NAME POSITION
Resume:
Carlos Antonio Paladini
CV
CURRICULUM VITAE
NAME POSITION TITLE / ADDRESS
Assistant Professor
Carlos Antonio Paladini
Department of Biology
University of Texas at San Antonio
San Antonio, TX 78249
aboqxq@r.postjobfree.com
EDUCATION/TRAINING
INSTITUTION AND LOCATION DEGREE YEAR FIELD
Rutgers University, Newark NJ, USA B.A. 1992 Zoology and Physiology
Rutgers University, Newark NJ, USA Ph. D. 1999 Neuroscience
Vollum Institute, Portland OR, USA Post-doc
Research and Professional Experience
Assistant Professor. Department of Biology, UTSA Neurosciences Institute
. 3/05 present:
Research Assistant Professor. Department of Behavioral Neuroscience, OHSU School1/033/05:
of Medicine. Cellular Mechanisms in Cocaine Self-Administration.
2/99 12/02: Postdoctoral fellow. Advisor: Dr. John T. Williams. Function and
pharmacology of the
IPSP induced by glutamate acting via metabotropic glutamate receptors.
1/95 10/98: Graduate student. Advisor: Dr. James. M. Tepper. Basal ganglia function and
anatomy focusing on afferent control of nigrostriatal dopamine neurons of the substantia
nigra pars
compacta.
Publications
1) Ko, D., Wilson, C., and Paladini, C. A.; Identification of Bursts and Pauses in Spike
Train Data.
In preparation.
2) Kuznetsova, A. Y., Paladini, C. A., Canavier, C. C., and Kuznetsov, A. S.; Firing
Frequency
Regulation in the Coupled Oscillator Model of the Midbrain Dopaminergic Neuron. Submitted
to J.
Neurophys.
2) Lobb C.J., Wilson C.J., and Paladini C.A.; (2008) Silencing Dopaminergic Neurons:
Results from
in vitro studies. Soc. Neurosci. Abstr. 179.7
3) Paladini C.A. and Lobb C.J.; (2008) Bursting in Midbrain Dopaminergic Neurons: Results
from
Cell-Specific NMDAR Knockouts. Soc. Neurosci. Abstr. 179.6
4) Teagarden M.A., Deister C.A., Wilson C.J., and Paladini C.A.; (2008) NMDA receptor
amplification of an intrinsic oscillator enables high-frequency spiking in substantia
nigra dopamine
neurons. Soc. Neurosci. Abstr. 179.5
5) Teagarden M.A., Deister C.A., Wilson C.J., and Paladini C.A.; High frequency
oscillations
induced by NMDAR activation allow burst firing in substantia nigra pars compacta dopamine
neurons. SFN 2007 abstract.
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Carlos Antonio Paladini
CV
6) Goertz R.B. and Paladini C.A.; Effects of prolonged PI-coupled receptor activation on
the
glutamate-induced firing patterns of midbrain dopamine neurons. SFN 2007 abstract.
7) Lobb C.J., Wilson C.J., and Paladini C.A.; GABA-mediated inhibition of single-spiking
and burst
A
firing in midbrain dopamine neurons. SFN 2007 abstract.
8) Deister C, Wilson C. J., and Paladini C. A.; (2006) NMDA receptor control of burst
firing in
midbrain dopamine neurons. Soc. Neurosci. Abstr. 637:23
Carlos Antonio Paladini
CV
4) Winter Conference on Brain Resear ch (WCBR) Travel Fellowship, 2002
5) Tartar Trust Fellowship (OHSU), 2001
6) National Research Service Award (NRSA) NIDA/NIAAA postdoctoral institutional
fellowship, 1999 - 20
7) National Research Service Award (NR SA) NIMH predoctoral fellowship, 1998 - 1999
8) Elizabeth H. Solomon Training Award (Center for Molecular and Behavioral
Neuroscience),
Rutgers University; 1996
Committees and Services
1) 2008: Temporary Member; Center for Scientific Review (NIH/CSR) Neurobiology of
Motivated
Behavior (NMB).
2) 2007 - 2008: UTSA Neurobiology Seminar Series organizer. UTSA Biology Department
program in Neurobiology.
3) Ad Hoc Reviewer: Journal of Neuroscience, Journal of Physiology, Neuron, National
Science
Foundation, Neuropsychopharmacology, Neuroscience Letters, Brain Research.
4) 2006 2008: Member Special Emphasis Panel/Scientific Review Group 2006/2005,
2007/2006
ZRG1 F02B-B
5) 2007 - Winter Conference on Brain Research (WCBR) session organizer: Cellular
Mechanisms
of Dopamine Neuron Bursting.
6) 2006 - 2007: UTSA Doctoral Studies Committee; Budget Committee
7) 2005: UTSA Community Relations Co mmittee; Doctoral Studies Committee
8) 2004 2005: Community Homeowners Association Board of Directors Elected Member.
9) 2001 2003: NINDS Specialized Neuroscience Research Program (SNRP) collaborator in
technology transfer with Universidad Cent ral del Caribe (UCC; Puerto Rico).
10) 2002: Dopamine 2002 quadrennial meeting: Po ster Presentation Judging Committee.
