Project Data

Ana Cobani

*** ***** ******, ************, ** ***25

215-***-**** . *******@*****.***

PROFILE

Technical strengths: Years of hands-on experience with multiple laboratory

instruments most often used in analysis of pharmaceutical molecules coupled

with data report writing.

Project Coordination and Team Work: Highly productive member in a team

environment. Efficient in handling multiple project priorities.

Communication: Effective listener and able to communicate technical

information to multiple teams.

Personal Attributes: Dependable. Highly organized. Ability to think

critically. Sense of humor.

PROFESSIONAL EXPERIENCE

Pfizer Inc., Groton, Connecticut (2002-2010)

Senior Research Associate in AR&D (2007-2010)

Responsible for validating test methods adhering to SOPs. Used screening LC-

MS instruments to identify process-related impurities. Analyzed, recorded

data according to SOPs and communicated results. Maintained laboratory

instruments, ordered supplies and prepared buffers. Supported the

formulating team with determination of the glass transition of Sprayed

Dried Dispersion formulations using Differential Scanning Calorimetry.

Senior Research Associate in PharmR&D (2007-2010)

Worked in the area of solid-state characterization, crystallization,

polymorphism and salt selection of organic molecules. Assisted project

leader in designing polymorph and hydrate screen. Performed full

characterization of the solid-state forms, made conclusions about their

thermodynamic stability and wrote full data reports. Performed routine

analysis using various analytical instruments and techniques to assess the

physical stability of early stage API.

EDUCATION

Bachelors of Science in Chemistry, cum laude, Temple University,

Philadelphia, PA, 2002

Organic chemistry research in collaboration with Professor Grant R. Krow

(Temple University). Studied the synthesis and reactivity of

conformationally strained proline analogs. (2001- 2002)

ACADEMIC AWARDS

Recipient of Bristol-Myers Squibb Undergraduate Research Fellowship, 2002

ANALYTICAL SKILLS

Analytical Skills

. Hands-on experience with chromatographic techniques including HPLC

and LC-MS

. Extensive experience with collection and interpretation of

Differential Scanning Calorimetry, Thermal Gravimetric Analysis and

X-ray Powder Diffraction data

. Hands-on experience with methods for the structural and physical

characterization of organic molecules, including NMR, FT-IR,

Polarized Light Microscopy, SEM and Mass Spectroscopy

. Proficient with software including Microsoft Excel, Word,

PowerPoint, ISIS Base/Draw, Waters Empower, ACD Labs

Leadership Duties

. Department point of contact for training colleagues in Differential

Scanning Calorimetry and Thermal Gravimetric Analysis techniques

. Coordinating monthly group meetings

. Writing a laboratory manual for using the FT-IR Microscope

Technical Skills

. Designing polymorph, hydrate and salt screens for pharmaceutical

compounds

. Growing single crystals of organic compounds for X-ray analysis

. Experience using small-scale multi-reactor synthesizer

JOB RELATED TRAINING / COURSES

. Graduate course in Analytical Chemistry, University of Rhode

Island, Kingston, RI, Spring 2009

. Graduate course in Inorganic Chemistry, University of Rhode Island,

Kingston, RI, Fall 2008

. Raman Microscopy course, McCrone Institute, Chicago, IL, 2006

. Graduate course in Statistical Thermodynamic, University of Rhode

Island, Kingston, RI, Spring 2005

. Pharmaceutical Microscopy course at the McCrone Institute, Chicago,

IL 2003

PUBLICATIONS

Brendan J. Murphy, Jun Huang, Melissa J. Casteel, Ana Cobani, Joseph F.

Krzyzaniak, Varenicline L-tartrate crystal forms: Characterization through

crystallography, spectroscopy, and thermodynamics. Journal of

Pharmaceutical Sciences (2010), V.99 (6), 2766-2777

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