Medical Clinical Research

Jes Paul

**** *. **** ***: ***

El Paso Texas ***12

Phone: 915-***-****

E mail:**********@*****.***

Career Objective

Seek an opportunity for personal growth and professional advancement in the field of

Medical science. Advance clinical research along with medical practice to achieve results and

scale great heights in my medical profession.

Career Capabilities

I am a researcher with extensive exposure in the field of Molecular Neuro Biology and

Clinical Science with keen understanding of the dynamics of the sector with good experience

in method development and validation. I have written and verbal communication skills with

strong analytical, problem solving and organizational abilities. Possesses a flexible and detail

oriented attitude.

Education

• Ph. D in Molecular Neurobiology (2007-2011)

Cochin University of Science & Technology in the Centre for Neuroscience, Department

of Biotechnology, CUSAT

• Master of Medical biochemistry (2003- 2006)

Mahatma Gandhi University, India

• Bachelor of Science in Zoology (1999-2002)

Mahatma Gandhi University, India

Experience

• Three and half year experience as Senior Research Fellow (Molecular Neurobiology )in

Cochin University, INDIA.

• One-year experience as a Post-Doctoral Researcher (Neurological Surgery-Spinal Cord

Regeneration-Stem Cell) in Ohio State University, USA.

• Working as a Post-Doctoral Associate Scientist (Neuro Science-Spinal Muscular

Atrophy) in Texas Tech University, USA from 06/01/12

Publications

Published 13 papers in various international journals (PubMed).

Presented 15 Abstract in various international conferences.

Curricular Achievements

• P.G. Diploma in Research and Development (IIT, INDIA)

• Diploma in Clinical Research (NIH, USA)

• Diploma in Clinical Research (PDCR, INDIA)

• P.G. Diploma in Nano Biotechnology (P.G. DNB, INDIA)

CURRICULUM VITAE

Name Jes Paul

Address 7133 N. Mesa

APT:169

El Paso, TX-79912

Languages known English, Malayalam, Tamil, and Hindi.

EXTRACURRICULAR ACTIVITIES

Participated in sports activates like Cricket, shot-put, discus throw, hammer throw and running at

State and National levels.

RESEARCH EXPERIENCE

• Worked as a Post-Doctoral Researcher (neurological surgery department- spinal cord

regeneration study-stem cells) in Ohio State University (May 2011-May 2012)

• Working as a Post-Doctoral Associate Scientist (neuro science department- spinal

muscular atrophy study) in Texas Tech University (June 2012- till date)

ACADEMIC RECORDS

• Ph. D in Molecular Neurobiology (2007-2011)

Cochin University of Science & Technology in the Centre for Neuroscience, Department

of Biotechnology, CUSAT

• Master of Medical biochemistry (2003- 2006)

Mahatma Gandhi University, India

• Bachelor of Science in Zoology (1999-2002)

Mahatma Gandhi University, India

AWARDS:

• Best Poster Awarded in 7th Annual Research colloquium in Texas tech university (2013).

• 4th Rank in M.Sc. (Medical Biochemistry), M.G. University, INDIA, 2006

• 2nd rank in Department admission test (DAT). Department of Biotechnology, Cochin

University of Science and Technology, INDIA, 2008.

• 1ST rank in Indian Council of Medical Research Examination (ICMR, 2009).

• 2nd rank in Ph. D Qualifying Exam, Department of Biotechnology,

Cochin University of Science and Technology, INDIA, 2010

• ISN / APSN Travel Award for Participating in ISN / APSN School and 10th

Biennial Meeting of the Asia-Pacific Society for Neurochemistry (APSN)

Bangkok, Thailand.

(October 2010).