11) 2002: Winter Conference on Brain Research (WCBR) session organizer: Synaptic and Non-
Synaptic Regulation of Dopamine Neurons
12) 1999 2000: Co-coordinator for OHSU NIDA/NIAAA Journal Club
13) 1995 - 1998: CMBN Travel Award Committee
14) 1996: Newark Graduate and Postdoctoral Minisymposium Judging Committee
15) 1995: Newark Graduate and Postdoctoral Minisymposium Organizing Committee
Invited Talks
1) Psychostimulant Effects on Dopamine Neuron Firing. Kunming Institute of Zoology,
Chinese
Academy of Sciences. Kunming, China. 2008
2) Bursts and Pauses in Dopamine Neuron Firing. Rutgers University Center for Molecular
and
Behavioral Neuroscience Special Seminar. Newark, NJ. 2007.
3) Dopamine Neuron Firing Pattern and Amphetamine. University of Texas at Austin
Pharmacology and Toxicology Department. Austin, TX. 2006
4) Dopamine Neuron Firing Pattern and Behavior. University of Texas Health Science Center
at
San Antonio (UTHSCSA). San Antonio, TX. 2006.
5) Interactions Among Phosphoinositide Hydrolysi s-Coupled Receptors Affect Dopamine
Neuron
Activity. UTSA Cell & Molecular Biology Se minar Series. San Antonio, TX. 2005.
6) Control of Dopamine Neuron Firing Pattern by Noradrenergic Receptors. Winter
Conference on
Brain Research (WCBR). 2005.
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Carlos Antonio Paladini
CV
7) Noradrenergic Modulation of Midbrain Dopamine Neurons. Winter C onference on Brain
Research
(WCBR). 2003.
8) Cocaine self-administration selectively dec reases noradrenergic regulation of mGluR-
mediated
inhibition in dopamine neurons. Winter Confer ence on Brain Research (WCBR). 2002.
9) GABAergic Control of Dopaminergic Neuron Firing Pattern. Bridges Seminar Series:
Division of
Biology, Chemistry and Health Technologies. Essex County College. Newark, NJ. 1997.
Teaching Experience
Fall 2007present: Instructor: N euroanatomy; UTSA (g raduate students)
Fall 2006present: Instructor
: N eurojournal; UTSA (graduate students)
Fall 2005 - Lecturer: Drugs and Society; UTSA (250 undergraduate students)
Spring 2003 - Lecturer: Neurophysiology Lecture Series; OHSU (neurology residents)
Spring 2000 - Lecturer: Neurophysiology Lecture Series; OHSU (neurology residents)
Spring 1998 - Discussion section lecturer: Empirical Methods in Psychology; Ru tgers
(undergraduate stude
Spring 1996 - Teaching assistant: Cellular N europhysiology; Rutgers (graduate students)
Fall 1995 - Teaching assistant: Neuroanatom y; CMBN, Rutgers (graduate students)
Fall 1994 - Discussion section leader: General Bi ology 101; Rutgers (undergraduate
students)
Fall 1993 - Teaching assistant: Foundations in Neuroscience; CMBN, Rutgers (graduate
students)
Student Mentorship
Masters students Andrew Adorboe, Kelly Thomas - masters exam committee.
Ph.D. Candidates Collin Lobb, Richard Goertz, Yonas Keleta.
Dissertation committees Anne Baumgartner, Chris Deister.
Professional Societies
Society for Neuroscience (SFN); 1994 present
International Basal Ganglia Society (IBAGS); 2004 present
National Hispanic Science Network (NHSN); 2005 present
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Carlos Antonio Paladini
CV
Research Support
Ongoing Research Support
U54 NS060658- Paladini (PI) 2008 2013
NINDS
Control of dopamine neuron firing by phosphoinosotide-coupled receptors
This study is an investigation of the synaptic mechanisms induced by PI-coupled receptors
that
influence the firing pattern of dopaminergic neurons.
Role: PI
R01 MH079276- Paladini (PI) 2007 2012
NIMH
Cellular Mechanisms Dopamine Neuron Bursting.
This study is an investigation of the cellular mechanisms that enable dopaminergic
neurons to fire at
high frequencies and the mechanisms involved in pauses in firing.
Role: PI
K01 DA016262- Paladini (PI) 2003 2008
NIDA
Cellular Mechanisms in Cocaine Self-Administration.
This study is an investigation of the changes in synaptic inputs to midbrain dopamine
neurons
induced by drug seeking.
Role: PI
Completed Research Support
YI2002 Young Investigator Award- Paladini (PI) 2002 2004
NARSAD
mGluR Heterologous Desensitization: A Cellula r Mechanism for Dopamine Cell Firing
Control.
This study investigates the effects of metabotropic glutamate receptors on dopamine cell
firing under
differing conditions of receptor desensitization.
Role: PI
NRSA T32 Institutional Fellowship 1999 2001
NIDA/NIAAA
Role: Fellow
1 F31 MH11947-01A1- Paladini (PI) 1998 - 1999
NIMH
Role: PI
aboqxq@r.postjobfree.com 6
Carlos Antonio Paladini
CV
References
Oxford J. Paul Bolam, Ph.D. Oxford University, MRC Anatomical Neuropharmacology Unit,
England, UK. Tel: 186-***-****; Fax: 186-***-****;
aboqxq@r.postjobfree.com
Antonello Bonci, M.D. UCSF, Ernest Gallo Clinic and Research Center, San Francisco CA.
Tel:
510-***-**** Fax: 510-***-****; aboqxq@r.postjobfree.com
James M. Tepper, Ph.D. Rutgers University, C enter for Molecular and Behavioral
Neuroscience,
Newark NJ. Tel: 973-***-**** ext.3151; Fax: 973-***-****;
aboqxq@r.postjobfree.com
John T. Williams, Ph.D. Oregon Health & Science Un iversity, Vollum Institute, Portland
OR. Tel:
503-***-****; Fax: 503-***-****; aboqxq@r.postjobfree.com
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