BABAK SHAFII PHD

P. O. ****

Winter Park

FL ****3

PH (407) 719-

4572

EMAIL:

BABAKSHAFII@YAH

OO.COM

OBJECTIVE

Synthetic Medicinal, Organic, Organometallic Chemist, seeking

employment that would utilize my experience and background.

AREAS OF EXPERIENCE

Experienced in Medicinal, organic, organometallic and wet chemistry,

especially in pathway design (and/or improvement) of multistep

synthesis schemes, and characterization of new compounds.

Well versed in instrumental techniques such as UV, IR, NMR, GC, HPLC

as well as photochemical and electrochemical methods.

Specialized research experience in oxygen-, moisture-, light

sensitive material.

Familiar with various laboratory and personal software.

WORK EXPERIENCE

5/94- 5/95 Research Associate, University of Alabama in Birmingham,

Cancer Research

Research Associate University of Alabama in Birmingham-

Developed metal chelating agents such as technetium, copper

and cobalt and their subsequent conjugation to antibodies.

These conjugates were used to deliver radioactive metals to

cancerous tumors.

7/92- 7/93 Senior Research Scientist, Cancer Therapy and Research

Center- Institute for Drug Development, Cancer research.

Senior Research Scientist, Institute for drug development

(Cancer Therapy and Research Center)-Developed drugs for cancer

treatment.

In charge of developing a patent for a two step synthesis

of Tamoxifen and its analogs as well as other triphenyl

ethylene compounds of interest in cancer research.

8/91- 7/92 Research Associate, Argonne National Laboratory, Nuclear

Medicine Group, Cancer Research.

Postdoctoral fellow, University of Chicago Medical School

(Ben May Institute)/Research fellow, Argonne National

Laboratory-Cancer Research.

8/89- 7/92 Post Doctoral Fellow, joint appointment: University of

Chicago medical school (Ben May Institute) and Argonne

National Laboratory, Cancer Research.

Postdoctoral fellow, University of Chicago Medical School

(Ben May Institute)/Research fellow, Argonne National

Laboratory-Cancer Research.

As the chemist on research team, I designed new processes

to improve the published methods for the synthesis of

triphenylethylenes which are of interest in cancer

treatment and tomography. Also devised a new and efficient

procedure specially suited for radiohalogenation of organic

compounds in which yield and specific activity were

optimized, approaching the theoretical limits. Also

introduced new metal ligand substitutes to alter steric

bulk and electropositivity in order to facilitate the

radiolabeling step, while reducing the toxicity of

precursors.

6/88- 5/89 Post Doctoral Fellow, State University of New York-

Binghamton, Synthesis of novel Organometallic compounds

(with JJ Eisch).

1/85- 5/88 Research Assistant, SUNY- Binghamton, Synthesis of novel

Organoboron compounds (with JJ Eisch).

Doctoral candidate, State University of New York-Binghamton-

Organometallic Chemistry (Mentor J.J. Eisch).

Succeeded in synthesizing and isolating a class of

organometallic compounds, namely borirenes, in crystalline

form. Through these efforts, the details of borirene

structure, such as bond lengths and bond angles were

determined for the first time. We demonstrated a facile

synthesis of this class of compounds through published

papers. We further established the predicted adjustments in

theoretical calculations. The above task had been pursued

unsuccessfully by numerous investigators in the preceding

quarter century, as reflected in literature.

9/83- 1/85 Teaching Assistant, SUNY- Binghamton, General Chemistry.

1/82- 1/83 Research Assistant, Organic Chemistry, Georgetown

University, Organic Synthesis and Electrochemistry (with V.

Horak).

Master's Candidate, Georgetown University-Organic

Chemistry. Synthesized and carried out electrochemical

studies of pyridinum hydroquinone chloride and its analogs.

Due to their specific range in oxidation potential and

acidity, these types of compounds were to be employed in

the production of electrodes which are suited for medical

and other applications.

1/81- 1/82 Teaching Assistant, Georgetown University, Organic

Chemistry.

PERSONAL

Citizen Of The United States

References and List of Publications available upon request.

EDUCATION AND TRAINING

Ph.D. in organometallic chemistry, 1988, State University of New

York, Binghamton.

Dissertation Title: "Synthesis of borirenes via the photochemical

rearrangement of ethynylboranes."

M.S. in Organic Chemistry, 1983, Georgetown University. Thesis title:

"Electrochemical study of pyridinium hydroquinone chloride and similar

compounds."

B.S. degree, 1981, University of Southern Colorado.

State of California Department of Public Health Clinical Chemist

Trainee License # TRL2698

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