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Engineer Assistant

Location:
Jackson, MS, 39216
Posted:
December 08, 2010

Contact this candidate

Resume:

Jason Alexander Ford-Green

**** ******* **.

Jackson, MS 39216

Cell: 850-***-****

******@*********.***

*****.*.****-*****.***@*****.****.***

PROFESSIONAL PROFILE

1. Highly self-motivated individual with aspirations of achieving at the

highest pinnacles within all aspects of human endeavor

1. A desire to enrich entities with a practical, moral, and ethical

outlook towards success

RESEARCH INTERESTS

My interest lies in the area of molecular modeling and simulation of

signal transduction pathways involving ligands and membrane-bound neuronal

receptors. Wherein I attempt to characterize ligand-enzyme interactions in

the synaptic cleft (QM, QMMD), ligand diffusion via transporter proteins

and ion-channels (Enhanced Sampling MD), reaction pathway determination and

characterization of interactions upon ligand-binding (QM, QMMD, MD), and

small to large-scale dynamical effects upon receptor activation or

inhibition (MD and Normal Mode Analysis). To solve this myriad of issues I

use techniques in the areas of Computational Chemistry, Computational

Molecular Biophysics, and Structural Bioinformatics. I am proficient in

these areas using software and codes such as AMBER11, Gaussian09, GAMESS-

US, SwissModel, 3-D Jigsaw, Gaussview, MOLDEN, Chemcraft, VMD, PoreWalker,

Autodock 4.2, elNemo, Nomad-Ref, BLAST, CLUSTALW algorithm, and the MUSCLE

algorithm.

TEACHING PHILOSOPHY

I wholeheartedly believe that one of the cornerstones in the

development of an individual is rooted in academic achievement. Wherein,

this achievement is precursed by hard work and a willingness to accept new

challenges. The level of a student's success is dictated by these

mainstays. The role of a teacher is to make the student aware of these

truths and to guide a learner along a pathway to their goals. Pushing

students to reach levels that they did not know existed is paramount within

the teaching process and a value that I have benefited from several times

over in my education. If a student is reluctant to work hard or accept new

challenges it then becomes the focus of the teacher to utilize an out-of-

the-box approach towards directing the student. I believe this is where an

educator excels within the realm of teaching and garners the respect of

their students.

Proper Admonition and counseling in matters regarding, not only

academic, but also life-planning gives the teacher an opportunity to be

more than just Socratic in nature. In this century students experience

life in an entirely different way compared to the last. We as teachers

must also be dynamic in our approaches to encourage success through

academic achievement. This platform provides us with the challenge and yet

the opportunity to prepare the student for future endeavors as well as

current. It is to these measures that I owe my teaching philosophy.

EDUCATION

January 2007 to May 2011 (Dissertation Defense February 2011)

Ph.D. Chemistry

Jackson State University

Jackson, Mississippi

August 2004 to December 2006

M.S. Chemistry

Jackson State University

Jackson, Mississippi

August 1999 to May 2004

B.S. Biology

Florida Agricultural & Mechanical University

Tallahassee, Florida

HONORS AND AWARDS

1. 19th Conference on Current Trends in Computational Chemistry (CCTCC)

"honorable mention" poster presentation award (2010)

2. Recipient of a full Travel Fellowship Award to attend the "Summer

School in Biophysics at ORNL: Computational and Experimental

Challenges" in Knoxville, TN (2009)

3. Jackson State University's College of Science Engineering and

Technology Graduate student representative on the H.T. Sampson Library

committee (2008-2010)

4. Modeling and Design of Molecular Materials (MDMM) 2nd place poster

presentation award (2008)

5. 17th Conference on Current Trends in Computational Chemistry (CCTCC)

2nd place poster presentation award (2008)

6. Graduate student award recipient to attend the 57th Annual Meeting of

the Nobel Laureates in Physiology or Medicine in Lindau, Germany via

the National Science Foundation (NSF) Directorate for Mathematical and

Physical Sciences Award (2007)

1. Computational Center for Molecular Structure and Interactions

(CCMSI)/Interdisciplinary Center for Nanotoxicity (ICN) 2006-2009

Lecture Series organizer and moderator

1. CCMSI Summer Institute Mentor and Scientific Evaluator (2005-2008)

1. 13th Conference on Current Trends in Computational Chemistry (CCTCC)

1st place poster presentation award (2004)

1. LSMAMP symposium Plenary Lecture Moderator (2004)

1. RISE Fellowship Award (2004-2005)

1. CCMSI Summer Institute 2nd place student award winner (2003)

1. Congressman Alcee Hastings Scholarship Award recipient (1999)

ASSOCIATIONS/MEMBERSHIPS

1. AAAS Student Member (2008-present)

2. Beta Beta Beta National Honor Society Sigma Epsilon Chapter (2006-

present)

