Project Assistant

Dr. Manashi Chatterjee

Department of Chemistry

University of Nebraska, Lincoln (UNL)

Lincoln, Nebraska, USA

************@********.***.***

********@*****.**

Tel: 1-402-***-****; Tel: 1-310-***-**** (cell)

RESEARCH SKILLS ACQUIRED

Eleven years of research experience (3 years of pre-Ph.D. training after M.Sc. followed by 6 years of Ph.D.

work and 2 years of postdoctoral research) in the field of synthetic organic and bio-organic chemistry,

Multi-step synthesis of various glycosidase inhibitors using carbohydrate chemistry, various DNA binding

ligands using heterocyclic chemistry and design and synthesis of new molecular level architectures:

‘molecular machines’.

Trained in handling multi-step organic synthesis involving functional group transformations, using air-

sensitive reagents, planning and conducting synthesis of organic molecules (heterocyclic systems and

peptides). Extensively used NMR spectrometer (1H, 13C), IR, UV, CD and Fluorescence spectrophotometer

to characterize and study DNA-ligand complexation.

Acquired sound knowledge of computer applications like chemical structure drawing, Excel and word

processing. Extensively used Sci-finder, patent searches and other inter-net searches to dig out scientific

information and literature to solve synthetic problems.

Strong leadership skills, provide scientific briefings/presentations in front of large audiences, sharing

information between different groups of workers, training of staff in new skills and procedures, developing

training courses.

Establish priorities, create and maintain timeframes and deadlines of assigned projects.

Remain current with internal and scientific literature to maintain and expand relevant knowledge and apply

new knowledge to project responsibilities.

Experienced in training and supervising undergraduates with basic organic synthetic techniques.

Excellent verbal communication, teaching and writing skills.

Able to work independently as well as within a team based environment.

EDUCATIONAL BACKGROUND

2004-2006 University of Edinburgh Scotland, UK

Post-doctoral Fellow

Professor David A. Leigh’s Laboratory

1997 - 2004 University of Saskatchewan Saskatoon, Canada

Ph.D. (Organic Chemistry)

Thesis Title: "Versatile Design Strategies and Generation of Novel DNA Sequence targeted Ligands"

Graduate Study Cumulative Average: 88.83 %

1991 - 1993 Indian Institute of Technology (IIT) Bombay, India

M.Sc. (Organic Chemistry)

Thesis Title: “Bioorganic Studies in Liposomes: Casein Retenoid Interactions”.

Grade: Placed in First Division

ACEDAMIC POSITIONS

Organic Chemistry Lecturer (August 2008 – present)

Department of Chemistry

University of Nebraska, Lincoln (UNL)

Lincoln, Nebraska, USA

Organic Chemistry Lecturer (July 2006 – July 2008)

Department of Chemistry & Biochemistry

Instructional Division

University of California (UCLA); Los Angeles, California, USA

AWARDS AND COMPETITIVE EXAMS QUALIFIED

Academic Advancement Program (AAP) Awards Recipients (January 16, 2008)

Commended for being exceptionally receptive to, and supportive of, AAP's tutors' efforts to help AAP students

deepen their learning and attain academic excellence. The awards was conferred at an AAP Faculty Recognition

Reception on January 16, 2008.

UCLA-CNSI Staff Appreciation Award (November 2006)

Post Doctoral Research Fellowship (2004-2006) at the University of Edinburgh, School of Chemistry.

Herzberg Fellowship (2002-2003) at the University of Saskatchewan (in the honour of Dr. Gerhard

Herzberg, 1971 Nobel Laureate in Chemistry) awarded to the outstanding student in basic physical sciences

with an interest in spectroscopy.

Dr. O. Kenneth Johannson Memorial Scholarship (1998-1999) at University of Saskatchewan, to

recognize contributions as the best teaching assistant of the year.

Graduate Teaching Fellowship and University Scholarship (1997-Dec 2003) at University of

Saskatchewan, to pursue Ph.D. program.

Alumini Travel Award from College of Graduate studies and research to attend 81st Canadian Society for

Chemistry conference May 31-June 4, 1998 at Whistler.

University President/Student Fund as conference travel support, to present research at 11th Conversation

in Biomolecular Stereodynamics at Albany, New York, USA. (June15-19, 1999)

Graduate Student Fellowship (1997) at Auburn University, Alabama, USA to pursue Ph.D. program.

