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CHENGCHENG HU

University of Arizona Phone: 520-***-****

Mel and Enid Zuckerman College of Public Health E-mail: abo4ae@r.postjobfree.com.edu1295 N. Martin A228

Campus P. O. Box 245211

Tucson, AZ 85724

CHRONOLOGY OF EDUCATION

2001 Ph.D. in Biostatistics, University of Washington, Seattle, WA

Dissertation: Semiparametric failure-time regression with mismeasured

or missing covariates

Advisor: Dr. Danyu Lin

1998 M.S. in Biostatistics, University of Washington, Seattle, WA

1995 M.A. in Mathematics, Johns Hopkins University, Baltimore, MD

19901993 Undergraduate Study in Mathematics, Peking University, Beijing, China

CHRONOLOGY OF EMPLOYMENT

Academic Positions

2008presentAssistant Professor, Public Health, Division of Epidemiology and

Biostatistics, Mel and Enid Zuckerman College of Public Health,

University of Arizona, Tucson, AZ

2008present Member, Graduate Interdisciplinary Program in Statistics,

University of Arizona, Tucson, AZ

2008present Member, BIO5 Institute, University of Arizona, Tucson, AZ

20022008Assistant Professor of Biostatistics, Department of Biostatistics,

Harvard School of Public Health, Boston, MA

20012008Senior Statistician, Center for Biostatistics in AIDS Research,

Harvard School of Public Health, Boston, MA

20012002 Postdoctoral Research Fellow, Department of Biostatistics,

Harvard School of Public Health, Boston, MA

19962001Research Assistant, Fred Hutchinson Cancer Research Center,

Seattle, WA

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1999Teaching Assistant, Department of Biostatistics,

University of Washington, Seattle, WA

19931996Teaching Assistant, Department of Mathematics,

Johns Hopkins University, Baltimore, MD

OtherExperience

2008presentConsultant, Center for Biostatistics in AIDS Research,

Harvard School of Public Health, Boston, MA

1999Intern and Visiting Scientist, Genentech, Inc.,

South San Francisco, CA

HONORSANDAWARDS

1999 Best Written Paper, Student Paper Competition

International Biometric Society (WNAR)

1998 Donovan J. Thompson Award for Academic Excellence in Biostatistics,

University of Washington, Seattle, WA

19931996Tuition Fellowship, Johns Hopkins University, Baltimore, MD

1989 Finalist and Third-Prize Winner, Chinese Mathematics Olympiad

SERVICE/OUTREACH

ExternalService

Member, Adolescent Research Agenda Committee, Pediatric AIDS Clinical Trials

Group, 2006.

Member, NIH/NCI Small Grants for Cancer Epidemiology (R03) Review Panel,

April, 2009; June, 2009; October, 2009; April, 2010; June, 2010.

Reviewer, James and Esther King Biomedical Research Program administered

by the Florida Department of Health, February, 2010.

Member, Program Faculty, Sequencing the Genome: Implications for Cancer

Therapy, A Primer for the Practicing Physician, Phoenix, AZ, February, 2011.

Reviewer, Bankhead-Coley Cancer Research Program, Florida Department of

Health, October, 2011

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Reviewer, Bankhead-Coley Cancer Research Program, Florida Department of

Health, January, 2012

ProfessionalSocieties

American Statistical Association

International Biometric Society (WNAR)

RefereeService

InternalService

Harvard School of Public Health:

Colloquium Committee, Dept. of Biostatistics, 2002-2004, 2005-2007.

Curriculum Committee, Dept. of Biostatistics, 2002-2003, 2007-2008.

Postdoctoral Committee, Dept. of Biostatistics, 2002-2003, 2004-2005, 2006-

2007.

Hiring Committee, Center for Biostatistics in AIDS Research, 2003-2006.

Newsletter Committee, Dept. of Biostatistics, 2003-2004.

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Qualifying Exam Committee, Dept. of Biostatistics, 2003-2004.

Teaching Effectiveness Committee, Dept. of Biostatistics, 2003-2005.

Diversity Committee, Dept. of Biostatistics, 2004-2005.

Webpage Committee, Dept. of Biostatistics, 2005-2008.

Admission and Recruiting Committee, Dept. of Biostatistics, 2006-2007.

