Medical School
Resume:
CURRICULUM VITAE
PAUL J. BOBROWSKI
ADDRESS:
Rainforest Nutritionals, Inc. Voice: 919-***-****
Park Labs LLC 919-***-****
Santerra Pharmaceuticals, Inc. Fax: 919-***-****
**** ********* ****, Suite 120C Cell: 919-***-****
Raleigh, NC 27613 Email: abnlf3@r.postjobfree.com
PROFESSIONAL EXPERIENCE:
2008-Present Consultant: cGMP Mira Health Products, Ltd: Farmingdale, NY
2005-Present Managing Member Park Labs, LLC: Raleigh, NC
2004-Present President Santerra Pharmaceuticals, Inc: Raleigh, NC
2002-Present President, COO Rainforest Nutritionals, Inc: Raleigh NC
2001-2002 Laboratory Director Allvia Integrative Healthcare, Inc: Phoenix, AZ
2000-2000 Clinical Coordinator Gold River Pharma, Ltd: Wanchai, Hong Kong, PRC
1999-2002 COO, JV Coordinator Rainforest Phytoceuticals, LLC: Albany, NY
1998-2001 Research Associate Albany Medical College, Pediatrics: Albany, NY
1993-1998 Research Associate LSU Medical School, Neonatology: New Orleans, LA
1993-1995 Medical Editor Tulane Medical School, Ophthalmology: New Orleans, LA
1987-1993 Research Assistant Tulane Medical School, Ophthalmology: New Orleans, LA
EDUCATION & SPECIALIZED TRAINING:
1999 DSHEA AFDO-FDA: Denver, CO
1999 AALAC-IACUC Albany Medical College; Albany, NY
1998 Electrochemical Analysis LSU Medical School: New Orleans, LA
1998 Capillary Electrophoresis LSU Medical School: New Orleans, LA
1993 HPLC-ECD LSU Medical School: New Orleans, LA
1993 HPLC Waters Corp: New Orleans, LA
1993 OSHA, SOP, GLP LSU Medical School: New Orleans, LA
1992 BA - Minors Chemistry, Biology University of New Orleans: New Orleans, LA
1988 In Vitro Diagnostics Tulane Medical School: New Orleans, LA
Biochemical analysis, Synthesis &
1988-1999 Extraction, Infectious Agent Various
Protocols, Surgery
PROFESSIONAL LICENSURE:
1995-1999 Clinical Laboratory Scientist LA Board Medical Examiners: New Orleans, LA
(License #S00246)
RESEARCH SUPPORT:
2004-2005: National Institutes of Health/Aging (NIH/NIA): Small Business Innovation Research
(SBIR). “Enhanced IGF-1 Production by Human Cartilage.” 1R43AG024733-01. Panel:
Center for Scientific Review Special Emphasis. $99,500 (PI: PJ Bobrowski)
Bobrowski, PJ: CV
Page 2 of 4
REFEREED PUBLICATIONS:
1. Miller MJ, Bobrowski P, Shukla M, Gupta K, Haqqi TM: Chondroprotective effects of a proanthocyanidin
rich Amazonian genonutrient reflects direct inhibition of matrix metalloproteinases and upregulation of IGF-1
production by human chondrocytes. Journal of Inflammation, 2007, 4:16.
2. Miller MJ, Ahmed S, Bobrowski P, Haqqi TM: The chrondoprotective actions of a natural product are
associated with the activation of IGF-1 production by human chondrocytes despite the presence of IL-1beta.
BMC Complementary and Alternative Medicine, 2006, 6:13.
3. Miller MJ, Mehta K, Kunte S, Raut V, Gala J, Dhumale R, Shukla A, Tupalli H, Parikh H, Bobrowski P,
Chaudhary J: Early relief of osteoarthritis symptoms with a natural mineral supplement and a herbomineral
combination: a randomized controlled trial [ISRCTN38432711]. Journal of Inflammation, 2005, 2:11.
4. Bobrowski P: The Straight Dope on Ephedra. MLM Press, April 2003.
5. Bobrowski P, Chan C, Ho K, Miller MJS: Efficacy and tolerance of a botanical and nutrition-based weight
management system in an Asian population. Journal of the American Nutraceutical Association, 2002, 5:34-
40.
6. Sandoval M, Okuhama N, Zhang XJ, Condezo LA, Lao J, Angeles FM, Musah RA, Bobrowski P, Miller MJS:
Anti-inflammatory and antioxidant activities of cat's claw (Uncaria tomentosa and Uncaria guianensis) are
independent of their alkaloid content. Phytomedicine, 9:325-37, 2002.
7. Miller MJS, Angeles FM, Reuter BK., Bobrowski P, Sandoval M: Dietary antioxidants protect gut epithelial
cells from oxidant-induced apoptosis. BMC Complementary and Alternative Medicine, 2001, 1:11.