(Did not enroll)

Senior Research Fellowship (1996) under Council of Scientific and Industrial Research (CSIR) awarded

by Government of India for research in chemical sciences.

Qualified State Eligibility Test for Lectureship (SET-1995)

Qualified Graduate Aptitude Test in Engineering (GATE-93) Score: 87.47 percentile

PARTICIPATED IN PROFESSIONAL DEVELOPMENT PRESENTATIONS AT UNL:

The ADVANCE office hosts a series of bi-weekly or monthly short and focused conversations on recruitment,

retention, promotion, and leadership topics, that involve both faculty leaders and the members of the ADVANCE

Recruit and Promote committees as facilitators/presenter http://advance.unl.edu/events/

Rising Above the Gathering Storm: Teaching to Attract STEM Majors

If I were in Charge: Opportunities to Become a Campus Leader

Special presentation by Carol Geary Schneider, president of the Association of American Colleges and

Universities; one-day symposium celebrating UNL's efforts to improve undergraduate education; celebrate

UNL's first year of Achievement-Centered Education and our ongoing work to enhance teaching, learning,

and assessment through efforts such as the Peer Review of Teaching Project; the Faculty Leadership for

Writing Initiative; Program Excellence through Assessment, Research, and Learning; and Liberal

Education and America's Promise.

"The Road Ahead: Intentional and Integrative Learning at UNL,"

PUBLICATIONS

1. J. Am. Chem. Soc. 2006, 128, 4058

Beyond switches: Ratcheting a particle energetically uphill with a compartmentalized molecular machine.

Manashi N. Chatterjee, Euan R. Kay and David A. Leigh

http://pubs.acs.org/cgi-bin/abstract.cgi/jacsat/2006/128/i12/abs/ja057664z.html

(Listed among one of the 2006 JACS top 20 highly sited papers)

http://pubs.acs.org/journals/jacsat/promo/most/most_cited/2006.html

2. World Intellectual Property Organization (WIPO)

Publication Number: (WO/2007/045096)

International Application No.: PCT/CA2006/001724

Title: Oligoheteroaromatic luminescent assemblies as high-affinity DNA sequence directed ligands.

M. P. Singh and M. N. Chatterjee

http://www.wipo.int/pctdb/en/wo.jsp?wo=200-***-****&IA=WO2007045096&DISPLAY=STATUS

3. Synthesis 2000, 10, 1380

Synthetic utilities of catalytic Fe (III)/Fe (II) redox cycling towards fused heterocycles: A facile access to substituted

benzimidazole, bis-benzimidazole and imidazopyridine derivatives.

M. P. Singh, S. Sasmal, W. Lu, and M. Chatterjee

http://www.thieme-connect.com/DOI/DOI?10.1055/s-2000-7111

4. Res. Chem. Intermed. 1999, 25, 887

Protecting group directed chemo and stereo selective transformations of bis-epoxides and cyclic sulfates derived

from hexoses : synthesis of 2,5-dihydroxymethyl-3,4-dihydroxypyrrolidine.

B.B. Lohray, Vidya Bhushan, M. Chatterjee, Y. Jayamma and G. Prasuna

5. Synthetic Communications 1997, 27, 1711

A Practical approach to the synthesis of dianhydro sugars: Effect of protecting groups on the course of the reaction.

B. B. Lohray, M. Chatterjee, Y. Jayamma

6. J. Org. Chem. 1995, 60, 5958

Unprecedented selectivity in the reaction of 1,2: 5,6- Dianhydro-3, 4-O-isopropylidene hexitols with benzyl amine.

A practical synthesis of 3,4,5,6-tetrahydroxyazepanes.

B. B. Lohray, Y. Jayamma, M. Chatterjee

http://pubs3.acs.org/acs/journals/supporting_information.page?in_manuscript=jo00123a037

SEMINAR AND CONFERENCE PRESENTATIONS

1. Poster Presentation at the First Joint International Symposium on Macrocyclic and Supramolecular

Chemistry (ISMSC) at Victoria, BC, Canada (June 25 - June 30, 2006)

Beyond switches: Ratcheting a particle energetically uphill with a compartmentalized molecular machine.

Manashi N. Chatterjee, Stephen M. Goldup, Euan R. Kay and David A. Leigh

2. Poster Presentation at the ACS 229th National Meeting at San Diego, CA, USA (March 13- March 17, 2005)

Poster Title: How do Simple Molecular level Machines Perform Tasks?

