Rithika Ganni
**** *** ******* #**** *****: 804-***-****
Fairfax, VA 22031.
Email: *******.*****@*****.***
Objective: To obtain a Position in the field of Bioinformatics that will
utilize my strong Programming, Communication, and Management skills.
Education:
Masters in Bioinformatics and Computational biology,
George Mason University (2008 - 2010) GPA - 3. 86
Bachelor of Science, Biotechnology
Jawaharlal Nehru Technological University (2004 - 2008) GPA -
3.8
Work Experience:
1. PTAP, Mason Enterprise Center, GMU (January '2009 - present):
. Database management of all the clients and their companies using SQL
and Python.
. Maintaining the website using PERL CGI module and HTML.
. Organizing business seminars and enacting computer technical
support.
. Maintaining accounts monthly and survey reports every three months.
2. Print Services, GMU.(September '2008 - January '2009):
. Assist the patrons with the Printers, scanners and copy machines.
. Perform or supervise the print jobs.
. Maintain the records for all the print jobs done in the university.
3. Jawaharlal Nehru Technological University, India ( June'2008 - August'
2008 ):
. Teaching Assistant for the course "basics of database management
systems".
. Helped the students with basics of DBMS.
. Conduct and grade the mid-term test for students.
4. Help Desk, JNTU, India ( May' 2008 - July' 2008):
. Assist in making appointments with faculty and administrative
persons.
. Set up schedules for major events and classes in the department.
. Manage student accounts for grades and admissions.
5. Reddy Labs, India (November '2007- April'2008)
Worked in an Internship position as Research Assistant which includes
dealing with all the major instruments for Quality control in
Pharmaceutical industry.
6. Jawaharlal Nehru Technological University ( Feb' 2006 - Dec' 2007)
. Research Assistant in Molecular Biology laboratory.
. Also help the instructor with buffer and media preparation.
. Produce SDS PAGE electrophoresis gels, Separate DNA from blood
samples.
Skill Set:
Programming : Perl, Python, SQL, bash scripting, awk, sed, C#.NET,
ASP.NET, C, SAS
Platforms : UNIX, Windows XP/Vista/7
Tools / Packages : MS office, Dreamweaver 8, Flash
Database Servers : MYSQL, SQL Server 2005, Oracle
Biological Databases : PDB, Ensembl, UniProt, Prosite, SCOP,
GenBank, Entrez, PubMed.
Web Technology : HTML, JavaScript, XML, AJAX, PERL-CGI.
Lab Techniques : Electrophoresis, Media preparation, DNA isolation and
Amplification, Western Blot and Elisa, Immuno-diffusion,
various
Screening and culturing techniques, Fermentation,
Microarrays.
Bioinformatics tools : BLAST, PsiBlast, WEKA, ClustalW, PSiPred, Jpred,
3D-PSSM, ExPASy
Proteomics tools.
Other : Knowledge of HLA genes, adenovirus genome, primer design,
Microarray analysis etc...
Projects:
. Web interfaces for Bioinformatics Applications:
> Comparing Two MSA Algorithms:
A web interface is developed where two Multiple Sequence Alignment
Algorithms are implemented and compared using PERL and PYTHON. The Greedy
and Non-Greedy Algorithms for Multiple Sequence Alignment are compared.
GeneDB: A HUMAN GENE DATABASE:
A web interface for a Human Gene Database is developed using SQL and
PERL. Any human gene can be retrieved by giving a keyword or and part of
the gene accession number or gene name. The results are links directing
to the Genbank database.
> Protein Structure Analysis Tool:
An interactive web based Protein Structure Analysis tool was developed.
Here the protein structure is predicted using two different algorithms
from the primary sequence of the protein. Various databases like
UNIPROTKB, PDB and bioinformatics tools like PAR 3D, "Conserved domains"
in NCBI, verify 3D, PHYRE, Anolea and Gromos are used for this project.
The URL is http://binf.gmu.edu/~rganni/PSA2.html
> Finding ORF regions in Genomes:
A Web interface for identifying potential coding region in a Genome is
developed. The program works for the circular genomes as well. The code
is implemented in PERL.
. Data Mining Projects:
> Classification of Proteins into Solenoids and Non-Solenoids:
Secondary structure of new protein sequences is predicted for sequence
analysis using Hidden Markov model approach. Using this information,
proteins are classified to Solenoids and Non-Solenoids using the data
mining tool WEKA. The codes required are implemented in the scripting
language PERL.
> Functional classification of Proteins using LDA:
The Enzyme Classification of the proteins is done using the features
obtained from the generative LDA method. These are used in a
discriminative framework for protein functional classification. The codes
are in C, C++ and PERL.
> Prediction of Secondary Structure:
The Secondary structures of a set of protein sequences are predicted
using Markov Chains approach. A separate set of proteins with known
secondary structures is used as the training data to train the model.
. Microarray Data Analysis using Python:
The Microarray data of six samples is studied and the outliers are
identified. For this the data is first plotted in M vs. A graph. Then the
multi-file normalization was performed to remove the bias. Finally the
outliers are found. This project is implemented in Python.
. C#.NET and ASP.NET projects:
> Developed a web page for Shipment schedule:
C# ASP.NET Web program is developed to display shipping times for a
selected customer, employee, and shipping company from a preexisting
database.
> Developed a Windows program for time sheets of employees:
A C# Windows program to display time card data for a selected employee
from a list of employees is developed.
> Implemented the working of an elevator:
A C# console application is developed to implement the working of an
elevator when the highest and least floors and maximum capacity of the
lift are given.
Strengths:
. Ability to follow detailed operating procedures and protocols with
minimal supervision, work in diverse ethnic groups and adjust in a
team.
. Experience with lab instrument and equipment maintenance
. Excellent oral and written communication skills
. Dedicated, Determined and Duty minded in pursue of goals and
objectives.
References:
. Dr. Huzefa Rangwala,
Assistant Professor, GMU,
Email: ********@**.***.***
Phone: 703-***-****
. James Regan,
Director, Virginia PTAP, GMU,
Email: ******@***.***
Phone: 703-***-****
. Mary McGuire,
Operation Manager, PTAP, GMU,
Email: ********@***.***
Phone: 703-***-****