Assistant Medical

Susanne Bobadilla, Ph.D

née Schneider

*** **** ***** **

Brooklyn, NY 11238

CELL 917-***-****

E-MAIL: ****************@*****.***

QUALIFICATIONS:

• Scientific Expertise:

o Immunology

o Microbiology

o Infectious diseases (HIV-1/AIDS)

o Autoimmune diseases (Diabetes mellitus type I, Morbus Crohn)

o Metabolic disorders (HFE hereditary hemochromatosis)

o Oncology (RET proto-oncogene, thyroid carcinomas, endocrine neoplasias)

o Hematology

o Vaccines

o Antibody and cell-mediated immunity

o Biochemistry

o Genetics

• Writing Experience:

o Lead author of 4 peer-reviewed publications

o Co-author of 7 peer-reviewed publications

o Authored and submitted NIH fellowship application (F32 NRSA)

o Prepared and presented PowerPoint slide decks for various scientific talks

o Prepared abstracts and posters for various scientific meetings

• Computer Skills:

o Highly proficient in:

Word

Excel

PowerPoint

Adobe Photoshop

• Additional Skills:

o Permanent Resident, green card holder

o Fluent in English and German

o Good knowledge of French and Spanish

EDUCATION/TRAINING:

2009-present Post-doctoral Fellow, Microbial Pathogenesis Program

NYU School of Medicine, New York, NY.

2004-2009 Ph.D., Biochemistry, Cellular and Molecular Biology Program

Weill Cornell Graduate School of Medical Sciences, New York, NY.

1996-1997 Teaching Diploma in Health Science (Hematology, Histology), July 1997

Academy of Health Science Education, Karlsruhe, Germany.

1992-1994 Research Associate Degree, September 1994

Microbiology (Bacteriology, Virology, Serology, Parasitology), Hematology, Histology,

Clinical Chemistry, Anatomy, Physiology, Basic Sciences (organic and inorganic

Chemistry, Biology, Physics).

University of Ulm, Germany.

PROFESSIONAL EXPERIENCE:

09/2009 – present Postdoctoral Fellow

New York University School of Medicine, New York, NY

Department of Microbiology, Laboratory of N. Landau.

08/2004 – 07/2009 Graduate Student

Weill Cornell Graduate School of Medical Sciences, New York, NY

Department of Immunology and Microbiology, Laboratory of B. Schwer.

06/2003 – 07/2004 Research Assistant

European Molecular Biology Laboratory (EMBL), Heidelberg, Germany

Laboratories of M. Muckenthaler (MMPU) and V. Benes (Genomics Core

Facility)

06/1999 – 06/2003 Research Associate

Weill Medical College of Cornell University, New York, NY

Department of Immunology and Microbiology, Laboratory of B. Schwer.

09/1997 – 06/1999 Research Assistant

GATC Biotech AG, Konstanz, Germany

Laboratory of T. Pohl.

03/1995 – 09/1997 Research Assistant

University Hospital of Ulm, Germany

Department of Internal Medicine I, Laboratory of B. O. Boehm.

SKILLS/TECHNIQUES:

• Molecular Biology

Gene cloning, PCR, PCR site-directed mutagenesis, colony PCR, real-time qRT-PCR, RNA and DNA

extraction, cDNA microarrays, Northern and Southern Blotting, generation of mutant gene libraries, in vitro

transcription, DNA and RNA radiolabeling, DNA sequencing, Western Blotting, Thin Layer Chromatography

(GpppA-methylation).

• Biochemistry

Enzyme kinetics and assays (Phosphorylation, ATP-hydrolysis, RNA unwinding, in vitro mRNA splicing,

RNase Protection, RNA binding), recombinant protein expression, protein purification via affinity, ion

exchange and sizing (glycerol gradients, FPLC), antibody purification from immune sera, protein-protein

interaction, immunoprecipitations.

• Mammalian Cell Culture & Virology

Culture of adherent and suspension cell lines, creation of stable cell lines using lentiviral infection, transient

transfection (Lipofectamine 2000, NEON electroporation), luciferase reporter assays, stimulation and analysis

of primary cells (murine splenocytes), FACS.

• Genetics

Standard genetic techniques in budding and fission yeast including generation of knock-out and mutant

strains, analysis of mutant phenotypes by tetrad dissection, assessment of growth phenotypes by spotting,

two-hybrid screening, suppressor screening, inducible expression systems.

