolated from aged male rats. Journal of Gerontology: Biomedical Sciences 53A:

B191-B195, 1998.

Vesely, DL, DIETZ, JR, Parks, JR, Baig, M., McCormick, MT, Cintron, G., Schocken, DD.

Vessel dilator enhances sodium and water excretion and has beneficial hemodynamic effects

is persons with congestive heart failure. Circulation 98: 323-329, 1998.

* DIETZ, JR, Gower WR, Vesely, DL, Nazian, SJ, Landon, CS, Skvorak, JP. Molecular species

of the atrial natriuretic peptide (ANP) prohormone secreted by isolated rat atria. In:

Atrial Natriuretic Peptides. D L Vesely, Ed., Research Signpost, India 119-127, 1999.

Vesely, DL, Gower, WR, DIETZ, JR, Overton, LC, Antwi, EK, Farese, RV. Elevated atrial

natriuretic peptides and early renal failure in type II diabetic Goto-Kakizaki rats.

Metabolism 48: 771-778, 1999.

Vesely, DL, DIETZ, JR, Parks, Baig, Antwi, E, Overton, RA, McCormick, MT, Cintron, G,

Schocken, DD. Comparison of vessel dilator and long acting natriuretic peptide in the

treatment of heart failure. Am Heart J 138(3): 625-632, 2000.

Gower, WR, Salhab, KF, Foulis, WL, Pillai, N, Vesely, DL, Fabri, PJ, Bundy, JR, DIETZ,

JR. Regulation of atrial natriuretic peptide gene expression in gastric antrum by fasting.

Am J Physiol 278: R770-R780, 2000.

Lai, P, Nazian, SJ, Gower, WR, Landon, CS, DIETZ, JR. Increased bioactivity of rat atrial

extracts: Relation to aging and blood pressure regulation. J Gerontol: Bio Sci 55A (8):

B390-B395, 2000.

DIETZ, JR, Scott, DY, Landon, CS, Nazian, SJ. Evidence supporting a physiological role

for proANP 1-30 in the regulation of renal excretion. Am J Physiol 280: R1510-R1517, 2001.

Nasser, A, DIETZ, JR, Siddique, M, Patel, H, Khan, N, Antwi, EK, San-Miguel, GI,

McCormick, MT, Schocken, DD, Vesely, DL. Kaliuretic peptide enhances sodium and water

excretion in persons with congestive heart failure. Am J Cardiol 88(1): 23-29, 2001.

Gower, WR, DIETZ, JR, McCuen, CS, Fabri, PJ, Lerner, EA, Schubert, ML. Regulation of

atrial natriuretic peptide secretion by cholinergic and PACAP sensitive neurons in the

antrum of the stomach. Am J Physiol (Gastrointest Liver Physiol)284 (1): G68-G74, 2003.

Gower, WR, McCuen, CS, Arimura, A, Coy, DA, DIETZ, JR, Landon, CS, Schubert, M.

Reciprocal paracrine pathways link atrial natriuretic peptide and somatostatin secretion

in the antrum of the stomach. Regulatory Peptides 110(2): 101-106, 2003.

DIETZ, JR, Vesely, DL, Gower, WR, Landon, CS, Lee, S, Nazian, SJ. Neutralization of

proANP 1-30 exacerbates hypertension in the spontaneously hypertensive rat (SHR). Clin Exp

Pharmacol Physiol 30 (9): 627-31, 2003.

Lee, SJ, Landon, CS, Nazian, SJ, DIETZ, JR. Role of CYP450-arachidonate metabolites in

endothelin signaling of cardiac hormone secretion in heart. Am J Physiol 286(5): R888-

R893, 2004.

Patel, H, DIETZ, JR, Owen, A, San Miguel, G, McCormick, MT, Schocken, DD, Vesely, DL

combined treatment with vessel dilator and kaliuretic hormone in persons with congestive

heart failure. Exp Biol Med 229: 521-527, 2004.

DIETZ, JR, Landon, CS, Nazian, SJ, Vesely, DL, Gower, WR. Effects of cardiac hormones on

arterial pressure and sodium excretion in NPRA knockout mice. Exp Biol Med 229: 813-818,

2004.

*DIETZ, JR. Mechanisms of Atrial Natriuretic Peptide Secretion from the Atrium.

Cardiovascular Research, 68(1): 8-17, 2005.

Wall SM, Knepper MA, Hassell KA, Fischer MP, Shodeinde A, Shin W, Pham TD, Meyer JW,

Lorenz JN, Beierwaltes WH, DIETZ JR, Shull GE, Kim YH. Hypotension in NKCC1 null mice:

role of the kidneys. Am J Physiol 290(2): F409-16, 2006.

Addisu A, Gower WR, Landon CS, DIETZ JR. B-Type Natriuretic Peptide Decreases Gastric

Emptying and Absorption. Exp Biol Med 233(4): 475-482, 2008.

Vinitha JA, Harbaugh CM, DIETZ JR, Fenton, RA Kim SM, Castrop H, Schnermann J. Knepper,

MA Chou, C Anderson, SA. Magnetic resonance imaging of urea transporter knockout mice

reveals two distinct types of renal pelvic abnormalities. Kidney International 74: 1202-

1208, 2008.

