Supervisor Assistant
Resume:
JENNIFER R. DAVIS
** ******* ******, ********** ** 02906
**************@*****.***
OBJECTIVE
Ambitious young professional with expertise in biochemistry and molecular biology seeks position in an
innovative research setting
EDUCATION
Brown University, Providence, RI, Aug 2008 – March 2013
Ph.D. Molecular Pharmacology and Physiology
GPA 4.0
Doctoral Thesis Title: Genetic, Biochemical and Biophysical Investigations of
Lignocellulose Degradation in Actinobacteria for Bioenergy Applications
Clark University, Worcester, MA, Aug 2004 – May 2008
B.A. Biochemistry and Molecular Biology
GPA 3.98
HONORS AND AWARDS
NSF Graduate Research Fellowship, 2010 – present
Sigma Xi Honor Society, Brown University, 2011
Pharmacia Fellow, Brown University, 2008
Summa cum laude, Clark University, 2008
Phi Beta Kappa, Clark University, 2008
American Institute of Chemists Award in Biochemistry, Clark University, 2008
Dean’s List First Academic Honors, Clark University, 2004 – 2008
TECHNICAL SKILLS
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molecular cloning isothermal titration calorimetry
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bioinformatic analyses colorimetric enzymatic assays
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genomic and plasmid DNA isolation circular dichroism
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RNA isolation SDS-PAGE
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site-directed mutagenesis western blot
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reverse-transcriptase PCR ELISA
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cultivation and genetic manipulation of electrophoretic mobility shift assays
E. coli and Streptomyces bacteria - protein crystallization
- large-scale protein expression and - mammalian and insect cell culture
purification - liquid scintillation counting
- FPLC and HPLC systems
Software experience with Sigma Plot, Image Quant, MicroCAL Origin, Pymol, BLAST analysis,
Integrated Microbial Genomes, Geneious, Gibbs Motif Sampler, Chemdraw, and Microsoft Office
RESEARCH EXPERIENCE
Graduate Research, Brown University, Providence, RI, Oct 2008-Present
Implemented and managed a new area of research in the laboratory investigating the
degradation of plant biomass by Streptomyces bacteria. Characterized the catabolism of
lignin, lignin-derived aromatics and cellulose using bioinformatic, genetic, biochemical
and biophysical techniques. Supervisor: Professor Jason Sello
Graduate Laboratory Rotation, Brown University, Providence, RI, July 2008-Oct 2008
Identified small molecule agonists and antagonists of the sigma-1 receptor by measuring
calcium release from sigma-1 overexpressing MCF-7 breast tumor cells. Supervisor:
Professor Wayne Bowen
Undergraduate Research Assistant, Clark University, Worcester, MA, Jan 2008-May 2008
Studied the catalytic center of tRNA nucleotidyltransferase using site-directed
mutagenesis. Supervisor: Professor David Thurlow
Research Intern, Pfizer, Groton, CT, Summer 2007
Assessed hepatic uptake clearance of drug leads in cryopreserved sandwich-cultured and
suspension hepatocytes. Supervisor: Dr. David Duignan
Research Project Assistant, Pfizer, Groton, CT, Summer 2006
Expressed human gamma-secretase in transfected Sf9 insect cells using recombinant
baculoviruses. Supervisor: Dr. David Auperin
Comparative Medicine Technician, Pfizer, Groton, CT, Summer 2005
Cared for animals in the vivarium and assisted veterinary staff with dosing . Supervisor:
Charles Dean
PUBLICATIONS
Davis, Jennifer R., Lynne A. Goodwin, Tanja Woyke, Hazuki Teshima, David Bruce, Chris
Detter, Roxanne Tapia, Shunsheng Han, James Han, Sam Pitluck, Matt Nolan, Natalia
Mikhailova, Miriam L. Land, and Jason K. Sello. Genome Sequence of Streptomyces
viridosporus ATCC 39115, a Lignin-Degrading Actinomycete. Journal of Bacteriology (in
preparation).
Davis, Jennifer R., Breann L. Brown, Rebecca Page, Jason K. Sello. Study of PcaV from
Streptomyces coelicolor Yields New Insights into Ligand-Responsive MarR Family Transcription
Factors. Nucleic Acids Research. (2013) 41(6):3888-3900.
Davis, Jennifer R., Lynne A. Goodwin, Tanja Woyke, Hazuki Teshima, David Bruce, Chris
Detter, Roxanne Tapia, Shunsheng Han, James Han, Sam Pitluck, Matt Nolan, Natalia
Mikhailova, Miriam L. Land, and Jason K. Sello. Genome Sequence of the Plant Biomass
Degrading Actinomycete, Amycolatopsis sp. ATCC 39116. Journal of Bacteriology. (2012)
194(9):2396-7.
Davis, Jennifer R. and Jason K. Sello. Regulation of Genes in Streptomyces Bacteria Required
for Catabolism of Lignin-Derived Aromatic Compounds. Applied Microbiology and
Biotechnology. (2010) 86:921–929.
PRESENTATIONS
Davis, Jennifer R., Breann L. Brown, Rebecca Page, Jason K. Sello. “Characterization of PcaV,
a Novel MarR Family Transcription Factor that Regulates Aromatic Catabolism in Streptomyces
Bacteria.” Boston Bacterial Meeting. Boston, MA. Jun 7-8, 2012
Davis, Jennifer R., Breann L. Brown, Rebecca Page, Jason K. Sello. “Catabolism of Lignin-
Derived Aromatic Compounds by Streptomyces Bacteria. 16th International Symposium on the
Biology of Actinomycetes. Puerto Vallarta, Mexico. Dec 11-15, 2011.
Davis, Jennifer R. and Sello, Jason K. “Catabolism of Plant Biomass by Streptomyces Bacteria.”
Genomics of Energy and Environment: 6th Annual DOE JGI User Meeting. San Francisco, CA.
March 22-24, 2011.
Davis, Jennifer R. and Sello, Jason K. “Catabolism of Plant Biomass by Streptomyces Bacteria.”
URI/UConn Biofuels Symposium. University of Rhode Island, RI. May 29, 2009.
Reeve, Jennifer, Yi-an B, E Kimoto, and D Duignan. “Comparison of Uptake Clearance in
Suspended and Sandwich-Cultured Cryopreserved Hepatocytes.” 16th North American Regional
ISSX Meeting. Baltimore, MD. October 18-22, 2009.
Reeve, Jennifer, Yi-an Bi, Veronica Zelesky, and David Duignan. “Hepatic Uptake in
Cryopreserved Human Hepatocytes – A Comparison between Suspension and Sandwich Culture
Models.” Annual Pfizer Summer Intern Symposium. Pfizer, Groton, CT. 2007
TEACHING EXPERIENCE
Undergraduate Mentorship, Brown University, June 2009 – present
Mentored and managed 6 undergraduate students in laboratory research.
Brown Environment Leadership Laboratory, Summer 2011, 2012
Integrated education with research through collaboration with local high school students
by performing hands-on experiments to isolate microorganisms from the soil.
Teaching Assistant, Brown University, Sept 2009 – Dec 2009
Instructed over 100 undergraduate students in an Introduction to Physiology course
through formal lecture and one-on-one mentoring
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