Executive - API R&D

Role:

To execute activities related to R&D Peptide Process Development & Scale-ups, along with a group comprising of Research Officers/ Research Assistants in co-ordination with Team/Group Leader

Details of Previous Work Experience (Mandatory Requirement)

Literature search and ROS (Route of Synthesis) finalization

Basic knowledge of Orthogonal protected amino acid and Peptide

Solid phase peptide Synthesis/Oligonucleodtide Synthesis

Handling of hazardous chemical like Trifluoroacetic acid

Knowledge of handling of analytical HPLC/Oligo Synthesis

Purification using Preparative HPLC

Preparative column packing and usage.

Computer literacy etc.

Knowledge of Phosphoramidalin /handling/storage

Job Description:

● Literature search with respect to assigned project and finalizing the non-infringing synthetic route

● Experimentation (Process development, DoE study, optimization and validation).

● Purification of Peptide and knowledge of lyophilisation of pure solution.

● Handling of analytical HPLC and preparation of buffer.

● Characterisation of Peptide using HRMS,2D NMR, IR, Peptide mapping and sequencing.

● Preparation of Technology transfer documents.

● Scaling-up of process developed at R&D.

● Assisting to RA in filing DMF.

● General Laboratory Management etc.