Engineering Engineer

Richard Allen Lasher

*** ******** **** ** • Farmington, UT 84025

Phone 360-***-**** • E-mail ab9xnp@r.postjobfree.com

Education

Ph.D. in Bioengineering 12/2011

University of Utah, GPA: 4.0 Salt Lake City, UT

B.S. in Bioengineering with a minor in Spanish 05/2006

Washington State University, magna cum laude, GPA: 3.81 Pullman, WA

Related Experience

Senior Design Engineer 02/2012 to Present

Fresenius Medical Care, Inc. Ogden, UT

Provide innovative solutions for disposable devices used in renal therapy

Coordinate major design projects from concept through product release under FDA Design

Control and ISO regulations

Manage project resources and timelines to successfully meet project goals and milestones

Apply fundamentals and engineering principles to provide design solutions to complex,

multi-disciplinary problems

Create engineering specifications including 3D CAD models (SolidWorks®), detailed

drawings, inspection documents, and test methods

Develop custom test fixtures and methods to characterize and challenge product performance

Write test protocols and engineering studies to demonstrate product feasibility

Interface with third parties to prototype and manufacture subcomponents

Utilize injection molding, thermoforming, ultrasonic welding, and solvent bonding

techniques

Manage and train engineering technicians

Develop and deliver presentations to the team and upper management

Design Engineer 07/2008 to 02/2012

Catheter Connections, Inc. Salt Lake City, UT

Key member of a fast paced engineering team that designed and developed a disinfecting

device for infusion therapy

Developed multiple product configurations from concept through product release in

accordance with the FDA design control process

Created models and drawings using SolidWorks® for product and tooling specifications

Planned and performed characterization, verification, and validation testing

Designed test methods and fixtures for various stages of product testing and manufacturing

Developed process solutions, manufacturing procedures, device assembly methods and

manufacturing documents for pilot and full-scale production

Planned and executed process validation (IQ, OQ, PQ)

Traveled to China to implement multiple production lines

Page 1 of 5

Developed packaging validation plan in accordance with ISO standards to obtain CE marking

Managed and trained engineering interns for device testing and production

Graduate Research Assistant 08/2007 to 12/2011

University of Utah Salt Lake City, UT

Developed innovative techniques to produce and characterize cardiac tissue in vitro

Designed and constructed a novel bioreactor using 3D CAD software (Solidworks®) and

prototyping technologies (mill, lathe, CNC, lithography, 3D printing)

Performed various animal studies and familiar with surgical procedures and animal protocols

Applied immunofluorescent labeling and developed confocal imaging techniques to

characterize the cardiac microstructure

Managed a team of undergraduates in research activities

Prepared grants and manuscripts for publication

Research Associate in Biomechanics 05/2003 to 08/2007

Washington State University Pullman, WA

Responsible as primary staff coordinator for management of multiple lab projects

Created a biomechanical model of human neck using Magnetic Resonance Imaging (MRI)

and 3D rendering software

Utilized motion analysis and electromyograms (EMG) to investigate the response of the head

and neck to applied perturbations

Used sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) to characterize

tissue level changes that occur in hibernating bears

Research Assistant in Genetics 07/2003 to 06/2006

United States Department of Agriculture (USDA) Pullman, WA

Mapped Quantitative Trait Loci (QTLs) for cold tolerance in wheat

Extracted plant genomic DNA and performed Polymerase Chain Reaction (PCR)

Performed polyacrylamide gel electrophoresis using LI-COR® system

Teaching Assistant for Bioengineering Lab 01/2005 to 05/2005

Washington State University Pullman, WA

Taught fundamentals of MATLAB programming

Evaluated homework and student progress

Journal Publications

Schwab BC, Seemann G, Lasher RA, Torres NS, Wulfers EM, Arp M, Carruth ED, Bridge JH, Sachse

FB. Quantitative Analysis of Cardiac Tissue including Fibroblasts Using Three-Dimensional Confocal

Microscopy and Image Reconstruction: Towards a Basis for Electrophysiological Modeling. IEEE

Transaction on Medical Imaging, vol. 32, pp. 862-72, 2013.

