Medical Management
Resume:
CURRICULUM VITAE
PART I: General Information
Date Prepared: 9/30/2010
Name: Philip Richard Orrin Payne
Office Address: The Ohio State University
Department of Biomedical Informatics
**** ****** Hall
th
333 W. 10 Avenue
Columbus, OH 43210
Tel.: 614-***-****; Fax.: 614-***-****
Email: ******.*****@*****.***
Web: http://bmi.osu.edu/~payne
Home Address: 7098 Violet Veil Court
Dublin, OH 43016
Place of Birth: San Diego, CA (Citizen of United States)
Education:
1995-1999: B.A. University of California - San Diego, La Jolla, CA (Political Science)
1999-2000: M.A. Columbia University, New York, NY (Medical Informatics)
2003-2006: M.Phil. Columbia University, New York, NY (Biomedical Informatics)
Ph.D. Columbia University, New York, NY (Biomedical Informatics)*
* With Distinction
Academic Appointments:
2006-2010: Assistant ProfessorDepartment of Biomedical Informatics, The Ohio State University
2008-present: Director, Biomedical Informatics Program
The Ohio State University,
Center for Clinical and Translational Science
2008-2010: Senior Scientific Advisor
The Ohio State University, Center for IT Innovation in Healthcare
2009-present: Director of Data Management Services, Biomedical Informatics Shared
Resource
The Ohio State University, Comprehensive Cancer Center
2010-present: Associate Professor and ChairDepartment of Biomedical Informatics, The Ohio State University
2010-present: Executive DirectorThe Ohio State University, Center for IT Innovation in Healthcare
Payne, P.R.O.
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Professional Appointments:
1995-1999: Lead Programmer and Systems AnalystHamilton Glaucoma Center, University of California - San Diego
2000-2003: Director of Biomedical Informatics
CLL Research Consortium, Moores Comprehensive Cancer Center,
University of California - San Diego
2006-present: Translational Research Informatics Architect
The Ohio State University Medical Center
University Committee Assignments:
2005-2006 Graduate School Advisory Committee
Columbia University, Graduate School of Arts and Sciences
2005-2006 Graduate Admissions Committee
Columbia University, Department of Biomedical Informatics
2006-2008 Clinical and Translational Science Award Planning Committee
The Ohio State University Medical Center
2006-2008 Systems Committee
The Ohio State University, Department of Biomedical Informatics
2006-Present Faculty Search Committee
The Ohio State University, Department of Biomedical Informatics
2007-Present Clinical Trials Management System Task Force (Co-Chair)
The Ohio State University Medical Center
2007-Present Research Information Systems Steering Committee
The Ohio State University Medical Center
2007-Present HIPAA Privacy and Security Committee
The Ohio State University Medical Center
2008-Present Center for Clinical and Translational Science Executive Committee
The Ohio State University
2009-Present Promotion Credit and Criteria for Team Science Task Force
The Ohio State University, College of Medicine
2010-Present Research Computing Steering Committee
The Ohio State University
2010-Present Rules and Bylaws Committee
The Ohio State University, College of Medicine
Payne, P.R.O.
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Professional Organizations:
American Medical Informatics Association (AMIA)
Association for Computing Machinery (ACM)
American Association for the Advancement of Science (AAAS)
Peer Review:
Journals (Editorial Board):
2007-Present Biomedical Informatics Insights
Journals (ad hoc):
2007-Present Journal of the American Medical Informatics Association (JAMIA)
2007-Present Journal of Biomedical Informatics (JBI)
2009-Present BMC Medical Informatics and Decision Making
2009-Present Artificial Intelligence in Medicine
2010-Present Applied Clinical Informatics
Symposia (Scientific Program Committee):
2009 - Present AMIA Summit on Translational Bioinformatics
Awards and Honors:
1995 California Biomedical Research Association Scholarship
1995 University of California Academic Achievement Scholarship
2003 Distinguished Poster, AMIA Annual Symposium
2004 Apple World Wide Developers Conference Student Scholarship
2007 Nominated to Bio-Ohio Thirty in Their 30 s
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PART II:
Research, Teaching, and Clinical Contributions
Research Narrative:
In order to fully realize the promise of translational research and personalized
medicine, it is
necessary to couple high-throughput biomarker and phenotypic information sources, and
reason
upon resulting integrative data sets. In this context, translational research can be
defined as
both the testing of novel therapeutic strategies (in humans) that were developed through
basic
laboratory experimentation and taking observations from the bedside-to-the-bench .
