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High School Project

Location:
Chapel Hill, NC
Posted:
September 28, 2012

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Resume:

CURRICULUM VITAE

TIM WILTSHIRE

PH.D

Personal Information

Office Address: 1015 Genetic Medicine

*** ***** **** ****, ** 7361

Division of Pharmacotherapy and Experimental Therapeutics,

UNC Eshelman School of Pharmacy

University of North Carolina at Chapel Hill

Chapel Hill, NC 27599

Office: 919-***-****

Lab: 919-***-****

Fax: 919-***-****

Email: ****@***.***

Home Address: 1000 Wood-Sage Dr.

Chapel Hill, NC 27516

919-***-****

Academic Appointments

Associate Professor 2007 present

Division of Pharmacotherapy and Experimental Therapeutics

UNC Eshelman School of Pharmacy

Faculty member 2007 present

Associate Director, Institute for Pharmacogenomics and Individualized Therapy

Adjunct Faculty 2010 present

Department of Genetics

UNC School of Medicine

Faculty member 2010 present

Lineberger Comprehensive Cancer Center

Professional Education and Training:

Bachelors of Science, major in Organic Chemistry. B.Sc. 1972 - 1975

The University of Canterbury (Christchurch, New Zealand)

Diploma in Teaching, Dip.Teach. 1975

High School Teacher training

Christchurch Teachers College (Christchurch, New Zealand).

Post-Graduate Diploma in Science, major in Biotechnology. Dip.Sci.(Hons) 1990 - 1991

The University of Otago (Dunedin, New Zealand).

Thesis Project: Comparison of oil levels in accessions of Myoporum laetum and development

of a

tissue culture protocol for M. laetum.

Advisor: Dr. Paula Jameson

Doctor of Philosophy in Biochemistry, Cellular and Molecular Biology. Ph.D. 1991 - 1996

The University of Tennessee, Knoxville, Tennessee.

Dissertation: Mammalian Meiosis: Events of meiotic prophase I in spermatogeneisis

Advisor: Dr. Mary Ann Handel

Postdoctoral Research

Post-Doctoral Fellow, Department of Physiology 1996 - 1998

The Johns Hopkins University School of Medicine

Advisor: Dr. Roger Reeves

Post-Doctoral Fellow, Center for Neurobiology and Behavior 1998 - 1999

University of Pennsylvania School of Medicine

Advisor: Dr. Maja Bucan

Other Employment:

High School Teacher (New Zealand trained teacher certification) 1980 - 1991

Teaching general science classes and chemistry and biology to advanced levels

Waikohu College Te Karaka 1980 - 1981

Motueka High School Motueka (Head of Biology and Outdoor Education) 1982 - 1991

Institute Research Fellow 2000

Genomics Institute of the Novartis Research Foundation, a division of Novartis

PharmaceuticalsStaff Scientist2001 - 2003

Genomics Institute of the Novartis Research FoundationGenetics Group Leader2003 - 2006

Genomics Institute of the Novartis Research FoundationSenior Research Investigator Genetics 2006 - 2007

Genomics Institute of the Novartis Research Foundation

San Diego, CA

Professional Activities and Services:

Course Instructor, Cloning and Analysis of Large DNA - Cold Spring Harbor Laboratory, NY

1996

Course Instructor, Positional Cloning Course - Cold Spring Harbor Laboratory, NY 1997National Cancer Institute - (Think Tank participant) September 12-14, 2004

Cancer Susceptibility and Resistance

National Cancer Institute - (Think Tank participant) December 6-7, 2005

Predictive Models of Cancer Susceptibility: Integrated Strategies

Host Susceptibility meeting, participant/consultant December 2006

National Toxicology Program (NIEHS)

NCI-Integrated Systems Genetics Meeting participant March 11-13 2008

Newport Beach, CA.

National Institutes of Health

Reviewer for NIEHS special emphasis panel 2007

Comparative Biology Elucidation of Environmental Pathways and Susceptibility

Reviewer for NIH GCAT Study sections, 2007, 2008

Genomics, Computational Biology and Technology

Reviewer for NIH ARRA Challenge Grant Program (RFA-OD-09-003) 2009

National Institutes of Health (NIH).

Journal Reviews

Reviewer for scientific journals: Genomics, Mammalian Genome, Genome Research, Nature

Genetics, Genetics, Trends in Genetics, Physiological Genomics, BMC Genomics, and PLoS

Biology, PLoS ONE.

