Medical Project

Sarita Nethula

**********@*****.***

Home: 732-***-****

Cell: 732-***-****

Profile

. 5 years of experience in the pharmaceutical industry.

Experience in multi-step organic/monomer/polymer synthesis,

purification and characterization.

. Experience in analytical testing of raw materials and finished

products.

. Hands on experience in HPLC, GC, TLC, UV-VIS, Dissolution,

Viscometer, Titrations, NMR, GPC, TGA and DSC.

. Experience in literature search and publishing scientific papers

and writing laboratory SOP's.

. Develop formulations of drugs with polymers for in vitro and in

vivo studies

. Purification and characterization of raw materials and finished

products using modern spectroscopic (NMR, IR, Mass) and

chromatographic tools (Silica gel column, HPLC).

. Experience in cGMP and cGLP.

. Self -motivated team player with good communication skills with

strong focus on meeting all projects requirements and good problem

solving skills.

. Handle multitasks simultaneously with minimum supervision.

. Supervised and trained junior level chemists/technicians on

laboratory techniques, sample preparation, instrumentation,

documentation, safety, and regulatory compliance.

. Familiarity with Word, Excel, Power point, Waters Empower, Mestrec

software packages.

Education

Masters in Science (Organic Chemistry)

Osmania University, India

May '97 to May '99.

Bachelors in Science

Osmania University, India

May '94 to May '97.

Professional experience

Bezwada Biomedical

R&D Chemist

Mar '10 - Present

Responsibilities:

Synthesis of biodegradable PCL-PLA and PCL-PGA polymers

Conduct titrations for determination of hydroxyl number and

molecular weight for low molecular weight polymers

Characterize molecular weight of the polymers by Inherent viscosity

of polymer solutions using Capillary viscometer

Determine glass transition temperature of the PCL-PLA polymers

using Differential scanning calorimetry (DSC)

Analyze molecular weight of polymers by Gel Permeation

Chromatography (GPC)

Documentation and reporting of analytical data

TyRx Inc.

Scientist

Apr '05 - Feb '10

Responsibilities:

. Develop polymers for drug eluting stents and biodegradable

polymer coverings for Breast Implants

. Design synthetic routes for new monomer and polymers

. Synthesis and scale up of monomers and polymers.

. Perform synthesis, isolation and characterization of

intermediate degradation products, impurities and side products

. Analyze molecular weight of polymers by Gel Permeation

Chromatography (GPC) using Waters (Empower) and Perkin Elmer

instruments

. Develop formulations of Tyrosine based polymers with Rifampin

and Minocycline for medical devices by film casting, dipping and

spraying.

. Determine viscosity of polymer solutions using Brookfield

viscometer

. Analyze samples to support formulation development and stability

program.

. Analyze stability samples

. Conduct in-vitro drug release studies from medical devices by

HPLC using Waters (Empower) and Perkin Elmer instruments

. Documentation and reporting of analytical data.

. Manufacture and analytical testing of medical devices.

. Maintenance of the laboratory equipment.

. Supervise technology transfer from R&D to cGMP production staff.

. Develop and review batch records and log books related to

manufacturing and equipment.

. Conduct analytical testing of drug substances, drug products and

related compounds using HPLC.

. Prepare weekly project updates and maintained notebooks (as per

GMP).

Indian Institute of Chemical Technology, India

Senior Research fellow

May' 02 - Dec'04

Involved in synthesis of components of sex pheromones (semio

chemicals) of

. Musca domestica (Housefly).

. Rhynchophorus (Coconut Beetle).

. Cosmopolitis sordidis (Banana Weevil).

. Lutzoymia longipalpis (Sandfly).

Indian Institute of Chemical Technology, India

Research Fellow

Jan' 00 - Apr'02

Involved in bulk synthesis of semio chemicals of

. Leucinodes orbanalis (Egg plant Fruit and Shoot Borer).

. Groundnut leaf miner.

. Helicoverpa (Cotton pests).

. Sugarcane borer.

Presentations

. Arikha Moses, Archana Rajaram, Qing Ge, Irene Shatova, Sarita Nethula,

William Adams. "Critical Comparison of Prophylactic Intravenous

Antibiotics and AigisRx Shielded Breast Implants: Is IV Antibiotic

Prophylaxis Effective?" Hot Topics Forum, American Society of Plastic

& Reconstructive Surgery Annual Meeting, May 3, 2008.

