Senior CADD Scientist

Genesis Molecular AI is assembling a world-class computational chemistry team to revolutionize drug discovery through cutting-edge machine learning and biophysical simulation.

We are seeking a Senior CADD Scientist to join our team, working directly with scientists in our state-of-the-art wet lab and with our distributed computational chemistry and CADD science teams across the US.

What You Will Do (Key Responsibilities) * Utilize a combination of industry-standard and proprietary AI-powered CADD tools to guide small molecule drug discovery programs across a diverse target portfolio, including novel targets with limited chemical precedents.

* Use approaches like virtual screening, molecular simulation, and potency and ADMET prediction to support key decision-making in drug discovery efforts.

* Collaborate closely with medicinal chemists in molecular design and the development of project-specific computational approaches.

* Act as a cross-team connector, effectively communicating between our computational chemistry and medicinal chemistry teams to ensure seamless information flow and collaborative decision making.

* Adapt to a fast-paced environment where innovation and quick iteration are encouraged.

What you'll bring * PhD in Computational Chemistry, Structural Biology, or a related field.

This particular role may also be suitable for PhD-level scientists with degrees in organic or medicinal chemistry with extensive experience in the lab, who have transitioned into industry roles in CADD.

* Deep understanding of structure-based drug design and protein-ligand interactions.

* Proficiency with industry-standard CADD tools such as MOE, PyMOL, and Schrodinger Suite.

* Minimum of 2+ years of industry experience as a CADD scientist in pharma or biotech, with hands-on experience in active drug discovery programs.

* Onsite in our San Diego lab is preferred for this role, to be able to collaborate with our scientists.

We are open to remote team members too.

What we offer * Competitive Pay * Health Care Plans (including Medical, Dental, and Vision, fully covered for the employees) * Stock Option Eligibility * 401(k) Plan * Open PTO Policy * Paid Company Holidays * Subsidized lunch and snacks at our offices Genesis Molecular AI is pioneering foundation models for molecular AI to unlock a new era of drug design and development.

The company's generative and predictive AI platform, GEMS (Genesis Exploration of Molecular Space), integrates AI and physics into industry-leading models to generate and optimize drug molecules, including the breakthrough generative diffusion model Pearl for structure prediction.

Genesis has raised over $300 million from leading AI, tech and life science-focused investors, signed multiple AI-focused research collaborations with major pharma partners, and is deploying GEMS to advance an internal therapeutics pipeline for a variety of high-impact targets.

Genesis is headquartered in Burlingame, CA, with a fully integrated laboratory in San Diego.

We are proud to be an inclusive workplace and an Equal Opportunity Employer.