J oseph Aprile

**** **** *** **

Seattle, WA ****6

206-***-**** abjwhv@r.postjobfree.com

http://www.linkedin.com/in/japrile

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SUMMARY

A rich and varied experience as a writer with numerous published works in the

literary and technical fields. These accomplishments demonstrate a passion for

writing and a potent and lively imagination.

PROFESSIONAL EXPERIENCE

SEATTLE INSTITUTE OF PEACE STUDIES (SIPS) 2007-Present

President and Co-founder

Mission of SIPS is educational – to introduce peaceful alternatives to conflict resolution.

FRED HUTCHINSON CANCER RESEARCH CENTER (FHCRC) 1980-2009

Systems Administrator 1994-2009

System and Network Administrator for the Public Health Sciences Division (PHS). This

work entailed technical support in both networked (Windows) and standalone systems,

network administration, user account, file, print and asset management, and

troubleshooting both hardware and software problems.

• Setup a Center-wide software application training program that involved

the creation of course materials and teaching a plethora of software

applications to over 1000 employees

• Created and maintained an Intranet website for the PHS IT Department.

• Created Web-based forms to streamline the setup of employee user

accounts.

• Created and managed SQL databases for the PHS IT Department

• Creation of software documentation that covered many diverse platforms

• Involved in the administration of the Y2K transition for the entire FHCRC

campus

• Migrated various PHS studies from standalone to fully networked systems.

• Administered and maintained Windows-based Servers in support of the

PHS Division

• Part of the Administrative team that transitioned server hardware to virtual

systems.

Research Investigator 1980-1994

Involved in independent research in basic immunology. Created, Managed and

supervised research laboratories in the Transplantation Biology Program in the Clinical

Division. Supervised both staff and visiting scientists in regards to specialized

techniques and research methodologies. Original work published in peer-reviewed

journals and presented at both national and international meetings.

NORTHWEST INSTITUTE OF ACUPUNCTURE

AND ORIENTAL MEDICINE 1983 - 1989

Associate Professor of Biochemistry in the Division of Western Sciences at Northwest

Institute of Acupuncture and Oriental Medicine, Seattle, WA.

SEATTLE CENTRAL, TACOMA and FORT STEILACOOM

COMMUITY COLLEGES 1978-1982

Instructor of Introductory Chemistry and Biology and Organic Chemistry

BASTYR UINVERISTY 1978-1981

Instructor of Biochemistry and Interim Academic Dean

PACIFIC LUTHERAN UNIVERSITY 1978-1980

Instructor of Chemistry

UNIVERSITY OF COLORADO AT BOULDER 1974-1978

Research Technologist in the laboratories of Dr. Noboru Sueoka at the University of

Colorado at Boulder. This work entailed research in the area of the biochemistry of

neuronal proteins.

THE CHELSEA ALTERNATIVE SCHOOL 1970-1973

Cofounder and Science Teacher – Physical and Biological Sciences

EDUCATION:

MS Biochemistry, North Carolina State University, Raleigh, NC

BS Biology, Manhattan College, New York, NY

Certificate in Microcomputer Management, Seattle Central Community College, Seattle

Network Systems Engineer (NSE) certification program

AWARDS:

1959 - National Science Foundation Award

1962 - New York State Regents College Scholarship

1962 - Manhattan College Scholarship

Published Works

Awakening from a Distant Dream:

This is a story about Laura. Laura was born with a sensitive spirit. As an adolescent, she is

plagued by feelings of uncertainty and confusion about her relationship with her family and

friends, but, most importantly, her personal identity and place in the social order of things. As

events unfold, circumstances propel her into situations where she is forced to make some

momentous decisions that will help her eventually come to terms with her own nature. Laura

ultimately discovers her true calling in life and the artist she was destined to be. This singular

existence illustrates the challenges that shape the depth and unique character of the self.

The Surprising Latitude of Fate:

The Surprising Latitude of Fate is a novel that follows the life of an Italian immigrant (Carmelo

Visconti) as he attempts to navigate his way through the intricacies of the American culture. He

is catapulted from village life in a small town on the Adriatic to the frenetic pace and lifestyle that

comes with living in New York. His innate sense of adventure together with his burgeoning

loneliness leads him on a path that he would come to regret. Carmelo is exposed to the darker

elements of his psyche that he was previously unaware of, especially his more violent nature.

The inevitable consequences of his behavior bring him to a precipice that could result in his

destruction. It is essentially the story of personal redemption.

At the Fringes of Experience:

This collection of novellas deals with the larger issues of the human condition. Bronx Memories

represents the author’s own personal journey as a young boy. Nathaniel Hastings is a kind of

modern day odyssey, in which the protagonist navigates through life from very bizarre

beginnings. The stories, Bradley Stimpson and Marie, The Strange Diaries of Jeremy Flood and

Benjamin’s Magic Bullet take place in some future time and explore various aspects of

contemporary human society. Lastly, No Time for Retribution is a work that examines the modern

world as seen through the eyes of a person dealing with madness.