8. Miller MJ, MacNaughton WK, Zhang XJ, Thompson JH, Charbonnet RM, Bobrowski P, Lao J, Trentacosti
AM, Sandoval M: Treatment of gastric ulcers and diarrhea with the Amazonian herbal medicine sangre de
grado. American Journal of Physiology, Gastrointestinal and Liver Physiology, 2000. 279:192-200.
9. Penn D, Zhang L, Bobrowski PJ, Quinn M, McDonough KH: Carnitine deprivation adversely affects cardiac
performance in the lipopolysaccharide- and hypoxia/reoxygenation-stressed piglet heart. Shock, 1999,
11(2):120-6.
10. Schmidt-Sommerfeld E, Bobrowski PJ, Penn D, Rhead WJ, Wanders RJ, Bennett MJ: Analysis of carnitine
esters by radio high-performance liquid chromatography in cultured skin fibroblasts from patients with
mitochondrial fatty acid oxidation disorders. Pediatric Research, 1998, 44:210-14.
11. Penn D, Bobrowski PJ, Quinn M, McDonough K: Fatty Acids exacerbate impairment of cardiac performance
in the carnitine-deprived piglet. Journal of the Federation of American Societies for Experimental Biology,
1998, 12:2978.
12. Martinez-Triana BT, Bobrowski PJ, Sulaeman E, Williams JD, Schmidt-Sommerfeld E, Penn D: Dietary
medium-chain triglycerides (MCI) increase biliary excretion of carnitine in the neonatal piglet. Journal of the
Federation of American Societies for Experimental Biology, 1998, 12:2979.
13. Penn D, Zhang L, Bobrowski PJ, Quinn M, Liu X, McDonough KH: Carnitine deprivation adversely affects
cardiovascular response to bacterial endotoxin (LPS) in the anesthetized neonatal pig. Shock, 1998, 10:377-82.
14. Penn D, Bobrowski PJ, Zhang L, Schmidt-Sommerfeld E: Neonatal nutritional carnitine deficiency: a piglet
model. Pediatric Research, 1997, 42:114-21.
15. Sulaeman E, Zhang L, Bobrowski PJ, Williams J, Penn D. Intravenous L-carnitine promotes jejunal mucosal
cell proliferation during total parenteral nutrution (TPN) in neonatal pigs. Journal of the Federation of
American Societies for Experimental Biology, 1997, 11:446-47.
16. Penn D, Zhang L, Bobrowski PJ, Quinn M, Liu X, Williams J, McDonough K. Nutritional carnitine deficiency
impairs myocardial function in the neonatal pig. Journal of the Federation of American Societies for
Experimental Biology, 1997, 11:446-47.
Bobrowski, PJ: CV
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17. Penn D, Bobrowski P, Zhang L, Kuvibidila S: Effect of carnitine deprivation on lymphocyte proliferation in
the neonatal piglet. Pediatric Research, 1996, 39:316.
18. Sulaeman E, Bobrowski P, Zhang L, Penn D: Beneficial effect of intravenous L-carnitine supplementation on
jejunal mucosa during total parenteral nutrition in the neonatal piglet. Gastroenterology, 1996. 110:842.
19. Penn D, Bobrowski P, Zhang L and Schmidt-Sommerfeld E: Neonatal nutritional camitine deficiency: a piglet
model. Pediatric Research, 1995, 37(4:2):152.
20. Schmidt-Sommerfeld E, Weinberger MJ, Bobrowski P, Penn D, Bennett MJ: Analysis of carnitine metabolites
in skin fibroblasts facilitates the diagnosis of inborn errors of fatty acid oxidation (IEFAO). Pediatric
Research, 1995, 37:152.
21. Kuvibidila S, Bobrowski P, Zhang L, Penn D: Impaired iron metabolism and reduced immunity in piglets
receiving total parenteral nutrition. Journal of Investigative Medicine, 1995, 43:242-5.
22. Schmidt-Sommerfeld E, Zhang L, Bobrowski P, Penn D: Quantitation of short and medium chain
acylcarnitines in plasma by radioisotopic exchange/high performance liquid chromotography. Analytical
Biochemistry, 1995, 231:27-33.
23. Penn D, Kuvibidila S, Bobrowski P: Effect of halothane on lymphocyte proliferation in the piglet. Pediatric
Research, 1994, 35:167.
24. Penn D, Bobrowski P, Zhang L, Schmidt-Sommerfeld E and Rinaldo P. Effect of halothane on camitine and
glycine conjugation and omega oxidation in the neonatal pig. Journal of the Federation of American
Societies for Experimental Biology, 1994, 8(4):A544.
25. Bobrowski PJ, Capiola R, Centifanto YM: Latent herpes simplex virus reactivation in the guinea pig. An
animal model for recurrent disease. International Journal of Dermatology, 1991, 30(1):29-35.
26. Dutt R, Centifanto YM, Caldwell D, Bobrowski PJ. The toxic effects of commercially used preparations of
topical gentamycin and epinephrine on cultured human corneal endothelial cells. Investigative Ophthalmology
and Visual Science, 1990, 31:146.
