Quality Control Development

Dr. HITESHKUMAR MANUBAHI PAREKH

D-**, Vasudha Society, Nr Payal Cinema, VASAD-388 306, TA/DI- Anand, Gujarat, India

Contact: +91-989**-***** E-mail: *******@*****.***

+27-839*-***** (SA)

Synthesis-API ~ R&D ~ Research Scientist (Pharmaceuticals)

Research & Development Quality Control/API/AMD Chemical Analysis Instruments Calibration

Lab Commissioning Lab Operations/Procurement Planning/Scheduling Research Data Compilation

Problem Resolution Compound Purification Synthetic Root Development Literature Survey

Process Development Documentation/MIS Training & Development Team Leadership

6+ years’ rich experience in conceptualizing, planning and guiding R&D projects to evolve technological

solutions and build strong base of patented products. Proactive and industrious, with a comprehensive exposure of

both collaborative and independent research. High-performing professional with a reputation of unwavering accuracy

& consistently delivering results towards designing, coordinating and analyzing various compounds and their

outcomes. Proficient in preparation of research reports and manuscripts for publications. Dexterity in using

sophisticated analytical instruments viz. IR, NMR, HPLC, GC and LCMS & well versed with various techniques as

Chromatographic, Spectral analysis & Microwave Synthesis. Well acquainted with chem draw and chem sketch. Thrive

in a deadline intensive environment, multi-task, perform under pressure and meet deadlines. Suave and pragmatic

with excellent interpersonal and communication skills; competent to work in highly diverse environments with people

from varied backgrounds; popular team worker with leadership traits. Excellent man-management, time management,

and leadership skills.

INSTRUMENTS HANDLED

NMR Bruker Avance III PH-Meter Karl Fischer HPLC

Perkin Elmer ATR spectrometer Autoclaves Gas Chromatography TG Analyzer

Scholastic Credentials

June-2011 Post Doctorate Research Scholar at the University of KwaZulu-Natal, Westville Campus, Durban,

South Africa

May-2006 Ph. D. in Chemistry from Sardar Patel University, Vallabh Vidyanagar, Gujarat, India

April-2002 M. Sc. In Chemistry with Second Division from Sardar Patel University, Vallabh Vidyanagar, Gujarat,

India

April-2000 B. Sc. In Chemistry with Second Division from M. B. Patel Science College, Sardar Patel University,

Vallabh Vidyanagar, Gujarat, India

Career Highlights

Since June 2011 with The University of kwaZulu-Natal as Post Doctorate Research Scholar, School

of Chemistry

Working with the catalysis research group (catalysis.ukzn.ac.za) Prof. Holger B. Friedrich & Dr. Glenn Maguire

in the area of homogeneous catalysis (Cavitand Chemistry).

Work includes multistep organic synthesis to prepare Cavitand-capped Porphyrin analogue of Cytochrome

P450 Enzyme for selective catalysis. Project is sponsored by “Centre of Excellence in Catalysis -DST/NRF-

South Africa”.

Sep ’08 to June ’11 with Dishman Pharmaceuticals and Chemicals Ltd., as Research Scientist (API

& CRO division), Ahmedabad

Organization mainly popular for Anti-Bacterial, Anesthetic, Anti-hyperlipidmic, Antibiotic, Oncology, Anti-

tuberculosis, disinfectant & CRAMS products.

Worked on molecules like, Besifloxacine, Pantoprazole sodium sesquihydrade, Paliperidone, Rapthyl acid

PEA salt, Technologies transferred from laboratory to Kilo -lab, pilot plant and finally in plant using complete

efficacy with online monitoring, and DMF filling

Design multi step synthesis, Purification and Characterization by using modern Chromatographic and

Spectroscopic Techniques

Practical experience of scaling up products from 100mg to 1 Kg. Level

Oct ’06 to Sep ’08 with Zydus Cadila Healthcare Ltd., as Executive Research Scientist (API

division), Ankleshwar

Developed molecules like Atorvastatin Ca, Cilensetron, Pantoprazole Na, Duloxetine HCl, Candesartan

Reduced cost of Atorvastatin & Pantoprazole and technology transferred successfully

Drug master filling

Mar ’06 to Oct ’06 with Cheminova India Ltd., as Senior Officer, Panoli, Ankleshwar

Literature survey for new product & existing product for process development by using Sci -Finder and CA for

Flufenacet (Herbicide) & Monocroto phos

Publications

Bisthiourea: thermal and structural investigation. Journal of Thermal Analysis and Colorimetry, 2013,

111, 597–603.

