Jason Alexander Ford-Green
Jackson, MS 39216
Cell: 850-***-****
******@*********.***
*****.*.****-*****.***@*****.****.***
PROFESSIONAL PROFILE
1. Highly self-motivated individual with aspirations of achieving at the
highest pinnacles within all aspects of human endeavor
1. A desire to enrich entities with a practical, moral, and ethical
outlook towards success
RESEARCH INTERESTS
My interest lies in the area of molecular modeling and simulation of
signal transduction pathways involving ligands and membrane-bound neuronal
receptors. Wherein I attempt to characterize ligand-enzyme interactions in
the synaptic cleft (QM, QMMD), ligand diffusion via transporter proteins
and ion-channels (Enhanced Sampling MD), reaction pathway determination and
characterization of interactions upon ligand-binding (QM, QMMD, MD), and
small to large-scale dynamical effects upon receptor activation or
inhibition (MD and Normal Mode Analysis). To solve this myriad of issues I
use techniques in the areas of Computational Chemistry, Computational
Molecular Biophysics, and Structural Bioinformatics. I am proficient in
these areas using software and codes such as AMBER11, Gaussian09, GAMESS-
US, SwissModel, 3-D Jigsaw, Gaussview, MOLDEN, Chemcraft, VMD, PoreWalker,
Autodock 4.2, elNemo, Nomad-Ref, BLAST, CLUSTALW algorithm, and the MUSCLE
algorithm.
TEACHING PHILOSOPHY
I wholeheartedly believe that one of the cornerstones in the
development of an individual is rooted in academic achievement. Wherein,
this achievement is precursed by hard work and a willingness to accept new
challenges. The level of a student's success is dictated by these
mainstays. The role of a teacher is to make the student aware of these
truths and to guide a learner along a pathway to their goals. Pushing
students to reach levels that they did not know existed is paramount within
the teaching process and a value that I have benefited from several times
over in my education. If a student is reluctant to work hard or accept new
challenges it then becomes the focus of the teacher to utilize an out-of-
the-box approach towards directing the student. I believe this is where an
educator excels within the realm of teaching and garners the respect of
their students.
Proper Admonition and counseling in matters regarding, not only
academic, but also life-planning gives the teacher an opportunity to be
more than just Socratic in nature. In this century students experience
life in an entirely different way compared to the last. We as teachers
must also be dynamic in our approaches to encourage success through
academic achievement. This platform provides us with the challenge and yet
the opportunity to prepare the student for future endeavors as well as
current. It is to these measures that I owe my teaching philosophy.
EDUCATION
January 2007 to May 2011 (Dissertation Defense February 2011)
Ph.D. Chemistry
Jackson State University
Jackson, Mississippi
August 2004 to December 2006
M.S. Chemistry
Jackson State University
Jackson, Mississippi
August 1999 to May 2004
B.S. Biology
Florida Agricultural & Mechanical University
Tallahassee, Florida
HONORS AND AWARDS
1. 19th Conference on Current Trends in Computational Chemistry (CCTCC)
"honorable mention" poster presentation award (2010)
2. Recipient of a full Travel Fellowship Award to attend the "Summer
School in Biophysics at ORNL: Computational and Experimental
Challenges" in Knoxville, TN (2009)
3. Jackson State University's College of Science Engineering and
Technology Graduate student representative on the H.T. Sampson Library
committee (2008-2010)
4. Modeling and Design of Molecular Materials (MDMM) 2nd place poster
presentation award (2008)
5. 17th Conference on Current Trends in Computational Chemistry (CCTCC)
2nd place poster presentation award (2008)
6. Graduate student award recipient to attend the 57th Annual Meeting of
the Nobel Laureates in Physiology or Medicine in Lindau, Germany via
the National Science Foundation (NSF) Directorate for Mathematical and
Physical Sciences Award (2007)
1. Computational Center for Molecular Structure and Interactions
(CCMSI)/Interdisciplinary Center for Nanotoxicity (ICN) 2006-2009
Lecture Series organizer and moderator
1. CCMSI Summer Institute Mentor and Scientific Evaluator (2005-2008)
1. 13th Conference on Current Trends in Computational Chemistry (CCTCC)
1st place poster presentation award (2004)
1. LSMAMP symposium Plenary Lecture Moderator (2004)
1. RISE Fellowship Award (2004-2005)
1. CCMSI Summer Institute 2nd place student award winner (2003)
1. Congressman Alcee Hastings Scholarship Award recipient (1999)
ASSOCIATIONS/MEMBERSHIPS
1. AAAS Student Member (2008-present)
2. Beta Beta Beta National Honor Society Sigma Epsilon Chapter (2006-
present)
1. Mississippi Academy of Science (2005-present)
1. Toastmasters International Metro Jackson (2005-present)
1. Florida A & M University National Alumni Association (2005-present)
1. American Physics Society (2009-present)
2. American Chemical Society (2004-present)
1. Kappa Alpha Psi Fraternity Incorporated, Jackson Alumni Chapter (2004-
present)
1. Alliance for Graduate Education in Mississippi Scholar (2004-present)
1. National Organization for the Professional Advancement of Black
Chemist and Chemical Engineers (2003-present)
1. American Red Cross Volunteer (1999-present)
RESEARCH EXPERIENCE
(1) U.S. Army Engineer Research and Development Center (Vicksburg)
