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Project Research

Location:
Bethesda, MD
Posted:
September 30, 2012

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Research Groups

Major Programs

Resources for Investigators

Publications

Prevention Clinical Trials

Screening and Early Detection Clinical Trials

Supportive and Palliative Care Clinical Trials

Clinical Trials Management

Preventing & Detecting Specific Cancers

Lifestyle and Prevention

Meetings and Events

Scientific Scope

Research Groups and Offices

Research Networks Map

Staff Directory

Fellowships & Positions

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Research Groups

Foundations of Prevention:

Biometry

Publications

Software, Data Sets and Technical Reports

About the Research Group

Cancer Biomarkers

Chemopreventive Agent Development

Community Oncology and Prevention Trials

Early Detection

Nutritional Science

Organ Systems:

Breast and Gynecologic Cancer

Gastrointestinal and Other Cancers

Lung and Upper Aerodigestive Cancer

Prostate and Urologic Cancer

Major Programs

Resources for Investigators

Publications

Biometry Research Group

Curriculum Vitae forGrant Izmirlian

PhD

Mathematical Statistician

US Mail Address

Biometry Research Group, DCP

National Cancer Institute

Executive Plaza North, Room 31316130 Executive Blvd, MSC 7354

Bethesda, MD 20892-7354 Shipping Address

Biometry Research Group, DCP

National Cancer Institute

6130 Executive Blvd, Room 3131

Rockville, MD 20852

Phone: 301-***-**** Fax: 301-***-****

E-mail: *********@***.***

Professional Experience

Education

Awards and Honors

Memberships

Referee Services

Editorial Board

Research Interests

Bibliography

Peer-Reviewed Journals

Published Abstracts

Professional Experience

08/1999-presentMathematical Statistician

Biometry Research Group, Division of Cancer Prevention

National Cancer Institute, National Institutes of Health

Bethesda, MD

02/1998-08/1999Senior Staff Fellow

Biometry Office, Epidemiology Demography & Biometry Program

National Institute on Aging

Bethesda, MD

06/1993-08/1993Actuarial Research InternCorporate Actuarial Department

The Principal Financial Group; Des Moines, Iowa.

09/1992-05/1993Visiting Assistant ProfessorDepartment of Mathematics and Computer ScienceDrake University, Des Moines, Iowa

09/1984-05/1990Teaching AssistantDepartment of MathematicsUniversity of Wisconsin-Madison

06/1996-08/1996Graduate Research FellowGeneral Motors Technical Center, Warren, Michigan

Department of Mathematics and Statistics

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Education

08/1996-02/1998IRTA Fellowship

Epidemiology, Demography, and Biometry Program

National Institute on Aging, Bethesda, Maryland

08/1994-08/1996 Post-doctoral Training Fellowship in the

Carolina Population Center and Biostatistics Department

University of North Carolina Chapel Hill

05/1993 PhD in Mathematics (Probability Theory)

with a minor in Computer Science

University of Wisconsin Madison

Thesis: Large deviations for additive functionals of a Markov exchangeable sequence.

Advisor: Peter E. Ney, Professor of Mathematics

05/1984 BA in Mathematics and Chemistry

Drake University

Des Moines, Iowa

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Awards and Honors

2011 Prostate Cancer Foundation Award for Abstract Entitled

"Family History of Various Cancers and the Risk of Incident Prostate Cancer in the PLCO

Trial"

2010 Performance Award

National Cancer Institute; Bethesda, Maryland

2002 Distinguished Service Award

National Cancer Institute; Bethesda, Maryland

1999 Performance Award

National Institute on Aging; Bethesda, Maryland

1998 Fellows Award for Research Excellence

National Institutes of Health

1994 Carolina Population Center Fellowship

University of North Carolina-Chapel Hill

1992 Department of Education Fellowship

Department of Mathematics

University of Wisconsin-Madison

1984 Member, Phi Beta Kappa

1984 Graduated summa cum laude

Drake University; Des Moines, Iowa

1982 & 1983 Summer Landau Fellow in Physical Chemistry

University of Minnesota-Minneaplolis

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Memberships

American Statistical Association

Eastern North American Region of the International Biometric Society

Institute of Mathematical Statistics

Interface Society of North America

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Referee Services

Bioinformatics

Biomed Central-Bioinformatics

Journal of the American Statistical Association

Nucleic Acids Research

Proteomics

Statistics in Medicine

Editorial Boards

Cancer Informatics

Research Interests

Statistical analysis of proteomics, SNP and microarray data

Statistical issues related to interim analysis

Stochastic processes issues in natural history models for cancer screening trials

Bibliography

Peer-Reviewed Journals

Andriole GL, Crawford ED, Grubb III RL, Buys SS, Chia C, Church TR, Fouad MN, Isaacs C,