. William Adams, Satish Pulapura, Qing Ge, Irene Shatova, Archana

Rajaram, Sarita Nethula, Arikha Moses. "Optimizing Breast Implant

Pocket Preparation. New Horizons: Prevention of Experimental

Capsular Contracture in Breast Implants by an Antimicrobial

Impregnated Biodegradable Sleeve: Initial Studies" Hot Topics Forum,

American Society of Plastic & Reconstructive Surgery October 2007

Meeting, Baltimore, MD.

. Rajaram, A.G., Qing; Sarita Nethula; Shatova, Irene; Pulapura, Satish;

Patel, Nikita; Talwar, Ankur. Blends from Novel Poly(esteramides). in

39th Middle Atlantic Regional Meeting of the American Chemical Society

113-114 (Collegeville, PA, 2007).

. Archana Rajaram, Irene Shatova, Sarita Nethula, Satish Pulapura, Qing

Ge, Ankur Talwar & Nikita Patel Blends from novel Poly(ester-

amides). in American Chemical Society, 39th MidAtlantic Regional

Meeting, May 2007

. Archana Rajaram, Qing Ge, Arikha Moses, Sarita Nethula, Satish

Pulapura, Arthur Schwartz & Irene Shatova. Investigation of In-vitro

Drug Release by Tyrosine-Based Resorbable Polymers. in Controlled

Release Society, New York, June 2008

. B.Krishnakumari, J.G.C.Hamilton and Sarita Nethula. Synthesis of

9-Methylgermacrene from Germacrone, an active analogue of (S)-9-

Methylgermacrene-B sex pheromone of Phlebotomine sandfly,

Lutzoymia longipalpis from Lapinha, Brazil in IUPAC

International Conference 2004, Delhi.

Patents

. Biodegradable Polymer coverings for Breast Implants. (US Patent

Application # 2008/0241212). A. Moses, S. Pulapura, Q. Ge,

Sarita Nethula, I. Shatova, A. Rajaram.

. Dihydroxybenzoate polymers and uses thereof. (US Patent

Application # US2008/062582). A. Moses, S. Pulapura, Q. Ge,

Sarita Nethula, A. Rajaram.

Publications

. J.Chem.Soc.,Perkin Trans I, 2001, 1939-1941

Ultrasound-accelerated synthesis of 3,4-dihydropyrimidin-2(1H)-

ones with ceric ammonium nitrate J.S.Yadav, B.V.S. Reddy,

K.Bhaskar Reddy, A.R.Prasad and Sarita Nethula

. Synthesis 2001, 15, 2277-2280

ZrCl4 catalysed efficient synthesis of (-Amino phosphonates

J.S.Yadav, B.V.S. Reddy, K.Bhaskar Reddy, A.R.Prasad and Sarita

Nethula

. Synthesis 2002, 8, 1061-1064

Indium Tribromide catalysed aminolysis of Aziridines: An

efficient synthesis of vicinal-diamines J.S.Yadav, B.V.S. Reddy,

K.Vishweshwar Rao, A.R.Prasad and Sarita Nethula

. Angew.Chem. 2003, 115, 5356-5359

Indium bromide catalysed cyclisation of glycols with aryl

amines

J.S.Yadav, B.V.S. Reddy, K.Vishweshwar Rao, Kiran, A.C.Kunwar,

Jayaprakash, B.Jagannath, A.R.Prasad and Sarita Nethula

. Tetrahedron 59-200*-****-****

Room temperature ionic liquids promoted three-component

coupling reactions: a facile synthesis of cis-isoquinolic acids

J.S.Yadav, B.V.S. Reddy, A.R.Prasad and Sarita Nethula

. Tetrahedron Letters 2004, 6505-6508

First example of molecular iodine-catalyzed allylation and

alkynylation of cyclic allylic acetates

J.S.Yadav, B.V.S. Reddy, K.Vishweshwar Rao, P.Purushothama Rao,

A.R.Prasad, D.Gunasekhar and Sarita Nethula

References: Available upon request.

Contact this candidate