Similarly, personalized medicine can be defined as the use of genetic susceptibility or
pharmacogenetic testing to tailor an individual's preventive care or drug therapy . The
benefits
of these approaches to biomedical research and healthcare delivery focus primarily on the
ability
to predict risk profiles of individual patients for both the development and progression
of
disease, and subsequently plan for and deliver adaptive preventative and therapeutic
interventions based upon an understanding of how a patient s unique phenotype and bio-
molecular profile will influence their response to such treatment modalities. Over the
last
several years, there has been a significant focus on the development of novel, high-
throughput
bio-molecular data generation and management methods and platforms. However, similar
attention has not been placed upon the development of high-throughput phenotyping
approaches.
Given the increasing availability of potential sources for phenotype data, such as
electronic
health record systems and clinical trial management systems, the need for the development
and
validation of informatics methods for such phenotyping is critical. It is this gap in
knowledge
that motivates the following research focus areas within my laboratory:
The development and evaluation of systems-level architectures and socio-technical
models related to the efficient conduct of clinical and translational studies involving
high-throughput phenotyping;
The design of integrative translational research information management systems
that incorporate clinical trial and bio-specimen management functionality with service-
oriented electronic data interchange modalities in order to increase the scope, quality
and
fidelity of ensuing data repositories, and the measurement of the impact of such systems
on research productivity; and
The application of conceptual knowledge engineering techniques to support high-
throughput hypothesis generation in multi-dimensional biomedical data sets, and the
identification and evaluation of the characteristics of such hypotheses that correspond
to
their perceived and realized validity and ability to inform novel study designs.
The motivating hypothesis underlying these aims is that increased phenotyping throughput
and
quality in both single and multi-site clinical and translational research programs will
be made
possible through the use of a combination of: 1) distributed computing platforms for
electronic data interchange between heterogeneous data sources; 2) conceptual knowledge
engineering tools and techniques; and 3) rigorous planning and evaluation of information
technology deployment and adoption using socio-technical methods and systems-level
frameworks.
Payne, P.R.O.
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Research Funding:
2006-2011National Cancer Institute (PO1 Award)
Role: Co-Investigator, Biomedical Informatics Program Director
Title:
Chronic Lymphocytic Leukemia Research Consortium2008-2013National Center for Research Resources (CTSA
)
Role:
Co-Investigator, Biomedical Informatics Program Director
Title: OSU Center
for Clinical and Translational Science
2008-2012National Cancer Institute (R01 Award)
Role: Principal Investigator
Title: Re-Engineering the CRC Integrated Information Management System
2008-2012National Library of Medicine (R01 Award)
Role: Co-Investigator
Title: Evaluating EHR-based, Point-of-Care Trial Recruitment
2009-2011National Cancer Institute / Booz Allen Hamilton (Contract)
Role: Principal Investigator
Title: OSU Cancer Center Getting Connected With caBIG Project
2009-2011National Library of Medicine (R01/EUREKA/ARRA Award)
Role: Co-Principal Investigator
Title: OAMiner - knowledge-anchored discovery, verification and validation
of hypotheses from heterogeneous data sources
2009-2011National Center for Research Resources (CTSA Administrative Supplement)
Role: Co-Principal Investigator
Title: The Translational Research Informatics and Data Management
(TRIAD) Grid Project
2009-2014National Cancer Institute (P50 SPORE Award)
Role: Co-Investigator, Biomedical Informatics Core Director
Title: Experimental Therapeutics of Leukemia
2010-2015National Cancer Institute (R01 Award)
Role: Co-Investigator
Title: Assays for Screening Histone Modifications in Cancer
Payne, P.R.O.