Coordination polymeric assemblies of some d-block elements with Schiff bases and its characterization.

Journal of Macromolecular Science Part A: Pure and Applied Chemistry, 2007, 44(1), 1-6.

Polymeric coordination compounds derived from transition metal (II) with tetradentate Schiff bases:

synthetic, spectroscopic, magnetic and thermal approach. Journal of Macromolecular Science Part A:

Pure and Applied Chemistry, 2007, 44(6), 599-603.

Synthesis, physicochemical characteristic and biocidal activity of some transition metal mixed -ligand

complexes with bidentate (NO & NN) Schiff bases. Pharmaceutical Chemistry Journal, 2007, 41(2),

78-81.

Preparation of Schiff base complexes of Mn(II), Co(II), Ni(II), Cu(II), Zn(II) and Cd(II) and their

spectroscopic, magnetic, thermal and antifungal studies. Russian Journal of Coordination Chemistry,

2006, 32(6), 431-436.

Transition metal(II) ions with dinegative tetradentate Schiff base. Synthesis, thermal, spectroscopic and

coordination aspects. Journal of Thermal Analysis and Calorimetry, 2006, 86(3), 803-807.

In-vitro fungitoxic activity of some Schiff bases and their oxovanadium(IV) complexes. Toxicological and

Environmental Chemistry, 2006, 88(4), 579-586.

Mode of antifungal activity and Synthesis of mixed-ligand complexes. Pharmaceutical Chemistry Journal,

2006, 40(12), 655-659.

Synthesis and antifungal activity of oxovanadium(IV) complexes with Schi ff bases. Pharmaceutical

Chemistry Journal, 2006, 40(9), 494-497.

Synthesis, structural characterization and antifungal activity of the Schiff bases and their transition metal

mixed-ligand complexes. Russian Journal of Inorganic Chemistry, 2006, 51(1), 67-72.

Bactericidal activity of different oxovanadium(IV) complexes with Schiff bases and application of chelation

theory. Journal Enzyme Inhibition and Medicinial Chemistry, 2006, 21(2), 203-209.

Synthesis and physicochemical study of 3d metal coordination polymers with dinegative tetradentate (NSNS)

Schiff base. Polish Journal of Chemistry, 2006, 80, 989-992.

Characterization and antifungal study of genuine oxovanadium(IV) mixed -ligand complexes with Schiff bases.

Polish Journal of Chemistry, 2005, 79, 1843-1851.

Synthesis, structural elucidation, electro-chemical behaviour and fungitoxic activity of transition metal(II)

mixed-ligand complexes with some Schiff bases. Toxicological and Environmental Chemistry, 2005,

87(4), 449-461.

Preparation, characterization and toxic activity of oxovanadium(IV) mixed-ligand complexes. Toxicological

and Environmental Chemistry, 2005, 87(1-4), 313-320.

Synthesis, characterization and biological evaluation of manganese(II), cobalt(II), nickel(II), copper(II) and

cadmium(II) complexes with monobasic (NO) and neutral (NN) Schiff bases. Transition Metal Chemistry,

2005, 30(1), 13-17.

Conference and Seminar Participated

Paper Presentations: 10

International/National Professional Meetings: 14

IT Skill

Windows, MS Office based applications, CorelDraw, ChemDraw Ultra 10.0

CS ChemOffice, ISIS Draw, ChemSW, IR solution

Strength

Strong communication, multidisciplinary work skill, Knowledge of WHO/ICH/ISO/

/Pharmacopeia/MSDS.

Interpersonal learning and organizing skills matched with the ability to manage stress, time and

people effectively.

Always hungry of challenges and knowledge.

Linguistic abilities: English, Gujarati, Hindi [Passed IELTS Exam with 6.0 bands]

References

Prof. Holger B. Friedrich Dr. M. N. Patel Dr. Glenn Maguire

School of Chemistry Professor in Chemistry School of Chemistry

Westville Campus Department of Chemistry University of KwaZulu-Natal,

University of KwaZulu-Natal Sardar Patel University Durban 4041 South Africa

Durban 4041 South Africa Vallabh Vidyanagar, Gujarat Email: ********@****.**.**

Email: ********@****.**.** Email:******@*****.*** Tel: +27-31-260****

Tel: +27-31-260**** Cell: +91-942*******

Fax: +27-31-260****

Personal details

th

Date of Birth: 11 March, 1979

Height: 5 9

Weight: 70 Kg

Marital status: Married

Wife: Jagruti Parekh, B. A.-Philosophy

Father: Principal

Mother: Teacher

Dr. Hitesh M. Parekh

Contact this candidate