Medical Vice President

February ****

Curriculum Vitae

Peter S. Kim

Merck Research Laboratories Tel: 267-***-****

Merck & Co., Inc. Fax: 267-***-****

UG-4CD01, E-mail: peter_kim@merck.com351 North Sumneytown Pike

North Wales, PA 19454

Professional Experience:

2008-presentExecutive Vice President, Merck & Co., Inc

.

2003-presentPresident, Merck Research Laboratories

2001-2002Executive Vice President, Research and Development,

Merck Research Laboratories

1999-2001Associate Head, Department of Biology, M.I.T

.

1997-2001Investigator, Howard Hughes Medical Institute

1995-2001 Professor of Biology, M.I.T

.

1992-2001Member, Whitehead Institute for Biomedical Research

1993-1997Associate Investigator, Howard Hughes Medical Institute

1992-1995Associate Professor of Biology, M.I.T

.

1990-1993Assistant Investigator, Howard Hughes Medical Institute

1988-1992Assistant Professor of Biology, M.I.T

.

1988-1992Associate Member,

Whitehead Institute for Biomedical Research

1985-1988Whitehead Fellow, Whitehead Institute for Biomedical Research

Education:

1985 Ph.D., Biochemistry, Stanford University.

Medical Scientist Training Program Fellow.

1979 A.B., Cornell University.

Magna Cum Laude in Chemistry with Distinction.

Board Memberships and Other Affiliations:

2003-2009 Member, Board of Directors, Fox Chase Cancer Center

2005-present Member, Board of Directors, Whitehead Institute for Biomedical Research

2009-present Member, Board of Trustees, Alfred P. Sloan Foundation

Peter S. Kim 2

Elected Memberships:

2008 Fellow, American Academy of Arts and Sciences.

2000 Member, Institute of Medicine, National Academy of Sciences.

1999 Fellow, American Association for the Advancement of Science.

1999 Fellow, Biophysical Society.

1999 Member, Korean Academy of Science and Technology.

1997 Fellow, American Academy of Microbiology.

1997 Member, National Academy of Sciences.

Service:

2009-present Council, Global HIV Vaccine Enterprise

2008-2012 HARC (HIV Accessory and Regulatory Complexes) Scientific Advisory

Board, University of California, San Francisco

2008-present External Life Sciences Advisory Council, Cornell University

2006-2008 Oversight Committee, Division on Earth and Life Studies,

The National Academies

2006-2011 Council, Institute of Medicine, National Academy of Sciences

2004-2012MIT Corporation Visiting Committee, Department of Biology,

MIT

2004-presentAdvisory Council, Lewis Sigler Institute for Integrative Genomics,

Princeton University

1997-2001AIDS Vaccine Research Committee, National Institutes of Health.

1997-2001 Biology Subcommittee, Korea Institute for Advanced Studies.

1998-1999 IOM Committee for the Assessment of Future Needs for the Variola

(Smallpox) Virus, Institute of Medicine, National Academy of Sciences.

1998 Co-Chair, Annual Meeting, The Protein Society.

1995-1998Council, Biophysical Society

.

1993-1995 Nominating Committee, American Peptide Society.

1990-1993Nominating Committee, The Protein Society.

Editorial Advisory Boards

:

1998-2001Editorial Board, Current Opinion in Chemical Biology.

1995-2001Editor, Advances in Protein Chemistry.

1994-2001Editorial Board,

Molecules and Cells.

1989-2001Editorial Board,

Current Opinion in Structural Biology.

1998-2000Editorial Board, Biochemistry

.

1991-1999Associate Editor,

Cell.

1995-1998Editorial Board,

Folding & Design.

Editorial Board, Protein Engineering.

