Medical Device Project

Summary

Two years of experience in patent preparation, prosecution and FTO opinion

work in a boutique IP law firm. USPTO Registration Exam passed. Ph.D. in

Cell Biology with fourteen years of research experience. Applies

perseverance and innovative thinking. Strong team player.

Legal Experience

Lahive & Cockfield, LLP (Boston, MA)

Technical Specialist (USPTO recognized)

January 2008 - March 2010

. Preparation and prosecution of life science patent applications in

foreign and domestic jurisdictions

. Assisted in freedom-to-operate analysis, Intellectual Property portfolio

management and strategy development, patentability/infringement opinion

work, and legal writing

. Practiced in biotechnology, chemistry, medical device and pharmaceutical

areas, such as antibodies, chemical compounds, gene therapy,

transgenics, cancer diagnostics and therapeutics, vaccines, discovery

genetics, and RNA interference

. Mastery of legal and scientific databases (Delphion, GenomeQuest, patent

databases of USPTO, i.e., PAIR, and foreign patent offices, PubMed,

etc.)

. Assisted in patent prosecution and portfolio management for a billion-

dollar antibody drug

. Passed the USPTO Registration Exam in September 2009

Education

Suffolk University Law School (Boston, MA)

J.D. candidate for Evening Division

Expected 2014

Harvard Medical School (Boston, MA)

Ph.D., Cell and Developmental Biology

2008

. Dissertation work in Dr. Junying Yuan's laboratory focusing on the role

of cellular protein modification and degradation in apoptosis and

tumorigenesis

. Research areas including molecular biology, cell biology, biochemistry,

immunology, oncology, virology, etc.

. Identified an oncogenic pathway and the anti-cancer mechanism of a small-

molecule compound (result published in Molecular Cell, specially

commented in Developmental cell)

. Fu Fellowship

Fudan University (Shanghai, China)

M.S., Microbiology

2000

. Three years of research work in a European Union collaborative project

and a Chinese High-Tech (863) Project, both focusing on characterization

of the coat protein of a newly identified plant virus

. Research areas including molecular biology, microbiology, biochemistry,

immunology, etc.

. Three scientific publications in peer-reviewed international academic

journals

. 2001 Science and Technology Progress Prize of Zhejiang Province, China

. Ho Yiwan Scholarship

B.S., Microbiology

1997

. Graduate School Admission Tests exempted for excellent GPA record

. Renmin Scholarship

Societies

. Boston Area Technology Specialists (BATS)

. GSAS Harvard Biotechnology Club

. Biotech & Pharma Professionals Network

Activities

MIT Sloan School (Cambridge, MA)

Member of Innovation Team (i-team)

2006

. Explored commercialization possibilities for a medical device invention

with a provisional patent application

. Collaborated with scientists, MIT technology licensing officers, venture

capitalists, business consultants, attorneys and biotech/pharma

representatives

. Project work won 2007 MIT Deshpande Center Research Grant

Seeding Labs (Boston, MA)

Board Member and Coordinator

2006 - 2008

. Board member of this start-up non-profit organization as a spin-off from

a Harvard student group

. Coordinated donors and volunteers for used laboratory equipment

donation, collection and shipment to support scientists starting their

academic careers in developing countries

Publications

IP-related publications:

Xu, L. and DeConti, G.A. Jr. (2010). Patent Strategy Update: Court

Curtails Extraterritorial Scope of Method Patents. Online publication at

http://www.lahive.com/news_publications/item.html?id=526

Scientific publications:

Xu, L.*, Zhu, J.*, Hu, X., Zhu, H., Kim, H.T., LaBaer, J., Goldberg, A.L.,

and Yuan J.Y. (2007). c-IAP1 Cooperates with Myc by Acting as a Ubiquitin

Ligase for Mad1. Molecular Cell 28, 914-922

(For a special commentary of this work, see Wright, C.W. and Ducket, C.S.

(2008). New Insights into the Function of IAP Proteins: Modulation of the

MYC/MAX/MAD Network. Developmental Cell 14, 3-4)

Xu, L., Chen, J.P., Ye, R., Zhao, X,Y., and Yu, S.Q. (2002). Cloning and

Expression of the Chinese Wheat Mosaic Virus RNA2 Coat Protein and Read-

through and 19 kd Cysteine-rich Domain and Localization of These Proteins.

Chinese Science Bulletin (Chinese Version) 47(6), 439-443

Ye, R., Xu, L., Gao, Z.Z., Yang, J.P., Chen, J.P., Adams M.J., and Yu, S.Q.

(2000). Use of Monoclonal Antibodies for the Serological Differentiation

of Wheat and Oat Furoviruses. Journal of Phytopatholgy 148, 256-262

Ye, R., Zheng, T., Xu, L., Lei, J.L., Yu S.Q., and Chen, J.P. (2000).

Coinfection of Wheat Yellow Mosaic Virus and Rod-shaped Virus Related to

Soil-borne Wheat Mosaic Virus on Winter Wheat in Yantai District. Chinese

Journal of Virology 16, 80-82

*: co-first authors

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