Development Manufacturing
Resume:
Aditi Sood
Framingham, MA-01702
Phone: 347-***-**** e-mail: *************@*****.***
Research Experience and Skills:
• Hands-on experience of 2 years with Dissolution apparatus I and II, DSC, HPLC, pH meter,
UV and Fluorescence spectrophotometer, colorimeter and Zetasizer Nano (DLS).
• Competent with molecular biology techniques like cell culture techniques, aseptic techniques,
ELISA, cell cytotoxicity (MTT), cell uptake and internalization, drug response studies in
cancer cell lines (M21 cell line).
• Experience in using laboratory equipment like microscope, autoclave and cell incubators
under aseptic conditions
• Worked on the novel drug delivery system of very low aqueous soluble anticancer drug (CPT)
using the mesoporous silica particles as carrier. The delivery system was evaluated for the
encapsulation efficiencies, adsorption affinities and drug release from the drug delivery
system.
• Acquired significant knowledge and working experience related to the physicochemical
characterization of small molecules including, equilibrium hydrolysis, pKa determination,
intrinsic and apparent solubility studies, solid state characterization and development of
various pharmaceutical analytical methods.
• Experience with a range of dosage forms, including liquids, solids and oral and controlled
release as well as formulation development experience for poorly soluble compounds.
• Reliable technical skills in a number of pharmaceutical unit operation and processes that include Fluid
bed dryer, Blenders, Granulation, Tableting and Coating Equipments etc.
• Experience with analytical techniques XRD, polarimeter, KF, near IR and Raman
spectroscopy.
• Computer skills and experience in scientific writing and documentation and hands on experience on
computer software such as Microsoft Solver, Power Point, Excel and MS-office.
• Worked on multiple projects with inter-department collaboration, writing reports, SOP's and
protocols.
• cGMP guidelines proficient and statistical analysis.
• Excellent writing and oral communication skills.
• Experience in human handling of animals (mouse and frog).
• Ability to work effectively and comfortably in a multi disciplinary team under defined timelines.
Education:
Masters in Industrial Pharmacy (September 2008 – Mar 2011)
Arnold & Marie Schwarz College of Pharmacy, Long Island University
Brooklyn, NY-11201
Bachelors in Pharmacy (August 2003 – June 2007)
Punjab Technical University,
Punjab, INDIA
Experience:
• Thesis: Preformulation and formulation studies of camptothecin (Jan. 2009 - Mar. 2011)
Work Summary
o The pH-dependent spectral alterations of CPT at acidic pH.
o Development and validation of analytical techniques (HPLC, UV and Fluorescence
spectrophotometery) used in formulation development of camptothecin.
o Preformulation studies including pKa determination, and pH-dependent solubilities
of CPT in acidic media.
o Equilibrium hydrolysis study was performed at various pH using PBS buffer.
o Loading and affinity studies of camptothecin with MCM-41 in aqueous acidic
solutions.
o CPT release kinetics studies from CPT loaded MCM 41 particles were carried out in
both simulated gastric and intestinal fluid in order to develop an effective delivery
system
• Graduate Assistant (Jan. 2009 – Sept. 2010).
Long Island University, NY
Work summary
Setting up the industrial pharmacy lab and assisting graduate students operating various manufacturing
equipment such as tablet presses, fluid bed coaters/dryers, mixers, powder blenders, and granulators.
Supervising the pharmaceutics and compounding labs for PharmD students aiming to learn and practice
compounding techniques toward preparation of their state board’s examination.
Responsibilities successfully completed included inventory management, housekeeping, lab prep and
monitoring of students during active formulation sessions
• Trainee in Production department, (Cipla Ltd., India) (Jun.-2007 to Aug-.2007).
Work Summary
o Manufactured formulations with multiple concentrations of tablets and liquid
formulations,
o Worked under GLP and GMP regulations and provided samples of manufactured
formulations for chemical analysis.
o Efficiently operated and calibrated lab equipment.
o Accounted all tests article/control articles including the procurement, documentation,
dispensing, and inventory.
o Performed pharmaceutical calculations and prepared documents and inventories for
the clinical formulation.
o Performed in process data audits of batch records and completed manufacturing
procedures generated by peers and subordinates.
o Prepared batch records with moderate supervision.
Graduate Course-work:
Seminar in Pharmaceutics Methods of Pharmaceutical Analysis
Physical Chemistry I Biopharmaceutics/Pharmacokinetics
Basic Pharmaceutics Calculus I
Advanced Physical Pharmacy I Cosmetic/Dermatological Formulations and Technology I
Industrial Pharmacy I Industrial Pharmacy II
Publication and Presentations:
Sood, A., Thakur, R., and Savva, M., “The loading and release kinetics studies of camptothecin
analogues (CPT& SN38) with mesoporous silica particles (MCM-41), “ under submission”.
Sood, A., Thakur, R., and Savva, M., “Camptothecin (CPT) loading and affinity studies with
mesoporous silica particles (MCM-41).” AAPS Annual Meeting and Exposition, New Orleans,
Louisiana, 2010.
“Anti-inflammatory study: A glance” at Punjab Technical University.
“Various new equipment, techniques and evaluation methods used in tablet manufacturing” at
Punjab Technical University.
“Good Laboratory Practice guidelines” at Cipla Ltd., Nalagarh, Himachal Pradesh.
Honors:
• Inducted in the Rho Chi Society for excellence in Academics (2010).
• Obtained bronze medal in Punjab Technical University in Bachelor of pharmacy.
• Awarded Scholarship in of Bachelor of Pharmacy for achieving academic excellence.
Work Status: Permanent resident (Green card holder)
Reference: Available on request.
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