CURRICULAR ACHIEVEMENTS

• P.G. Diploma in Research and Development (IIT, INDIA)

• Diploma in Clinical Research (NIH, USA)

• Diploma in Clinical Research (PDCR, INDIA)

• P.G. Diploma in Nano Biotechnology (P.G. DNB, INDIA)

INTERNSHIP TRAINING PROFILE:

1. Worked as a Junior Research Fellow in the Centre for Neuroscience, Department of

Biotechnology, Cochin University of Science & Technology in ICMR Project entitled

Dopamine Receptor Subtypes, IP3, cAMP and cGMP Functional Regulation in

Parkinsonism Induced by Unilateral Infusion of Rotenone in Rats: Recovery with

Bone Marrow Cells, Serotonin and GABA Supplementation (2007-2011).

2. Worked as Research Fellow in the Centre for Neuroscience, Department of

Biotechnology, Cochin University of Science & Technology 2007-2011.

3. Five months training in Biochemistry and Microbiology Lab, Dianova Diagnostic Centre,

Kerala, India

RESEARCH INTERESTS

Neuroscience, Stem Cells

Cellular and Molecular Biology

Molecular and neurobiological mechanisms of Neuro Degeneration

RESEARCH PROJECTS UNDERTAKEN:

PG PROJECT: “Biochemical study of costus pictus, streptozotocin induced Diabetic Rats.

UG PROJECT: “Risk factors of breast cancer.”

MEMBERSHIP IN SCIENTIFIC SOCIETY

1. Life Member, Society for Biotechnologists, (India)

2. Life member of Society for Neurochemistry, (SFN)

3. Life member of International Brain Research Organization, (IBRO)

TECHNICAL SKILLS:

Confocal Microscope

Stereology

Metamorph

Transfection

Cloning

EM(Electron Microscope)

High Performance Liquid Chromatography (HPLC)

Ultra Centrifuge

PCR and Real-Time PCR

Gel Documentation System

Liquid Scintillation Counter

Gamma Counter

EEG Recorder

Stereotaxic Equipment

CO2 Incubator

Inverted Phase Contrast Microscope

Spectrophotometer

• Familiar with techniques like

Animal tissue culture - Isolation and Culture of Hepatocytes and Pancreatic

Islets

Isolation of RNA and DNA

RT-PCR, Real-Time PCR

Gel Electrophoresis - Agarose gel electrophoresis, SDS PAGE

Radio Receptor Assays

Second messenger assays - cAMP, cGMP & IP3 assay.

• Induction of Hypoxia, Epilepsy, Diabetes and Hypoglycemia in rat

model.

• Contusion of spinal cord injury and stem cell transplantation.

• Experience in surgical procedures like

Brain Dissection

Partial Pancreatectomy

Partial Hepatectomy

Adrenalectomy

Laminectomy

Spinal cord Dissection

Nano particle encapsulation in liver

• Perform enzyme assays like Acetylcholine Esterase, Glutamate dehydrogenase and

Malate dehydrogenase.

IMAGING TECHNIQUES

1. Double labeling techniques using Fluorescent and Electron Microscopy.

2. Intracellular calcium monitoring- Fura-2 labeling, and measurement of calcium

dynamics in cells and organelles using Confocal Microscope.

3. DAB Staining and Stereology

ANIMAL TISSUE CULTURE -

Primary cultures – attached & suspension cultures of Pancreatic β -cells and

1.

Hepatocytes.

Primary & Secondary Neurosphere culture

2.

Stem Cell Culture

3.

ANIMAL HANDLING:

1. Surgical skills including partial hepatectomy, pancreatectomy, adrenalectomy and

stereotaxy.

Induction of diabetes in rats using streptozotocin.

4.

Induction of epilepsy in rats by pilocarpine administration.

5.

Induction of hypoglycemia and hypoxia in rats.

6.

Tag and Tailing

7.

Genotyping

8.

COMPUTER KNOWLEDGE:

1. Softwares such as GraphPad Prism, GraphPad Instat Excel, Empower HPLC

Software, Relative Quantification Software for analyzing Real Time PCR and Sigma

Plot.

2. Computer skills with JAVA, MS-Office, Internet.

TEACHING:

Supervising, planning, execution, and writing up of thesis, of graduate student projects.

Contact this candidate