University of Arizona:

Colloquia & Forums Committee (Chair), Graduate Interdisciplinary Program in

Statistics, 2008-2009

ResearchAdvisoryCommittee,MelandEnidZuckermanCollegeofPublicHealth,

2008-present

Biostatistics Admissions, Division of Epidemiology and Biostatistics, Mel and Enid

Zuckerman College of Public Health, 2009-present

Website Workgroup, Division of Epidemiology and Biostatistics, Mel and Enid

Zuckerman College of Public Health, 2010

Peer Review Committee, Division of Epidemiology and Biostatistics, Mel and Enid

Zuckerman College of Public Health, 2011

Biostatistics Search Committee, Division of Epidemiology and Biostatistics, Mel

and Enid Zuckerman College of Public Health, 2011-present

ExecutiveCommittee,GraduateInterdisciplinaryPrograminStatistics,2011-present

Curriculum Committee (Chair), Graduate Interdisciplinary Program in Statistics,

2011-present

PUBLICATIONS/CREATIVEACTIVITY

Peer-ReviewedPublications

(* derived from dissertation)

1. Etzioni RD, Feuer EJ, Sullivan SD, Lin DY,HuC, and Ramsey SD (1999). On

theuseofsurvivalanalysistechniquestoestimatemedicalcarecost.Journal

of Health Economics18(3), 365 80.

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2. Etzioni RD, Pepe MS, Longton G,HuC, and Goodman GE (1999). Incorpo-

rating the time dimension in receiver operating characteristic curves: a case

study of prostate cancer.Medical Decision Making19(3), 242-51.

3. Ellis WJ, Etzioni RD, Vessella RL, HuC, and Goodman GE (2001). Serial

prostatespecificantigen,free-to-totalprostatespecificantigenratioandcom-

plexed prostate specific antigen for the diagnosis of prostate cancer.Journal

of Urology166(1), 93-8; discussion 98-9.

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P1021 Study Team (2007). Long term safety and efficacy of a once-daily

regimen of emtricitabine, didanosine, and efavirenz in HIV-infected, therapy-

naive children and adolescents (Pediatric AIDS Clinical Trials Group protocol

P1021).Pediatrics, 2007; 120, e416-e423.

17. Healy BC, De Gruttola VG, and HuC (2008). Accommodating uncertainty

in tree set for function estimation. Statistical Applications in Genetics and

Molecular Biology, 7, Iss. 1, Article 5.

Available at: http://www.bepress.com/sagmb/vol7/iss1/art

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21. WeinbergA,DickoverR,BrittoP,HuC,Patterson-BartlettJ,KraymerJ,Gutz-

manH,ShearerW,GelmanR,RathoreM,McKinneyR,andthePACTG1021

Team(2008). ContinuousimprovementintheimmunesystemofHIV-infected

children on prolonged antiretroviral therapy.AIDS, 22(17), 2267-2277.

22. Garvie PA, Cremeens J, Gaur AH, Flynn PM, Belzer M, McSherry G, and

HuC for the Pediatric AIDS Clinical Trials Group 1036A Study Team (2009).

Development of a directly observed therapy adherence intervention for ado-

lescents with Human Immunodeficiency Virus-1

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37. Hibler EA,HuC, Jurutka PW, Mart'inez ME, and Jacobs ET (2011). Polymor-

phic variation in GC and CASR and associations with Vitamin D metabolite

concentration and metachronous colorectal neoplasia.Cancer epidemiology,

biomarkers & prevention, accepted.

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BookChapter

1. WangWandHuC (2006). Proportionalhazardsregressionmodels.Springer

Handbook of Engineering Statistics (Pham H, editor), 387-395. New York:

Springer-Verlag, Inc.

OtherPublication

(* derived from dissertation)

1. *HuC and Lin DY (2000). Corrected imputation method for Cox regression

with missing covariates.Proceedings of the American Statistical Association,

Biometrics Section, 2000.

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(2011). Hyaluronan deposition correlates with poor

survival in pancreatic cancer. AACR 102nd Annual Meeting, Orlando, FL.

22. Hibler EA, HuC, Jurutka PW, Mart'inez ME, Wagoner CL, and Jacobs ET

(2011). Effect of over-the-counter vitamin D supplementation on circulating

25-hydroxyvitamin D concentration.Cancer Prevention Research2011; 4(10

Suppl):B103.