Awards:

1999 Hans Neurath Award, The Protein Society.

1999 Moosa Award, Biochemical Society of the Republic of Korea.

1998 Ho-Am Prize for Basic Science, The Samsung Foundation.

1995 Mack Award, Ohio State University.

1995 Pfizer Animal Health Award, University of Nebraska.

1994 Ilchun Award, Korean Society of Molecular Biology.

2

Peter S. Kim - 3

Awards (continued):

1994 DuPont Merck Young Investigator Award, The Protein Society.

1994 Eli Lilly Award in Biological Chemistry, American Chemical Society.

1993 NAS Award in Molecular Biology, National Academy of Sciences.

1990-1994 Pew Scholar in the Biomedical Sciences, Pew Charitable Trust.

1990-1992 Rita Allen Scholar, Rita Allen Foundation.

1989 Excellence in Chemistry Award, ICI Pharmaceuticals.

1989 Walter J. Johnson Prize in Molecular Biology, Journal of Molecular Biology.

1987-1988 Leonard Skeggs Chair for Whitehead Fellows.

Lectureships:

2006 Presidents Circle, National Academies

2004 Opening Plenary Lecture, American Society for Cell Biology

2002 Harvey Lecture, The Harvey Society

2000 William W. Brockman Memorial Lecture, University of Michigan.

1995 Denkewalter Lecture, Loyola University of Chicago.

1994 Burroughs Wellcome Fund Visiting Professorship, University of Colorado.

1993 Julius Stieglitz Lecture, University of Chicago.

1993 Joseph F. Foster Memorial Lecture, Purdue University.

1991 Henry Bull Lecture in Protein Chemistry, University of Iowa.

1991 Dean's Distinguished Lecture, University of Colorado.

2000 State of the Art Lecture, 7th Conference on Retroviruses and Opportunistic

Infections.

1998 Irving S. Sigal Lecture, Merck Research Laboratories.

1998 Karl Beyer Visiting Professorship, University of Wisconsin.

1997 State of the Art Lecture, International Congress of Biochemistry and

Molecular Biology.

1996 Inauguration Symposium Lecture, Korea Institute for Advanced Studies.

1995 DeWitt Stetten, Jr. Lecture, NIGMS, National Institutes of Health.

Personal Profile: Born April, 1958. Married, three children.

Publications:

Robert L. Baldwin.

Nature (1984) 307: 329-334.

A Helix Stop Signal in the Isolated S-Peptide of Ribonuclease A.

10. Kevin R. Shoemaker

Peter S. Kim, David N. Brems, Susan Marqusee, Eunice J. York,

Irwin M. Chaiken

John M. Stewart and Robert L. Baldwin.

Proc. Natl. Acad. Sci. USA (1985) 82:

56. Brenda A. Schulman and Peter S. Kim.

Protein Science (1994) 3: 2226-2232.

Hydrogen Exchange in BPTI Variants that Do Not Share a Common Disulfide Bond.

57. Jonathan P. Staley and Peter S. Kim.

Protein Science (1994) 3: 1822-1832.

Formation of a Native-Like Subdomain in a Partially Folded Intermediate of Bovine

Pancreatic Trypsin Inhibitor.

58. Bonnie Berger, David B. Wilson, Ethan Wolf, Theodore Tonchev, Maria Milla and

Peter S. Kim.

Proc. Natl. Acad. Sci. USA (1995) 92: 8259-8263.

Predicting Coiled Coils by Use of Pairwise Residue Correlations.

59. Stephen C. Blacklow, Min Lu and Peter S. Kim.

Biochemistry (1995) 34: 149**-*****.

A Trimeric Subdomain of the Simian Immunodeficiency Virus Envelope Glycoprotein.

60. Paula J. Booth, Sabine L. Flitsch, Lawrence J. Stern, Duncan A. Greenhalgh, Peter S.

Kim

and H. Gobind Khorana.

Nature Structural Biology (1995) 2: 139-143.

Intermediates in the Folding of the Membrane Protein Bacteriorhodopsin.

61. Michal Dadlez and Peter S. Kim.

Nature Structural Biology (1995) 2: 674-679.

