WEIRONG ZHANG

**** **** ***** **, **** Worth, TX 76137 817-***-****

abid4q@r.postjobfree.com

STATEMENT Highly motivated and enthusiastic team player with extensive

clinical/research experience and demonstrated skills in

results-oriented project/team management seeks new challenges

in pharmaceutical industry.

EDUCATION Doctor of Philosophy - Physiological Sciences; the University

of Florida, Gainesville, FL; Dec. 2004; Dissertation Title:

"Role of the dorsal periaqueductal gray activation in the

neural control of breathing"; Advisor: Paul W. Davenport,

PhD.

Master's Degree - Medicine; Nanjing University School of Medicine,

Nanjing, China; Jul. 1996.

Bachelor's Degree - Medicine (M.D. equivalent); Nanjing University

School of Medicine, Nanjing, China; Jul. 1994.

Experience The University of North Texas Health Science Center: Fort

Worth, TX

Research Assistant Professor (Jul. 2009 - present):

Department of Integrative Physiology

. Established independent research projects on diabetic

neuropathies and diabetic medicine.

. Received an intramural faculty seed grant (Principle

Investigator, 1/2010-1/2011, total cost: $30,938).

. Course director: Seminar in Current Topics (PSIO 5140; Fall

2009 and Spring 2010).

The University of Texas Health Science Center: San Antonio, TX

Research Instructor (Mar. 2008 - Jun. 2009): Department of

Pharmacology

Postdoctoral Fellow (Jan. 2005 - Feb. 2008): Department of

Pharmacology

. Established independent research projects to study

pathophysiology of sleep apnea.

. Received a Beginning Grant-in-Aid from the American Heart

Association South Central Affiliate as (Principle

Investigator, 7/2008-6/2010, total cost: $140,000).

The University of Florida: Gainesville, FL

Graduate Research Assistant (Jan. 2001 - Dec. 2004): Department of

Physiological Sciences

. Played a leading role in designing and performing human

studies on the function of cerebral cortex in response to

respiratory mechanical events in order to understand

respiratory perceptual deficits in patients with life-

threatening asthma, including recruiting patients and

control healthy subjects, training in HIPPA, IRB and

corresponding policies.

. Led an animal study to investigate the role of stress in

autonomic regulation, including training in IACUC and

corresponding policies.

. Participated in a contract project from Schering-Plough Co.

to test the effect of a cough medicine on the urge-to-cough

in healthy human subjects.

. Graduate Teaching Assistant: Veterinary Gross Anatomy (VEM

5101, Fall 2003); Physiology of Mammals (VME 5244, Fall

2002).

Nanjing Gulou Hospital: Nanjing, China

Attending Physician (Jun. 1999 - Oct. 2000): Department of Geriatrics

Resident Physician (Aug. 1996 - May 1999): Department of Geriatrics

. Clinical practice, including leading a team of resident

physicians as attending physician.

. Supervision of resident physicians and medical students at

the Department of Geriatrics (as Attending Physician),

including clinical teaching, rotation/shift management,

clinical trial coordination, referral coordination.

. Leading role in assisting Principle Investigator in a Phase

III trial of Tea Pigments in cancer patients, additional

responsibility including testing drug effect on several

cancer cell lines in vitro.

Nanjing University School of Medicine: Nanjing, China

Internship (Jul. 1994 - Jun. 1995): Nanjing Gulou Hosptial

Research Assistant (Spring semester 1991)

. Undergraduate science project to test a synthetic tri-

peptide growth factor on wound healing in rats and cell

growth in cultured primary endothelial cells from human

umbilical cord veins with liquid scintillation counting

method.

PROFESSIONAL . Training in HIPPA, IRB, IACUC and corresponding

policies; Extensive knowledge of

SKILLS FDA GLP regulations and ICH/GCP Guidelines; Extensive

experience in project/team management.

. Expertise in research design and data collection and

analysis with SPSS software; Extensive experience in

scientific/business writing, conference presentation,

progress report, and grant application; Proficient with

Microsoft Office.

. Extensive experiences in: electrophysiological recordings

in animals, ECG/EMG/EEG and cardio-respiratory parameter

recordings in humans; psychophysiological evaluation in

humans; cellular/molecular/biochemical techniques (confocal

microscopy, HPLC, PCR, Western blotting, cell culture,

immunohistochemistry, in situ hybridization, etc.).