1 Environmental Laboratory Branch Vicksburg, MS 39180
2 January 2008-Present (Technical Contract Student)
3 Principle Investigator (POC): Edward Perkins Ph.D.
4 Supervising Professors: Jerzy Leszczynski Ph.D., Frances Hill Ph.D.,
Leonid Gorb Ph.D., and Mo Qasim Ph.D.
5 Investigation: Determining pathogenic routes of nitramines (e.g.
RDX, HMX, MNX) in
ligand-gated ion channels of CNS neurons. Structural bioinformatics
programs, i.e. SwissModel and 3DJigsaw, were used along with x-ray
crystal structures to form atomistic models of the quarternary
structures of the N-methyl-d-Aspartate receptor (NMDAR) and GABAAR.
Classical Molecular Dynamics (MD) simulations were used for
equilibration, protein preparation, and production-phase dynamics.
Autodock was used for the thermodynamic calculation of the free energy
of binding of nitramines and their derivatives to these receptors in a
generalized born implicit solvent model and also in gas phase.
(2) Politechnika Wroc?awska (Wroclaw University of Technology)
1 Department of Theoretical Chemistry Wroclaw Poland
2 June 2008 (Visiting Research)
3 Principle Investigator: Jerzy Leszczynski Ph.D. (NSF-CREST)
4 Supervising Professor: Andrezej Sokalski Ph.D.
5 Techniques Learned: Sokalski's method for interaction energy
decomposition
(3) Interdisciplinary Center for Nanotoxicity (ICN)
1. Department of Chemistry Jackson State University Jackson, MS 39217
2. August 2004-Present
3. Principle Investigator: Jerzy Leszczynski Ph.D. (NSF-CREST)
1. Research Mentor: Devashis Majumdar Ph.D.
1. Investigation: Computational conformational analysis on
Organophosphorus (OP) compounds. Ab initio assessment of bond
rotational energy barriers. Thermochemical analysis of solvation
effects to simulate OP compounds entering
enzyme active sites from an aqueous environment. Generation of
molecular electrostatic potential (MEP) surfaces and theoretical
validation of Serine-
OP adduction and phospho-aging pathways in human
AcetylcholineEsterase.
(4) CCMSI Summer Institute for Computational/Theoretical Chemistry
1. Jackson State University Jackson, MS 39217
1. June 2004-July 2004
1. Principle Investigator: Jerzy Leszczynski Ph.D (NSF-CREST)
1. Research Mentor: Yinghong Sheng Ph.D
1. Investigation: Determination of reaction pathway of the 1,3 Dipolar
Cycloaddition reaction between ethylene and nitrile oxide. This
process involved transition state structural determination and
harmonic vibrational characterization. Computational investigation of
HOMO-LUMO energy gaps, and molecular orbital symmetry conducive to
likely overlap for bond formation (Woodward-Hoffman rules).
(5) CCMSI Summer Institute for Computational/Theoretical Chemistry
1. Jackson State University Jackson, MS 39217
1. June 2003-July 2003
1. Principle Investigator: Jerzy Leszczynski Ph.D (NSF-CREST)
1. Research Mentor: Glake Hill Ph.D
1. Investigation: Conducted physi-sorption ab initio analysis on 1,3,5
trichlorbenzene with a SiO2 monolayer. Elucidated energetic
variability with respect to intermolecular distance. Determined the
nature of the interactions i.e. long-range electrostatics, London-
dispersion.
(6) Army High Performance Computing Research Center (AHPCRC) Lab
1. Department of Chemistry Florida A & M University Tallahassee, FL
1. 2003-2004
1. Principle Investigator: Jesse Edwards Ph.D (DOD)
1. Research Mentors: Jesse Edwards Ph.D and Genzo Tanaka Ph.D
1. Investigation: In 2003 compared conformational spaces of soman,
sarin, tabun, gf, and vx gases via molecular dynamical simulations.
This was done to produce a generic pharmacophore of the five gases
that may be targeted after human intoxication occurred. In 2004 used
similar computational methods within a Tripose force-field to assess
conformational flexibility of an HIV-I and HIV-II protease inhibitor
(XI9). Analysis of the active site amino acids responsible for enzyme
catalysis through x-ray crystallographic data. Preparing the molecule
for docking studies.