1. Mississippi Academy of Science (2005-present)

1. Toastmasters International Metro Jackson (2005-present)

1. Florida A & M University National Alumni Association (2005-present)

1. American Physics Society (2009-present)

2. American Chemical Society (2004-present)

1. Kappa Alpha Psi Fraternity Incorporated, Jackson Alumni Chapter (2004-

present)

1. Alliance for Graduate Education in Mississippi Scholar (2004-present)

1. National Organization for the Professional Advancement of Black

Chemist and Chemical Engineers (2003-present)

1. American Red Cross Volunteer (1999-present)

RESEARCH EXPERIENCE

(1) U.S. Army Engineer Research and Development Center (Vicksburg)

1 Environmental Laboratory Branch Vicksburg, MS 39180

2 January 2008-Present (Technical Contract Student)

3 Principle Investigator (POC): Edward Perkins Ph.D.

4 Supervising Professors: Jerzy Leszczynski Ph.D., Frances Hill Ph.D.,

Leonid Gorb Ph.D., and Mo Qasim Ph.D.

5 Investigation: Determining pathogenic routes of nitramines (e.g.

RDX, HMX, MNX) in

ligand-gated ion channels of CNS neurons. Structural bioinformatics

programs, i.e. SwissModel and 3DJigsaw, were used along with x-ray

crystal structures to form atomistic models of the quarternary

structures of the N-methyl-d-Aspartate receptor (NMDAR) and GABAAR.

Classical Molecular Dynamics (MD) simulations were used for

equilibration, protein preparation, and production-phase dynamics.

Autodock was used for the thermodynamic calculation of the free energy

of binding of nitramines and their derivatives to these receptors in a

generalized born implicit solvent model and also in gas phase.

(2) Politechnika Wroc?awska (Wroclaw University of Technology)

1 Department of Theoretical Chemistry Wroclaw Poland

2 June 2008 (Visiting Research)

3 Principle Investigator: Jerzy Leszczynski Ph.D. (NSF-CREST)

4 Supervising Professor: Andrezej Sokalski Ph.D.

5 Techniques Learned: Sokalski's method for interaction energy

decomposition

(3) Interdisciplinary Center for Nanotoxicity (ICN)

1. Department of Chemistry Jackson State University Jackson, MS 39217

2. August 2004-Present

3. Principle Investigator: Jerzy Leszczynski Ph.D. (NSF-CREST)

1. Research Mentor: Devashis Majumdar Ph.D.

1. Investigation: Computational conformational analysis on

Organophosphorus (OP) compounds. Ab initio assessment of bond

rotational energy barriers. Thermochemical analysis of solvation

effects to simulate OP compounds entering

enzyme active sites from an aqueous environment. Generation of

molecular electrostatic potential (MEP) surfaces and theoretical

validation of Serine-

OP adduction and phospho-aging pathways in human

AcetylcholineEsterase.

(4) CCMSI Summer Institute for Computational/Theoretical Chemistry

1. Jackson State University Jackson, MS 39217

1. June 2004-July 2004

1. Principle Investigator: Jerzy Leszczynski Ph.D (NSF-CREST)

1. Research Mentor: Yinghong Sheng Ph.D

1. Investigation: Determination of reaction pathway of the 1,3 Dipolar

Cycloaddition reaction between ethylene and nitrile oxide. This

process involved transition state structural determination and

harmonic vibrational characterization. Computational investigation of

HOMO-LUMO energy gaps, and molecular orbital symmetry conducive to

likely overlap for bond formation (Woodward-Hoffman rules).

(5) CCMSI Summer Institute for Computational/Theoretical Chemistry

1. Jackson State University Jackson, MS 39217

1. June 2003-July 2003

1. Principle Investigator: Jerzy Leszczynski Ph.D (NSF-CREST)

1. Research Mentor: Glake Hill Ph.D

1. Investigation: Conducted physi-sorption ab initio analysis on 1,3,5

trichlorbenzene with a SiO2 monolayer. Elucidated energetic

variability with respect to intermolecular distance. Determined the

nature of the interactions i.e. long-range electrostatics, London-

dispersion.

(6) Army High Performance Computing Research Center (AHPCRC) Lab

1. Department of Chemistry Florida A & M University Tallahassee, FL

1. 2003-2004

1. Principle Investigator: Jesse Edwards Ph.D (DOD)

1. Research Mentors: Jesse Edwards Ph.D and Genzo Tanaka Ph.D

1. Investigation: In 2003 compared conformational spaces of soman,

sarin, tabun, gf, and vx gases via molecular dynamical simulations.

This was done to produce a generic pharmacophore of the five gases

that may be targeted after human intoxication occurred. In 2004 used

similar computational methods within a Tripose force-field to assess

conformational flexibility of an HIV-I and HIV-II protease inhibitor

(XI9). Analysis of the active site amino acids responsible for enzyme

catalysis through x-ray crystallographic data. Preparing the molecule

for docking studies.