Lasher RA, Pahnke AQ, Johnson JM, Sachse FB, Hitchcock RW. Electrical Stimulation Directs

Engineered Cardiac Tissue to an Age-Matched Native Phenotype. Journal of Tissue Engineering, vol.

3, 2012.

Page 2 of 5

Lackey DP, Carruth ED, Lasher RA, Boenisch J, Sachse FB, Hitchcock RW. Three-Dimensional

Modeling and Quantitative Analysis of Gap Junction Distributions in Cardiac Tissue. Annals of

Biomedical Engineering, vol. 39, pp. 2683-94, 2011.

Dittami GM, Rajguru SM, Lasher RA, Hitchcock RW, Rabbitt RD. Intracellular calcium transients

evoked by pulsed infrared radiation in neonatal cardiomyocytes. The Journal of Physiology, vol. 15,

pp. 1295-306, 2011.

Kennedy JP, Lasher RA, Solomon DD, Hitchcock RW. Disinfection of Male Luer Style Connectors for

Prevention of Catheter Related Bloodstream Infections Using an Isopropyl Alcohol Dispensing Cap.

ASME Medical Devices, 2010.

Lasher RA, Wolchok JC, Parikh MK, Kennedy JP, Hitchcock RW. Design and Characterization of a

Modified T-Flask Bioreactor for Continuous Monitoring of Engineered Tissue Stiffness.

Biotechnology Progress. vol. 26, pp. 857-64, 2010.

Kennedy JP, McCandless SP, Lasher RA, Hitchcock RW. The Mechanically Enhanced Phase

Separation of Sprayed Polyurethane Scaffolds and Their Effect on the Alignment of Fibroblasts.

Biomaterials, vol. 31, pp. 1126-32, 2010.

Lasher RA, Hitchcock RW, Sachse FB. Towards Modeling of Cardiac Micro-Structure With Catheter-

Based Confocal Microscopy: A Novel Approach for Dye Delivery and Tissue Characterization. IEEE

Transactions on Medical Imaging, vol. 28, pp. 1156-64, 2009.

Vasavada AN, Lasher RA, Meyer TE, Lin DC. “Defining and Evaluating Wrapping Surfaces for MRI-

derived Spinal Muscle Paths,” Journal of Biomechanics, vol. 41, pp. 1450-7, 2008.

Conference Proceedings

Lasher RA, Sachse FB, Hitchcock RW. 3D Architecture of Engineered Cardiac Tissue Revealed by

Confocal Microscopy. National Heart Lung and Blood Institute (NHLBI) Symposium on

Cardiovascular Regenerative Medicine. Bethesda, MD, 2011.

Lasher RA, Sachse FB, Hitchcock RW. Utilizing Electrical Stimulation to Direct the Development of

Engineered Cardiac Tissue. 7th Annual Utah Biomedical Engineering Conference. Salt Lake City, UT,

2011.

Carruth ED, Lasher RA, Schwab B, Sachse FB, Hitchcock RW. Three-Dimensional Modeling and

Quantitative Analysis of Protein Distributions in Cardiac Tissue. 7th Annual Utah Biomedical

Engineering Conference. Salt Lake City, UT, 2011.

Arp M, Lasher RA, Seemann G, Dossel O, Hitchcock RW, Sachse FB. Imaging the Micro-

structure of Cardiac Tissue by Fluorescence Confocal Microscopy based on Quadruple

Labeling. Biomedizinische Technik (BMT). Freiburg, Germany, 2011.

Sachse FB, Arp M, Lasher RA, Seemann G, Hitchcock RW. Micro-structural basis of

mathematical modeling of cardiac tissue. ICIAM, Vancouver, Canada, 2011.

Lasher RA, Sachse FB, Hitchcock RW. Development and Characterization of 3D Cardiac Tissue

Models In-Vitro. 6th Annual Mountain West Biomedical Engineering Conference. Park City, UT,

2010.

Dittami GM, Rajguru SM, Lasher RA, Hitchcock RW, Dharia SS, Rabbitt RD. Pulsed Infrared (IR)

Radiation Evoked Calcium Release in Neonatal Cardiac Myocytes. 6 th Annual Mountain West

Biomedical Engineering Conference. Park City, UT, 2010.

