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Group Leader, Immunology

Company:
NewLimit
Location:
South San Francisco, CA, 94083
Posted:
September 18, 2025
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Description:

Company info

NewLimit is a biotechnology company working to radically extend human healthspan. We're developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells. We leverage functional genomics, pooled perturbation screening, and machine learning models to unravel the biology of epigenetic aging and disease using experiments of unprecedented scale.

Description

NewLimit is seeking an immunologist or synthetic biologist with leadership experience in therapeutics to lead our Immunology team. Our Immunology program is developing reprogramming medicines to restore youthful function in aged T cells for the treatment of inflammatory & infectious diseases.

As the leader of Immunology team, you will:

Lead a team of Scientists and Research Associates to develop reprogramming therapies

Develop functional assays and pre-clinical models for inflammatory and infectious disease indications

Evaluate reprogramming payloads using functional assays & pre-clinical models to validate payloads, select leads, and progress pre-clinical candidates

Collaborate with our Single Cell Technology, Epigenetic Editing, and Predictive Modeling teams to design, build, and test reprogramming interventions

Contribute to NewLimit's product development decisions, company-wide goals, and technology platform. You will be a key part of building the company in addition to your team.

Contribute to day-to-day execution alongside your team. Everyone Executes at NewLimit.Requirements

Ph.D. in cell biology, immunology, or a related field or comparable industry experience

Experience leading a team and managing direct reports

Experience with therapeutics development, ideally leading a portion of a discovery or development process in an immunology, infectious disease, or inflammatory disease setting

Deep knowledge of immunology & lymphocyte biologyNice to have

Direct experience with T cell biology, including relevant functional assays, pre-clinical models, and experimental methods

Experience with in vivo nucleic acid delivery technologies

Experience with pooled screening and related functional genomics methods

Strong molecular biology foundations and experience designing transgenic constructs

Experience with iterative product development cycles (e.g. design-build-test-learn)

Knowledge of aging biology, computational biology, and machine learningBenefits

NewLimit offers generous benefits to ensure our team can focus on our mission:

Health, dental, and vision insurance

401(k) with company match

Paid parental leave

Industry-leading paid time off (PTO) - 20 days/year for all employees + holidays

Meals and snacks on-site

Compensation for the role will depend on a number of factors, including a candidate's qualifications, skills, competencies, and experience. Learn more at: *This compensation and benefits information is based on Company's good faith estimate as of the date of publication and may be modified in the future.

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