Bench Scientist
Description:
Job Description
Description:
Manufacturing Sciences and Technology (MSAT) Upstream Group is looking for a highly motivated and versatile candidate to join our multidisciplinary team of scientists and engineers in Andover, MA.
MSAT supports portfolio of late-stage development of commercial biopharmaceuticals and vaccines, and is responsible for process troubleshooting, process improvements and second- generation process development.
We are looking for someone who is eager to contribute independent thinking and technical excellence to the upstream fermentation team.
The Scientist will be a part of a diverse and motivated team of scientists, engineers, and technical professionals that are focused on fermentation processes to produce biotherapeutics.
The role is well-integrated into the rest of the MSAT Microbial Team.
This role will collaborate with other MSAT scientists to setup bioreactors and execute well-designed experiments, including but not limited to basic analytics, data acquisition and documentation of work.
The candidate would also be responsible for user-level maintenance of the relevant equipment and associated documentation.
Plan and execute upstream process experiments at benchtop scales
Participates and significantly contributes to discussions in lab and project team meetings on design of experiments (bioreactor and shake flask) and interpretation of experimental data.
Acts as a technical resource within the upstream group. Provides formal/informal mentoring to junior colleagues within work group/project team.
Works under limited supervision with periodic review of achievement of results and experimental approaches employed.
Manages own time to meet agreed targets. Develops plans for short-term work activities on own projects.
Ensures effective, high-quality, timely and appropriate documentation in electronic laboratory notebooks and internal technical reports; presents data/ strategy to scientists and management in appropriate internal and external venues (technical meetings, project team meetings, conferences) as appropriate.
Contributes to safe, efficient, effective and harmonious lab environment, ensures appropriate cleanliness and status/ operability of shared or assigned lab space or equipment; strong lab citizen and collaborative team player; approaches the job with energy and commitment; frequently demonstrates initiative.
Participate in multi-disciplinary teams to resolve complex issues
Assist in manufacturing investigations and process troubleshooting
Assist on process improvement projects
Qualifications
Ph. D. with 0-4 years of experience in biotechnology ;OR
Master's degree in a relevant discipline with at 3-5 years of applicable bioprocess experience ;OR
Bachelor's degree with at least 7 years of experience
Proficient in aseptic technique (required)
Proficient in benchtop bioreactor operation and associated analytical tools (required)
Experience with bench scale cell culture and/or bacterial fermentation (required)
An in-depth knowledge of bioreactor operations fed-batch, perfusion, and continuous modes of cell culture
Strong trouble-shooting skills and extreme attention to detail required
Ability to troubleshoot technical issues, plan and carry out experiments independently, and work with complex instrumentation and software.
Excellent oral and written communication skills.
Strong analytical and computer skills.
Involves typical bioprocessing lab activities
Ability to routinely lift 50 lbs.
Standing for prolonged periods of time, walking, bending, and using tools.
Ability to perform mathematical calculations and ability to perform complex data analysis.
Preferred:
Prior experience developing and maintaining scale down models of commercial biopharmaceutical processes
Prior experience in developing commercially relevant cell culture processes to produce pharmacologically active proteins
Experience with control and data acquisition systems
Demonstrated experience developing or introducing new technology into commercial processes
Knowledge of all aspects of cell culture/fermentation, including batch, fed-batch, perfusion and harvest/clarification operations
Familiarity with DoE and other statistical tools
Experience with processing and interpreting large data sets
Familiarity with regulatory filings, cGMP requirements and operational constraints
Benefits:
Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through BlueCross BlueShield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics.
Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.
Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first enrollment date that is at least 30 days after employment begins. Enrollment dates are each January 1st, April 1st, July 1st, and October 1st.
Technical Certification Bonus: Synectics is pleased to award its employees a bonus of up to $500 for an approved professional certification. In determining the bonus amount, Synectics will consider the cost of the test(s) for any certification relating to your current position, achieved during your employment with us. Only one Certification Bonus per calendar year may be awarded per employee. Only current, active employees will be eligible to receive this bonus. It will be awarded 90 days after the Synectics office has received documentation confirming the successful completion of the certification.
Synectics is an equal opportunity employer.
Full-time