Page 3 of 5

Huang C, Lasher RA, Kaza AK, Hitchcock RW, Sachse FB. A Preparation for Imaging of Cardiac

Tissue Using Fiber-Optics Confocal Microscopy. 6th Annual Mountain West Biomedical Engineering

Conference. Park City, UT, 2010.

Carruth ED, Lackey DP, Lasher RA, Hitchcock RW, Sachse FB. Confocal Microscopy-Based

Characterization of the 3D Spatial Distribution of Connexin43 in Left Ventricular Cardiac Tissue. 6 th

Annual Mountain West Biomedical Engineering Conference. Park City, UT, 2010.

Dittami GM, Rajguru SM, Lasher RA, Hitchcock RW, Dharia SS, Rabbitt RD. Pulsed Infrared (IR)

Radiation Evoked Calcium Release in Neonatal Cardiac Myocytes. Biomedical Engineering Society.

Austin, TX, 2010.

Lasher RA, Parikh MK, Sachse FB, Hitchcock RW. An Electro-Mechanical Bioreactor for

Engineering Diseased Cardiac Tissue Models. Society for Biomaterials. Seattle, WA, 2010.

Kennedy JP, Lasher RA, Solomon DD, Hitchcock RW. Disinfection of Male Luer Style Connectors

for Prevention of Catheter Related Bloodstream Infections Using an Isopropyl Alcohol Dispensing

Cap. Design of Medical Devices Conference. Minneapolis, MN, 2010.

Lasher RA, Sachse FB, Hitchcock RW. Confocal Microscopy and Imaging Processing Techniques for

Online Monitoring of Engineered Tissue. ASME 2009 Summer Bioengineering Conference. Lake

Tahoe, CA, 2009.

Lasher RA, Parikh MK, Hitchcock RW. Continuous Tissue Stiffness Monitoring in a Modified T-

Flask Bioreactor. 5th Annual Mountain West Biomedical Engineering Conference. Park City, UT,

2009.

Lackey DP, Lasher RA, Hitchcock RW, Sachse FB. Imaging of Connexin-43 Distribution in Cardiac

Tissue: Experimental Protocol, Data Analysis and Preliminary Results. 5 th Annual Mountain West

Biomedical Engineering Conference. Park City, UT, 2009.

Lasher RA, Hitchcock RW, Sachse FB. Towards In Vivo Characterization of Cardiac Tissue with

Catheter-Based Confocal Microscopy. National Biomedical Computational Resource. San Diego, CA,

2009.

Lasher RA, Parikh MK, Hitchcock RW. A Novel Bioreactor for Continuous Monitoring of Force-

Displacement. ASME 2009 Summer Bioengineering Conference. Lake Tahoe, CA, 2009.

Lasher RA, Sachse FB, Hitchcock RW. Towards Online Monitoring of Engineered Tissue Using

Confocal Microscopy and Image Processing. Society for Biomaterials. San Antonio, TX, 2009.

Lasher RA, Hitchcock RW, Sachse FB. A Novel In Vivo Method for Local Dye Delivery with

Application in Confocal Microscopy of Cardiac Tissue. 4th Annual Mountain West Biomedical

Engineering Conference. Park City, UT, 2008.

Vasavada A, Lasher RA, Meyer T. Criteria for Wrapping Surface Parameters for Spinal

Muscles. American Society of Biomechanics. Stanford, CA, 2007.

Zheng L, Rico L, Lasher RA, Vasavada A. Biomechanical Neck Model Based on the Visible

Human Female. American Society of Biomechanics. Stanford, CA, 2007.

Lasher RA, Meyer T, Vasavada A. Development and Validation of Curved Muscle Paths in a

Neck Model. Northwest Biomechanics Symposium. Vancouver, BC, Canada, 2006.

Lasher RA, Meyer T, Gavin P, Vasavada, A. MRI-Based Geometry of Neck Muscles for

Biomechanical Models. American Society of Biomechanics, Portland, OR, 2004.

Patents

Page 4 of 5

Hitchcock R, Bandis S, Solomon D, Ferguson M, Kennedy J, Lasher RA. Disinfectant Caps and

Systems and Associated Methods. Application # 61/265,216

Page 5 of 5

Contact this candidate