TEACHING EXPERIENCE:

2004 Instructor, EMBO Practical Course on Quantification of gene expression by real-time qRT-PCR.

EMBL Heidelberg, Germany

(Course Leader: Vladimir Benes, Ph.D)

• Skills:

o Collaborated on the design of the flyer for the course (concept, layout)

o Led practical part of the course in a classroom setting

MEMBERSHIP IN SCIENTIFIC SOCIETIES:

2009-present New York Academy of Sciences

2004-2009 Student Member, RNA Society

BIBLIOGRAPHY:

A. ARTICLES IN PEER REVIEWED JOURNALS:

Note: Research Papers published under my maiden name (S. Schneider):

Schneider, S., Pei Y., Shuman S. and Schwer B. Separable functions of the fission yeast Spt5

CTD in capping enzyme binding and transcription elongation overlap with those of the RNA

polymerase II CTD Mol. Cell. Biol. 2010; 30(10): 2353-64.

Schwer B., Schneider S., Pei Y., Aronova A. and Shuman S. Characterization of the

Schizosaccharomyces pombe Spt5-Spt4 complex. RNA, 2009; 15(7):1241-50.

Viladevall L., St. Amour C.V., Rosebrock A., Zhang C., Schneider S., Allen J.J., Schwer B.,

Shokat K.M., Leatherwood J.K. and Fisher R.P. TFIIH and P-TEFb Coordinate Transcription

with Capping Enzyme Recruitment at Specific Genes in Fission Yeast. Mol. Cell 2009;

33(6):738-51.

Hausmann S., Ramirez A., Schneider S., Schwer B., Shuman S. Biochemical and genetic

analysis of RNA cap guanine-N2 methyltransferase from Giardia lamblia and

Schizosaccharomyces pombe. Nucleic Acids Res. 2007; 35(5): 1411-1420.

Schwer B., Hausmann S., Schneider S., Shuman S. Poxvirus mRNA cap methyltransferase:

Bypass of the requirement for the stimulatory subunit by mutations in the catalytic subunit and

evidence for intersubunit allostery. J Biol Chem. 2006; 281(28):189**-******.

Auclair S, Feillet-Coudray C, Coudray C, Schneider S, Muckenthaler MU, Mazur A. Mild

copper deficiency alters gene expression of proteins involved in iron metabolism. Blood Cells

Mol Dis. 2006;36:15 -20.

Roy CN, Custodio AO, de Graaf J, Schneider S, Akpan I, Montross LK, Sanchez M, Gaudino A,

Hentze MW, Andrews NC, Muckenthaler MU. An Hfe-dependent pathway mediates

hyposideremia in response to lipopolysaccharide induced inflammation in mice. Nat. Genet.

2004; 36(5):481-5.

Schneider S, Campodonico E, Schwer B. Motifs IV and V in the DEAH box splicing factor

Prp22 are important for RNA unwinding, and helicase defective Prp22 mutants are suppressed by

Prp8. J Biol Chem. 2004; 279(10):8617-26.

Martin A, Schneider S, Schwer B. Prp43 is an essential RNA-dependent ATPase required for

release of lariat-intron from the spliceosome. J Biol Chem.2002; 277(20):17743-50.

Schneider S, Hotz HR, Schwer B. Characterization of dominant-negative mutants of the DEAH-

box splicing factors Prp22 and Prp16. J Biol Chem. 2002;277(18):15452-8.

Schneider S, Schwer B. Functional domains of the yeast splicing factor Prp22. J Biol Chem.

2001; 276(24):21184-91.

B. SEMINAR PRESENTATIONS:

Biochemistry, Cellular and Molecular Biology Scientific Retreat, Skytop, PA. September 4th, 2008.

Functional redundancy of the C-terminal repeat domains of spt5 and rpb1 in recruitment of the capping

enzymes in Schizosaccharomyces pombe.

7th Annual RNA society meeting, University of Wisconsin, Madison, WI, 2002. Prp43, an ATPase required

for release of the lariat-intron from the spliceosome.

Biochemistry, Cellular and Molecular Biology Scientific Retreat, Princeton, NJ. September 7 th, 2001.

ATPases choreograph the splicing cycle.

C. POSTER PRESENTATIONS:

6th Annual RNA society meeting, Banff, Alberta, 2001. Functional domains of the yeast splicing factor

Prp22p.

Biochemistry, Cellular and Molecular Biology Scientific Retreat, Princeton, NJ. September 8 th, 2000.

Slice’n’Splice? – Minimal functional domain of the yeast splicing factor Prp22p.

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