Project Medical
Resume:
Timothy Doody
********@*****.***
54A Brook Square, South Terrace, Cork
Profile
I am a dedicated and passionate scientist with extensive expertise in in
vitro and in vivo research, cancer models, gene delivery techniques,
medical devices and pulmonary drug delivery. I am an independent researcher
with strong leadership, analytical and communication skills.
Work Experience
September 2010 to Present
Researcher - Biopharmaceutics and Pharmacology, School of Pharmacy, UCC
Nanomedic project - Lead In vivo research element of a multi-centre
research project funded to develop nanoparticle based diagnositc and drug
delivery technology
. Develop murine and porcine models for pulmonary delivery of
nanoparticles using nebuliser technology and produce SOP's for
dissemination within coloborator groups
. Evaluation of delivery characteristics and immunologic properties of
nanoparticles both in vitro and in vivo. Main techniques involved
include HPLC, histology, ELISA, fluoresence and in vivo imaging
. Evaluation and reporting of data along with written and verbal
presentation both in house and to collaborators
. Administrate the budget for this project with responsibility for
purchasing and management of project including successfull awarding of
funding for project beyond initial year
Further to leading this project I am extensively involved in a number of
other projects:
. Develop microneedle technology for transdermal delivery specifically
targeting the lymphatic system
. Formulation of drugs and proteins
. in vitro testing of gold nanoparticles for siRNA delivery
. in vitro testing of novel polymer films for use in medical devices
. Establishment of cell culture model for bone regeneration studies
. Proposal and supervision of final year undergraduate pharmacy student
projects
October 2005 to September 2010 -
Researcher - Cork Cancer Research Centre
Research involved two multi-disciplinary collaborative projects with the
Tyndall National Institute and the Biopharmaceutics Lab, School of
Pharmacy, UCC
. Assess novel electrodes for the delivery of electric fields both in
vitro and in vivo for the purpose of electroporation
. Assess the efficacy of novel gene delivery vectors (poly-L-lysine and
modified cyclodextrins) for targeted delivery to tunour tisue and
develop suitable in vitro and in vivo test models
. Provide training to new students and technical staff on gene therapy
techniques
Other Work Experience
2006 to 2012 - Laboratory Demonstrator, Invigilator, Examiner - School of
Pharmacy, UCC, Cork
2008 to 2009 - Note taker and exam assistant - Disability Support Service,
South Lodge, UCC
Earlier Career:
Sept 2004 to Oct 2005 - Long Island Bar, Washington St., Cork
Summer 2004 - The Boiler House Restaurant, Distillery District, Toronto,
Canada
Summer 2003 - Palace Playland, Old Orchard beach, Maine, USA.
Education
2004
University College Cork
BSc (Biochemistry) - Overall result: Second Class Honours Grade 1
Final year Project Title: Site-directed Mutagenesis of the Hfe and LEA1
genes (Grade 1.1)
2000
Scoil Mhuire & Ide, Newcastle West, Co. Limerick
Leaving Certificate Overall Result: 510 points
Training and Educational Courses
FP7 and Grant Writing Workshop, UCC - Spring 2009
Course provided by Sean McCarthy, Hyperion Ltd
This course taught the essential skills required for grant writing.
Starting with identifying and targeting suitable grant calls, the course
progressed to cover: sources of new ideas, screening of ideas, converting
these ideas to workable proposals and seeking collaborations.
Advanced Imaging Technologies Course, UCD - March 2008
Course Provided by the Dublin Molecular Medicine Centre
This Course covered the most widely used technologies for in vitro, in vivo
and diagnostic research. These techniques included electron microscopy,
fluorescence and confocal microscopy, CT, MRI and PET scanning. The basic
principles of imaging, applications and current innovations and advances
were studied. A certificate of attendance was awarded.
LAST Ireland - Laboratory Animal Science and Training - January 2006
This is the Irish training program to be completed in order to meet the
legal and scientific requirements to carry out work in animal models.
Passed all modules and certified for the care and use of animals in
accordance with the legislative framework (both EU and Irish regulations).
Technical Skills
Extensive knowledge of: In vivo models, Cell culture, aseptic technique,
molecular biology techniques (cloning, SDM, plasmid purification), non-
viral gene delivery methods, flow cytometry, fluorescence microscopy,
immunostaining, histology, HPLC
Proficient at: Protein purification and western blotting, DNA/RNA
extraction, PCR
Presentations
"Improving electrochemotherapy using a novel minimally invasive delivery
system" - Microneedle Applications Workshop, Tyndall National Institute -
December 2008
"Medical Applications of Microneedles' - Public Lecture, School of
Medicine, UCC - May 2010
"Developing a murine model for in vivo assessment of pulmonary nanoparticle
delivery"- UKICRS Symposium, Birmingham, UK - May 2012
Publications
Verma NK, Crosbie-Staunton K, Satti A, Gallagher S, Ryan KB, Doody T,
McAtamney C, Macloughlin R, Galvin P, Burke CS, Volkov Y, Gun'ko YK.
Magnetic core-shell nanoparticles for drug delivery by nebulization. J
Nanobiotechnology. 2013 Jan 23;11(1):1.
K. Rahme, T. Doody, A.K. Jain, L. Chen, M. Morris, C. O'Driscoll,, J.D.
Holmes. Synthesis and Stabilisation of Gold Nanoparticles coated with
Poly(ethylene glycol) for siRNA Delivery Biomedical Engineering 1 (1) e-
issn 194*-****-****
J.B. Carey, F.E. Pearson, A. Vrdoljak, M.G. McGrath, A.M. Crean, P.T.
Walsh, T. Doody, C. O'Mahony, A.V.S. Hill, A.C. Moore.Microneedle Array
Design Determines the Induction of Protective Memory CD8+ T Cell Responses
Induced by a Recombinant Live Malaria Vaccine in Mice." PLoS ONE 6(7):
e22442 2011
Grants and Awards
Cancer Research Ireland - Awarded Oncology Scholar Travel Awards for travel
to ASGT conference 2007
Tyndall National Access Programme - Grant awarded to cover the costs for
the production and testing of novel microneedle electrodes (grant # NAP157)
- 2008
Hobbies, Interests and Achievements
. I was a member of the College of Medicine and Health Postgraduate
Committee 2010/11. Role involved developing educational and social
support systems for postgraduates students and developing
communication channels between students and the college
. I like to keep active by going to the gym, running and I am a member
of a tag rugby team.
References
Available on request
Contact this candidate