Structural Immunology Faculty Search - Open Rank/Tenure-Track

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Job Title:Structural Immunology Faculty Search - Open Rank/Tenure-Track

Department:Medicine School Biomedical Sciences Biological Chemistry and Pharmacology

The Ohio State University College of Medicine and the Wexner Medical Center seek a tenure-track faculty to join the Department of Biological Chemistry and Pharmacology and the Pelotonia Institute for Immuno-Oncology. Candidates at the rank of Associate Professor are preferred, but other ranks will be considered. Academic rank and track commensurate with academic record and experience.

Position Overview

The Department of Biological Chemistry and Pharmacology and the Pelotonia Institute for Immuno-Oncology (PIIO) at The Ohio State University invite applications for a tenure-track faculty to lead an independent research program focused structural biology and immuno-oncology with an emphasis on molecular mechanisms of immune regulation in cancer. The faculty would leverage OSU's cryo-EM, NMR, X-ray crystallography, and computational biology resources to study protein-protein and protein-ligand interactions in immune pathways. Candidates at the rank of Associate Professor are preferred, but other ranks will be considered. Academic rank of the successful candidate will be determined based on qualifications and experience, including demonstrated excellence in research, teaching, service, and leadership.

Duties and Responsibilities

Tenure faculty (regardless of rank) - persons with the titles of professor, associate professor, assistant professor, and instructor who serve on appointments totaling 50% or more service to the university and who are eligible for tenure or who have obtained tenure. Duties and responsibilities are assigned in accordance with the workload guidelines laid out in the pattern of administration of each faculty member's tenure initiation unit (TIU) and, as appropriate, regional campus; obligations will include research, service and/or teaching or clinical practice. These faculty will have earned doctorate or other terminal degree in the relevant field of study or possession of equivalent experience.

Requirements

Applicants must have a Ph.D. and/or M.D. in biochemistry, immunology, molecular biology or an associated field with expertise in structural biology, immunology, and oncology; a strong record of high-impact publications and sustained extramural funding; and demonstrated success in interdisciplinary collaboration and mentoring.

Department/Division Overview

The Department of Biological Chemistry and Pharmacology is home to research and education focused on understanding the molecular mechanisms of fundamentally important life processes. The department is host to a broad range of research, education and service programs spanning across the basic and translational sciences . The department's mission is to advance research and education in fundamental biochemical, pharmacological, and cellular processes that drive human health and disease. BCP offers access to world-class research facilities and fosters a highly collaborative environment for exploring molecular mechanisms and therapeutic interventions. Faculty members in BCP are leaders in applying structural, biochemical, and pharmacological approaches to solving complex biomedical challenges.

The PIIO is a comprehensive bench-to-bedside research initiative focused on harnessing the body's immune system to fight cancer at all levels . Led by founding director Zihai Li, MD, PhD, the PIIO builds upon a rich portfolio of active investigator-initiated IO clinical trials being conducted at the OSUCCC - James. PIIO faculty conduct research in Systems and Translational IO. The PIIO is supported by our Immune Monitoring and Discovery Platform (IMDP), which provides comprehensive cell-based and molecule-based immunoassay services to support basic, translational, and clinical IO studies. The PIIO's Immuno-Oncology Informatics Group (IOIG) provides data analytics for flow and mass cytometry, bulk and single-cell RNA-Seq, spatial transcriptomics and imaging, neoantigen discovery, and more.

Ohio State is also home to the Native MS Guided Structural Biology Center, a state-of-the-art facility dedicated to advancing structural biology research. The center provides researchers with access to specialized mass spectrometry technologies, enabling detailed analyses of protein complexes, their interactions, and dynamics in native-like states. This resource complements OSU's existing structural biology infrastructure, offering unique capabilities for studying molecular mechanisms and therapeutic targets in cancer immunology and beyond.

How to Apply

To be considered, please submit your application through Workday. Application materials must include a cover letter, curriculum vitae, a statement of research (up to 3 pages), a teaching statement, and a list of 3 references. In the teaching statement, please outline your approach to teaching and learning and your goals and vision as an educator. Applications received by August 15, 2025 will receive priority consideration. All inquiries should be directed in confidence to Jessica Berner .

Additional Information:

Faculty Defined

Clinical faculty (regardless of rank) - Persons with titles of assistant professor-clinical, associate professor-clinical and professor-clinical. These faculty will have earned a doctor of medicine (MD), doctorate (PhD) or other terminal degree in the relevant field. Clinical faculty members are not eligible for tenure and are appointed for terms of three to five years. They may be reappointed to successive terms. Their principal career focus is the delivery of exemplary clinical care, and may include teaching, and/or research.

Tenure-Track faculty (regardless of rank) - Persons with the titles of assistant professor, associate professor, or professor who are eligible for tenure or who have obtained tenure. These faculty will have earned a doctorate (PhD), Doctor of Medicine (MD) or other terminal degree in the relevant field of study. Their primary career focus centers on research, service, and teaching. Tenure-track faculty with MD or MD/PhD degrees may also be involved in clinical care.

Research Faculty (regardless of rank) - Persons with the titles of research assistant professor, research associate professor, or research professor. These faculty will have earned a doctorate (PhD) or other terminal degree in the relevant field of study. Research faculty members are not eligible for tenure and are appointed for terms of one to five years. Their principal career focus is research.

The Ohio State University College of Medicine

The Ohio State University College of Medicine, with more than 5,000 learners, is the only academic medical center in central Ohio. Ranked as the 28th Best Medical School - Research, 40th Best Medical School - Primary Care, it is known nationwide for curricular innovation, pioneering research, and outstanding patient care at The Ohio State University Wexner Medical Center. With more than 2,600 faculty members, the college comprises 20 clinical departments, eight basic science departments and a School of Health and Rehabilitation Sciences.

The Wexner Medical Center

The Ohio State University Wexner Medical Center consists of The Ohio State University Health System, the College of Medicine, the Health Sciences Library and the Faculty Group Practice. The Ohio State Wexner Medical Center is committed to providing world-class care. At the Ohio State Wexner Medical Center, we're proud to be celebrating our 31st consecutive year ranked in the U.S. News & World Report Best Hospitals list. This year, the Ohio State Wexner Medical Center has 10 nationally ranked specialties out of 15 and two selected as high performing. U.S. News & World Report consistently ranks the Ohio State Wexner Medical Center as the top hospital in Columbus. The Wexner Medical Center is rated as high performing in 14 out of 20 common procedures and conditions, including abdominal aortic aneurysm repair, aortic valve surgery . click apply for full job details

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