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Biometry Research Group
Curriculum Vitae forGrant Izmirlian
PhD
Mathematical Statistician
US Mail Address
Biometry Research Group, DCP
National Cancer Institute
Executive Plaza North, Room 31316130 Executive Blvd, MSC 7354
Bethesda, MD 20892-7354 Shipping Address
Biometry Research Group, DCP
National Cancer Institute
6130 Executive Blvd, Room 3131
Rockville, MD 20852
Phone: 301-***-**** Fax: 301-***-****
E-mail: *********@***.***
Professional Experience
Education
Awards and Honors
Memberships
Referee Services
Editorial Board
Research Interests
Bibliography
Peer-Reviewed Journals
Published Abstracts
Professional Experience
08/1999-presentMathematical Statistician
Biometry Research Group, Division of Cancer Prevention
National Cancer Institute, National Institutes of Health
Bethesda, MD
02/1998-08/1999Senior Staff Fellow
Biometry Office, Epidemiology Demography & Biometry Program
National Institute on Aging
Bethesda, MD
06/1993-08/1993Actuarial Research InternCorporate Actuarial Department
The Principal Financial Group; Des Moines, Iowa.
09/1992-05/1993Visiting Assistant ProfessorDepartment of Mathematics and Computer ScienceDrake University, Des Moines, Iowa
09/1984-05/1990Teaching AssistantDepartment of MathematicsUniversity of Wisconsin-Madison
06/1996-08/1996Graduate Research FellowGeneral Motors Technical Center, Warren, Michigan
Department of Mathematics and Statistics
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Education
08/1996-02/1998IRTA Fellowship
Epidemiology, Demography, and Biometry Program
National Institute on Aging, Bethesda, Maryland
08/1994-08/1996 Post-doctoral Training Fellowship in the
Carolina Population Center and Biostatistics Department
University of North Carolina Chapel Hill
05/1993 PhD in Mathematics (Probability Theory)
with a minor in Computer Science
University of Wisconsin Madison
Thesis: Large deviations for additive functionals of a Markov exchangeable sequence.
Advisor: Peter E. Ney, Professor of Mathematics
05/1984 BA in Mathematics and Chemistry
Drake University
Des Moines, Iowa
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Awards and Honors
2011 Prostate Cancer Foundation Award for Abstract Entitled
"Family History of Various Cancers and the Risk of Incident Prostate Cancer in the PLCO
Trial"
2010 Performance Award
National Cancer Institute; Bethesda, Maryland
2002 Distinguished Service Award
National Cancer Institute; Bethesda, Maryland
1999 Performance Award
National Institute on Aging; Bethesda, Maryland
1998 Fellows Award for Research Excellence
National Institutes of Health
1994 Carolina Population Center Fellowship
University of North Carolina-Chapel Hill
1992 Department of Education Fellowship
Department of Mathematics
University of Wisconsin-Madison
1984 Member, Phi Beta Kappa
1984 Graduated summa cum laude
Drake University; Des Moines, Iowa
1982 & 1983 Summer Landau Fellow in Physical Chemistry
University of Minnesota-Minneaplolis
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Memberships
American Statistical Association
Eastern North American Region of the International Biometric Society
Institute of Mathematical Statistics
Interface Society of North America
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Referee Services
Bioinformatics
Biomed Central-Bioinformatics
Journal of the American Statistical Association
Nucleic Acids Research
Proteomics
Statistics in Medicine
Editorial Boards
Cancer Informatics
Research Interests
Statistical analysis of proteomics, SNP and microarray data
Statistical issues related to interim analysis
Stochastic processes issues in natural history models for cancer screening trials
Bibliography
Peer-Reviewed Journals
Andriole GL, Crawford ED, Grubb III RL, Buys SS, Chia C, Church TR, Fouad MN, Isaacs C,
Kvale PA, Reding DJ, Weissfeld JL, Yokochi LA, O Brien B, Ragard LR, Clapp JD, Rathmell
JM, Riley TL, Hsing AW, Izmirlian G, Pinsky PF, Kramer BS, Miller AB, Gohagan JK, Prorok
PC, and for the PLCO Project Team. Prostate cancer screening in the randomized Prostate,
Lung, Colorectal, and Ovarian Cancer Screening Trial: mortality results after 13 years of
follow-up . J Natl Cancer Inst 2012;104
Oken MM, Hocking WG, Kvale PA, Andriole GL, Buys SS, Church TR, Crawford ED, Fouad MN,
Isaacs C, Reding DJ, Weissfeld JL, Yokochi LA, O Brien B, Ragard LR, Rathmell JM, Riley
TL, Wright P, Caparaso N, Hu P, Izmirlian G, Pinsky PF, Prorok PC, Kramer BS, Miller AB,
Gohagan JK, Berg CD, for the PLCO Project Team. Screening by chest radiograph and lung
cancer mortality: The Prostate, Lung, Colorectal, and Ovarian (PLCO) Randomized Trial .