SCHOLARLYPRESENTATIONS

ConferencePresentations

HuC and Lin DY: Cox regression with covariate measurement error, 1999 Inter-

national Biometric Society (WNAR) Meeting, Seattle, WA (contributed).

HuC and Lin DY: Cox regression with covariate measurement error, International

Biometric Conference 2000, Berkeley, CA (contributed).

HuC and Lin DY: Corrected imputation method for Cox regression, 2000 Joint

Statistical Meetings, Indianapolis, IN (contributed).

HuC and Lin DY: Analysis of recurrent event data with covariate measurement

error, 2002 International Biometric Society (ENAR) Meeting, Crystal City, VA

(contributed).

HuC and De Gruttola V: Joint modeling of interval censored HIV mutations and

failuretimedata,2008InternationalBiometricSociety(ENAR)Meeting,Crys-

tal City, VA (invited).

HuC and De Gruttola V: A U-statistic based random forest approach for longitudi-

nal markers, 2011 Joint Statistical Meetings, Miami Beach, FL (contributed).

InvitedColloquiaandSeminars

Cox regression with covariate measurement error, Genentech, Inc., South San

Franciscon, CA, 1999.

Cox-type regression with covariate measurement error, St. Jude Children s Re-

search Hospital, 2000.

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Coxregressionwithmismeasuredormissingcovariates,DepartmentofStatistics,

North Carolina State University, 2001; Department of Statistics, University

of Illinois at Urbana-Champaign, 2001; Division of Biostatistics, Ohio State

University, 2001; Department of Biostatistics, University of Michigan, 2001;

Department of Statistics, Florida State University, 2001; Department of Bio-

statistics, HarvardSchoolofPublicHealth, 2001; DepartmentofBiostatistics,

University of North Carolina, 2001; Division of Biostatistics, Indiana Univer-

sity, 2001; Division of Biostatistics, University of Texas, 2001; Department of

Biostatistics, Boston University, 2001; Department of Oncology, Johns Hop-

kins University, 2001; Department of Epidemiology and Biostatistics, Univer-

sity of California, San Francisco, 2001.

Joint modeling of HIV resistance mutations and failure time data, Division of Bio-

statistics, Yale School of Public Health, New Haven, CT, 2004.

Joint modeling of progression of HIV resistance mutations measured with uncer-

tainty and failure time data, Department of Statistics, University of Missouri,

Columbia, MO, 2006.

Recursive partitioning methods in the study of HIV resistance mutations, Mas-

sachusetts General Hospital, Boston, MA, 2007; Children s Hospital Boston,

Boston, MA, 2008; University of Arizona Mel and Enid Zuckerman College of

Public Health, 2008.

Recursive partitioning in the analysis of longitudinal markers, Arizona Cancer

Center, Tucson, AZ, 2008.

Time-varying trees in the study of HIV resistance mutations, University of Arizona

Mel and Enid Zuckerman College of Public Health, Tucson, AZ, 2011.

A random forest approach for longitudinal markers and unobserved haplotypes,

University of Arizona Mel and Enid Zuckerman College of Public Health, Tuc-

son, AZ, 2012.

GRANT

CurrentGrants (funding amount is for most recent year if not indicated otherwise)

NIH/NCI P01CA027502 (PI: Alberts), 7/1/11 6/30/16, $942,451

Chemoprevention of Skin Cancer Program Project

Role: Director of Biometry Core (15% FTE)

TheBiometryCoreprovidesstatisticalanddatamanagementsupporttoallprojects

andothercoresofthisgrant,andasauniqueexpertiseprovidessupporttoclinical

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trials involving karyometric endpoints. As the core director I oversee all aspects

of this core, integrate core activities with the grant objectives, participate in study

design and monitoring, lead all data analysis efforts, and co-author manuscripts.

In addition, I develop new statistical methods for the analysis of karyometric data.

NIH/NCI P30CA23074 (PI: Alberts), 7/1/09 6/30/14, $235,264

Arizona Cancer Center Support Grant

Role: Co-Investigator (2% FTE)

MyworkistoprovidestatisticalsupportforresearchattheArizonaCancerCenter.

NIH/NCI 5U01 CA128454 (PI: Cunningham), 7/1/09 - 6/30/11, $65,596

Tumor Glycomics Laboratory for Pancreatic Carcinoma

Role: Co-Investigator (2% FTE)

My work is to provide statistical expertise for the analysis of newly developed

glycomic biomarkers.