TEACHING EXPERIENCE
August 2010-present
Adjunct Professor, Comprehensive Academic Resource Program (CARP) Tougaloo
College
Course: Mission: Involvement 101 (MI 101)
January 2007-present
Tutor, Division of Undergraduate Studies Jackson State University
Courses: Chemistry, Biology, Physics, and Calculus II
August 2007-December 2007
Teaching Assistant, Department of Chemistry Jackson State University
Course: General Chemistry 1 Lab (CHML141)
August 2006-December 2006
Teaching Assistant, Department of Chemistry Jackson State University
Course: General Chemistry 1 Lab (CHML141)
SELECTED PRESENTATIONS
1 "Classical Molecular Dynamics Simulations Toward the Understanding of
Nitrosamine Binding Within the N-methyl-D-Aspartate Receptor NR1 S1S2"
Ford-Green, J.; Gorb, L.; Qasim, M.; Perkins, E.; Leszczynski, J.;
Sanibel Symposium, St. Simmons, GA U.S.A., February 2009
2 "Conformational studies of organophosphorus pesticides towards the
discernment of their esterase inhibition" Ford-Green, J.; Majumdar,
Devashis; Leszczynski, Jerzy; Modeling & Design of Molecular Materials
Conference, Piechowice, Poland, June 2008
3 "Theoretical Comparison of Parathion and Paraoxon for the Discernment
of Acetylcholinesterase-Phosphorothioate Inhibition" Ford-Green, J.;
Majumdar, Devashis; Leszczynski, Jerzy; 2007 ICMR workshop;
University of Zululand, Richards Bay, Republic of South Africa, July
2007
4 "Conformatonal Analysis of 3 Separate Qualitative Biologically Active
?-hydroxyphosphonate Derivatives" Ford-Green, J.; Majumdar, Devashis;
Leszczynski, Jerzy; 15th Annual CCTCC, Jackson, MS U.S.A., November
2006
5 "Theoretical Conformational Analysis on Parathion" Ford-Green, J.;
Majumdar, Devashis; Leszczynski, Jerzy; U.S. Army Engineering Research
and Development Center, Vicksburg, MS U.S.A., July 2006
6 "DFT Study on the Reaction Mechanism of the 1, 3-Dipolar Cycloaddition
Between Ethene and Nitrile Oxide" Ford-Green, J.; Hassan, Ayourinde;
Sheng, Yenghong; Leszczynski, Jerzy; Modelling and Design of Molecular
Materials Conference, Wroclaw, Poland, September 2004
7 "Elucidating Van der Waals interactions between SiO2 and 1,3,5
trichlorobenzene" Ford-Green, J.; Hill, Glake; Leszczynski, Jerzy;
Modeling Interactions in Biomolecules Workshop, Nove Hrady, Czech
Republic, September 2003
TECHNICAL WORKSHOPS ATTENDED
1. Methods and Applications of Hybrid QM/MM Simulations to Biomolecular
Systems; September 10-13, 2007; Pittsburgh Supercomputing Center, 300
S. Craig Street, Pittsburgh, PA
PUBLICATIONS
1. Ford-Green, J., Isayev, A., Gorb, L., Leszczynski, J., Perkins, E.,
Evaluation of Natural and Nitramine Binding Free Energy to 3-D Models
of the Transmembrane and S1S2 Domains in the Human N-Methyl-D-
Aspartate Receptor, Submitted for Review, 2010.
2. Ford-Green, J., Majumdar, D., Leszczynski, J., Probing the Active
Conformers of Paraoxon Through Theoretical Conformational Studies,
Collection of Czechoslovak Chemical Communications, 2008, 73, 10, 1245-
1260.
3. Ford-Green, J., Majumdar, D., Leszczynski, J., Conformational Studies
on Parathion, International Journal of Quantum Chemistry, 2006, 11,
106, 2356-2365.
REFERENCES
. Leszczynski, Jerzy, Ph.D., Distinguished Professor, Department of
Chemistry, Jackson State University, Jackson, MS Phone: 601-***-****,
*****@*********.***
. Edwards, Jesse, Ph.D., Associate Professor, Department of Chemistry,
Florida A & M University, Tallahassee, FL Phone: 850-***-****,
*****.*******@****.***
. Hill, Glake A., Ph.D., Assistant Professor, Department of Chemistry,
Jackson State University, Jackson, MS Phone: 601-***-****,
******@*********.***
. Hamme, Ashton, Ph.D., Associate Professor, Department of Chemistry,
Jackson State University, Jackson, MS Phone: 601-***-****,
******.*.*****.@*****.***
. Sadrud-Din, Sakeenah, Ph.D., Assistant Professor, Department of
Biology, Tallahassee Community College, Tallahassee, FL Phone: 850-201-
6200, e-mail address distributed as needed
. Perkins, Edward, Ph.D., Research Biologist, Environmental Laboratory,
U.S. Army Engineer Research and Development Center (Vicksburg, MS)
Phone: 601-***-****, ******.*.*******@*****.****.***
GPA
As of the Fall Semester of 2010 my cumulative GPA is 3.95