Vice President, Clinical Operations

Join Us in Tackling Autoimmune Disease at Its Root

At Vor, we believe science can do more than manage symptoms. It can change the course of disease. By advancing telitacicept, a first- and potentially best-in-class dual BAFF/APRIL inhibitor, we are silencing upstream survival signals and stopping downstream autoimmune cascades. Together, we are addressing disease at its root cause and rewriting what is possible for patients worldwide.

When you join Vor, you're not just working on a medicine. You're part of a mission to redefine the future of autoimmune care.

Why Work at Vor?

Impact: Contribute directly to a medicine with best-in-disease Phase 3 results in myasthenia gravis and expansion into multiple autoimmune diseases.

Growth: Be part of a rapidly scaling company with opportunities to grow your career in science, clinical development, commercial strategy, and beyond.

Innovation: Work on a platform with potential beyond one indication - a therapy that has already shown consistent results across lupus, IgA nephropathy, and Sjögren's syndrome.

Belonging: Join a culture where every voice is heard, and where our shared mission unites us across functions and geographies.

Who we are looking for:

Vor Bio is seeking a Vice President of Clinical Operations.

Primary Responsibilities

Define strategic direction for an integrated project team for all the indication / clinical development programs

Lead operational resource planning, implementation, and execution to support multiple global clinical trials

Develop, maintain, and report on program budgets, including forecasting in support of financial goals

Define and help manage the development of clinical study protocols, documents, procedures, study reports, charters, presentations, and publications

Manage clinical study leads / managers and clinical research associates

Create team study training, tools and metrics and monitor accordingly

Identify outsourcing model best suited for clinical development success

Identify vendors, perform capabilities assessments, and conduct formal request proposal process (RFP) including summary evaluation of key factors and bid defense

Act as point of contact for escalation management of external vendors and / or CROs

Prepare and present key study updates to senior management, and other key stakeholders

Involved in building relationships with trial site and KOLs to maximize scientific expertise, patient recruitment and data collection

Ensure advocacy and voice of the patient is represented in planning, design and conduct of clinical trials

Education and Experience

Bachelor's or master's degree in scientific, biological, life sciences, or related field

At least 15 years of clinical trial management experience with at least 5 years in a leadership role with proven record of accomplishment of people and project management

In-depth knowledge of clinical operations and pharmaceutical drug development process in the autoimmune therapeutic area, or in rare diseases, preferred.

Technical expertise in and / or understanding of cross-function clinical trials processes from study start-up through study closure (e., data management, safety, biostatistics, medical writing)

Experience managing global studies

Working, in-depth knowledge of industry standards including ICH guidelines, GCPs and the CFR; familiarity with EMA / CHMP regulations and guidelines and other international regulatory requirements is a plus

Experience with NDAs, MAA, or other agency new drug application submissions

Track record of excellence in effective management of multiple projects / priorities and budgets, ranging from early to late stage development programs

Understanding of comprehensive global pharmaceutical regulatory requirements and strategic implications for clinical development operations

Demonstrated, effective project management skills

Ability to work independently, take a leadership role and drive quality progress

Ability to assess complex issues and identify creative, practical solutions

Ability to foster effective relationships with vendors, investigators, consultants and colleagues

Demonstrated ability to work independently as well as in a team environment

Excellent written, oral and presentation communication skills

Proficiency in Microsoft Project and / or other project management software and tools and Microsoft Office (Excel, Word, Outlook, PowerPoint)

At Vor, we support our team with robust benefits, including comprehensive health coverage, flexible paid time off, generous parental leave, and a competitive 401(k). From education assistance to wellness resources and financial security, we invest in your well-being so you can thrive at work and beyond.

As an equal opportunity employer, we at Vor Bio know that diversity inspires innovation, inclusiveness, and creativity. We invite you to come as you are. All applicants will be considered for employment agnostic to race, age, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

Please visit our website at for more information.