Kvale PA, Reding DJ, Weissfeld JL, Yokochi LA, O Brien B, Ragard LR, Clapp JD, Rathmell

JM, Riley TL, Hsing AW, Izmirlian G, Pinsky PF, Kramer BS, Miller AB, Gohagan JK, Prorok

PC, and for the PLCO Project Team. Prostate cancer screening in the randomized Prostate,

Lung, Colorectal, and Ovarian Cancer Screening Trial: mortality results after 13 years of

follow-up . J Natl Cancer Inst 2012;104

Oken MM, Hocking WG, Kvale PA, Andriole GL, Buys SS, Church TR, Crawford ED, Fouad MN,

Isaacs C, Reding DJ, Weissfeld JL, Yokochi LA, O Brien B, Ragard LR, Rathmell JM, Riley

TL, Wright P, Caparaso N, Hu P, Izmirlian G, Pinsky PF, Prorok PC, Kramer BS, Miller AB,

Gohagan JK, Berg CD, for the PLCO Project Team. Screening by chest radiograph and lung

cancer mortality: The Prostate, Lung, Colorectal, and Ovarian (PLCO) Randomized Trial .

JAMA 2011;306(17):1865-1873.

The National Lung Cancer Screening Trial Research Team (Izmirlian G). Reduced lung-cancer

mortality with low-dose computed tomograpic screening. N Engl J Med 2011;365(5):395-409.

The National Lung Screening Trial Research Team (Izmirlian G). The National Lung

Screening Trial: overview and study design. Radiology 2011;258:243-253.

Crawford ED, Grubb RL, Black A, Andriole GL, Chen MH, Izmirlian G, Berg CD, D'Amico AV.

Comorbidity and mortality results from a randomized prostate cancer screening trial . J

Clin Oncol 2010;28.

Izmirlian G. Prostate-cancer screening. N Engl J Med 2009;361(2):204; author reply 205-

206.

Andriole GL, Grubb RL, Buys SS, Chia D, Church TR, Fouad MN, Gelmann EP, Kvale PA, Reding

DJ, Weissfeld JL, Yokochi LA, Crawford ED, O'Brien B, Clapp JD, Rathmell JM, Riley TL,

Hayes RB, Kramer BS, Izmirlian G, Miller AB, Pinsky PF, Prorok PC, Gohagan JK, Berg CD.

Mortality results from a randomized prostate-cancer screening trial. N Engl J Med

2009;360:1309-1319.

Grubb RL, Black A, Izmirlian G, Hickey TP, Pinsky PF, Mabie JE, Riley TL, Ragard LR,

Prorok PC, Berg CD, Crawford ED, Church TR, Andriole GL. Serum prostate-specific antigen

hemodilution among obese men undergoing screening in the Prostate, Lung, Colorectal and

Ovarian cancer screening trial. Cancer Epidemiology, Biomarkers and Prevention

2009;18(3):748-751.

Grubb RL, Pinsky PF, Greenlee RT, Izmirlian G, Miller AB, Hickey TP, Riley TL, Mabie JE,

Levin DL, Chia D, Kramer BS, Reding DJ, Church TR, Yokochi LA, Kvale PA, Weissfeld JL,

Urban DA, Buys SS, Gelmann EP, Ragard LR, Crawford ED, Prorok PC, Gohagan JK, Berg CD,

Andriole GL. Prostate cancer screening in the Prostate, Lung, Colorectal and Ovarian

cancer screening trial: update on findings from the initial four rounds of screening in a

randomized trial. BJU Int 2008;102(11):1524-1530.

Izmirlian G. Reply to 'Open Source Mathematical Software'. Notices of the American

Mathematical Society 2008;55(3):342.

Izmirlian G. Response to 'Receiver operating characteristics of the prostate-specific

antigen test in an unselected population'. J Med Screen 2006;13(4):214; author reply 215.

Steele VE, Arnold JT, Le H, Izmirlian G, Blackman MR. Comparative effects of DHEA and DHT

on gene expression in human LNCaP prostate cancer cells. Anticancer Research 2006;26:3205-

3216.

Xu J-L, Izmirlian G. Estimation of location parameters for a spherically symmetric

distribution. Journal of Multivariate Analysis 2006;97:514-525.

Andriole GL, Levin DL, Crawford ED, Gelmann EP, Pinsky PF, Chia D, Kramer BS, Reding D,

Church TR, Grubb RL, Izmirlian G, Ragard LR, Clapp JD, Prorok PC, Gohagan JK, for the PLCO

Project Team. Prostate cancer screening in the Prostate, Lung, Colorectal and Ovarian

(PLCO) Cancer Screening Trial: findings from the initial screening round of a randomized

trial. J Natl Cancer Inst 2005;97

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