A Third Native One-Disulfide Intermediate in the Folding of Bovine Pancreatic Trypsin

Inhibitor.

62. Deborah Fass and Peter S. Kim.

Current Biology (1995) 5: 1377-1383.

Dissection of a Retrovirus Envelope Protein Reveals Structural Similarity to Influenza

Hemagglutinin.

63. Pehr B. Harbury, Bruce Tidor and Peter S. Kim.

Proc. Natl. Acad. Sci. USA (1995) 92: 8408-8412.

Repacking Protein Cores with Backbone Freedom: Structure Prediction for Coiled Coils.

64. Min Lu, Stephen C. Blacklow and Peter S. Kim.

Nature Structural Biology (1995) 2: 1075-1082.

110. John R. S. Newman, Ethan Wolf and Peter S. Kim.

Proc. Natl. Acad. Sci. USA (2000) 97: 132**-*****.

A Computationally Directed Screen Identifying Interacting Coiled Coils from

Saccharomyces cerevisiae.

111. Itay Rousso, Mark B. Mixon, Benjamin K. Chen and Peter S. Kim.

Proc. Natl. Acad. Sci. USA (2000) 97: 13523

-13525.

Palmitoylation of the HIV-1 Envelope Glycoprotein is Critical for Viral Infectivity.

112. Xun Zhao, Mona Singh, Vladimir N. Malashkevich and Peter S. Kim.

Proc. Natl. Acad. Sci. USA (2000) 97: 141**-*****.

Structural Characterization of the Human Respiratory Syncytial Virus Fusion Protein Core.

113. David L. Akey, Vladimir N. Malashkevich and Peter S. Kim.

Biochemistry (2001) Vol. 40: 6352-6360.

Buried Polar Residues in Coiled-Coil Interfaces.

114. Debra M. Eckert and Peter S. Kim.

Annu. Rev. Biochem. (2001) 70: 777-810.

Mechanisms of Viral Membrane Fusion and Its Inhibition.

115. Michael J. Root

Michael S. Kay and Peter S. Kim.

Science (2001) 291: 884-888.

Protein Design of an HIV-1 Entry Inhibitor.

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Peter S. Kim

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116. Mona Singh and Peter S. Kim.

th

Proc. 5 Ann. Int. Conf. Comp. Mol. Biol. (2001) 279-286.

Towards Predicting Coiled-Coil Protein Interactions.

117. Vladimir N. Malashkevich, Mona Singh and Peter S. Kim.

Proc. Natl. Acad. Sci. USA (2001)

98: 8502-8506

The Trimer-of-Hairpins Motif in Membrane Fusion: Visna Virus.

118. Samuel K. Sia and Peter S. Kim.

Biochemistry (2001) 40: 8981-8989

A Designed Protein with Packing Between Left-Handed and Right-Handed Helices.

119. Benjamin K. Chen, Itay Rousso, Sung Shim and Peter S. Kim

Proc. Natl. Acad. Sci. (2001) 98: 152**-*****

Efficient Assembly of an HIV-1/MLV Gag-Chimeric Virus in Murine Cells

120. Debra M. Eckert and Peter S. Kim

Proc. Natl. Acad. Sci. USA (2001) 98: 111**-*****

Design of Potent Inhibitors of HIV-1 Entry from the pg41 N-peptide Region

121. Philip Bradley, Peter S. Kim, and Bonnie Berger

Proc. Natl. Acad. Sci. USA (2002) 99: 8500-8505.

TRIOLOGY: Discovery of Sequence-Structure Patterns Across Diverse Proteins

122. Yoshihisa Hagihara and Peter S. Kim

Proc. Natl. Acad. Sci. USA (2002) 99: 6619-6624

Toward Development of a Screen to Identify Randomly Encoded, Foldable Sequences

123. Samuel K. Sia, Peter A. Carr, Andrea G. Cochran, Vladimir N. Malashkevich andPeter S. Kim

Proc. Natl. Acad. Sci. USA (2002) 99: 146**-*****

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