Manashi N. Chatterjee, Euan R. Kay and David A. Leigh

3. Invited Research talk at University of California San Francisco (UCSF), California,USA (September 2002)

Talk entitled “Iterative Design & Development of a New Class of DNA Sequence-Directed Molecules.”

with Professor Fred Cohen’s group; Department of Pharmaceutical Chemistry & Department of Cellular and

Molecular Pharmacology

Was offered postdoctoral position will full funding beginning September 2003; could not join as thesis my defense

was postponed to December 2003.

Manashi Chatterjee

4. Invited Research talk at Lawrence Berkeley National Laboratory, Berkeley, California, (September 2002)

Talk entitled “Iterative Design & Development of a New Class of DNA Sequence-Directed Molecules.”

with the Chemistry Group ; Principle Scientist Dr. Van Brocklin, H. (Nuclear Medicine and Functional Imaging

Laboratory)

Manashi Chatterjee

5. Invited Research talk at The Scripps Research Institute (TSRI), La Jolla, California, (May 2002)

Talk entitled “Iterative Design & Development of a New Class of DNA Sequence-Directed Molecules.”

with Professor Joyce, Gerald’s group (Molecular Biology and Chemistry Laboratory)

Manashi Chatterjee

6. University of Saskatchewan, Dept. of Chemistry (Oct. 23, 2001)

Graduate Seminar entitled “Iterative Design & Development of a New Class of DNA Sequence-Directed

Molecules.”

Manashi Chatterjee

7. The 83rd Canadian Society for Chemistry (CSC 2000), Calgary, Alberta (May 27, 2000)

Benzimidazole-tagged polyamides and extended covalently linked dimers as design paradigms for high affinity/

selectivity in DNA sequence recognition. (0631)

M. Chatterjee, M. P. Singh

Designer fluorescent ligands for targeting specific DNA sequence subsets. (0630)

S. Sasmal, M. Chatterjee, M. P. Singh

8. 11th Conversation in Biomolecular Stereodynamics, Albany, New York, USA (June15, 1999)

Modular assemblies and characterization of DNA minor groove binders- Part I. Nylon-like amide linkers in the

design of covalently-linked dystamycin dimer.

M. Chatterjee, A. Dyck, M. P. Singh

9. 81st Canadian Society for Chemistry (CSC 1998), Whistler, B. C (May 31, 1998)

Optical geometric and requirements for aliphatic polyamides in binding to DNA minor groove.

M. Chatterjee, A. Dyck, M. P. Singh

PERSONAL INFORMATION

Nationality: Canadian.

Member of American Chemical Society (membership number: 2379291)

WORK EXPERIENCE

August 2008 – present

Lecturer Organic Chemistry

UNL, Department of Chemistry, Nebraska, USA

Instructor for undergraduate chemistry course for life science majors:

Chem 251 (Chemical Dynamics and Reactivity: Introduction to Organic Chemistry) during the following

semesters: Fall 2008, Spring 2009, Summer 2009, Fall 2009, Spring 2010, Summer 2010, Fall 2010, Spring

2011;Summer 2011

Chem 252 (Organic Chemistry: Reactivity and Synthesis) during, Summer 2009, Spring 2009, Fall 2010,

Spring 2011,Summer 2011

Chem 109 (General Chemistry): Fall 2009

Supervised Teaching Assistants. Taught over 1000 students during the 2008-2011.

Mentored UTAC Teaching Assistant-Fall 2010, Spring 2011

Awarded: UCARE:2009-2010 UCARE funding for the

2009-10 academic year for project “Exploring the use of heteroaromatic pyrrole, imidazole and

benzimidazole aldehydes as components in Biginelli and Hantzsch cyclocondensations.” The UCARE

stipend awarded to Amy Mayer is $2000. (Discontinued since student decided to drop out)

Participated in “Chemistry Day” and other outreach activities.