. Expertise in animal surgeries, including cannulation,

device implantation, microinjection of various compounds

into discrete brain regions, establishing animal models of

hypertension, heart failure, cirrhosis, and stroke.

PUBLICATIONS . Zhang W* and Mifflin SW. Chronic hypertension

enhances pre-synaptic inhibition by baclofen in the nucleus

of the solitary tract. Hypertension, 55: 481-486, 2010.

. Zhang W and Mifflin SW. Plasticity of GABAergic mechanisms

within the nucleus of the solitary tract in hypertension.

Hypertension, 55: 201-206, 2010.

. Zhang W, Hayward LF and Davenport PW. Influence of dorsal

periaqueductal gray activation on respiratory occlusion

reflexes in rats. Autonomic Neuroscience: Basic and

Clinical, 150: 62-69, 2009.

. Zhang W, Carreno FR, Cunningham JT and Mifflin SW. Chronic

sustained hypoxia enhances both evoked EPSCs and

norepinephrine inhibition of glutamatergic afferent inputs

in the nucleus of solitary tract. Journal of Neuroscience,

29: 3093-3102, 2009.

. Zhang W, Carreno FR, Cunningham JT and Mifflin SW. Chronic

sustained and intermittent hypoxia reduce the function of

ATP-sensitive potassium channels in the nucleus of solitary

tract. American Journal of Physiology - Regulatory,

Integrative and Comparative Physiology, 295: R1555-R1562,

2008.

. Zhang W, Hayward LF and Davenport PW. Respiratory responses

elicited by rostral versus caudal dorsal periaqueductal

gray stimulation in rats. Autonomic Neuroscience: Basic and

Clinical, 134: 45-54, 2007.

. Zhang W, Herrera-Rosales M and Mifflin SW. Chronic

hypertension enhances the postsynaptic effect of baclofen

in the nucleus tractus solitarius. Hypertension, 49: 659-

663, 2007.

. Zhang W and Mifflin SW. Modulation of synaptic transmission

to second-order peripheral chemoreceptor neurons in caudal

nucleus tractus solitarius by ?1-adrenoreceptors. Journal

of Pharmacology and Experimental Therapeutics 320: 670-677,

2007.

. Davenport PW, Chan PY, Zhang W and Chou YL. Detection

threshold for inspiratory resistive loads and respiratory-

related evoked potentials. Journal of Applied Physiology

102: 276-285, 2007.

. Zhang W and Davenport PW. Neural control of breathing.

Perspectives on Voice and Voice Disorders 15: 20-24, 2005.

. Zhang W, Hayward LF and Davenport PW. Respiratory muscle

responses elicited by dorsal periaqueductal gray

stimulation in rats. American Journal of Physiology -

Regulatory, Integrative and Comparative Physiology 289:

R1338-R1347, 2005.

. Zhang W and Davenport PW. Activation of thalamic

ventroposteriolateral neurons by phrenic nerve afferents in

cats and rats. Journal of Applied Physiology 94: 220-226,

2003.

. Zhang W*, Fan D, Jiang Y, Zhu Z and Chen N. The role of

nitric oxide in hepatic ischemia-reperfusion injury.

Jiangsu Medical Journal (Chinese) 25: 606-607, 1999.

. Zhang W*, Shi Z, Li P, Shen Y and Chen N. The clinical

analysis of elder diabetic patients complicated with liver

abscess: 11 cases. Practical Geriatrics (Chinese) 13: 28,

1999.

. Zong W, Zhang W and Fan D. Change of serum IL-2 activity

after experimental cerebral ischemia and reperfusion. Acta

Universitatis Medicinalis Nanjing (Chinese) 18: 197-199,

1998.

. Zang Q, Zhang W and Zou Z. Rare extranodal lymphomas: a

clinical study of 11 cases and literature review. Clinical

Oncology Journal (Chinese) 12: 29-32, 1996.

. Han S, Xu Z, Chen L, Zhang Z, Chen Z and Zhang W. The

damage effects of ammonia on gastric mucosa and its

mechanism in mice. Chinese Journal of Internal Medicine 35:

77, 1996.

*: corresponding author

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