Quality Control Assurance

Hao Zhang, MLS (ASCP)

E-mail: ***************@*****.***

OBJECTIVES

• Medical Laboratory Scientist with ASCP certification, one year of Medical Technologist experience (microbiology) at Henry Ford Hospital (main campus) and bachelor's degree in Clinical Laboratory Science at Wayne State University. Searching for a medical technologist / research technician positions in the States.

• Excellent clinical laboratory and research skills, with commended performance conducting/analyzing laboratory assays and resolving complex clinical and instrument problems. Excellent computer (Words, Excel, Excess, Laboratory information systems) and communication skills (oral and writing).

• Accurate, reliable, diligent and focused on the timely, quality completion of all lab procedures. Work well under pressure and time constraints within high-volume environments.

PROFESSIONAL EXPERIENCE

10/2012- 08/2013

• Medical Technologist (Microbiology)

• Henry Ford Hospital, Detroit Michigan

Performing moderate and high complexity testing in microbiology, including tests ordering, specimens set-up. Analyzes, reviews, and reports gram stain and culture results and quality control results and takes remedial action when indicated. Performing full identification and susceptibility of the pathogens with VITEK machine. Ensures specimen integrity by adhering to the laboratory’s procedures for specimen handling and processing. Adheres to departmental policies and procedures to include departmental programs, quality control, quality assurance, and safety.

01/2012-06/2012

• CLS Clinical Rotation

• Henry Ford Hospital, MI (Main Campus)

I was trained in Chemistry, Hematology, Urine analysis, Blood Bank and Microbiology. Under general supervision, I performed routine and complex analytic procedures, on blood and/or other body fluids or specimens, involving manual techniques or the use of laboratory instruments and information systems, includingSiemens Dimension Vista, Siemens ADVIA Centaur CP immunoassay System, Beckman Coulter Unicel Dxc800 Synchron clinical System for chemsitry, iQ 200 system and AX-4280 for urine analysis, STA-R Evolution® Expert Hemostasis System for coagulation, and Coulter LH 750 for routine hematology.

09/2006- 08/2009

• Research Assistant (Cancer’s Chemoprovention and Radiation Research)

• Radiation Oncology Department, Wayne States University, MI

• Supervisor: Dr. Gilda Hillman

This study is to test combined modalities with radiation and natural products or radiation and gene/immunotherapy in animal tumor models and different cancer cell lines.

I performed surgical procedures in mice to implant tumors in different organs and tested experimental anti-cancer therapies using mouse models, irradiation of tumors, intratumoral gene therapy or systematic administration of natural products.

Other techniques includes: purification and quantification of plasmids, transfection of tumor cells with plasmids or adenoviral vectors; performance of Western blots to test for signal transduction molecules and use of kits for detection of phosphorylated signal molecules, electrophoretic mobility shift assay (EMSA) and imaging, confocal microscope imaging, data preparation for publish, routine lab maintainance.

10/2003-09/2005

• Clinical Cytogenetic

• Joint Sino-US Clinical & Molecular Laboratory, School of Public Health, Fudan University, China

• Sponsor: University of Colorado, Denver

• Supervisors: Dr. Richard D. Irons and Dr. Liming Bao

The purpose of this study is to investigate the dose-response relationship between benzene exposure and blood diseases in Shanghai workers and to characterize genetic polymorphisms that are associated with increased risk of developing benzene hematotoxicity.

My role in this study was the slides preparation and analysis of banded chromosomal. It was performed on un-stimulated BM cells following 24–72 h of culture. Chromosomes were prepared and G-banding after trypsin was performed according to standard techniques. Analysis was executed by karyotype and Fluorescent in situ hybridization (FISH).

06/2002-06/2003

• Clinical Pathology Diagnosis Training Fellowship

• Department of Pathology, Shanghai Cancer Hospital, Fudan University, China

I was trained in grossing and processing abnormal tissues in cancer patients to make clinical diagnosis by microscopic observations. The techniques included: dissection of fixed surgical specimen; slide preparation from paraffin block and frozen tissues; H&E and immunohistochemistry staining, pathological diagnosis under microscope.

11/1999-05/2002

• Resident

• Henan Occupational Disease Institute, China

CERTIFICATIONS AND MEMBERSHIPS

08/2012 Medical Technologist Scientist Certification of American Society for Clinical Pathology (MLS/ASCP)

10/2010- present Membership of American Society for Clinical Laboratory Science (ASCLS)

10/2010- present Membership of American Society for Clinical Pathology (ASCP)

08/2011- present Membership of Golden Key International Honour Society

06/2003 Graduate Certificate of Clinical Pathology Diagnosis Program,

Cancer Hospital, Fudan University, China

EDUCATIONS AND HONORS

09/2009- 06/2012 Wayne State University, MI Bachelor of Clinic Laboratory Science

06/2012 Wayne State University, MI 2012 CLS Magna Cum Laude

04/2010 Wayne State University, MI 2010 Chemistry Chair's Honor List

07/1994-06/1999 Henan Medical University, China Bachelor of Medicine

PUBLICATIONS

1. Raffoul JJ, Banerjee S, Singh-Gupta V, Knoll ZE, Fite A, Zhang H, Abrams J, Sarkar FH and Hillman GG. Downregulation of Apurinic/Apyrimidinic Endonuclease 1/Redox factor-1 (APE1/Ref-1) Expression by Soy Isoflavones Enhances Prostate Cancer Radiotherapy In Vitro and In Vivo. Cancer Res. 2007 Mar 1; 67(5):2141-9.

2. Singh-Gupta V, Zhang H, Banerjee S, Kong D, Raffoul JJ, Sarkar FH, Hillman GG. Radiation-induced HIF-1alpha cell survival pathway is inhibited by soy isoflavones in prostate cancer cells. Int J Cancer.2008 Sep 24.

3. Hillman GG, Singh-Gupta V, Zhang H, Al-Bashir AK, Katkuri Y, Li M, Yunker CK, Patel AD, Abrams J, Haacke EM. Dynamic contrast-enhanced magnetic resonance imaging of vascular changes induced by sunitinib in papillary renal cell carcinoma xenograft tumors. Neoplasia. 2009 Sep; 11(9):910-20.

4. Singh-Gupta V, Zhang H, Yunker CK, Ahmad Z, Zwier D, Sarkar FH, Hillman GG. Daidzein effect on hormone refractory prostate cancer in vitro and in vivo compared to genistein and soy extract: potentiation of radiotherapy. Pharm Res. 2010 Jun;27(6):1115-27. Epub 2010 Mar 23.

5. Hillman GG, Singh-Gupta V, Al-Bashir AK, Zhang H, Yunker CK, Patel AD, Sethi S, Abrams J, Haacke EM. Magnetic Resonance Imaging of Sunitinib-Induced Vascular Changes to Schedule Chemotherapy in Renal Cell Carcinoma Xenograft Tumors. Transl Oncol. 2010 Oct 1;3(5):293-306.

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