Inventions

US Patent number 7,595,148

This invention provides novel methods and compositions for modulating T cell

differentiation and T

cell responses.

UNC-Chapel Hill

Member, UNC IACUC committee 2008 - present

Sub-committee responsibilities mouse genetics

Faculty Search Committee Genetics Dept.

UNC School of Medicine

UNC Eshelman School of Pharmacy

Member, Conflict of Interest committee (COIC)

Interviewer graduate program applicants

Institute of Pharmacogenomics and individualized Therapy

Associate Director for Pre-Clinical Studies

Professional Memberships

American Association for Advancement of Science (AAAS) 1993 - present

American Society of Human Genetics (ASHG) 2005 - present

International Mouse Genome Society 1997 - present

Elected member of Nominations committee 2010

Awards

Post-Primary Teachers Association New Zealand Teacher of the year award. 1986

Nominated by students

University of Tennessee - Science Alliance Graduate Student Award of Excellence, 1994 and

1995

University of Tennessee Chancellors Award 1996

.

7. Rakhra-Burris TK, Auman JT, Deverka P, Dressler LG, Evans JP, Goldberg RM, Havener

TM, Hoskins JM, Jonas DE, Long KM, Motsinger-Reif AA, Irvin WJ, Richards KL,

Roederer MW, Valgus JM, Riper M, Vernon JA, Zamboni WC, Wagner MJ, Walko CM,

Education Network, 8 International Meeting, November 2010.

Teaching

High School Subjects taught to lower grade levels, Biology, Chemistry, Physics, Earth

Sciences, and Mathematics. Subjects taught to advanced grade levels, Biology, Chemistry.

Outdoor Education, also taught to senior students.

Biology 101 labs University of Tennessee undergraduate program.

Biotechnology Lab class University of Tennessee graduate program.

Graduate Program (Ph.D. in Pharmaceutical Sciences)

Course Coordinator 2009 - present

DPET 838 Methods in Pharmacogenetics

Lecturer 2008 - present

DPET 832 Pharmacogenomics

Advisor 2008 -present

DPET 991 Research in DPET

Dissertation Committees

Division of Pharmacotherapy and Experimental Therapeutics

Cristina Santos (Major Advisor)

Amber Frick (Major Advisor)

Shawn Watson (Committee Chair)

Venita Gresham completed defense April, 2010

Graduate Program Curriculum of Genetics and Molecular Biology, University of North

Carolina

Samantha Segall (Major Advisor) completed defense September 2010

Yuying Xie (Threadgill major advisor) completed defense July 2010

Graduate Program Curriculum in Toxicology, Environmental Genetics Group, NIEHS

Monica High - completed defense March 2010 (Kleeberger - major advisor)

Jennifer Nicholls (Kleeberger - major advisor)

Graduate Program Department of Cell and Molecular Physiology

Shiliang Wang (Faber major advisor)

Department of Biostatistics, School of Public Health

Yi Gong (Zou - major advisor)

Post-Doctoral Advisor

Mat Pletcher - Senior Principal Scientist, Investigative Toxicology Pfizer Global

Research and

Development. Groton CT.

David DelanoProduct Manager, Epigenetics. Illumina Corp, San Diego, CA.

Steven Su Scientist, Merrimack Pharmaceuticals, Boston MA

Current post-doctoral fellows

Natasha Butz

Oscar Suzuki

Current Research Support

1R01MH077251-01A1 (Wiltshire) 7/01/2007 - 4/31/2012

NIMH $250,000

Organismal, Cellular and Genetic Networks in Anxiety and Depression

The major goals of this project are to collect and analyze anxiety and depression-related

genetic,

biochemical and clinical phenotype data related in inbred mouse strains.

1 R01 DOA022392-01(Tarantino) Co-PI -10% 7/01/2007 7/01/2011

NIDA $250,000

Fine Mapping Genes for Cocaine Locomotor Response in ENU Mutagenized Mice

The major goals of this project are to map, identify and characterize the gene underlying

a

cocaine locomotor response in an ENU mutant mouse.

5R01DA023690-02 (Tarantino, Wiltshire, coPIs) 8/01/2010 7/31/2011

NIDA $390,000

Organismal and Genetic Networks in Drug Reward and Reinforcement.

The major goals of this project are to collect and analyze drug reward and reinforcement-

related

genetic, biochemical and clinical phenotype data related in inbred mouse strains.

Completed Research Support

Novartis Grant SFP-1407. Internal special project funding support within Novartis to

develop

SNP mapping technologies.



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