America and the Mythology of Greatness:

This well researched book examines the myths about America and its moral position in the

world. The myths enumerated include the myth of equal justice and the myth of America as the

so-called “world policeman.” The premise of this work is that a belief in these myths distorts the

truth and impedes real social progress. Alternatives are suggested that are more in keeping with a

truly free and democratic society.

Impaled on Time’s Illustrious Arrow:

This collection of poetry (over 150 poems) covers a wide range of thoughts, reflections and

experience. Poetry to me is a succinct medium through which the many layers, and often elusive,

textures of emotions can best be expressed.

The Illusive Quality of Existence:

This collection of poetry (some 200 poems) is a collection of more recent work and includes what

the author refers to as picture poems, i.e. poems that include color images from original art and

photographs.

The Human Equation:

This collection of short stories (335 pages) encompasses a wide range of genres including literary,

fantasy, science fiction, mystery and humor. This work is available at Lulu.com .

A Particular Passing Through Time:

This novel begins with Anthony on his death bed and follows him through the odyssey of his life

through the wealth of his memories. This work is available at Lulu.com .

Scientific Addendum

Joseph A Aprile, Margaret Russo, Margaret Pepe, Thomas P Loughran Jr., Activation Signals

Leading to Proliferation of Normal and Leukemic CD3+ Large Granular Lymphocytes,, Blood,

September, 1991, 78, 1282-1285

Thomas P Loughran Jr, Gordon Starkebaum, Joseph A Aprile, Rearrangement and Expression of

T-Cell Receptor Genes in Large Granular Lymphocyte Leukemia,, Blood, March, 1988, 3, 822-

824

Joseph Aprile, Lisa Gerhard-Miller, H Joachim Deeg, Cluster Formation of Canine Dendritic Cells

and Lymphocytes is Calcium Dependent and not Inhibited by Cyclosporine,, Experimental

Hematology, January, 1990, 18 ((1), 32-36

H Joachim Deeg, Joseph Aprile, F Schuening, Robert Raff, Ranier Storb, Functional Dendritic

Cells are Required for Transfusion-Induced Sensitization in Canine Marrow G raft Recipients,,

Blood, April, 1988, 71(4), 1138-40

H Joachim Deeg, Joseph Aprile, E Severns, J Schmidt, Ranier Storb, Phenotypic and Functional

Alterations of Recipient Lymphocytes after Transfusion of UV-Irradiated and Normal Blood,,

Transplantation Proceedings, February, 1987, 19, 2709-14

H Joachim Deeg, Joseph Aprile, TC Graham, Fred Appelbaum, Ranier Storb, Ultraviolet

irradiation of Blood Prevents Transfusion-Induced Sensitization and Marrow Graft Rejection in

Dogs,, Blood, February, 1986, 67 (2), 537-39

Joseph Aprile, H Joachim Deeg, Ultraviolet Irradiation of Canine Dendritic Cells Prevents

Mitogen-Induced Cluster Formation and Lymphocyte Proliferation,, Transplantation, December,

1986, 42 (6), 653-60

MS Tsoi, Joseph Aprile, Sondra Goehle, Ranier Storb, Enrichment (and Depletion) of Human

Suppressor Cells with Monoclonal Antibodies and Immunoglobulin-Coated Plates,, Journal of

Immunological Methods, September, 1982, 53 (3), 293-305

H Joachim Deeg, WC Ladiges, Joseph Aprile, F Schuening, Robert F Raff, Ranier Storb,

Monoclonal Antibodies to Canine Differentiation Antigens,, Methods and Findings in

Experimental and Clinical Pharmacology, November, 1987, 9 (11), 749-53

JC Wulff, N Durkopp, Joseph Aprile, MS Tsoi, SC Springmeyer, H Joachim Deeg, Ranier Storb,

Two Monoclonal Antibodies (Dly-1 and Dly-6) Directed Against Canine Lymphocytes,,

Experimental Hematology, August, 1982, 10 (7), 609-19

JC Wulff, MS Tsoi, Joseph Aprile, HJ Deeg, N Durkopp, Ranier Storb, Stimulation of Canine

Lymphocyte Subpopulations Separated Nonlytically by Monoclonal Anti-T and Polyclonal Anti-B

cell Antibodies,, Blut, November, 1982, 45 (5), 309-16

TP Loughran Jr., Joseph Aprile, Activation Signals Leading to Proliferation of Normal and

Leukemic CD3+ Large Granular Lymphocytes,, The American Society of Hematology 32nd