CDC/NIOSH 1R01OH009469 (PI: Burgess), 9/1/09 8/31/13, $337,026

Implementing Risk Management Strategies To Prevent Injuries Among Firefight-

ers

Role:

Co-Investigator (10% FTE)

My work is to provide statistical expertise for all aspects of this grant.

FEMA AFG (PI: Burgess), 4/23/10 4/22/13, $1,000,000 (3-year)

Firefighter Statin Trial

Role:

Co-Investigator (10% FTE)

My work is to provide statistical expertise for the design, conduct, and data anal-

ysis of this clinical trial.

NIH/NCI 1U01CA153086-01 (PIs: Mart'inez and Futscher), 9/17/10 8/31/15,

$321,936

Epigenetic Features of Pregnancy-Associated Breast Cancer in Hispanic Women

Role:

Co-Investigator (5% FTE)

My work is to provide statistical expertise for all aspects of this grant.

NIH/NIAMS R21AR060811 (PI: Chen), 10/1/11 9/30/13

A New Hip Fracture Risk Prediction Tool Based on Common Predictors and Hip

Geometry

Role: Co-Investigator

My work is to provide statistical expertise for this grant.

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CompletedGrants

NIH/NIAIDR01AI051164(PI:DeGruttola; SubcontractPI:Hu),7/1/09 11/30/11,

$56,591

Methods for Long-Term Follow-Up of HIV-Infected Patients

Role: Principal Investigator of University of Arizona subcontract (25 30% FTE)

My work is to develop novel high-dimensional statistical methods to investigate

the relationship between high dimensional genetic and genomic information with

clinical outcomes.

NIH/NCI P01CA027502 (PI: Alberts), 10/1/08 12/31/10, $750,000

Chemoprevention of Skin Cancer Program Project

Role: Director of Biometry Core (17% FTE before 2/1/10; 0% FTE during the

bridging period 2/1/10 12/31/10)

As the core director I oversaw all aspects of this core, integrated core activities

withthegrantobjectives,participatedinstudydesignandmonitoring,leadalldata

analysis efforts, and co-authored manuscripts.

NIH/NCI P01CA109552 (PI: Von Hoff), 7/1/09 8/31/10, $65,000

Targets to Therapeutics in Pancreatic Cancer

Role: Co-Director of Pattern Analysis and Computational Biology Core (8 12%

FTE)

As a co-director of this core I oversaw all statistical activities of this grant, partici-

pated in study design, conducted data analysis, and co-authored manuscripts.

CDC/NIOSH 200-****-***** (PI: Burgess), 1/1/09 11/1/09, $12,600

Development of a Severe Injury Surveillance System for Hazard Identification and

Guiding Technological Interventions

Role: Co-Investigator (10% FTE)

My work was to provide statistical expertise for this grant.

NIH U01AI068616 (PI: Fenton), 6/29/06 6/30/08

Statistical and Data Management Center - International Maternal Pediatric Ado-

lescent AIDS Clinical Trials Group

Role: Senior Statistician (50 90% FTE)

Myworkwastoprovidestatisticalexpertiseandleadershipinthedesign,conduct,

and analysis of clinical trials.

NIH R01AI051164 (PI: De Gruttola), 7/1/04 12/31/07

Methods for Long-Term Follow-Up of HIV-Infected Patients

Role: Co-Investigator (25 40% FTE)

My work was to develop novel statistical methods for the study of HIV resistance

mutations.

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NIH U01AI041110 (PIs: Hughes, Fenton), 9/1/01 6/28/06

Statistical and Data Management Center - Pediatric AIDS Clinical Trials Group

Role: Senior Statistician (45

60% FTE)

Myworkwastoprovidestatisticalexpertiseandleadershipinthedesign,conduct,

and analysis of clinical trials.

R37AI024643 (PI: Lagakos), 9/1/01 6/30/04

Statistical Methods in AIDS Research

Role: Co-Investigator (25% FTE)

My work was to conduct research in statistical methodology.

This is a true and accurate statement of my activities and accomplishments. I

understand that misrepresentation in securing promotion and tenure may lead to

dismissal or suspension under ABOR Policy 6-201 J.1.b.

Chengcheng Hu

January, 2012

Contact this candidate