Medical Management
Resume:
RAJNI KANT SHUKLA, M.Sc (Biotechnology) PHD
Department of Pulmonary Medicine, King George’s Medical University (KGMU), India
Phone: +91-941******* Email: ab0l55@r.postjobfree.com
Date of Birth: 01-07-1983 ab0l55@r.postjobfree.com
Objective:
Seeking a research position in molecular biology and pharmaceutical sciences especially in the
role of genetics in complex disorder, Pharmacogenomics, molecular epidemiology and related
areas with an opportunity to work with persons who can help me to maximize my potential and
knowledge as a valuable future researcher.
Current Position: Research Associate (RA) under the supervision of Dr. Sandeep
Bhattacharya, Associate Professor, Dept of Physiology, King George’s Medical University,
Lucknow, India.
Education:
• Ph.D in Medicine January 2013, King George’s Medical University, Lucknow, India
Topic: “Association of glutathione-s-transferase (GST) and Cytokine gene polymorphism
in chronic obstructive pulmonary disease”.
Supervisor: Dr. Surya Kant, Professor & Head, Department of Pulmonary Medicine, King
George’s Medical University (KGMU), India.
• Master in Science (M.Sc): In Biotechnology July 2004-June2006, C. S. J. M.
University, Kanpur, India (Distinction Honors)
• Bachelor of Sciences (B. Sc): Kanpur B.N.D College, C. S. J. M. University, Kanpur,
India, (Subject-Zoology, Botony, Chemistry) 2003.
HONORS/AWARDS:
• I have awarded various international and national travel awards like European
Respiratory Sociciety (ERS), ICMR, CICS, DST, DBT.
Publications:
1. Shukla RK, Tilak A, Chandan K, Kant S, Mittal B, Kumar A,. Bhattacharya S, Association
of CYP1A1, GSTM1 and GSTT1 gene polymorphisms in lung cancer susceptibility in a
northern Indian population. Asian Pacific J Cancer Prev, 14 (5), 3345-
3349(DOI:http://dx.doi.org/10.7314)
2. Shukla RK, Kant S, Bhattacharya S, Mittal B. Association of Genetic polymorphism of
GSTT1, GSTM1 and GSTM3 in COPD Patients in a north Indian population. COPD:
Journal of Chronic Obstructive Pulmonary Disease May 2011, Vol. 8, No. 3: 167–172.
[PMID:21513434] (doi:10.3109/15412555.2011.560128) (Cit:7)
3. Shukla RK, Kant S, Bhattacharya S, Mittal B. Association of Cytokine Gene
Polymorphisms in COPD Patients. Oman Medical Journal (2012) Vol. 27, No. 4: 286-29.
PMID:23071879] (DOI:10.5001/omj.2012.71) (Cit:2)
4. Shukla RK, Kant S, Bhattacharya S, Mittal B. Association of clinical symptoms with
smoking quantity in northern Indian COPD patients at tertiary care hospital.
International Journal of Biological & Pharmaceutical Research. 2012; 3(4): 545-549.
5. Kumar C, Shukla RK, Kant S Awasthi S and Bhattacharya S. Genetic Association of
glutathione-s-transferase gene Polymorphisms in Bronchial Asthma Patients: a study in
northern India. International Journal of Biological & Pharmaceutical Research. 2012; 3(4):
502-506.
6. Shukla RK, Kant S, Mittal B, Bhattacharya S. Polymorphism of Cytochrome p450,
Glutathione-S-Transferase and N-acetyltransferases: Influence on Lung Susceptibility.
Niger J Med 2010: 257 –263.[PMID:20845626] (Cit:2)
7. Shukla RK, Kant S, Bhattacharya S. Lung cancer and genetics. Journal of Physiology
2009;Vol. IX: 62-63.
8. Surya Kant, Rajni Kant Shukla, Sandeep Bhattacharya, Balraj Mittal. Role of cytokine in
development of Chronic Obstructive Pulmonary Disease (COPD). Journal of Physiology
2008;Vol. VII:15-18.
