Technician Manager

Trent J. Pearson

***** ****** ****** #* ( North Hollywood, Ca. 91601 ( 818-***-**** (

abke9a@r.postjobfree.com

In Vivo Pharmacology

Providing today's Pharmacology with 15 years of hands on expertise of

animal use in modern drug discovery.

Relevant Skills

> Recruit, Train, and Supervise (Project / Technical

Coordinator), group members for investigational

studies pertaining to in vivo research

> Protocol Management for animal facilities, and

research laboratories. Write reports regarding

scientific data using Microsoft Office and various

scientific software programs (Prism, Lab Cat, Onco

Lims). Familiar with USDA, FDA, DEA, and OSHA

> All aspects of animal research / veterinary practice

and procedures; behavior, handling, restraint,

administrate medication, specimen collection (CSF,

tissue, blood, urine, bile, feces, etc.), various

surgeries (i.e., catheterization), euthanasia and

necropsies

> All aspects of general laboratory and in house

veterinary equipment, surgical instruments, including

recent training / experience with Isis Imagining

Systems

> Exposed to in vitro techniques: various tissue

extractions, cell culture, RIA, ELISA, Western Blot

Work Experience

03/08 to 08/08 Pfizer, ManPower Contractor

Scientist

Cancer Biology. Execute in vivo (Efficacy TGI, PD, TK, and

PK/ADME), in drug discovery regarding Oncology.

Provide multiple teams in Pfizer a broad range of in vivo

expertise.

. Impact Award given for Dedication, Hard Work, and

Contributions in Cancer Biology

06/06 to 10/07 Takeda San Diego

Sr. Research Associate

Developmental Pharmacology. Design, lead, and execute in

vivo (efficacy, OGTT, MTD, Exploratory Tox, Behavioral, and

PK/ADME), in drug discovery regarding Metabolic Diseases

and Oncology. Work done in an off site vivarium.

. Designed and implemented animal IV infusion technical

support.

02/04 to 06/06 TorreyPines Therapeutics Inc., formerly

Neurogenetics Inc.

Research Associate / Vivarium Supervisor

Pharmacology. Design, lead, and execute in vivo (efficacy,

tox, brain penetration, behavioral, and PK/ADME), in drug

discovery programs regarding Alzheimer's disease. Supervise

vivarium staff and operations.

. Designed and implemented a unique filing system for assay

data and samples.

12/03 to 04/04 Metabasis

Consultant

Pharmacology. The execution of in vivo (diet, behavioral),

in drug discovery programs regarding

metabolic diseases. Worked as an on-call basis.

. Brought new techniques and ideas in order to complete daily

tasks more efficiently and effectively.

11/01 to 11/03 MitoKor

Sr. Research Associate

Pharmacology. Design, lead, and execute in vivo / ex vivo

assays (Feeding, Behavioral, PK/ADME), survival surgeries,

and necropsies in drug discovery programs regarding

Diabetes, Obesity, and O.A.

. Developed Sx. / tactical techniques for successful, stress-

free OGTT/PK, kept expense minimal.

05/01 to 11/01 Tanabe Research Laboratories

Vivarium Manager / Research Associate

Responsible for the on site vivarium and its operations,

meeting the requirements for state and federal guidelines;

served as a member for the facilities IACUC. Assisted in

the planning and execution of all in vivo assays, PK/ADME,

surgeries, and necropsies in various study programs.

. Identified and corrected violations preventing termination

of vivarium utilization.

Work Experience (Continued)

01/01 to 05/01 Sierra Biomedical CRL

Research Technician

Technical Team Member responsible for conducting GLP

research studies. Technical skills include use of

anesthesia, tissue collection, weighing, and recording.

Assisted with regular and zinc formalin necropsies, and

euthanasia. Performed PK/ADME studies, sample collection,

blood processing, data collection verification, dosing and

dose verification, and clinical observation documentation

of various animal models.

