BEN L. CHEN
**** ********* ****,******, ** *****
Cell phone: 504-***-****, E-mail: **********@*****.***
Education:
**** **** ** ****** ********** School of Public Health and Tropical Medicine.
2006 71 credits in Cellular& Molecular Biology at Tulane Uni. College
1973-1977 M.D. at Southeast University School of Medicine in Nanking, P.R. China
Experience:
2007-2012 Ochsner Hospital/Basic Science/Molecular Biology--Research Associate and Lab.
Technical Director.
1991-2006 Tulane University School of Medicine/Peptide--- Research.
Shanghai Seaman’s Hospital Surgical Department Surgeon.
1977-1990
Shanghai 6th People’s Hospital Surgical Department Training-- Surgeon
1978-1979
Shanghai Seaman’s Hospital Surgical Department--Chief Resident
1987-1989
Biology Skills:
Small animal studies using anesthetized mice/rats
Intravenous injection and arterial catherization(such as: mice carotid artery)
Intracardial perfusion( such as mice jargular vein chronic perfusion)
Special implant DSI different Telemeter to mice, mice and rats organ transplantation (such as kidney,
Liver and heart) and Mice tumor growth
Working on different size and animal model depending on protocol (such as chronic fistula on
stomach, esophagus perfusion, duodenum perfusion to measure amylase secretion and using different
ways to perfusion the drug
Tissue sectioning and sampling and generation of animal models according to protocols.
Establishing human cancer in nude mice for studying of peptide
Participating in establishing cell cultures and cell line, PCR, RT-PCR, SEQUENCE, Southern
Blot(gene typing), Western Blot, DNA, RNA, Protein Isolate. ELISA, Plasma construct (coloning)
and cell transfer. Large Scale and Minipreps, Flow cytometer
Immunohistochemistry study
Routine analytical biochemistry studies including HPLC. RIA.GC. fluorescence.
Using computer programs for analysis and calculation of data, tabulate statistical results, and
calculate ED50
Environmental Health Science Skill:
Epidemiology and Biostatistics study
Air sampling and analysis
Infection disease control study.
Computer Skills:
Microsoft Office, Photoshop. SAS. GraphPad Prism. Database Management, VB program, Orecal
programming,.
Publication:
1. Coy DH. Rossowski WJ. Cheng BL . Taylor JE.
Structural requirements at the N-terminus of urotensin II octapeptides.
Peptides. 2002 Dec:23(12):2259-64.
PMID: 12535707
2. Rossowski WJ. Cheng BL. Taylor JE. Datta R. Coy DH.
Human urotensin II-induced aorta ring contractions are mediated by protein kinase C. tyrosine kinases
and Rho-kinase: inhibition by somatostatin receptor antagonists.
Eur J Pharmacol. 2002 Mar 8:438(3): 159-70
PMID: 11909607
3. Rossowski WJ. Cheng BL. Jiang NY. Coy DH.
Examination of somatostatin involvement in the inhibitory action of GIP, GLP-1, amylin and
adrenomedullin on gastric acid release using a new SRIF antagonist analogue.
Br J Pharmacol. 1998 Nov:125(5): 1081-7.
PMID: 9846648
4. Coy DH. Mungan Z. Rossowski WJ. Cheng BL. Lin JT. Mrozinski JE Jr. Jensen RT.
Development of a potent bombesin receptor antagonist with prolonged in vivo inhibitory activity on
bombesin-stimulated amylase and protein release in the rat.
Peptides. 1992 Jul-Aug:13(4):775-81.
PMID: 1279632
5. K. M. Redding, B. L. Chen, A. Singh, R. N. Re, L. G. Navar, D. M. Seth, C. D. Sigmund, W. W. Tang,
and J. L. Cook
Transgenic mice expressing an intracellular fluorescent fusion of angiotensin II demonstrate renal
thrombotic microangiopathy and elevated blood pressure
References:
David H. Coy, Ph.D.
Professor and Head
Peptide Research Laboratories
1430 Tulane Ave., SL-12, New Orleans, LA. 70112-2699
Tel 504-***-****
Richard N. Re, M.D.
Scientific Director
***@*******.***
Recommendation Letter Available upon Request.