9. Shukla RK, Kant S, Mittal B, Bhattacharya S Comparative study of GST polymorphism
in relation to age in COPD and Lung cancer. Post Graduate Medicine 2013 (Under
Communication).
BOOK CHAPTERS:
1. Rajni Kant Shukla, Priyanka Jain, Sandeep Bhattacharya, (2009) “Biological
Characteristics of Histamine Receptors in Airways Disease Management”. In:
Biomedical Aspects of Histamine: Current Perspectives. (ISBN: 978-90-481-9348-6), Eds.
M. Shahid, N Khardori, RA Khan, T Tripathi. Springer-Verlag, Netherlands; 2010, pp 227-
243.
Young Scientist Presentations:
1. Rajni Kant Shukla, Kant S, Mittal B, Bhattacharya S “GSTT1 Null Polymorphisms,
Tobacco smoking and Lung Cancer: A Study in northern India”. NALCCON Indore,
April-2011.
2. Shukla RK, Kant S, Mittal B, Bhattacharya S. “Genetic Polymorphism of GlutathioneS-
Transferase (GST)and Susceptibility to Chronic Obstructive Pulmonary Disease
(COPD)”. ICCAICON Chandigarh, Nov-2009.
Abstract Published: (International)
1. RK Shukla, S Kant, S Bhattacharya, B Mittal. Association Of CYP1A1, NAT2, GSTT1
Gene Polymorphism With Lung Cancer Patients In Northern India
Population.JOURNAL OF THORACIC ONCOLOGY 2012 7 (7), S105-S105. [IP3.66]
2. Shukla RK, Kant S, Bhattacharya S, Mittal B. Association of GSTT1 & M1 gene
polymorphism with ageing in Northern Indian COPD and lung cancer patients.
European Respiratory Journal 2012; 6: 879S-882S.
3. Sandeep Bhattacharya, Rajni kant Shukla,Surya Kant, Balraj Mittal. NAT2 gene
polymorphism in lung cancer: A study from north India. European Respiratory Journal
2012; 30: 732S-736S.
4. Shukla RK, Kant S, Bhattacharya S, Mittal B. Association of IL-1ß (-511 C>T) and
IL1RN 86-bp VNTR polymorphism susceptibility with chronic obstructive pulmonary
disease between male and female Patients in Northern Indian Population. . European
Respiratory Journal2011; 38:S55:57s [impact factor- 5.90]
5. Bhattacharya S, Tilak A, Shukla RK, Kumar A, Kant S, Mittal B. “GSTT11 and CYP1A1
Polymorphisms, Tobacco smoking and Lung Cancer: A Study in northern India”.
European Respiratory Journal2011; 38:S55:690s [impact factor- 5.90].
6. Rajni Kant Shukla Sandeep Bhattacharya,, Surya Kant,Rohit Upadhyay, Balraj Mittal
.Association of GST gene polymorphism with the lung function of COPD patient in
northern India population. European Respiratory Journal2010; 36:S55:289s [impact factor-
5.90]
7. Sandeep Bhattacharya, Rajni Kant Shukla, SuryaKant, Rohit Upadhyay, Balraj Mittal.
Association of GSTT1,GSTM1 and CYP1A1MSP1 gene polymorphism with lung
cancer patients in north Indian population.. European Respiratory Journal2010;
36:S55:933s. [impact factor- 5.90]
Work/Research Experince:
• January 3rd 2013- Till Date: - Research Associate (RA) Dept of Physiology, King George’s
Medical University, Lucknow, India.
• November 2011- January 3rd 2013: Senior Research Fellow (SRF) Dept of Physiology,
King George’s Medical University, Lucknow, India.
• June 2007- June 2010: Junior Research Fellow (JRF), Dept of Physiology, King George’s
Medical University, Lucknow, India.
• March 2008-December 2008 (Part Time): Worked as Clinical Co-ordinator, Sponsored
by Quintiles India 2007
• June 2005- August 2005: Trainee, Central Drug Research Institute (CDRI), Lucknow, India.