Participated in summer school teaching programs

July 2006 – July 2008

Lecturer Organic Chemistry

UCLA, Department of Chemistry and Biochemistry, California, USA

Instructor for undergraduate chemistry course:

Chem 30 A (Chemical Dynamics and Reactivity: Introduction to Organic Chemistry) during Fall 2006, Winter

2007, Spring 2007, Winter 2008 and Spring 2008

Chem 30 B (Organic Chemistry: Reactivity and Synthesis Part I) during Summer C 2007, Fall 2007 and Spring

2008

Chem 14 BL (Chemistry experiments for life science majors): Summer 2008

Supervised 18 Teaching assistants during the last 6 quarters. Teaching over 1000 students during the last 6

quarters

Worked with the CNSI at UCLA in projects listed below:

Managed two training grants that are being run under the umbrella of the CNSI: Nanotoxicology training

Program and the Research Experience for Undergraduates (NSF-REU) in Nanosystems Chemistry and

Engineering Research (NanoCER) program

Co-PI in the NSF funded Research Experience for Undergraduates (REU)-NanoCER program - Summer

of 2007 http://www.nsf.gov/crssprgm/reu/list_result.cfm?unitid=5048

Participated in a new course development for the Nanotoxicology Training Program which started fall 2007

Organize and expand Outreach activities of the CNSI: Attending the California Forums for Diversity in

Graduate Education to promote our programs and also promoting NanoScience Education in the LA

Unified School District

Help and assist faculty seek new grant applications for new training programs

Oversee CNSI Education Website development

Oversee CNSI fellowship applications

June 2004 - May 2006

Post Doctoral Research Associate

University of Edinburgh, Scotland, UK

Synthesis of some novel molecular systems containing interlocked molecules called ‘rotaxanes’ towards

understanding the principles behind how simple molecules perform mechanical tasks in Professor David

Leigh’s group.

Sept. 1997- Dec. 2003

Graduate Student (full time) &

Graduate Teaching Fellow/Teaching Assistant

Dept. of Chemistry, University of Saskatchewan, Canada

Was working towards Ph. D. degree requirements (research and course work) under the supervision of

Professor M.P. Singh.

Responsible for conducting and teaching undergraduate labs, tutorials, grading assignments, reports and

exams for ~ 40 students per term.

Laboratory courses demonstrated

Chem. 252 (Advanced Organic Chemistry): Three terms

Chem. 251 (Introductory Organic Chemistry): Two terms

Chem. 111 (General Chemistry): One term

Involved in a laboratory development program to introduce new experiments for undergraduate labs: One

term.

April 2002- September 2002

Research Associate (term position)

Dept. of Pharmacy and Nutrition, University of Saskatchewan, Canada

Worked on a project entitled "Synthesis and Structure-Activity relationship study of cytotoxic N-

substituted 3,5-Bis (arylidene)-4-piperidone analogs" under the supervision of Professor J. R. Dimmock.

May 1996- Aug. 1997

Senior Research Fellow

National Chemical Laboratory, Pune, India

Involved in a project entitled – “A practical method for the synthesis of Artemisinin: A potential anti-

malarial drug” in the Division of Organic Chemistry Technology, under the supervision of Dr. T.

Ravindranathan and Dr. S. P. Chavan.

Jan. 1996 – April 1996

Lecturer

Modern College, Pune, India

Organic Chemistry (undergraduate level)

Sept. 1994 – Dec. 1995

Project Assistant

Dr. Reddy’s Research Foundation, Hydrabad, India

Worked on project entitled “Synthesis of Glycosidase inhibitors” under the supervision of Dr. B. B.

Lohray.

Aug. 1993 – Sept. 1994

Project Assistant

National Chemical Laboratory, Pune, India

Worked on a project entitled “Rational strategies for new drug discovery and treatment of AIDS” under

guidance of Dr. B. B. Lohray.

REFERENCES

Professor Michael Jung

Chair Teaching Committee

Department of Chemistry and Biochemistry

University of California Los Angeles (UCLA)

607 Charles Young Drive

3077 Young Hall

Box 951569

CA 90095

Phone: 1-310-***-**** e.mail:****@****.****.***

Professor Steve Hardinger

Senior Lecturer and Instructional Division Liaison

Department of Chemistry and Biochemistry

University of California Los Angeles (UCLA)

607 Charles Young Drive

3077 Young Hall

Box 951569

CA 90095

Phone: 1-310-***-**** e.mail:*******@****.****.***

Professor David Leigh

[Post-Doc. Supervisor]

School of Chemistry

University of Edinburgh

The King’s Buildings,

Edinburgh, EH9 3JJ

United Kingdom

Phone: 044-131-650-4721 e.mail: *****.*****@**.**.**

Contact this candidate