Manager Plant

RAAJ KUMAR, Ph.D.

**** ****** ***** **** 573-***-**** (Home)

Mexico, MO 65265 573-***-**** (Work)

E-mail:

************@*******.***

PROFESSIONAL SUMMARY

Over 20 years of accomplishment in management and leadership roles in

process development, process optimization, and site management, including

profit/loss responsibilities in the area of active pharmaceutical

ingredient manufacturing.

EXPERIENCE

Teva Pharmaceuticals, Inc., Mexico, MO, USA 1998-present

Plant Manager, Active Pharmaceutical Ingredient Division

2006-present

. Directed and coordinated all activities involved in the operation of

the manufacturing facility

. Provided leadership and direction to 90+ associates through individual

and group interactions and communications

. Improved productivity by 20-25% by optimizing processes and increasing

efficiencies all around. This has resulted in overall profitability of

the plant.

. Controlled and maintained budgets for raw material purchases,

salaries, and capital expenditures; responsible for budget of $60-65

million annually

Scientific Director, R&D; QA and QC; Project, Maintenance and Engineering

1998-2006

. Developed manufacturing processes for semi-synthetic cephalosporin and

penicillin antibiotics, such as Cefuroxime axetil, Cefadroxyl Mono and

Hemihydrate, Cefdinir, Cefprozil, Cefaclor, and Amoxicillin Sodium,

all of which were new to the facility

. Scaled-up and validated new processes in production

. Coordinated the technology transfer of API's and advanced chemical

intermediates

. Contributed towards a successful FDA inspection in 2005

. Implemented many projects economically

. Supervised a staff of 35 employees

Consolidated Pharmaceuticals, Inc. Baltimore, MD, USA 1997-

1998

Manager of Production, SSP Plant

. Optimized processes for Ampicillin and Amoxicillin antibiotics

. Managed plant operations, including production planning and scheduling

. Supervised a staff of 20 employees

Max-Gist Brocades (the Netherlands), Chandigarh (India)

1989-1997

Max India was one of the first companies to start production of ?-lactam

antibiotics in India

General Manager R&D

1996-1997

. Managed all semi-synthetic Penicillins manufacturing plants having 85-

90 employees and with a budget of $50-55 million

. Implemented numerous process and crystallization improvements,

resulting in improved quality, consistency, and yields

. Optimized the Amoxicillin process to a level that it became highly

competitive worldwide, both qualitatively and quantitatively

Controller R&D (Chemical)

1995-1996

. Managed the technical development for the commercial-scale

manufacturing of Cefotaxime and Ceftriaxone

Senior Manager R&D (Chemical)

1993-1995

. Directed process research and development of a cost-effective,

commercially successful process for 7-Aminocephalosporanic Acid (7-

ACA), the major raw material for third and fourth generation

cephalosporin-?-lactam antibiotics

. Provided customer support for customers purchasing 7-ACA

. Prepared scientific papers and reports

Manager R &D (Chemical)

1991-1993

. Optimized processes for Cephalexin, Cefadroxil, Cephradine, for

commercial production

. Reduced production costs by developing recovery processes for key

reagents and solvents

. Developed cost-effective processes for the anticonvulsant,

Carbamazepine; the antihistamine, Terfanadine; and the macrolide

antibiotic, Azithromycin

Deputy Manager R& D (Chemical)

1989-1991

. Developed and optimized processes for semi-synthetic penicillin

antibiotics Ampicillin, Amoxicillin, Cloxacillin, and Flucloxacillin

. Improved yields by 10-20% over existing norms thereby reducing costs

Esscee Biotech India, Pvt. Ltd., Lucknow, India

1988-1989

Research Manager

. Established a 100% export unit in collaboration with Chemgenes Corp.,

USA to manufacture phospharamidites-the chemical intermediates for

automated gene synthesis

. Carried out research and directed efforts of a team of scientists

involved in the development of shorter and economic routes to various

DNA and RNA intermediates

Pest Control India Ltd., Bangalore, India

1986-1988

Manager, Natural Products

. Planned and directed the efforts of a team of scientists involved in

the synthesis of various pheromones

. Set up the facility

Union Carbide India Ltd., Bhopal, India

1983-1986

Research Chemist

. Synthesized over one hundred novel benzoylureas (organophosphorus

compounds) as potential insecticides

. Characterized many novel compounds by modern physical methods and

tested their efficacy

. Obtained patent 4,473,404 for two new potential insecticides

ACCOMPLISHMENTS AND SKILLS

Demonstrated ability to turn around manufacturing capabilities,

efficiencies, and profits

Global experience in plant start-up and trouble shooting in US, EU, and

Asia

Skilled in developing shorter and economic routes to target molecules

Experienced international traveler, including Europe and Asia, for

troubleshooting and start-up of chemical processes

Proven ability to work in a team environment and lead project teams

Possess leadership, communication, and management skills

Excellent oral and written communication skills

Strong knowledge of cGMP regulations

EDUCATION

Ph.D. Organic Chemistry : Indian Institute of Technology, Kanpur, India

M.S. Chemistry: Delhi University, Delhi, India.

B.S. (with Honors) in Chemistry: Delhi University, Delhi, India.

PUBLICATIONS AND PATENTS

1. Available upon request"A Practical, Convenient and Highly

Stereospecific Synthesis of 1-Acetoxy (E) 9,11-Dodecadiene, the insect

sex pheromone of Bollworm Moth", Ranganathan,S., Kumar, R., and

Maniktala V., Synthetic Communications,12, 921 (1982).

2. "Synthesis of Insect Sex Pheromone of Achroia Grisella Via the Novel

Synthon 1-Tetrahydropyranyloxydodec-11-yne", Ranganathan S., Maniktala

V., and Kumar R., Synthetic Communications,12, 959 (1982).

3. "On the mechanism and Synthetic Applications of Thermal and Alkaline

Degradation of C-18 Castor Oil", Ranganathan S., Kumar R., and

Maniktala V., Tetrahedron, 40, 1167 (1984).

4. "Metamorphosis of Castor Oil to Insect Sex Pheromones and Useful

Synthons", Ranganathan S., Maniktala V., Kumar R. and Singh G.P.,

Indian Journal of Chemistry, 23b, 1197 (1984).

5. "Pesticidal Benzoylureidoaryl Phosphate Compounds and Process for

Preparation", US patent 4,734,404 (March 29, 1988).

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