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Teaching Activities:
1. Columbia University Medical Center
Courses:
2004 Course Title: Interactive Healthcare Communication
School: School of Nursing
Role: Lecture Teaching Assistant, Laboratory Instructor
2005 Course Title: Theory and Methods in Biomedical Informatics
School: Graduate School of Arts and Sciences
Role: Lecture Teaching Assistant, Laboratory Instructor
Trainees Supervised:
2006-2007 Amy Chused, Post-doctoral Trainee (Biomedical Informatics)
2006-2007 James Deitzer, Masters Candidate (Biomedical Informatics)
2. The Ohio State University Medical Center
Courses:
2006-Present Course Title: Advanced Topics in Biomedical Data Management
School: College of Medicine
Role: Guest Lecturer
2007-Present Course Title: Bioinformatics Applied to Humans
School: College of Medicine
Role: Guest Lecturer
2007-Present Course Title: Advanced Topics in Biomedical Informatics
School: College of Medicine
Role: Guest Lecturer
2007-Present Course Title: Foundational Knowledge Nursing and Health Systems
School: College of Nursing
Role: Guest Lecturer
2007-Present Course Title: Healthcare Information Systems
School: School of Allied Medical Professions
Role: Guest Lecturer
2008-Present Course Title: Seminar in Biomedical Informatics
School: College of Medicine
Role: Course Director
2010-Present Course Title: Introduction to Clinical Informatics
School: College of Medicine
Role: Course Director
Payne, P.R.O.
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Teaching Activities (Continued):
Trainees Supervised:
2006-2007Shirley Luong, Doctoral Candidate
(IBGP)
2008-2009Kristin Circle, Masters of Science Candidate
(IBGP/Pathology)
2008-2009Tyler Wagner,
Undergraduate Nursing Student
2008-2009Taylor Pressler, Masters of Science Candidate
(Statistics)
2008-PresentKishore Jayanti,
Medical Student
2009-PresentJoe Schultz, Doctoral Candidate
(Biophysics)
2010-PresentMarcelo Lopetegui, Visiting Scholar (Chile)
3. Other Teaching Activities
2009-Present Course: Introduction to Clinical Research Informatics
Venue: AMIA 10x10 Program (Distance Learning)
Role: Lecturer
2009-Present Course: Clinical Research Informatics Theory, Methods, and Best Practices
Venue: AMIA Spring Congress (Tutorial)
Role: Tutorial Director, Instructor
2009-Present Course: Clinical Research Informatics Theory, Methods, and Best Practices
Venue: AMIA Annual Symposium (Tutorial)
Role: Tutorial Director, Instructor
Payne, P.R.O.
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Community Service:
2003-2004Consultant, Institute of Medicine, Clinical Research Roundtable
2003-2006Consultant, CLL Research Consortium
2006-2008 Leadership Committee, AMIA Clinical Research Informatics Working Group
2007-Present Co-Chair, AMIA Clinical Research Informatics Steering Task Force
2008-2009Consultant, Emory University, Center for Comprehensive Informatics
2008-2009Consultant, University of North Carolina
Chapel Hill, CTSA Program
2008-PresentSecretary,
AMIA Clinical Research Informatics Working Group
2008-Present Advisory Board, University of California Irvine, ICTS
2008-Present Advisory Board, Virginia Commonwealth University, CTSA Planning
Committee
2008-Present Advisory Board, Research Centers in Minority Institutes Consortium (RCMI)
2009-PresentSPC Member, AMIA Translational Bioinformatics Summit
2009 SPC Track Chair, AMIA Spring Congress
2009-Present Operations Committee, CTSA Informatics Key Function Committee (IKFC)
2009-2010 SPC Track Chair, Summit on Clinical Research Informatics
2009-Present Steering Committee, Workshop on Interactive Systems in Healthcare (WISH)
2010-Present SPC Chair, AMIA Clinical Research Informatics Summit
2010-PresentNLM, Informatics for in silico Discovery Advisory Committee 2010-Present
Advisory Board, Case Western Reserve University / Cleveland Clinic CTSA
Presentations at International Conferences:
2003 AMIA Annual Symposium
Washington, D.C.