TEACHING EXPERIENCE

August 2010-present

Adjunct Professor, Comprehensive Academic Resource Program (CARP) Tougaloo

College

Course: Mission: Involvement 101 (MI 101)

January 2007-present

Tutor, Division of Undergraduate Studies Jackson State University

Courses: Chemistry, Biology, Physics, and Calculus II

August 2007-December 2007

Teaching Assistant, Department of Chemistry Jackson State University

Course: General Chemistry 1 Lab (CHML141)

August 2006-December 2006

Teaching Assistant, Department of Chemistry Jackson State University

Course: General Chemistry 1 Lab (CHML141)

SELECTED PRESENTATIONS

1 "Classical Molecular Dynamics Simulations Toward the Understanding of

Nitrosamine Binding Within the N-methyl-D-Aspartate Receptor NR1 S1S2"

Ford-Green, J.; Gorb, L.; Qasim, M.; Perkins, E.; Leszczynski, J.;

Sanibel Symposium, St. Simmons, GA U.S.A., February 2009

2 "Conformational studies of organophosphorus pesticides towards the

discernment of their esterase inhibition" Ford-Green, J.; Majumdar,

Devashis; Leszczynski, Jerzy; Modeling & Design of Molecular Materials

Conference, Piechowice, Poland, June 2008

3 "Theoretical Comparison of Parathion and Paraoxon for the Discernment

of Acetylcholinesterase-Phosphorothioate Inhibition" Ford-Green, J.;

Majumdar, Devashis; Leszczynski, Jerzy; 2007 ICMR workshop;

University of Zululand, Richards Bay, Republic of South Africa, July

2007

4 "Conformatonal Analysis of 3 Separate Qualitative Biologically Active

?-hydroxyphosphonate Derivatives" Ford-Green, J.; Majumdar, Devashis;

Leszczynski, Jerzy; 15th Annual CCTCC, Jackson, MS U.S.A., November

2006

5 "Theoretical Conformational Analysis on Parathion" Ford-Green, J.;

Majumdar, Devashis; Leszczynski, Jerzy; U.S. Army Engineering Research

and Development Center, Vicksburg, MS U.S.A., July 2006

6 "DFT Study on the Reaction Mechanism of the 1, 3-Dipolar Cycloaddition

Between Ethene and Nitrile Oxide" Ford-Green, J.; Hassan, Ayourinde;

Sheng, Yenghong; Leszczynski, Jerzy; Modelling and Design of Molecular

Materials Conference, Wroclaw, Poland, September 2004

7 "Elucidating Van der Waals interactions between SiO2 and 1,3,5

trichlorobenzene" Ford-Green, J.; Hill, Glake; Leszczynski, Jerzy;

Modeling Interactions in Biomolecules Workshop, Nove Hrady, Czech

Republic, September 2003

TECHNICAL WORKSHOPS ATTENDED

1. Methods and Applications of Hybrid QM/MM Simulations to Biomolecular

Systems; September 10-13, 2007; Pittsburgh Supercomputing Center, 300

S. Craig Street, Pittsburgh, PA

PUBLICATIONS

1. Ford-Green, J., Isayev, A., Gorb, L., Leszczynski, J., Perkins, E.,

Evaluation of Natural and Nitramine Binding Free Energy to 3-D Models

of the Transmembrane and S1S2 Domains in the Human N-Methyl-D-

Aspartate Receptor, Submitted for Review, 2010.

2. Ford-Green, J., Majumdar, D., Leszczynski, J., Probing the Active

Conformers of Paraoxon Through Theoretical Conformational Studies,

Collection of Czechoslovak Chemical Communications, 2008, 73, 10, 1245-

1260.

3. Ford-Green, J., Majumdar, D., Leszczynski, J., Conformational Studies

on Parathion, International Journal of Quantum Chemistry, 2006, 11,

106, 2356-2365.

REFERENCES

. Leszczynski, Jerzy, Ph.D., Distinguished Professor, Department of

Chemistry, Jackson State University, Jackson, MS Phone: 601-***-****,

*****@*********.***

. Edwards, Jesse, Ph.D., Associate Professor, Department of Chemistry,

Florida A & M University, Tallahassee, FL Phone: 850-***-****,

*****.*******@****.***

. Hill, Glake A., Ph.D., Assistant Professor, Department of Chemistry,

Jackson State University, Jackson, MS Phone: 601-***-****,

******@*********.***

. Hamme, Ashton, Ph.D., Associate Professor, Department of Chemistry,

Jackson State University, Jackson, MS Phone: 601-***-****,

******.*.*****.@*****.***

. Sadrud-Din, Sakeenah, Ph.D., Assistant Professor, Department of

Biology, Tallahassee Community College, Tallahassee, FL Phone: 850-201-

6200, e-mail address distributed as needed

. Perkins, Edward, Ph.D., Research Biologist, Environmental Laboratory,

U.S. Army Engineer Research and Development Center (Vicksburg, MS)

Phone: 601-***-****, ******.*.*******@*****.****.***

GPA

As of the Fall Semester of 2010 my cumulative GPA is 3.95



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