SRILAXMI NERELLA
Phone: 707-***-**** ***, W Franklin St,
E-mail: ********.*******@*****.*** 1711, Richmond, VA-
23220
Objective:
Seeking a position in a stimulating work environment, that encourages
continuous learning and provides exposure to new ideas conducive to
personal and professional growth.
Education:
Masters in Bioinformatics, The University of Texas at El Paso (UTEP)
GPA 3.5/4.0
Masters in Biotechnology, Osmania University College for Women, India.
Bachelors in Genetics, Osmania University College for Women, India.
Technical Skills
Computational ABI SOLiD Bioscope, Bowtie, VectorNTI, TMeV, NCBI tools,
tools/software ExPASy, SMART, Phylogeny construction, microarray,
proteomics and genomic data analysis
Statistical tools MINITAB, SAS
Database Oracle, MySQL, HTML, JAVASCRIPT
Operating Systems UNIX, Windows95/98/XP/ 7/Vista, LINUX
Programming Perl, Java, C, C++ using MPI (Message Passing Interface),
Shell scripting(BASH), R
Office applications Microsoft Power Point, Excel, Access & Word
Professional Experience:
Research Assistant: August '10 - present
Virginia Commonwealth University, Richmond, Virginia
Major Project: Whole genome profiling to detect Schizophrenia methylation
markers
. Analysis of genome-wide biological datasets using next-generation
sequencing (ABI SOLiD Bioscope platform) of genomes and methylomes
(1575 human samples). The pipeline includes alignment of sequenced
reads against the reference genome, applying quality control
techniques, calculating CpG coverage estimates and bioinformatics
genome annotation and to determine the potential disease biomarkers
based on the methylation status of the CpG sites covered across the
samples.
Software: ABI SOLiD Bioscope, Bowtie
Programming: Perl, BASH, UNIX commands, parallel computing
Bioinformatics Intern: May-July'10
Virginia Commonwealth University, Richmond, Virginia
. Analyzed sequencing data of Methicillin-resistant Staphylococcus
aureus [MRSA] to investigate about the adaptive changes that it will
undergo to get homogeneous resistance.
. Handled large datasets such as genomic, proteomics data and
microarrays data on Tmev, Ramhorn Array Database (RAD)
Software/Databases: VectorNTI (Invitrogen), TMeV, RAD
Graduate Research Assistant: June'09-May'10
The University of Texas at El Paso, El Paso, Texas
. Computationally studied the sequences from protein spots obtained
through LC/MS
. Analyzed the proteins for Calcium binding domains using various tools
and databases (NCBI, InterProScan, SMART, and Swiss Prot) and
continued with phylogenetic studies of the proteins. Predicted the
proteins with the domains based on the results obtained.
. Made an attempt to prove the results obtained using cloning and
expression protocols.
Graduate Research Assistant: Aug'08 - May'09
The University of Texas at El Paso, El Paso, Texas
. Gathered information about distinguishing features, molecular markers,
and diagnostic techniques for lung and breast cancers.
. Studied various algorithms to improvise the quality of cancer images.
Academic Courses
Bioinformatics: Introduction to Bioinformatics I (Perl), Introduction to
Bioinformatics II (Perl)
Statistics: Special Topics (Independent Study) in Biostatistics, Post
Genomic Analysis (Minitab, R).
Computer Science: Intro to Computer Science (Java), Elementary Data
Structures/Algorithms in Java, Data Structures in Java, Database Management
(PHP, MySQL, Oracle, HTML, JAVASCRIPT), Parallel and Concurrent Programming
(C, C++, MPI)
Projects/Seminars:
1) Multiple Sequence Alignment of genomic sequences on multiple
processors Spring 2010
Wrote a C++ program using MPI to divide the given multiple sequences
into small parts at the root processor, sent them to the other processors
where they were aligned at the last row of the processors, induction of
gaps into the sequences to get good alignment, refined the alignment and
send it to the root processor, joined all the individual parts to get the
final best multiple sequence alignment.
2) CS 4342 (Database Management)
Fall 2009
. Created a database on 'Export, Return or Drawback of merchandise' (CBP
form -7553)
. Technical Environment: HTML, PHP, JavaScript MySQL
3) Active participant in NMBIS Symposium 2009 and 2010 conducted by
National Center for Genomic Resources, Santa Fe, NM.
4) Participated in "Entrepreneurship Awareness camp in Biotechnology"
conducted by ICRISAT and "Biologiks" the lecture workshop in Modern biology
organized by Indian Academy of Sciences, India.
Awards/Activities:
. Presented a research poster at Santa Fe in NM-IMBRE Bioinformatics and
Sequencing Core at NCGR 2010.
. Presented a research poster in 'American Society for Microbiology Rio
Grande Branch 2010 Annual Meeting'.
. Selected for "Best Research Content Poster Award"for Annual Poster
Sessions 2009, Bioinformatics Program, UTEP
. Acted as Vice-President for association of Bioinformatics students, UTEP.
. Organized 'International Food Festival', Colloquiums and poster
presentations at UTEP.
. Received "Participation Award" for Cancer research work with Dr.Wei Qian,
UTEP.
. Active member in National Service Scheme, India.
. Received a 'Gold Medal' for securing highest aggregate marks in high
school, India.
Personal Skills:
. Proficiency in Statistical and Bioinformatics techniques and protocols.
. Possess excellent communication skills.
. Hard working, sincere and having an aptitude for problem solving.
. Willingness to put best efforts in to achieve targets and objectives.
. Quick learner.
. Ability to work effectively both as an individual and as part of a team.
. Optimistic