Nicholas R. Rhodes Ph.D. Page *
Nicholas R. Rhodes, Ph.D.
Post-Doctoral Research Assistant
Dept. of Chemistry and Biochemistry, Baylor University
***************@*****.***
www.linkedin.com/pub/nicholas-rhodes/2b/186/413/
EDUCATION
2011- 2013 Postdoctoral fellow, Baylor University (Bryan F. Shaw)
2007-2011 Ph.D., Chemistry, The University of Alabama (John B. Vincent)
2007 B.S., Chemistry, University of West Georgia
2004 B.S., Environmental Chemistry, University of West Georgia
EXPERIENCE
Post-doctoral research, Baylor University, Waco, TX 2011-2013
• Electrostatically inhibit the self-assembly of superoxide dismutase (SOD1) using
aspirin to increase the net negative charge
• Identified change in electrostatics of SOD1 by capillary electrophoresis (CE) and LC-
MS and monitored the self-assembly with fluorescence.
• Screen and developed small molecules for acetylating capability that electrostatically
inhibit the self-assembly of SOD1 into neurotoxic structures
Graduate research, The University of Alabama, Tuscaloosa, AL 2007-2011
• Performed homeostasis studies with mammalian cells ( Hep G2 and C2C12) to track
radioactive labeled chromium and iron on the cellular level
• Performed numerous studies of chromium with rats and mice: toxicity of compounds,
effect on insulin and glucose tolerance, absorption, and nutritionally essential.
• Synthesized inorganic chromium compounds
Laboratory Technician, Wayne Davis Concrete, Tallapoosa, GA 2005-2007
• Optimized and designed new concrete mixtures for better concrete strength while
cutting cost.
• Prepared job submittals to various contractors, architect, and engineering firms.
Reviewed job specs to identify what type of concrete mix was needed.
Nicholas R. Rhodes Ph.D. Page 2
PUBLICATIONS
1) Rhodes, N.R., Konovalova, T., Liang, Q., Cassady, C.J., Vincent J.B. Mass Spectrometric
and Spectroscopic Studies of the Nutritional Supplement Chromium(III) nicotinate. Biol.
Trace Elem. Res. 2009; 130 (2): 114-130.
2) Rhodes, N.R., McAdory, D., Love, S., Di Bona, K.R., Chen, Y., Ansorge, K., Hira, J.,
Kern, N., Lara, P., Rasco, J.F., Vincent, J.B. Urinary Chromium Loss Associated with
Diabetes is Offset by Increases in Absorption. J. Inorg. Biochem. 2010; 104: 790-797.
3) Di Bona, K.R., Love, S., Rhodes, N.R., McAdory, D., Sinha, S.H., Kern, N., Kent, J.,
Strickland, J., Wilson, A., Beaird, J.,Ramage, J., Rasco, J.F., Vincent. J.B. Chromium is
not an essential trace element for mammals: Effects of a “low-chromium” diet. J. Biol.
Inorg. Chem. 2011; 16: 381-390.
4) McAdory, D., Rhodes, N.R., Briggins, F., Bailey, M. M., Di Bona, K. R., Goodwin, C.,
Vincent, J. B., Rasco, J.F. Potential of Chromium(III) Picolinate for Reproductive or
Developmental Toxicity Following Exposure of Male CD-1 Mice Prior to Mating. Biol.
Trace Elem. Res. 2011; 143: 1666-1672.
5) Rhodes, N.R., LeBlan, P.A., Rasco, J.F., Vincent, J.B. Monocarboxylate Transporters Are
Not Responsible for Cr3+ Transport from Endosomes. Biol. Trace Elem. Res. 2012; 148:
409-414.
6) Staniek, H., Rhodes, N.R., Di Bona, K.R., Deng, G., Love, S., Pledger, L.A.,Blount, J.,
Gomberg, E., Grappe, F., Cernosek, C., Peoples, B., Rasco, J.F., Krejpcio, Z., Vincent,
J.B. Comparison of Tissue Metal Concentrations in Zucker Lean, Zucker Obese, and
Zucker Diabetic Fatty Rats and the Effects of Chromium Supplementation on Tissue Metal
Concentrations. Biol. Trace Elem. Res. 2013; 151: 373-383.
7) Rhodes, N. R., Belmore, K., Cassady, C. J., Vincent, J. B. Paramagnetic 19F NMR and
Electrospray Ionization Mass Spectrometric Studies of Substituted Pyridine Complexes of
Chromium(III): Models for Potential Use of 19F NMR to Probe Cr(III)-Nucleotide
Interaction. Polyhedron 2013; DOI 10.1016/j.poly.2013.03.002
8) Shi, Y., Rhodes, N.R., Kohn, T., Cook, N.P., Abdolvahabi, A., Mowery, R.A., Marti,
A.A., Shaw, B.F. Asparagine deamidation in wild-type SOD1 can mimic the biophysical
effects of mutations that cause amyotrophic lateral sclerosis. Proc Natl Acad Sci USA Out
for review
9) Rhodes, N.R., Shi, Y., Abdolvahabi, A., Cook, N.P., Kohn, T., Mowery, R.A., Marti, A.A.,
Shaw, B.F. Acetylation of lysine in Cu, Zn superoxide dismutase by an aryl ester
electrostatically inhibits its self-assembly into amyloid Finalizing before being sent to
JACS
Nicholas R. Rhodes Ph.D. Page 3
AWARDS AND HONORS
Outstanding Second Year Graduate Student Award, UA 2009