*Kshatriya, K, Reams, GP, Spear, RM, Freeman, RH, DIETZ, JR, Villarreal, D. Obesity-

Hypertension: The Emerging Role of Leptin in Renal and Cardiovascular Dyshomeostasis.

Current Opinion in Nephrology and Hypertension 19(1): 72-78, 2010.

DIETZ, JR. Using Willie s Acid-Base Box for Blood Gas Analysis. Advances in Physiology

Education. 35 (4): 454-455, 2011.

Addisu, A, Gower, WR, Serrano, M, Villarreal, D and JR DIETZ. Heart Failure Mice Exhibit

Decreased Gastric Emptying and Intestinal Absorption. Exp Biol Med 236 (12): 1454-1460,

2011.

DIETZ, JR and Stevenson, FT. Active Learning in a Large Medical Classroom Setting for

Teaching Renal Physiology. Advances in Physiology Education. 35 (4): 456-459, 2011.

Other Scholarly Publications: COMPUTER TEACHING SOFTWARE: Developed four teaching related

computer programs:

Glomerular Filtration

Body Fluids

Tubular Osmolality

Transport Maximum

These programs were used in our medical physiology course and were purchased by over 50

universities. The software was reviewed in BIOSYS 43(1): 1992.

World Wide Web Resources

(Peer reviewed)

Dietz, JR & Dietz CG. Weakness and Hypotension . Case History for the American

Physiological Society Archive of Teaching Resources. Adv. in Physiol. Ed. 27: 165, 2003

(Object #3654). http://www.apsarchive.org/resource.cfm?submissionID=3654

Dietz, JR & Dietz CG. Hyponatremia . Case History for the American Physiological

Society Archive of Teaching Resources. Adv. in Physiol. Ed. 27: 163, 2003 (Object #3656).

http://www.apsarchive.org/resource.cfm?submissionID=3656

Dietz, JR. & Dietz CG. "Acidosis: Metabolic and Respiratory". Case History for the

American Physiological Society Archive of Teaching Resources. Adv. in Physiol. Ed. 27:

165, 2003 (Object #192). http://www.apsarchive.org/resource.cfm?submissionID=192

Dietz, JR. "Physiology of the Kidneys, Body Fluids and Acid-Base Balance": Sets of

lecture slides, American Physiological Society Archive of Teaching Resource. Adv. in

Physiol. Ed. 27: 163, 2003 (Object #57).

http://www.apsarchive.org/resource.cfm?submissionID=57

Dietz, JR & Dietz CG. Polyuria and Polydypsia . Case History for the American

Physiological Society Archive of Teaching Resources. Adv. in Physiol. Ed. 27: 166, 2003

(Object #3657). http://www.apsarchive.org/resource.cfm?submissionID=3657

Dietz, JR & Dietz CG. Hypertension . Case History for the American Physiological Society

Archive of Teaching Resources. Adv. in Physiol. Ed. 27: 165, 2003 (Object #3659).

http://www.apsarchive.org/resource.cfm?submissionID=3659

Dietz, JR & Dietz CG. "Acidosis: Respiratory". Case History for the American

Physiological Society Archive of Teaching Resources. Adv. in Physiol. Ed. 27: 166, 2003

(Object #197). http://www.apsarchive.org/resource.cfm?submissionID=197

Dietz, JR & Preuss C. "Fluid Retention with the MAZE procedure". Case History for the

American Physiological Society Archive of Teaching Resources, 2010 (object 3814)

http://www.apsarchive.org/resource.cfm?submissionID=3814

Dietz, JR. "Using Willie s Acid-Base Box to Analyze Arterial Blood Gases". Learning

method for the American Physiological Society Archive of Teaching Resources,

2011(object925) http://www.apsarchive.org/resource.cfm?submissionID=4925

Dietz, JR and Panzarino V. Active Learning in a Large Classroom for Teaching Physiology:

Acid Base Cases . Learning method for the American Physiological Society Archive of

Teaching Resources, 2011 (object 5701).

http://www.apsarchive.org/resource.cfm?submissionID=5701

Preuss C & Dietz, JR. Hypertension Case History for the American Physiological Society

Archive of Teaching Resources, 2011(object 5101).

http://www.apsarchive.org/resource.cfm?submissionID=5101

Dietz, JR:

This Laboratory is studying a group of Cardiac Hormones called natriuretic peptides

because they are hormones secreted by the heart that increase the excretion of sodium (Na)

by the kidneys (uretic).

These hormones are part of a naturally occurring mechanism that is important in

regulating blood volume and blood pressure.

Salt Intake ( Blood Volume Expansion and Stretch of the Atria ( atrial natriuretic

peptide (ANP) Secretion.

ANP increases salt and water excretion to reduce blood volume and blood pressure.

ANP also directly dilates blood vessels which helps to lower blood pressure.

Work in this area over the past 20 years has already resulted in new drugs to treat

hypertension and heart failure.

ANP is normally degraded in the kidneys by an enzyme (NEP) which breaks its peptide ring

structure, making it inactive.

Drugs which inhibit NEP cause ANP in the plasma to increase, thus augmenting ANP s blood

pressure lowering capacity.

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