2004 MEDINFO
San Francisco, California
2006 CHI 2006: Conference on Human Factors in Computing Systems
Montreal, Quebec, Canada
2007 AMIA Annual Symposium
Washington, D.C.
Invited Seminars and Presentations:
2000 Update of Medical Informatics
San Diego State University, Department of Public Health
2001 Clinical Research Information Management
M.D. Anderson Cancer Center, Leukemia Department
2002 Information Management in the CLL Research Consortium
National Cancer Institute, Cancer Therapy Evaluation Program
Information Management in the CLL Research Consortium
Columbia University, Department of Biomedical Informatics
Clinical Research Information Management
San Diego Telecom Council
2004 Tissue and Data Repositories and HIPAA
Columbia University Bioethics Program
Dangers in the Cyber Cafe
Columbia University Bioethics Program
A Practical Guide to HIPAA Compliance in Tissue Banking
Columbia University Bioethics Program
2005 Biomedical Informatics at the Intersection of Clinical and Laboratory Services
University of California at San Diego Medical Center
Privacy & Confidentiality in Research
Columbia University Bioethics Program
2007 Human Subjects Protection in Social and Behavioral Research
Columbia University IRB Training Symposium
Payne, P.R.O.
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Invited Seminars and Presentations (Continued):
Leveraging Enterprise Data Warehousing to Support Translational Research
University of Cincinnati
The Value of Integrative Informatics Platforms
Moores UCSD Cancer Center
Enterprise Data Warehousing to Support Clinical and Translational Research
NSF Workshop: Expanding Secondary Use of Health Data
Semantic Interoperability in Translational Research
The Ohio State University, IT Innovations in Healthcare Symposium
2008 Challenges and Opportunities in Translational Research Informatics
Arizona State University, Department of Biomedical Informatics Seminar
Catalyzing Translational Research: Integrative Biomedical Informatics Platforms
University of Cincinnati
Catalyzing Translational Research Using Integrative Biomedical Informatics
UC Irvine, Institute for Clinical and Translational Science Seminar
Catalyzing Translational Research Using Integrative Biomedical Informatics
Virginia Commonwealth University
Research Collaborations in Health Care
The Ohio State University, Advances in Health Care through Data Analytic
Symposium
2009 Integrating Enterprise Research Systems and Epic
Epic Research Advisory Council (Madison, WI)
Catalyzing Translational Research Using Integrative Biomedical Informatics
University of North Carolina at Chapel Hill
The High Throughput Data Problem: Hypothesis Generation and Phenotype
Modeling in Translational Research
Ohio Collaborative Conference on Bioinformatics 2009 (Cleveland, OH)
caBIG and CTSA: Advancing Translational Research Using Integrative
Biomedical Informatics Platforms
caBIG Annual Meeting (Washington, D.C.)
Payne, P.R.O.
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Invited Seminars and Presentations (Continued):
The High Throughput Data Problem: Hypothesis Generation and Phenotype
Modeling in Translational Research
University of Chicago
The High Throughput Data Problem: Hypothesis Generation and Phenotype
Modeling in Translational Research
Indiana University / Purdue University
2010 TRIAD: The Translational Research Informatics and Data Management Grid
Cleveland Clinical and Translational Science Collaborative (Cleveland,OH)
The TRITON Project: An Integrative Platform for Clinical and Translational
Research
CLL Research Consortium Annual Meeting (Washington, DC)
The High Throughput Data Problem: Hypothesis Generation and Phenotype
Modeling in Translational Research
University of Texas Medical Center (Houston, TX)
Biomedical Informatics: Enabling a Learning Healthcare System
American Academy of Optometry Summer Research Institute (Columbus, OH)
The OAMiner Project: An Integrative Informatics Platform for Hypothesis
Generation and in silico Science
National Library of Medicine Informatics for in silico Discovery Workshop
(Bethesda, MD)
Payne, P.R.O.
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