Topic: “Study of Drug diagnosis and enzyme involved in drug resistant malaria parasite and
standardization of Cytochrome p450 enzyme in the host liver” Supervisor: Dr.Renu
Tripathi, Scientist, Division Parasitology, Central Drug Research Institute (CDRI),
Lucknow, India.
Technical Skills:
• Having the proficiency in following Molecular Biology techniques & I can perform all
these techniques independently
•
Molecular Biology DNA and Plasmid Isolation,
• Elution of DNA from agrose gel,
• PCR, Multiplex PCR,
• Taq man Probe Genotyping
•
Enzyme Assay Cytochrome P450 Enzyme Assay
•
Immunological Immunohistochemistry (IHC)
Techniques
Protein estimation
•
Centrifugation Ultra Centrifuge,
• Double Beam Spectrophotometer,
• Tissue Homognizer
•
Mice Handling Swiss Mice,
• Maintenance of Laboratory Infection,
• Passage,
• Inoculation of Parasite,
• Preparation of blood films,
• Dissection of Mice,
• Drug Dosing,
•
Staining Giemsa Staining,
• Acridine Orange Staining
Microscopy
• Bacterial and Fungal
Culture
Clinical Data
Management
•
Computational SPSS,
•
Tools and strategies Arlequin software, ver. 2.00,
•
in Biomedical BLAST FAST CLUSTAL W/X,
•
Sciences Primer Deigning (Primer 3),
• SNP analyzer,
• Quanto
• Operating Systems: Windows 7/Vista/XP/NT/2000/98, Microsoft
Office Excel,Word, PowerPoint, Access
•
Coursework Molecular Biology
• Research Ethics
• Research Methodology,
• Genetics,
• Microbiology,
• Biochemistry
COURSE/WORKSHOP ATTENDED:
1. Postgraduate course. Genetics and Genomics. Amsterdam Netherland. 24 -28th Sept,
2011, (Sponsored By ERS 2011)
2. Genotyping Technique In Clinical Diagnostics” Mumbai, India held on 28th April to 14th
May, 2008.(Sponsored by ICMR & DBT).
3. Workshop on Computer and Informatics in Medicine. Biomedical Information Databases,
Computerized Patient Data and Image Management. Lucknow,India (30th August - 31st
August, 2008)
4. Workshop On “Prevention Of Lead Poisoning”, 29th March 2008, .(Sponsored by ICMR),
Lucknow, India
5. Training Cum Workshop on “Cytokine Assay” India held on 2008. .(Sponsored by ICAR)
MEMBER OF INTERNATIONAL/NATIONAL BODIES or SOCIETIES:
1. European Respiratory Society, (Annual Member)- 22673
2. American Society of Human Genetics (ASHG)- 307832
3. American Association of Cancer Research, (AACR),Associate Member-271185
4. American Thoracic Society (ATS) - 00193033
5. India Science Congress, (Student Member)-A2909
6. Biotech Society of India, (Annual Member)
7. The Association of Physiologist and Pharmacologist of India, (Annual Member).
8. Member of Editorial board member in SCHOLARS ACADEMIC JOURNAL OF
PHARMACY (SAJP); ISSN-2320-4206
(RAJNI KANT SHUKLA)
Name Position Department/Institute Contact
Department of Pulmonary ab0l55@r.postjobfree.com
Dr. Surya Kant, MD Professor
Medicine, ab0l55@r.postjobfree.com
&
King George’s Medical +91-941*******
Head
University
KGMU, Lucknow, 226003
India.
Department of Genetics,
Dr. Balraj Mittal, PhD Professor ab0l55@r.postjobfree.com
Sanjay Gandhi Post Graduate ab0l55@r.postjobfree.com
Institute of Medical Sciences ab0l55@r.postjobfree.com
SGPGIMS,Rai Barely Road, Phone: 91-522-******* Ext.
Lucknow 226014 India. 2322 (O); 2323 (R) Fax: 91-
Department of Physiology,
Dr. Sandeep Associate ab0l55@r.postjobfree.com
King George’s Medical +91-941*******
Bhattacharya, MD Professor
University
KGMU, Lucknow, 226003
India
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