27. Caldwell D & Bobrowski P: The growth of human corneal endothelial cells: a system for in vitro
homogeneity. Investigative Ophthalmology and Visual Science, 1990, 31(4):144.
28. Bobrowski P, Stewart B, Centifanto Y and Caldwell D: Eye cosmetics: a medium for transmitting chlamydia
trachomatis. Investigative Ophthalmology and Visual Science, 1990, 31(4):448.
29. Yates F, Bobrowski PJ and Centifanto YM: The prevention of HSV recurrence by prostaglandin synthesis
inhibition. Investigative Ophthalmology and Visual Science, 1989. 30(3):362.
BOOK CHAPTERS:
Miller MJS, Reuter BK, Wallace J, Sharkey K, Bobrowski P. “Mechanistic and clinical assessment of Zangrado®,
an extract of the Amazonian ethnomedicine Sangre de Grado, for the Treatment of Itch.” Itch: Basic Mechanisms
and Therapy. Yosipovitch G, editor. Marcel Dekker; 2003. pp. 311–320.
PATENTS:
1. Bobrowski, P.J., “Methods and preparations of extracts of Uncaria species with reduced alkaloid content,” US
Patent 6 797 286, September 28, 2004.
2. Bobrowski, P.J., “Methods and preparations of the latex from the croton species,” US Patent 7 208 183, April
24, 2007.
3. Bobrowski, P.J., “Pharmaceutical preparations for the treatment of itch, nausea, hyperalgesia and the
complications of opioid agonists,” US Patent Publication 200********, April 8, 2004.
4. Bobrowski, P.J., “Methods and compositions to enhance endogenous IGF production and their uses,” US
Patent Publication 200********, March 8, 2007.
Bobrowski, PJ: CV
Page 4 of 4
PRESENTATIONS:
1. Schmidt-Sommerfeld E, Weinberger MJ, Bobrowski P, Penn D, Bennett MJ: Analysis of carnitine metabolites
in skin fibroblasts facilitates the diagnosis of inborn errors of fatty acid oxidation (IEFAO). Experimental
Biology, 1996. (Washington, DC).
2. Sulaeman E, Bobrowski P, Zhang L, Penn D: Effect of carnitine supplementation on intestinal mucosa in the
parenterally alimented neonatal piglet. FASEB, 1996. (Washington, DC).
3. Penn D, Bobrowski P, Zhang L, Schmidt-Sommerfeld E: Neonatal nutritional carnitine deficiency: a piglet
model. American Society for Pediatric Research, 1995. (San Diego, CA)
4. Penn D, Bobrowski P, Zhang L, Schmidt-Sommerfeld E, Rianaldo P. Effect of halothane on carnitine and
glycine conjugation and omega oxidation in the neonatal pig. American Society for Pediatric Research, 1994.
(Seattle, WA)
5. Kootman R, Centifanto Y, Caldwell D, Bobrowski P. Reactivation of herpes simplex virus in
immunosuppressed rabbits. 23rd Annual CS O'Brien Professorship, 1989. (New Orleans, LA)
6. Bobrowski PJ, Capiola R, Centifanto YM: Latent herpes simplex virus reactivation in the guinea pig: an
animal model for recurrent disease. ARVO, 1989. (Sarasota, FL)
SPEAKING ENGAGEMENTS:
1. Bobrowski, PJ: Veri-Macana™. Ciena Corporation (2005: Tokyo, Japan)
2. Bobrowski, PJ: The Medicine Man. Dr. R. Scruggs, Host; SmartTalk 870, KRLA (2003: Los Angeles, CA)
3. Bobrowski, PJ: The Amazon Diet. The Top Line Group (2002: Phoenix, AZ)
4. Bobrowski, PJ: Carnitine and Fatty Acid Metabolism. Symposium on L-Carnitine, Lonza Inc (2001: Vail, CO)
5. Bobrowski, PJ: Maca. Lou Epton, Host; KLAV Las Vegas Radio (2001: Las Vegas, NV)
6. Bobrowski PJ & Miller M: Healing from the Rainforest. Total Health Talk Television, Klein M & Combs D,
Producers (2001: Los Angeles, CA)
7. Bobrowski, PJ: A Natural, Ephedra-free Weight Loss System. Gold River Pharma Limited. (2000: Wanchai,
Hong Kong, PRC)
8. Bobrowski PJ: Inca Gold Maca®. Adelaide Training College of Complimentary Medicine (1999: Adelaide,
Australia)
9. Bobrowski PJ: Cat’s Claw, Maca and Sangre de grado. International Conference on Herbal Medicine (1999:
Brisbane, Australia)
PROFESSIONAL INTERESTS:
Ethical Nutraceuticals & Genonutrients; OTC-Nutraceutical Combinations; “Concept to Shelf” Research,
Development, Formulation, Manufacturing & Packaging; Standard and Novel Delivery Systems (Edible Film
Strips, Sprays, Softchews, Stick-tube mixes); DSHEA, CFR 111 cGMP, FTC/FDA regulations;
Ethnobotanicals; Clinical trials; method validation.
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