JAMA 2011;306(17):1865-1873.
The National Lung Cancer Screening Trial Research Team (Izmirlian G). Reduced lung-cancer
mortality with low-dose computed tomograpic screening. N Engl J Med 2011;365(5):395-409.
The National Lung Screening Trial Research Team (Izmirlian G). The National Lung
Screening Trial: overview and study design. Radiology 2011;258:243-253.
Crawford ED, Grubb RL, Black A, Andriole GL, Chen MH, Izmirlian G, Berg CD, D'Amico AV.
Comorbidity and mortality results from a randomized prostate cancer screening trial . J
Clin Oncol 2010;28.
Izmirlian G. Prostate-cancer screening. N Engl J Med 2009;361(2):204; author reply 205-
206.
Andriole GL, Grubb RL, Buys SS, Chia D, Church TR, Fouad MN, Gelmann EP, Kvale PA, Reding
DJ, Weissfeld JL, Yokochi LA, Crawford ED, O'Brien B, Clapp JD, Rathmell JM, Riley TL,
Hayes RB, Kramer BS, Izmirlian G, Miller AB, Pinsky PF, Prorok PC, Gohagan JK, Berg CD.
Mortality results from a randomized prostate-cancer screening trial. N Engl J Med
2009;360:1309-1319.
Grubb RL, Black A, Izmirlian G, Hickey TP, Pinsky PF, Mabie JE, Riley TL, Ragard LR,
Prorok PC, Berg CD, Crawford ED, Church TR, Andriole GL. Serum prostate-specific antigen
hemodilution among obese men undergoing screening in the Prostate, Lung, Colorectal and
Ovarian cancer screening trial. Cancer Epidemiology, Biomarkers and Prevention
2009;18(3):748-751.
Grubb RL, Pinsky PF, Greenlee RT, Izmirlian G, Miller AB, Hickey TP, Riley TL, Mabie JE,
Levin DL, Chia D, Kramer BS, Reding DJ, Church TR, Yokochi LA, Kvale PA, Weissfeld JL,
Urban DA, Buys SS, Gelmann EP, Ragard LR, Crawford ED, Prorok PC, Gohagan JK, Berg CD,
Andriole GL. Prostate cancer screening in the Prostate, Lung, Colorectal and Ovarian
cancer screening trial: update on findings from the initial four rounds of screening in a
randomized trial. BJU Int 2008;102(11):1524-1530.
Izmirlian G. Reply to 'Open Source Mathematical Software'. Notices of the American
Mathematical Society 2008;55(3):342.
Izmirlian G. Response to 'Receiver operating characteristics of the prostate-specific
antigen test in an unselected population'. J Med Screen 2006;13(4):214; author reply 215.
Steele VE, Arnold JT, Le H, Izmirlian G, Blackman MR. Comparative effects of DHEA and DHT
on gene expression in human LNCaP prostate cancer cells. Anticancer Research 2006;26:3205-
3216.
Xu J-L, Izmirlian G. Estimation of location parameters for a spherically symmetric
distribution. Journal of Multivariate Analysis 2006;97:514-525.
Andriole GL, Levin DL, Crawford ED, Gelmann EP, Pinsky PF, Chia D, Kramer BS, Reding D,
Church TR, Grubb RL, Izmirlian G, Ragard LR, Clapp JD, Prorok PC, Gohagan JK, for the PLCO
Project Team. Prostate cancer screening in the Prostate, Lung, Colorectal and Ovarian
(PLCO) Cancer Screening Trial: findings from the initial screening round of a randomized
trial. J Natl Cancer Inst 2005;97
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