Scientist Cellular Genomics

Job Description

Job Description:

Responsible for generating and processing single-cell, spatial, and functional genomics data, as well as supporting standard immunoprofiling activities such as cell culture and flow cytometry.

Follow existing lab standard operating procedures to: Participate in sample collection of murine and human tissues, including the preparation of tubes, interfacing with in vivo scientists to retrieve samples, isolation of primary immune cells, and standard mammalian cell culture

Participate in sample preparation of murine and human tissues, including tissue fixation, dissociation, sectioning, and antibody staining

Generate spatial and single-cell data via a number of commercial workflows, including 10x Genomics and Parse Technologies

Interpret quality control metrics for spatial, single-cell and cytometry experiments

Typical bench work, including sitting, pipetting, lifting <10lb items

Reports to a scientific director of the Systems Immunology Lab

Collaborates with and supports several multi-disciplinary experimental teams on a per-project basis

REQUIREMENTS

Masters + 3 years of experience in Biology, Immunology, or a related field; OR

PhD +0 yrs experience in Biology, Immunology, or a related field

3+ years of hands-on experience with standard immunoprofiling technologies, including:

Flow Cytometry

Single-cell library preparation (ideally 10x Genomics or Parse Technology)

Preparation and loading of Illumina sequencing libraries

Bonus: generation of spatial transcriptomics data (any technology)

3+ years of experience with primary immune cells, including:

Primary immune cell isolation

Maintenace of immune cell lines

Cell culture and in vitro stimulation of primary immune cells

Bonus: experience with CRISPR mediated functional genomics, including electroporation of primary immune cells

Benefits:

Healthcare Insurance: Synectics offers eligible employees and their dependents healthcare coverage through BlueCross BlueShield of Illinois. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics. Premiums are subsidized by Synectics.

Dental Insurance: Synectics offers eligible employees and their dependents a dental plan through MetLife. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.

Vision Insurance: Synectics offers eligible employees vision insurance through VSP. Eligibility begins on the 1st day of the calendar month following 60 days of continuous full time employment with Synectics.401(k) Plan: The Synectics Inc. Investment Savings Retirement Plan. Synectics offers all employees who are 21 years of age or older the opportunity to invest in the 401(k) Plan on the first enrollment date that is at least 30 days after employment begins. Enrollment dates are each January 1st, April 1st, July 1st, and October 1st.

Technical Certification Bonus: Synectics is pleased to award its employees a bonus of up to $500 for an approved professional certification. In determining the bonus amount, Synectics will consider the cost of the test(s) for any certification relating to your current position, achieved during your employment with us. Only one Certification Bonus per calendar year may be awarded per employee. Only current, active employees will be eligible to receive this bonus. It will be awarded 90 days after the Synectics office has received documentation confirming the successful completion of the certification.

Synectics is an equal opportunity employer.

Full-time