Annual Meeting

Thomas P Loughran Jr, Joseph Aprile Francis W Ruscetti, Anti-CD3 Monoclonal Antibody-

Mediated Cytotoxicity Occurs Through an Interleukin-2-Independent Pathway in CD3+ Large

Granular Lymphocytes,, Blood, February, 1990, 75 (4), 935-40

RF Raff, HJ Deeg, TP Loughran, TC Graham, Joseph Aprile, GE Sale, R Storb, Characterization

of Host Cells Mediating Resistance to Marrow Grafts in Dogs Transplanted from Unrelated DLA-

Non Identical Donors,, XI International Congress of the Transplantation Society

HJ Deeg, Joseph Aprile, J Rajantie, FR Appelbaum, R Storb, Recipient Sensitization Pre-Marrow

Transplant by Normal but Not by (UV)-Exposed Blood,, XI International Congress of the

Transplantation Society

Joseph Aprile, HJ Deeg, T Castner, L Miller, R Storb, Impaired Expression of Class-II Antigens on

Canine Dendritic Cells Following Ultraviolet Irradiation,, International Society of Experimental

Hematology,, 1987

Joseph Aprile, H Joachim Deeg, Jan C Wulff, Robert Raff, Purified Canine Monocytes Fail to

Confer Concavalin-A Responsiveness to Accessory-Cell-Depleted Lymphocytes,, Experimental

Hematology,, 1984, 12, 45-51

Masaru Imada, Philiph Hsieh, Noboru Sueoka, Separation of Mammalian Cell Surface Proteins

by a Two-Dimensional Gel Electrophoresis System,, Biochimica et Biophysica Acta,, 1978, 507,

459-469

Joseph Aprile, Robert Horton, Modification of Bovine Carboxypeptidase A with Tryptophan

Reporter Group: 2,5 Dihydoxy Benzyl Sulfonium Bromide,, North Carolina State University

Masters Thesis, August, 1970

Deeg, HJ, Aprile J, Wulff JC, Raff R, Canine Accessory cells: Purified monocytes fail to confer

ConA reponsiveness to purified lymphocytes,, XIIth Annual Meeting of the International of

Experimental Hematology, July 10-14, 1983

Deeg HJ, Storb R, Aprile JA, Graham TC, Prevention of Transfusion Induced Sensitization of

Ultraviolet Irradiation of the Transfusion Product,, Experimental Hematology

Aprile JA, Jeeg HJ, Modification of In-Vitro and In-Vivo Function of Canine Blood Leukocytes by

UV Irradiation is Associated with Cell Surface Alterations,, Experimental Hematology,, 1986, 14,

508

Raff RF, Loughran TP Jr, Graham TC, Aprile JA, Sale GE, Storb R, Characterization of Host Cells

Mediating Resistance to Marrow Grafts in Dogs Transplanted from Unrelated DLA-Non Identical

Donors,, Blood,, 1986, 68, 861

Ladiges WC, Deeg HJ, Aprile J, Raff R, Schuening F, Storb R, Differentiation and Function of

Lymphohemopoietic Cells in the Dog,, Comparative Aspects of Differentiation Antigens in the

Lympho-Hemopoietic T,, 1987

Deeg HJ, Aprile J, Severns E, Rejantie J, Green K, Schmidt I, Storb R, Transfusion Induced

Phenotypic and Functional Alterations of Recipient Lymphocytes-Implications for Marrow

Transplantation,, Transplantation Proceedings,, 1986

Raff RF, Loughran TP, Deeg HJ, Aprile JA, Graham TC, Sale GE, Storb R, Role of Radiation

Resistant Large Granular Lymphocytes in the Rejection of Unrelated DLA-Non Identical Marrow

Grafts in Dogs,, Transplantation Proceedings,, 1987, 19, 2718

Deeg HJ, Aprile J, Cereb N, Storb R, Functional Dentritic Cells (DC) are Required for IN-Vivo

Sensitization,, Experimental Hematology,, 1987, 15, 452

Deeg HJ, Ladiges WC, Aprile J, Schuening F, Raff RF, Storb, Monoclonal Antibodies to Canine

Differentiation Antigens.,, Methods and Findings in Exp and Clin Pharmacology,, 1987, 9, 749

Ladiges WC, Deeg HJ, Rajantie J, Severns E, Aprile J, Raff R, Storb R, A Monoclonal Antibody

which Inhibits Accessory Cell Function in the Dog and Recognizes a Human CD-9-Like Antigen,,

FASEB,, 1988

Yoon HJ, Aprile JA, Loughran TP Jr., Interleukin-2 Receptor Monoclonal Antibodies Have No

Effect on anti-CD3 Monoclonal-Mediated Cytotoxicity in CD3+ Leukemic Large Granular

Lymphocytes,, Cellular Immunology

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