. Brought new techniques and ideas in order to complete

daily tasks more efficiently, while working with

colleagues to incorporate these techniques and skills

to fit GLP guidelines.

11/98 to 12/00 Kelly Scientific (Long-Term Temp)

Trega Biosciences Inc.: Research Associate

In the Pharmacology group, assisted in the designing and

execution of all in vivo assays (Feeding, Behavioral,

PK/ADME) and necropsies in several drug discovery programs.

Oversaw and reported all animal health observation and

treatment for off-site veterinarian.

The Salk Institute: Vivarium Technician

Worked in the Animal Research Division, performing all aspects of

professional husbandry of laboratory TG Mice in a clean

(sterile) vivarium.

PharMingen/Becton Dickinson: Laboratory Technician

Worked in tissue culture, performing concentration and

clarification of grown cells in the production of

antibodies for sales under GMP guidelines.

. Nominated Kelly Scientifics' most dependable employee

in the San Diego Region, for being knowledgeable,

thorough, organized, and a vital asset to each

company worked at.

06/1998 to 01/1999 VCA Emergency Animal Hospital & Referral Center,

Hotel Circle

San Diego, California

Veterinary Nurse

Basic Emergency

Care: medical and surgical procedures on domestic,

exotic, and wild animals.

. Taught colleagues the value of compassion in dealing

with pets and their owners.

03/1993 to 07/1997 Zoological Society of San Diego (Center for

Reproduction of Endangered Species)

Endocrinology Division

Research Laboratory Technician - Intern

Participant in the "Bonobo Project" investigating the

relationship between behavior and hormone levels, to

improve reproduction of this endangered species in

captivity.

Comparative Physiology / Ecology Division

Field Research Technician

Conservation of the San Diego Coast Horned Lizard on the

Southwestern Riverside County Multi-Species Reserve.

Capturing, handling, tagging, injecting transponder data

chips, collecting blood and feces, observing foraging

behavior in the endangered San Diego Coast Horned Lizard.

Comparative Physiology

Research Technician / Animal Keeper - Volunteer

Participant in several ecological research projects,

including Komodo dragon diet experiment, research on the

effects of social environments on reproduction in Savanna

Monitor lizards, communication and social dominance in

Fijian banded iguanas, and an experimental "head start"

release program for Cuban rock iguanas.

Primate Research Pad

Animal Keeper Assistant - Volunteer

Prepared animal food using charts and scales. Provided

keeper with back-up help such as capturing, weekly body

weights, relocating animals, and enclosure maintenance.

Participant in various behavioral studies.

. Instrumental in the termination of illegal importing

of certain iguana species.

Most Recent Publication: Poster / Abstract

A selective ?-secretase inhibitor PF-03084014 demonstrates anti-tumor

activity in Notch-driven cancers

AACR 100th Meeting, Denver CO, 2009

Job Training /Certifications (partial list)

2010- Personal Education: Lab Animal Subscription, and on-line

Research / Articles

2008- Pfizer: Onco-Lims / Biobook Software, and Isis Imaging Systems,

LARC / IACUC Training

2007- Takeda: LABCAT Software, and IACUC Training

2004- TorreyPines Therapeutics Inc.: OSHA (fire), Working with the

IACUC

2001- Sierria Biomedical: IACUC, Working with Anaesthesia for Animals,

Toxicology Seminar,

Principals of Surgery and

Sterile Technique, and more...

1999- Salk Institue: AALAS, and IACUC (Training)

1998- Trega BioSciences: Aspects of Study Design and Execution

(PK/ADMA, OGTT, and Etc.)

1993- San Diego Zoo: Behavioral Observation / Scoring in Animals

Education:

10/1998 to 12/1999 Platt College ? San Diego, Ca

A fifteen month commercial and computer graphic design

program

08/1996 to 06/1997 San Diego City College District ? San Diego, Ca.

Prerequisite, general education

Contact this candidate