Design Medical

Amit Kumar

****, *********

oaks avenue,

Apt j, Dallas, TX-75235.

******@*****.***

Objective

A research and development position that emphasizes

creativity in new instrumentation

for analyzing biologically important materials.

Summary

. Synthesis and evaluation of PET and SPECT agents for early detection

of cancer and diabetes. Radio synthesis of PET and SPECT agents for

early detection of cancer and diabetes.

. Design and synthesis of water soluble ligand to aid copper-catalyzed

azide-alkyne cycloaddition reaction

. Design and synthesis of water soluble "click" activated fluorogenic

probes for use in bio conjugation

. Design and synthesis of multi-functionalized molecules

. Design and synthesis of linkers azide and alkyne terminated

biocompatible linkers and their attachment to peptides, proteins

fluorescent molecules, dendrimers and other biologically relevant

molecules

. Design and synthesis of molecules containing fluorinated chains

. Modification of dendrimers for biocompatibility

. Synthesis polymerized liposome and their modification. Extensive

experience in various separation, purification, and characterization

techniques.

Education

Postdoctoral Researcher (2011-Present)

University of Texas Southwestern Medical Center

Department of Radiology

Advisor: Dr. Xiankai Sun

Ph.D. in Chemistry (2003-2010)

Department of Chemistry, University of Houston, Houston, USA.

Dissertation title: Copper-catalyzed Azide-alkyne Cycloaddition Reaction

for Bio conjugation

Advisor: Dr. Chengzhi Cai

M.Sc. in Chemistry (2001-2003)

Department of Chemistry, Indian Institute of Technology, Bombay,

Mumbai, India.

Thesis title: Tertiary Phosphines and their Reactivities

Advisor: Dr. M. S. Balakrishna

B.Sc. in Chemistry (1998-2001)

Banaras Hindu University, Varanasi, India.

Research Experience

Postdoctoral Researcher- Department of Radiology, U. T. Southwestern

Medical Center

Advisor: Dr. Xiankai Sun (January 2011 - Present)

. Synthesis of PET agents for imaging of cancer and diabetes

Postdoctoral Researcher- Department of Chemistry, University of Houston,

Houston,TX.

Advisor: Dr. Chengzhi Cai (August 2010 - December 2010)

. Design and synthesis of multi-functionalized molecules

Ph.D. Student- Department of Chemistry, University of Houston,

Houston, TX.

Advisor: Dr. Chengzhi Cai (August 2003 - August 2010 )

. Synthesis of triazole based ligands for assisting copper-catalyzed

azide-alkyne cycloaddition reaction

. Optimization of copper-catalyzed azide-alkyne cycloaddition reaction

for aerobic as well as anaerobic conditions for bioconjugation

utilizing triazole-based ligands

. Synthesis of alkynyl terminated polymerized liposomes

. Surface modification of polymerized liposome via copper-catalyzed

azide-alkyne cycloaddition reaction

. Optimization of the composition of targeting and imaging agents on

periphery of polymerized liposomes

. Synthesis of carboxyl terminated polymerized liposome and its

subsequent modification with truncated antimicrobial peptide (IG-25)

via electrostatic, carbodiimide and copper assisted "click" reaction

M.Sc. Student- Department of Chemistry, Indian Institute of Technology,

Bombay, Mumbai, India.

Advisor: Dr. M. S. Balakrishna (June 2001- May 2003)

. Synthesis and characterization of tertiary phosphine based ligands and

their transition metal complexes.

Skills

. Synthesis

. Radio Synthesis

. Characterization

* NMR, Mass Spectroscopy, IR, UV, HPLC, Radio TLC, Gamma Counter,

PET, SPECT,

. Animal Handling

. Bio distribution

. Pharmacokinetics

Patent

Cai, Chengzhi; Qin, Guoting; Kumar Amit. Compositions and methods for

making and using multifunctional polymerized liposomes. U.S. Pat. Appl.

Publ. (2009),14 pp. CODEN:USXXCO US 200-***-**** A1 20090625

Publications

. Full List of '12 publications' and '3 poster publications' is

attached.

References

. Complete list of 3 References are attached.

Contact this candidate